Frontiers in Cell and Developmental Biology | Molecular and Cellular Pathology

Brief Research Report

Published on 25 Sep 2025

Genetic modulation of mitochondrial NAD+ regeneration does not prevent dopaminergic neuron dysfunction caused by mitochondrial complex I impairment

in Molecular and Cellular Pathology

Karis B. D’Alessandro
Enrico Zampese
Jenna L. E. Blum
Britta Kuusik
Alec Palmiotti
Shawn M. Davidson
Colleen R. Reczek
D. James Surmeier
Navdeep S. Chandel

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1650462

2,946 views

Review

Published on 24 Sep 2025

Epicardium-myocardium crosstalk orchestrates heart development

in Molecular and Cellular Pathology

Anika Nusrat
Mingfu Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1655878

2,597 views
1 citation

Original Research

Published on 11 Sep 2025

Diagnostic performance and generalizability of deep learning for multiple retinal diseases using bimodal imaging of fundus photography and optical coherence tomography

in Molecular and Cellular Pathology

Xingwang Gu
Yang Zhou
Jianchun Zhao
Hongzhe Zhang
Xinlei Pan
Bing Li
Bilei Zhang
Yuelin Wang
Song Xia
Hailan Lin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1665173

3,530 views

Original Research

Published on 09 Sep 2025

Artificial intelligence in cataract grading system: a LOCS III-based hybrid model achieving high-precision classification

in Molecular and Cellular Pathology

Gege Tang
Jie Zhang
Yingqi Du
Dexun Jiang
Yanhua Qi
Nan Zhou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1669696

5,100 views
2 citations

Review

Published on 08 Sep 2025

m6A: a novel strategy for osteoporosis treatment

in Molecular and Cellular Pathology

Chunlu Yan
Xiaolong Xiao
Fan Yang
Yangyang Shi
Qiao Wan
Yan Zhang
Fangyu An

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1603068

2,200 views

Original Research

Published on 04 Sep 2025

Artificial intelligence applications facilitate decision-making in cataract surgery for highly myopic patients

in Molecular and Cellular Pathology

Kaimeng Su
Wenwen He
Haifeng Jiang
Keke Zhang
Jiao Qi
Jiaqi Meng
Yu Du
Kaiwen Cheng
Xiaoxin Hu
Dongling Guo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1613634

2,476 views
1 citation

Original Research

Published on 03 Sep 2025

The mechanosensitive protein ANTXR1 is involved in maintaining cartilage homeostasis in post-traumatic osteoarthritis

in Molecular and Cellular Pathology

Zhuangzhuang Miao
Junjie Liu
Pengfei Cheng
Yinghao Shen
Jiahang Tang
Jiajie Zhu
Weiwei Liu
Xuchang Zhou
Hongying Jing

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1625333

2,470 views

Review

Published on 01 Sep 2025

Examination of degenerative and damaged glenohumeral joint tissue samples with calorimetric analyses

in Molecular and Cellular Pathology

Dénes Lőrinczy
András Bata
László Bogdán
Árpád Pillér
Laszlo G. Nöt

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1653732

1,327 views

Original Research

Published on 01 Sep 2025

Identification of the key immune gene NR3C1 as a diagnostic biomarker in differentiating ovarian borderline tumors from benign tumors

in Molecular and Cellular Pathology

Shiying Chen
Yumin Ke
Yajing Xie
Zhimei Zhou
Weihong Chen
Li Huang
Liying Sheng
Yueli Wang
Shunlan Liu
Zhuna Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1602192

2,005 views

Original Research

Published on 29 Aug 2025

Fibroblast growth factor 19 regulates polycystic ovary syndrome progression via FGFR4-ERK-NRF2 pathway

in Molecular and Cellular Pathology

Junjie Qu
Meiting Qiu
Jingyun Wang
Zhiqin Chen
Miaoxin Chen
Xiaoming Teng
Yiran Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1626938

