Frontiers in Cell and Developmental Biology | Molecular and Cellular Pathology

Original Research

Published on 06 Aug 2025

Integrated single-cell and bulk transcriptome analysis reveal lactate metabolism-related signature and T cell alteration in atrial fibrillation

in Molecular and Cellular Pathology

Xianglin Long
Junxi Li
Yeshen Zhang
Zhihui Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1644702

2,614 views

Original Research

Published on 06 Aug 2025

Fufang Duzhong Jiangu granule (FFDZ) ameliorates osteoarthritis development through maintaining subchondral bone homeostasis

in Molecular and Cellular Pathology

Houfu Ling
Jianbo Xu
Qinghe Zeng
Zhen Fang
Liangyan Cheng
Wenhua Yuan
Jiali Chen
Yuliang Huang
Songfeng Hu
Hongting Jin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1610007

2,706 views

Review

Published on 06 Aug 2025

Matrisome remodeling in the myocardium of hypertrophic cardiomyopathy; novel targets for molecular diagnostics

in Molecular and Cellular Pathology

Ayman M. Ibrahim
Hasnaa A. Elfawy
Cesare M. Terracciano
Magdi Yacoub

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1641584

2,547 views

Review

Published on 06 Aug 2025

Research progress in deep learning-based fundus image analysis for the diagnosis and prediction of hypertension-related diseases

in Molecular and Cellular Pathology

Ping Li
Juan Tao
Quan Yuan
Rongqing Zhang
Peng Gao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608994

4,049 views
1 citation

Original Research

Published on 05 Aug 2025

A new digital biomarker of Demodex blepharitis: energy curve of the meibomian edge

in Molecular and Cellular Pathology

Minjia Wang
Xiaoyu Chen
Kesheng Wang
Kunhui Xu
Xinxin Yu
Qi Dai
Min Ren

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1627327

2,125 views

Review

Published on 05 Aug 2025

The neural signature of high myopia: structural and functional brain alterations and their cognitive-emotional associations

in Molecular and Cellular Pathology

Xuan Li
Kuan Zhao
Boling Deng
Zhengzheng Wu
Ling Wei

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1634553

3,326 views
1 citation

Review

Published on 05 Aug 2025

Advances in cfDNA research for pregnancy-related diseases

in Molecular and Cellular Pathology

Yimei Meng
Yu Yan
Xiaoshan Yue
Yan Li
Yanxiang Mo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1600532

3,202 views
1 citation

Original Research

Published on 01 Aug 2025

Predicting visual acuity of treated ocular trauma based on pattern visual evoked potentials by machine learning models

in Molecular and Cellular Pathology

Hongxia Hao
Jiemin Chen
Yifei Yan
Qi Zhang
Zhilu Zhou
Wentao Xia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1619956

1,499 views

Mini Review

Published on 31 Jul 2025

Beyond vision loss: the impact of glaucoma on the brain

in Molecular and Cellular Pathology

Trinita Jude Hamilton
Bettina E. Kalisch

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1588561

2,727 views

Original Research

Published on 31 Jul 2025

Molecular signatures of preeclampsia subtypes determined through integrated weighted gene co-expression network analysis and differential gene expression analysis of placental transcriptomics

in Molecular and Cellular Pathology

Luhao Han
Fabricio da Silva Costa
Anthony Perkins
Olivia Holland

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1635878

2,795 views
4 citations

Editorial

Published on 29 Jul 2025

Editorial: Lymphatic system: organ specific functions in health and disease, volume II

in Molecular and Cellular Pathology

Zoltán Jakus
Young-Kwon Hong
Tsutomu Kume

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1659266

1,963 views

Original Research

Published on 28 Jul 2025

Altered endoplasmic reticulum calcium loading in human PLN-R14del cardiomyopathy

in Molecular and Cellular Pathology

Willem Borbein
Lukas Dahmlos
Umber Saleem
Marina Reinsch
Ingke Braren
Thomas Schulze
Birgit Klampe
Friederike Cuello
Justus Stenzig
Thomas Eschenhagen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1627985

2,246 views
1 citation

Original Research

Published on 24 Jul 2025

Automated detection of diabetic retinopathy lesions in ultra-widefield fundus images using an attention-augmented YOLOv8 framework

in Molecular and Cellular Pathology

Lei-Si Hu
Jie Wang
Heng-Ming Zhang
Hai-Yu Huang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608580

2,208 views
1 citation

Original Research

Published on 23 Jul 2025

Saliva-derived exosomes regulate fibroblast metabolic reprogramming in skin wound healing

in Molecular and Cellular Pathology

Sijia Song
Rong Xiang
Siyu Chen
Jianbo Wu
Wenxia Chen
Xianyu Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1606716

3,657 views
1 citation

Original Research

Published on 23 Jul 2025

Association of gastroesophageal reflux disease with the incidence of pulmonary disease

in Molecular and Cellular Pathology

Xin Wang
Yan Wang
Yijie Bu
Yu Liu
Sheng Gong
Guowei Che

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1552126

5,199 views
1 citation

Editorial

Published on 23 Jul 2025

Editorial: Current trends in muscle diseases and their treatment strategies

in Molecular and Cellular Pathology

Zihang Guo
Shoulong Deng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1660074

