Frontiers in Cell and Developmental Biology

Original Research

Published on 30 Jul 2025

Exosomal miR-2137 from cadmium-treated hepatocytes drives renal ferroptosis via GPX4 suppression and is alleviated by selenium

in Cellular Biochemistry

Qian Wen
Meiyan Qi
Yanjun Wu
Weiwei Ji
Lixing Zhan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1585106

1,932 views
1 citation

Opinion

Published on 21 Jul 2025

Metagenome-informed metaproteomics methodology: a new breakthrough in revealing the mechanisms of host-microbiota-diet interactions in inflammatory bowel disease

in Cellular Biochemistry

Suqin Zhang
Qi Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1634974

1,565 views

Review

Published on 25 Jun 2025

Targeting alveolar epithelial cell metabolism in pulmonary fibrosis: Pioneering an emerging therapeutic strategy

in Cellular Biochemistry

Tengkun Dai
Yidan Liang
Xin Li
Jiamin Zhao
Guangqin Li
Qihong Li
Lin Xu
Juanjuan Zhao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608750

4,465 views
2 citations

Review

Published on 25 Jun 2025

Research progress of ferroptosis in acute kidney injury

in Cellular Biochemistry

Lin Zhang
Feng Luo
Nan Yuan
Jiaming Yin
Bing Shen
Yalin Chai
Lijie Sun
Xuan Wang
Le Yin
Congjuan Luo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1614156

4,534 views
5 citations

Mini Review

Published on 23 Jun 2025

The impact of sulfonylureas on diverse ion channels: an alternative explanation for the antidiabetic actions

in Cellular Biochemistry

Xian-Tao Li
Meng-Ze Yun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1528369

3,721 views
4 citations

Original Research

Published on 19 Jun 2025

Bioinformatics-based screening and validation of PANoptosis-related biomarkers in periodontitis

in Cellular Biochemistry

Qing Sun
JinYue Hu
RuYue Wang
ShuiXiang Guo
GeGe Zhang
Ao Lu
Xue Yang
LiNa Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1619002

4,165 views

Review

Published on 10 Jun 2025

Targeting microglia polarization with Chinese herb-derived natural compounds for neuroprotection in ischemic stroke

in Cellular Biochemistry

Lu Yu
Yin Dong
Mincheng Li
Huifang Liu
Cuina Yan
Xiaoxian Li
Yuehua Gu
Liwei Wang
Chuan Xu
Jie Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1580479

3,606 views
1 citation

Original Research

Published on 03 Jun 2025

Establishment of human periodontal ligament cell lines with ALPL mutations to mimic dental aspects of hypophosphatasia

in Cellular Biochemistry

Jana Schiffmaier
Sofia Rehling
Katharina Marnet
Angela Borst
Drenka Trivanović
Denitsa Docheva
Franz Jakob
Stephanie Graser
Marietta Herrmann
Daniel Liedtke

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1572571

2,815 views

Original Research

Published on 23 May 2025

SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome

in Cellular Biochemistry

Sisi Yan
Bing Qu
Yu Chen
Qiuji Wu
Jinli Ding
Hui Qiu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1585987

3,322 views

Review

Published on 16 May 2025

The new insight into the role of hydroxyproline in metabolism of cancer cells

in Cellular Biochemistry

Magda Chalecka
Justyna Magdalena Hermanowicz
Jerzy Palka
Arkadiusz Surazynski

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1556770

6,156 views
2 citations

Original Research

Published on 08 May 2025

Exploring the role of cell cycle regulation in human mature adipocyte dedifferentiation

in Cellular Biochemistry

Giada Ostinelli
Marie-Frédérique Gauthier
Nathalie Vernoux
Emilie Bernier
Tristan Dubé
Simon Marceau
Stéfane Lebel
Marie-Ève Tremblay
André Tchernof

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1547836

2,451 views
1 citation

Original Research

Published on 02 May 2025

Correlation study and full management of metabolic syndrome and sperm DNA fragmentation index, a regional multicentre prospective long term follow-up study from Anhui, China

in Cellular Biochemistry

Dongsheng Ma
Jianhong Xi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1586069

2,581 views
4 citations

Original Research

Published on 28 Apr 2025

rFIP-nha activates macrophages towards a pro-inflammatory phenotype via AIM2 inflammasome modulation

in Cellular Biochemistry

Yusi Liu
Zhen Li
Harry Wichers
Shanna Bastiaan-Net
Tamara Hoppenbrouwers

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1533742

2,639 views

Review

Published on 25 Apr 2025

Protein misfolding and mitochondrial dysfunction in glaucoma

in Cellular Biochemistry

Arunkumar Venkatesan
Audrey M. Bernstein

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1595121

5,730 views
10 citations

Review

Published on 24 Apr 2025

ANXA5: related mechanisms of osteogenesis and additional biological functions

in Cellular Biochemistry

Ming Jin
Jingrun Zhang
Yimeng Sun
Ge Liu
Xiaowei Wei

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1553683

3,620 views
7 citations

Original Research

Published on 17 Apr 2025

Comprehensive transcriptomic analysis integrating bulk and single-cell RNA-seq with machine learning to identify and validate mitochondrial unfolded protein response biomarkers in patients with ischemic stroke

in Cellular Biochemistry

Lu Zhang
Lei Yue
Peng Jia
Ziqi Cheng
Jiwen Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1582252

