Frontiers in Cell and Developmental Biology | Molecular and Cellular Pathology

Original Research

Published on 16 Jun 2025

Deep learning system for the auxiliary diagnosis of thyroid eye disease: evaluation of ocular inflammation, eyelid retraction, and eye movement disorder

in Molecular and Cellular Pathology

Yu Han
Jun Xie
Xiaoyu Li
Xinying Xu
Bin Sun
Han Liu
Chunfang Yan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609231

2,476 views

Review

Published on 13 Jun 2025

Mitochondrial metabolic regulation of macrophage polarization in osteomyelitis and other orthopedic disorders: mechanisms and therapeutic opportunities

in Molecular and Cellular Pathology

Jinglin Li
Lin Zhang
Jiaze Peng
Chuntao Zhao
Wenguang Li
Yang Yu
Xianpeng Huang
Fuyin Yang
Xuan Deng
Xuxu Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1604320

4,255 views
3 citations

Review

Published on 10 Jun 2025

Genetic landscape of phospholamban cardiomyopathies

in Molecular and Cellular Pathology

Elizabeth Vafiadaki
Ishita Chaudhari
Keisha Mireia Soliman
Aristides G. Eliopoulos
Evangelia G. Kranias
Despina Sanoudou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1626242

3,706 views
1 citation

Original Research

Published on 10 Jun 2025

Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging

in Molecular and Cellular Pathology

Iuliia Golovynska
Qinglin Chen
Yurii V. Stepanov
Danying Lin
Junle Qu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1610204

3,116 views
2 citations

Review

Published on 09 Jun 2025

Vesicular trafficking and cell-cell communication in neurodevelopment and neurodegeneration

in Molecular and Cellular Pathology

Salma Amin
Elena Taverna

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1600034

5,497 views
4 citations

Original Research

Published on 06 Jun 2025

MSLI-Net: retinal disease detection network based on multi-segment localization and multi-scale interaction

in Molecular and Cellular Pathology

Zhenjia Qi
Jin Hong
Jilan Cheng
Guoli Long
Hanyu Wang
Siyue Li
Shuangliang Cao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608325

3,280 views
3 citations

Original Research

Published on 06 Jun 2025

17β-estradiol maintains extracellular matrix homeostasis of nucleus pulposus cells by activating p70 S6K1 signaling pathway

in Molecular and Cellular Pathology

Tao Liu
Zhaohui Li
Wei Zhang
Xuzhao Guo
Guobin Liu
Dalong Yang
Sidong Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564458

2,634 views

Review

Published on 05 Jun 2025

Immune dysregulation in ulcerative colitis: pathogenic mechanisms and therapeutic strategies of traditional Chinese medicine

in Molecular and Cellular Pathology

Xudong Tang
Yilin Huang
Ying Zhu
Yin Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1610435

8,836 views
10 citations

Original Research

Published on 04 Jun 2025

Assessment of synthetic post-therapeutic OCT images using the generative adversarial network in patients with macular edema secondary to retinal vein occlusion

in Molecular and Cellular Pathology

Shi Feng
Jingyuan Yang
Xinyu Zhao
Jianchun Zhao
Yunfeng Du
Weihong Yu
Dayong Ding
Xirong Li
Youxin Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609567

2,198 views
1 citation

Original Research

Published on 03 Jun 2025

Assessment of retinal and choroidal microcirculatory alterations following radiofrequency catheter ablation in atrial fibrillation patients using swept-source optical coherence tomography angiography

in Molecular and Cellular Pathology

Jin Wang
Huiran Yang
Qingjian Li
Yucen Wang
Pei Zhang
Zhiliang Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1612303

2,172 views
1 citation

Review

Published on 03 Jun 2025

Chronotherapy and intervertebral disc degeneration: understanding the role of circadian rhythm in degenerative processes

in Molecular and Cellular Pathology

Cong Zhang
Rende Zhang
Guanghai Zhao
Zuolong Wu
Wei Song
Rui Ran
Kaisheng Zhou
Haihong Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1586193

4,445 views
2 citations

Original Research

Published on 30 May 2025

Automatic detection of optic canal fractures and recognition and segmentation of anatomical structures in the orbital apex based on artificial intelligence

in Molecular and Cellular Pathology

Yu-Lin Li
Yu-Hao Li
Mu-Yang Wei
Guang-Yu Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609028

2,106 views

Mini Review

Published on 30 May 2025

Exercise benefits yourself and your offspring: a mini-review

in Molecular and Cellular Pathology

Kun Wang
Jiajia Zhao
Yanqiu Wang
Mairu Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1606790

