Frontiers in Cell and Developmental Biology | Molecular and Cellular Pathology

Original Research

Published on 27 Jan 2026

Establishing and validating a predictive model for long-term control outcomes following orthokeratology lenses wear: a five-year cohort study

in Molecular and Cellular Pathology

Zixun Wang
Xiaoling Zhang
Xiaoxue Hu
Hui Miao
Shujun Zhang
Feng Chang
Ruihua Wei
Zheng Guo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1743506

589 views

Review

Accepted on 26 Jan 2026

Etiology, diagnosis and treatment of lumbar disc degeneration: a focus on the mechanism of action of Piezo1 and research perspectives

in Molecular and Cellular Pathology

Yan Gong
Zhaojun Cheng
Jiahui He
Yanchi Gan
Xiaobing Jiang
Jintao Liu

Frontiers in Cell and Developmental Biology

154 views

Review

Accepted on 26 Jan 2026

Hepatic mitochondrial signaling as a systemic hub: inter-organ communication networks in aging and aging-related diseases

in Molecular and Cellular Pathology

Yishuo Ji
Ying Wang
Xiaowei Yu
Yi Jin
Kai Zhao
Yue Hu
Zhenglin He

Frontiers in Cell and Developmental Biology

267 views

Original Research

Published on 26 Jan 2026

Quantitative color fundus photography parameters as potential biomarkers of axial length progression: evidence from a machine learning cohort study

in Molecular and Cellular Pathology

Zixun Wang
Feifei Han
Xiaoling Zhang
Jingjie Ding
Jingtao Yu
Xueshuo Xie
Zhiqing Li
Bei Du
Ruihua Wei

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1753213

509 views

Opinion

Accepted on 23 Jan 2026

The enigma of nuclear FMRP: Facts and Myths

in Molecular and Cellular Pathology

Edouard W Khandjian
Laetitia Davidovic

Frontiers in Cell and Developmental Biology

732 views

Original Research

Published on 23 Jan 2026

VEGF-A isoforms induce the expression of APLN in endothelial cells during human prenatal lung development

in Molecular and Cellular Pathology

Antony Hoarau
Andrew Frauenpreis
Randa Belgacemi
Emma Loeffler
Osshaya Maalouf
Ian A. Glass
Denise Al Alam
Soula Danopoulos

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1729884

835 views

Review

Published on 22 Jan 2026

Oral submucosal fibrosis: a comprehensive review on pathogenesis, diagnosis, therapeutics and computational advances

in Molecular and Cellular Pathology

Chinmay Nitin. Mokal
Mrinmoy Das
Sridhar Hannenhalli
Piyush Agrawal

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1754209

1,150 views

Original Research

Published on 22 Jan 2026

Loss of CAMKK2 and iron-transport proteins—transferrin and its receptor—in the Alzheimer’s disease hippocampus: link to tau pathology

in Molecular and Cellular Pathology

Mohammad Golam Sabbir
Behzad Mansouri
Bram Ramjiawan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1716718

841 views

Mini Review

Accepted on 13 Jan 2026

Phosphatases in Tumor Cell Immune Escape: A Perspective Based on the Camouflage, Coercion, Cytoprotection

in Molecular and Cellular Pathology

Chencheng Zhang
Shudong Zhu

Frontiers in Cell and Developmental Biology

244 views

Review

Published on 12 Jan 2026

Mechanisms and therapeutic prospects of hypoxia-inducible factor 1-alpha in acute kidney injury: a systematic review

in Molecular and Cellular Pathology

Peng Kang
Fan Cheng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1660433

1,052 views

Review

Published on 12 Jan 2026

Proteolytic enzyme models as tunable preclinical platforms for investigating intervertebral disc degeneration

in Molecular and Cellular Pathology

Jan Gewiess
Annamarie D’Intino
Alejandra Santos
Mauro Alini
Andrea J. Vernengo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1683282

747 views

Review

Published on 12 Jan 2026

Progress on the mechanism of Polycystin-1 in bone remodeling

in Molecular and Cellular Pathology

JinShi Guo
GuangXuan Hu
XiaoYing Li
XueJie Yi
Bo Chang
Tao Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1693704

703 views

Review

Published on 12 Jan 2026

Impact of follistatin-like 1 on cardiac repair processes following myocardial infarction

in Molecular and Cellular Pathology

Fang He
Xueying Wang
Yongbin Man
Qianqian Xu
Xuejie Yi
Jiao Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1746363

860 views

Original Research

Published on 09 Jan 2026

Development of a novel prognostic model based on TRPM4-Induced sodium overload–mediated cell death in kidney cancer

in Molecular and Cellular Pathology

Wei Wang
Duo Zhao
Zijun Zhou
Bin Chen
Changwen Zhang
E. Du
Longchao Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1755318

996 views

Original Research

Published on 08 Jan 2026

Orally administered fluorescein angiography for ultra-wide-field imaging: is a safe and effective modality across different age groups and fundus diseases?

in Molecular and Cellular Pathology

Yuke Ji
Xinya Hu
Yuting Hu
Sisi Lai
Xiaofeng Lu
Xuan Li
Zixiao Liu
Shaochong Zhang
Weihua Yang
Xue Yao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1733128

618 views

Original Research

Published on 07 Jan 2026

Deciphering the immunomodulatory mechanisms of Periplaneta americana L. extract CII-3: insight from integrated metabolomics and network pharmacology

in Molecular and Cellular Pathology

Yilin Wang
Yingxiang Wu
Xi Liu
Zhiyan Lu
Tianqian Li
Yang Jin
Yan Wang
Jiali Zhu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1718560