2,426 views
1 citation

Original Research

Published on 29 Aug 2025

Maternal and fetal outcomes in 151 cases of thrombocytopenia in pregnancy

in Molecular and Cellular Pathology

Chinwe Oluchi-Amaka Ibeh
Feng Guo
Xiuhua Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608647

2,545 views

Original Research

Published on 22 Aug 2025

Refractive error after phacoemulsification combined with intraocular lens implantation in primary angle-closure glaucoma: a multifactorial analysis of biometric parameters and surgical strategies

in Molecular and Cellular Pathology

Yong Liu
Kuanrong Dang
Di Gong
Simin Deng
Yin Deng
Junhong Guo
Xiaoli Shen
Jiantao Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1654719

2,438 views

Original Research

Published on 21 Aug 2025

Genome-wide DNA methylation analysis identifies kidney epigenetic dysregulation in a cystinosis mouse model

in Molecular and Cellular Pathology

M. N. Rossi
A. Ciolfi
V. Matteo
L. Pedace
C. Nardini
E. Loricchio
I. Caiello
F. Bellomo
A. Taranta
E. De Leo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1638123

2,326 views
3 citations

Review

Published on 21 Aug 2025

Mitochondrial dysfunction in diabetic ulcers: pathophysiological mechanisms and targeted therapeutic strategies

in Molecular and Cellular Pathology

Yu Pan
Lin Chen
Yan Chen
Elizabeth Rosalind Thomas
Shiying Zhou
You Yang
Kezhi Liu
Jianming Wu
Xiang Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1625474

4,598 views
2 citations

Original Research

Published on 18 Aug 2025

Genetic predisposition to immune dysregulation and extracellular matrix remodeling in cardiac arrhythmia reveals potential mediation by SPP1+ macrophages

in Molecular and Cellular Pathology

Jie-Yuan Jin
Shuai Guo
Yao Deng
Ya-Qin Chen
Chen Liang
Yu-Jie Jiang
Wang Zhao
Rong Xiang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1611663

3,156 views
1 citation

Original Research

Published on 15 Aug 2025

Differential expression profiles and bioinformatics analysis of microRNAs in brown adipose tissue dysfunction induced by chronic intermittent hypoxia in obstructive sleep apnea

in Molecular and Cellular Pathology

Meilin Ji
Yaopeng Guo
Jinjie Zhang
Shu Lin
Liangyi Li
Qingshi Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1598018

2,004 views

Review

Published on 14 Aug 2025

Role and mechanism of Integrin α5β1 in bone formation and disease

in Molecular and Cellular Pathology

Xiaoying Li
Guangxuan Hu
Jinshi Guo
Bo Chang
Xuejie Yi
Tingting Yao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1632710

3,632 views
2 citations

Correction

Published on 13 Aug 2025

Correction: Evaluating multiple large language models on orbital diseases

in Molecular and Cellular Pathology

Qi-Chen Yang
Yan-Mei Zeng
Hong Wei
Cheng Chen
Qian Ling
Xiao-Yu Wang
Xu Chen
Yi Shao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1664098

1,046 views

Original Research

Published on 13 Aug 2025

HAX1, gene responsible for Kostmann syndrome, regulates gingival epithelial barrier function via intracellular trafficking of JAM1

in Molecular and Cellular Pathology

Keita Tanigaki
Tsukasa Tamamori
Naoko Sasaki
Risako Matsumura
Shunsuke Yamaga
Akito Sakanaka
Atsuo Amano
Michiya Matsusaki
Hiroki Takeuchi
Masae Kuboniwa

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1624718

2,039 views
1 citation

Editorial

Published on 12 Aug 2025

Editorial: Cellular and molecular mechanisms of lung regeneration, repair, and fibrosis, volume II

in Molecular and Cellular Pathology

Yong Qiu
Xiao Xiao Tang
Shigeyuki Shichino
Prem Prakash Kushwaha
Yan Y. Sanders
Remo Castro Russo
Chunheng Mo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1653034