2,061 views

Original Research

Published on 23 Jul 2025

Multimodal reasoning agent for enhanced ophthalmic decision-making: a preliminary real-world clinical validation

in Molecular and Cellular Pathology

Yijing Zhuang
Dong Fang
Pengfeng Li
Bingyu Bai
Xiangqing Hei
Lujia Feng
Wangting Li
Shaochong Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1642539

2,878 views
1 citation

Review

Published on 22 Jul 2025

Characteristics and advances in signaling pathways, cellular communication, cell junctions, and oxidative stress in lymphedema

in Molecular and Cellular Pathology

Qiancheng Zhao
Zhipu Niu
Ying Pan
Yongqi Hao
Yuan Ma
Jiankai Zhao
Jianshi Du
Yiming Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1521320

3,358 views
1 citation

Review

Published on 21 Jul 2025

Dynamic crosstalk between HSCs and liver microenvironment: multicellular interactions in the regulation of liver fibrosis

in Molecular and Cellular Pathology

Luping Wang
Yi Huang
Jingrong Chen
Jialu Gao
Sihan Chen
Mingqi Zhao
Jiguo Lin
Shunqing Zhou
Yannan Shen
Yunyun Cheng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1635763

3,979 views
2 citations

Methods

Published on 18 Jul 2025

Optimizing chromosome dispersion quality: the key role of cell density

in Molecular and Cellular Pathology

Chao-Xian Gao
Li-Mei Li
Yu-Ting Chen
Ying-Yan Guo
Bo-Xin Li
Xue-Qin Yang
Chang-Ye Hui

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1636498

1,719 views

Review

Published on 18 Jul 2025

miRNAs and exosomes in psoriasis: coordinating cytoskeleton dynamics and extracellular matrix remodeling

in Molecular and Cellular Pathology

Sijing Li
Zamri Chik
Farid Nazer Faruqu
Najihah Mohd Hashim
Nor Saadah Mohd Yusof
Jennifer Fernandez Alarcon
Noraini Ahmad

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608902

3,078 views
1 citation

Original Research

Published on 17 Jul 2025

Deep learning-based classification of multiple fundus diseases using ultra-widefield images

in Molecular and Cellular Pathology

Ming-Ming Duan
Xiang Tu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1630667

3,330 views
2 citations

Original Research

Published on 17 Jul 2025

Profiling the impact of different tau species on glial cell biology

in Molecular and Cellular Pathology

Ines Arribas Gomez
Yan Yan
Meredith T. Lilley
Yunfei Chen
Lillian M. Daughrity
Ana Moreno Arnas
Ji Shi
Jennifer M. Kachergus
E. Aubrey Thompson
Karen Jansen-West

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1622138

2,679 views

Original Research

Published on 17 Jul 2025

Standardized conversion model for retinal thickness measurements between spectral-domain and swept-source optical coherence tomography based on machine learning

in Molecular and Cellular Pathology

Zhongping Tian
Yinning Guo
Xi Chen
Qifeng Zhou
Yuan Liu
Zhizhu Yi
Li Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1612455

1,548 views

2,488 articles

articles

Integrated single-cell and bulk transcriptome analysis reveal lactate metabolism-related signature and T cell alteration in atrial fibrillation

Fufang Duzhong Jiangu granule (FFDZ) ameliorates osteoarthritis development through maintaining subchondral bone homeostasis

Matrisome remodeling in the myocardium of hypertrophic cardiomyopathy; novel targets for molecular diagnostics

Research progress in deep learning-based fundus image analysis for the diagnosis and prediction of hypertension-related diseases

A new digital biomarker of Demodex blepharitis: energy curve of the meibomian edge

The neural signature of high myopia: structural and functional brain alterations and their cognitive-emotional associations

Advances in cfDNA research for pregnancy-related diseases

Predicting visual acuity of treated ocular trauma based on pattern visual evoked potentials by machine learning models

Beyond vision loss: the impact of glaucoma on the brain

Molecular signatures of preeclampsia subtypes determined through integrated weighted gene co-expression network analysis and differential gene expression analysis of placental transcriptomics

Editorial: Lymphatic system: organ specific functions in health and disease, volume II

Altered endoplasmic reticulum calcium loading in human PLN-R14del cardiomyopathy

Automated detection of diabetic retinopathy lesions in ultra-widefield fundus images using an attention-augmented YOLOv8 framework

Saliva-derived exosomes regulate fibroblast metabolic reprogramming in skin wound healing

Association of gastroesophageal reflux disease with the incidence of pulmonary disease

Editorial: Current trends in muscle diseases and their treatment strategies

Multimodal reasoning agent for enhanced ophthalmic decision-making: a preliminary real-world clinical validation

Characteristics and advances in signaling pathways, cellular communication, cell junctions, and oxidative stress in lymphedema

Dynamic crosstalk between HSCs and liver microenvironment: multicellular interactions in the regulation of liver fibrosis

Optimizing chromosome dispersion quality: the key role of cell density

miRNAs and exosomes in psoriasis: coordinating cytoskeleton dynamics and extracellular matrix remodeling

Deep learning-based classification of multiple fundus diseases using ultra-widefield images

Profiling the impact of different tau species on glial cell biology

Standardized conversion model for retinal thickness measurements between spectral-domain and swept-source optical coherence tomography based on machine learning