835 views

Original Research

Accepted on 06 Jan 2026

The Actin Regulator DBNL Is a Critical Mediator of Sympathetic Stress-Induced Bone Loss

in Molecular and Cellular Pathology

Qin Yin
Jun Gu
Ruijun Bai
Kai Zhao
Qiubo Wang
Yu Liu
Haifeng Li

Frontiers in Cell and Developmental Biology

208 views

Mini Review

Published on 06 Jan 2026

A primer on tRNAs, tRNA-m1A58 modification, and tRNA derivatives in T-cell activation

in Molecular and Cellular Pathology

Chuanxiang Zhao
Juxiang Shen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1683213

703 views

Original Research

Published on 06 Jan 2026

Macrophage-myofibroblast transition as a novel therapeutic target in shoulder stiffness: multi-omics study and experimental validation

in Molecular and Cellular Pathology

Beijie Qi
Weihan Yu
Hanyi Wang
Yuqi Li
Shuang Deng
Chengqing Yi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1727624

581 views

Review

Published on 05 Jan 2026

The varied functions of the giant muscle scaffold protein obscurin

in Molecular and Cellular Pathology

James Novac Di Paola
Frieder Schöck

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1689326

953 views

Original Research

Published on 30 Dec 2025

Fibroblast growth factor 9 activates fibroblast activation and drives the progress of shoulder stiffness

in Molecular and Cellular Pathology

Jian Xu
Weihan Yu
Yunkang Kang
Dongqiang Yang
Yanlong Liu
Wenzhi Bi
Haiyang Yu
Beijie Qi
Biao Guo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1731453

814 views

Original Research

Published on 29 Dec 2025

Integration of peripheral blood-based systemic inflammatory indices and retinal imaging using interpretable machine learning for predicting anti-VEGF treatment response in macular edema secondary to retinal vein occlusion

in Molecular and Cellular Pathology

Jiajun Li
Yao Lu
Qianzi Jin
Siqi Wu
Xiangzhong Xu
Qin Jiang
Keran Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1732963

1,019 views

Original Research

Published on 19 Dec 2025

Association of fibronectin 1 deregulation with tyrosine kinase inhibitor resistance in chronic myeloid leukemia

in Molecular and Cellular Pathology

Lina Tiedemann
Sivahari Prasad Gorantla
Philine Ahlf
Lucie Sophie Schmidt
Christiane Pott
Merit Litterst
Vicki Waetzig
Inga Nagel
Johanna Ruemenapp
Nikolas von Bubnoff

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1725857

1,090 views

Review

Published on 18 Dec 2025

The role of ADAR1 in human pathophysiology

in Molecular and Cellular Pathology

Jiahao Li
Yushan Xiao
Xiaofeng Li
Yan Dai

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1672970

1,483 views

2,488 articles

articles

Establishing and validating a predictive model for long-term control outcomes following orthokeratology lenses wear: a five-year cohort study

Etiology, diagnosis and treatment of lumbar disc degeneration: a focus on the mechanism of action of Piezo1 and research perspectives

Hepatic mitochondrial signaling as a systemic hub: inter-organ communication networks in aging and aging-related diseases

Quantitative color fundus photography parameters as potential biomarkers of axial length progression: evidence from a machine learning cohort study

The enigma of nuclear FMRP: Facts and Myths

VEGF-A isoforms induce the expression of APLN in endothelial cells during human prenatal lung development

Oral submucosal fibrosis: a comprehensive review on pathogenesis, diagnosis, therapeutics and computational advances

Loss of CAMKK2 and iron-transport proteins—transferrin and its receptor—in the Alzheimer’s disease hippocampus: link to tau pathology

Phosphatases in Tumor Cell Immune Escape: A Perspective Based on the Camouflage, Coercion, Cytoprotection

Mechanisms and therapeutic prospects of hypoxia-inducible factor 1-alpha in acute kidney injury: a systematic review

Proteolytic enzyme models as tunable preclinical platforms for investigating intervertebral disc degeneration

Progress on the mechanism of Polycystin-1 in bone remodeling

Impact of follistatin-like 1 on cardiac repair processes following myocardial infarction

Development of a novel prognostic model based on TRPM4-Induced sodium overload–mediated cell death in kidney cancer

Orally administered fluorescein angiography for ultra-wide-field imaging: is a safe and effective modality across different age groups and fundus diseases?

Deciphering the immunomodulatory mechanisms of Periplaneta americana L. extract CII-3: insight from integrated metabolomics and network pharmacology

The Actin Regulator DBNL Is a Critical Mediator of Sympathetic Stress-Induced Bone Loss

A primer on tRNAs, tRNA-m1A58 modification, and tRNA derivatives in T-cell activation

Macrophage-myofibroblast transition as a novel therapeutic target in shoulder stiffness: multi-omics study and experimental validation

The varied functions of the giant muscle scaffold protein obscurin

Fibroblast growth factor 9 activates fibroblast activation and drives the progress of shoulder stiffness

Integration of peripheral blood-based systemic inflammatory indices and retinal imaging using interpretable machine learning for predicting anti-VEGF treatment response in macular edema secondary to retinal vein occlusion

Association of fibronectin 1 deregulation with tyrosine kinase inhibitor resistance in chronic myeloid leukemia

The role of ADAR1 in human pathophysiology