2,858 views

Original Research

Published on 12 Aug 2025

Early diagnosis of coronary heart disease based on retinal microvascular parameters of OCTA

in Molecular and Cellular Pathology

Shijia Zhou
Qifeng Yan
Jiaqi Guo
Wenming He
Yitian Zhao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1654159

2,444 views
1 citation

Review

Published on 11 Aug 2025

Exercise in atherosclerosis: its beneficial effects and underlying mechanism

in Molecular and Cellular Pathology

Meng-ting Yin
Liang Guo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1598794

5,409 views
1 citation

Review

Published on 07 Aug 2025

Bone marrow adipocytes: key players in vascular niches, aging, and disease

in Molecular and Cellular Pathology

Yonggang Fan
Mai Elkhalek
Yuheng Zhang
Lu Liu
Qi Tian
Nareekarn Chueakula
Saravana K. Ramasamy
Rinkoo Dalan
Shukry J. Habib
Anjali P. Kusumbe

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1633801

4,994 views
3 citations

Original Research

Published on 07 Aug 2025

Hartnup disease-causing SLC6A19 mutations lead to B0AT1 aberrant trafficking and ACE2 mis-localisation implicating the endoplasmic reticulum protein quality control

in Molecular and Cellular Pathology

Nesreen F. Alkhofash
Bassam R. Ali

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1589534

2,882 views
1 citation

2,488 articles

articles

Genetic modulation of mitochondrial NAD+ regeneration does not prevent dopaminergic neuron dysfunction caused by mitochondrial complex I impairment

Epicardium-myocardium crosstalk orchestrates heart development

Diagnostic performance and generalizability of deep learning for multiple retinal diseases using bimodal imaging of fundus photography and optical coherence tomography

Artificial intelligence in cataract grading system: a LOCS III-based hybrid model achieving high-precision classification

m6A: a novel strategy for osteoporosis treatment

Artificial intelligence applications facilitate decision-making in cataract surgery for highly myopic patients

The mechanosensitive protein ANTXR1 is involved in maintaining cartilage homeostasis in post-traumatic osteoarthritis

Examination of degenerative and damaged glenohumeral joint tissue samples with calorimetric analyses

Identification of the key immune gene NR3C1 as a diagnostic biomarker in differentiating ovarian borderline tumors from benign tumors

Fibroblast growth factor 19 regulates polycystic ovary syndrome progression via FGFR4-ERK-NRF2 pathway

Maternal and fetal outcomes in 151 cases of thrombocytopenia in pregnancy

Refractive error after phacoemulsification combined with intraocular lens implantation in primary angle-closure glaucoma: a multifactorial analysis of biometric parameters and surgical strategies

Genome-wide DNA methylation analysis identifies kidney epigenetic dysregulation in a cystinosis mouse model

Mitochondrial dysfunction in diabetic ulcers: pathophysiological mechanisms and targeted therapeutic strategies

Genetic predisposition to immune dysregulation and extracellular matrix remodeling in cardiac arrhythmia reveals potential mediation by SPP1+ macrophages

Differential expression profiles and bioinformatics analysis of microRNAs in brown adipose tissue dysfunction induced by chronic intermittent hypoxia in obstructive sleep apnea

Role and mechanism of Integrin α5β1 in bone formation and disease

Correction: Evaluating multiple large language models on orbital diseases

HAX1, gene responsible for Kostmann syndrome, regulates gingival epithelial barrier function via intracellular trafficking of JAM1

Editorial: Cellular and molecular mechanisms of lung regeneration, repair, and fibrosis, volume II

Early diagnosis of coronary heart disease based on retinal microvascular parameters of OCTA

Exercise in atherosclerosis: its beneficial effects and underlying mechanism

Bone marrow adipocytes: key players in vascular niches, aging, and disease

Hartnup disease-causing SLC6A19 mutations lead to B0AT1 aberrant trafficking and ACE2 mis-localisation implicating the endoplasmic reticulum protein quality control