5,151 views

Original Research

Published on 10 Apr 2025

Metabolomic profiling and biomarker identification for early detection and therapeutic targeting of doxorubicin-induced cardiotoxicity

in Cellular Biochemistry

Jingjing Ding
Xianzhen Feng
Zhongqing Xu
Hong Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1543636

3,226 views
3 citations

Review

Published on 07 Apr 2025

Integration of MicroRNAs with nanomedicine: tumor targeting and therapeutic approaches

in Cellular Biochemistry

Pelin Telkoparan-Akillilar
Silvia Chichiarelli
Paolo Tucci
Luciano Saso

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1569101

4,097 views
13 citations

Review

Published on 28 Mar 2025

Unveiling the impact of ERAP1 and ERAP2 on migration, angiogenesis and ER stress response

in Cellular Biochemistry

Irma Saulle
Alessandra Velia Vitalyos
Daniel D’Agate
Mario Clerici
Mara Biasin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564649

2,966 views

Review

Published on 28 Mar 2025

Lactylation in CNS disorders: mechanisms, cellular function, and disease relevance

in Cellular Biochemistry

Jiaxin Tian
Tongyu Zhang
Ruidan Zhang
Sijia Hao
Jingyu Dong
Yiyan Chen
Jinpeng Zhou
Yang Tian

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1566921

6,405 views
3 citations

Original Research

Published on 27 Mar 2025

Quantitation of global histone post-translational modifications reveal anti-inflammatory epigenetic mechanisms of liquiritigenin based on the optimized super-SILAC strategy

in Cellular Biochemistry

Ping Liu
Jun Zhang
Jingdan Zhang
Yucheng Yuan
Zhiqing Liu
Sixian Chen
Kaifeng Chen
Li Dong
Zhiyuan Cheng
Yinan Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1566567

3,316 views
3 citations

Review

Published on 26 Mar 2025

SIRT1 and exercise-induced bone metabolism: a regulatory nexus

in Cellular Biochemistry

Lijie Liu
Jiale Zhang
Runhong Cui
Na Wang
Yun Zhang
Lifei Liu
Xinan Zhang
Qingfeng Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1522821

4,303 views
3 citations

Review

Published on 26 Mar 2025

Navigating redox imbalance: the role of oxidative stress in embryonic development and long-term health outcomes

in Cellular Biochemistry

Satya Srirama Karthik Divvela
Marialucia Gallorini
Morris Gellisch
Gaurav Deepak Patel
Luciano Saso
Beate Brand-Saberi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1521336

5,483 views
17 citations

Original Research

Published on 24 Mar 2025

Exosome-mediated dual drug delivery of curcumin and methylene blue for enhanced cognitive function and mechanistic elucidation in Alzheimer’s disease therapy

in Cellular Biochemistry

Dongxin Yang
Zhuofen Deng
Hai Zhou
Qingshang Zhang
Xibing Zhang
Jun Gong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1562565

5,169 views
8 citations

811 articles

articles

Exosomal miR-2137 from cadmium-treated hepatocytes drives renal ferroptosis via GPX4 suppression and is alleviated by selenium

Metagenome-informed metaproteomics methodology: a new breakthrough in revealing the mechanisms of host-microbiota-diet interactions in inflammatory bowel disease

Targeting alveolar epithelial cell metabolism in pulmonary fibrosis: Pioneering an emerging therapeutic strategy

Research progress of ferroptosis in acute kidney injury

The impact of sulfonylureas on diverse ion channels: an alternative explanation for the antidiabetic actions

Bioinformatics-based screening and validation of PANoptosis-related biomarkers in periodontitis

Targeting microglia polarization with Chinese herb-derived natural compounds for neuroprotection in ischemic stroke

Establishment of human periodontal ligament cell lines with ALPL mutations to mimic dental aspects of hypophosphatasia

SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome

The new insight into the role of hydroxyproline in metabolism of cancer cells

Exploring the role of cell cycle regulation in human mature adipocyte dedifferentiation

Correlation study and full management of metabolic syndrome and sperm DNA fragmentation index, a regional multicentre prospective long term follow-up study from Anhui, China

rFIP-nha activates macrophages towards a pro-inflammatory phenotype via AIM2 inflammasome modulation

Protein misfolding and mitochondrial dysfunction in glaucoma

ANXA5: related mechanisms of osteogenesis and additional biological functions

Comprehensive transcriptomic analysis integrating bulk and single-cell RNA-seq with machine learning to identify and validate mitochondrial unfolded protein response biomarkers in patients with ischemic stroke

Metabolomic profiling and biomarker identification for early detection and therapeutic targeting of doxorubicin-induced cardiotoxicity

Integration of MicroRNAs with nanomedicine: tumor targeting and therapeutic approaches

Unveiling the impact of ERAP1 and ERAP2 on migration, angiogenesis and ER stress response

Lactylation in CNS disorders: mechanisms, cellular function, and disease relevance

Quantitation of global histone post-translational modifications reveal anti-inflammatory epigenetic mechanisms of liquiritigenin based on the optimized super-SILAC strategy

SIRT1 and exercise-induced bone metabolism: a regulatory nexus

Navigating redox imbalance: the role of oxidative stress in embryonic development and long-term health outcomes

Exosome-mediated dual drug delivery of curcumin and methylene blue for enhanced cognitive function and mechanistic elucidation in Alzheimer’s disease therapy