Frontiers in Cell and Developmental Biology

Original Research

Published on 22 Aug 2025

Lactate modulates the function of myeloid-derived suppressor cells via Ten-Eleven-Translocation-2-mediated demethylation of glucocorticoid-inducible kinase 1 in lung cancer model

in Cancer Cell Biology

Ying Chu
Hua Shen
Qiu Li
Bo Shen
Yan Zhang
Deqiang Wang
Wei Zhu
Shengjun Wang
Jie Ma

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1565993

290 views

Review

Published on 22 Aug 2025

Targeting Wnt-driven metabolic adaptations in cancer: integrating glycolysis, glutaminolysis, IDO1-mediated immune evasion, and therapeutic delivery strategies

in Cancer Cell Biology

Eric Flores-Hernández
Grace Binder
Kuo-Ching Mei
Nydia Tejeda-Muñoz

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1622218

376 views

Review

Published on 22 Aug 2025

Developments in the study of the role of lactate metabolism in the genesis and progression of thyroid cancer

in Cancer Cell Biology

Lei Shi
Xuyang Zhong
Jiafeng Liu
Yong Ying
Zibing Liao
Jin Liu
Liwen Zhao
Jianing Zhong
Xiangtai Zeng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1640454

222 views

Original Research

Accepted on 21 Aug 2025

Interplay of KIR2DL5, nitric oxide, and tobacco smoking in predisposition to bladder cancer

in Cancer Cell Biology

Inmaculada Ruiz-Lorente
Lourdes Gimeno
Alicia López Abad
Pedro López Cubillana
Tomás Fernández Aparicio
Lucas Jesús Asensio Egea
Juan Moreno Avilés
Gloria Doñate Iñiguez
Pablo Luis Guzmán Martínez-Valls
Gerardo Server

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1632101

121 views

Review

Published on 21 Aug 2025

Gut microbiota interplay with autophagy-EMT dynamics in colorectal cancer

in Cancer Cell Biology

Tiziana Vescovo
Giulio Bontempi
Mohammadreza Bayat
Lucia Piredda
Marco Fidaleo
Raffaele Strippoli
Manuela Antonioli

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608248

476 views

Review

Published on 20 Aug 2025

Pannexin channels in inflammation and tumorigenesis

in Cancer Cell Biology

Mengmeng Jiang
Xiaojia Li
Keping Xie

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1647765

261 views

Original Research

Accepted on 18 Aug 2025

Investigating the Metabolic Reprogramming Mechanisms in Diabetic Nephropathy: A Comprehensive Analysis Using Bioinformatics and Machine Learning

in Cancer Cell Biology

Shan He
Yi Wei Chen
Jian Ye
Yu Wang
QinKai Chen
Siyi Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1630708

141 views

Original Research

Accepted on 18 Aug 2025

Variable expression of hepatic genes in different liver tumor cell lines: conclusions for drug testing

in Cancer Cell Biology

Monika Joanna Wisniewska
Agnieszka Wencel
Malgorzata Jakubowska
Joanna Agata Motyl
Krzysztof Dudek
Beata Burzynska
Dorota Genowefa Pijanowska
Krzysztof Dariusz Pluta

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1646602

130 views

Review

Accepted on 18 Aug 2025

Interplay of Replication Stress Response and Immune Microenvironment in High-Grade Serous Ovarian Cancer

in Cancer Cell Biology

Laura Venegas
Stephanie Lheureux

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1638964

Original Research

Published on 15 Aug 2025

Identification of progression-related genes and construction of prognostic model for chronic kidney disease by machine learning

in Cancer Cell Biology

Bingkun Zhou
Hu Zhou
Xiaodong Huang
Shijie Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1627355

488 views

Mini Review

Accepted on 14 Aug 2025

Unwinding new therapeutic opportunities in rhabdomyosarcoma: the role of RNA helicase DDX5

in Cancer Cell Biology

VALERIA BIANCONI
Chiara Mozzetta

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1662619

150 views

Original Research

Published on 14 Aug 2025

Efficacy of bleomycin and sirolimus in inhibiting CD31+ endothelial cell proliferation in noninvoluting congenital hemangiomas

in Cancer Cell Biology

Yanan Li
Chuan Wang
Yi Li
Xinglong Zhu
Ji Bao
Yi Ji

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1629770

281 views

Original Research

Accepted on 13 Aug 2025

Comprehensive analysis of the papillary thyroid carcinoma identifies CSGALNACT1 as a proliferation driver and prognostic biomarker

in Cancer Cell Biology

Yu Zhao
Juan Zhang
Yong Yao
Linna Yu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1638348

142 views

Original Research

Accepted on 12 Aug 2025

An Integrative Pan-Cancer Analysis of USP37 and Functional Validation in Pancreatic Cancer

in Cancer Cell Biology

Jiafei Chen
Liang Lin
Dongxing Chen
Jingui Wang
Wuhan Zhou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1659747

169 views

Review

Published on 12 Aug 2025

The role of LKB1 in prostate cancer: implications for tumor progression and therapy

in Cancer Cell Biology

Yuwei Liang
Hongliang Cao
Zhijun Tang
Shuxin Li
Gang Yang
Shuai Dong
Hao Du
Jinguo Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1629844

441 views

Review

Accepted on 11 Aug 2025

Reprogramming Cancer Immunity with Next-Generation Combination Therapies

in Cancer Cell Biology

Nikolaos C. Kyriakidis
Carolina E Echeverría
Jhommara Bautista
Jhoan Sebastián Rivera Orellana
María José Ramos-Medina
Camila Salazar
Juan Sebastian Izquierdo-Condoy
Esteban Ortiz-Prado
Santiago Guerrero
Andrés López-Cortés

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1652047

248 views