4,524 views
1 citation

Original Research

Published on 30 May 2025

A machine learning model for predicting anatomical response to Anti-VEGF therapy in diabetic macular edema

in Molecular and Cellular Pathology

Wenrui Lu
Kunhong Xiao
Xuemei Zhang
Yuqing Wang
Wenbin Chen
Xierong Wang
Yunxi Ye
Yan Lou
Li Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1603958

3,407 views
4 citations

Review

Published on 30 May 2025

Deep learning-driven approach for cataract management: towards precise identification and predictive analytics

in Molecular and Cellular Pathology

Shuaixin Lu
Lingling Ba
Jie Wang
Min Zhou
Peiyao Huang
Xiaohua Zhang
Simo Pan
Xinmiao Zhou
Kai Wen
Jing Sun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1611216

4,288 views
2 citations

Review

Published on 29 May 2025

A comprehensive overview of focused ion beam-scanning electron microscopy (FIB-SEM) applications for the evaluation of outer retina

in Molecular and Cellular Pathology

Sanjay Ch
Rayne R. Lim
Shermaine W. Y. Low
Deana G. Grant
Sam Patterson
Aparna Ramasubramanian
Ashish K. Gadicherla
Shyam S. Chaurasia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1586029

4,705 views
1 citation

Editorial

Published on 29 May 2025

Editorial: Next generation micro-physiological systems for pragmatic use in regular industrial workflow

in Molecular and Cellular Pathology

Ali Kermanizadeh
David M. Brown
Wolfgang Moritz

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1607979

4,371 views

Original Research

Published on 26 May 2025

Early detection of retinal and choroidal microvascular impairments in diabetic patients with myopia

in Molecular and Cellular Pathology

Yufei Wu
Jiahui Jiang
Xiaoyu Deng
Xixi Zhang
Jinger Lu
Zian Xu
Yitian Zhao
Zai-Long Chi
Qinkang Lu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609928

3,003 views
4 citations

Original Research

Published on 23 May 2025

Large language model-based multimodal system for detecting and grading ocular surface diseases from smartphone images

in Molecular and Cellular Pathology

Zhongwen Li
Zhouqian Wang
Liheng Xiu
Pengyao Zhang
Wenfang Wang
Yangyang Wang
Gang Chen
Weihua Yang
Wei Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1600202

3,342 views
7 citations

Original Research

Published on 22 May 2025

snRNA-seq reveals subcutaneous white adipose tissue remodeling upon return to thermoneutrality after cold stimulation

in Molecular and Cellular Pathology

Yusha Yang
Guanyu Zhang
Ting Yi
Shuran Yang
Shuai Wu
Yongqiang Zhang
Li Zhang
Xi Li
Xiuxuan Wu
Jun Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1578180

3,242 views
2 citations

Original Research

Published on 22 May 2025

Machine learning-driven prediction of cycloplegic refractive error in Chinese children

in Molecular and Cellular Pathology

Bichi Chen
Li Tian
Fuyue Tian
Qiaochu Yang
Ying Ruan
Ying Li
Min Cao
Chuanyan Wu
Maoyuan Yang
Suzhong Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608494

1,982 views
1 citation

Original Research

Published on 22 May 2025

Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors

in Molecular and Cellular Pathology

Carly R. Cabel
Briana A. Guzman
Elaheh Alizadeh
Shuaizhi Li
Cameron Holberg
Chonlarat Wichaidit
Darren A. Cusanovich
Andrew L. Paek
Gregory R. J. Thatcher
Koenraad Van Doorslaer

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1538934

2,998 views

Original Research

Published on 22 May 2025

Integration of machine learning and bulk sequencing revealed exosome-related gene FOSB was involved in the progression of abdominal aortic aneurysm

in Molecular and Cellular Pathology

Xianlu Ma
Hongjie Zhou
Ren Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1554972

2,920 views

Original Research

Published on 21 May 2025

Based on TransRes-Pix2Pix network to generate the OBL image during SMILE surgery

in Molecular and Cellular Pathology

Zeyu Zhu
Peifen Lin
Lingling Zhong
Qing Wang
Jingjing Xu
Kang Yu
Zheliang Guo
Yicheng Xu
Taorong Qiu
Yifeng Yu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1598475

2,394 views

2,492 articles

articles

Deep learning system for the auxiliary diagnosis of thyroid eye disease: evaluation of ocular inflammation, eyelid retraction, and eye movement disorder

Mitochondrial metabolic regulation of macrophage polarization in osteomyelitis and other orthopedic disorders: mechanisms and therapeutic opportunities

Genetic landscape of phospholamban cardiomyopathies

Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging

Vesicular trafficking and cell-cell communication in neurodevelopment and neurodegeneration

MSLI-Net: retinal disease detection network based on multi-segment localization and multi-scale interaction

17β-estradiol maintains extracellular matrix homeostasis of nucleus pulposus cells by activating p70 S6K1 signaling pathway

Immune dysregulation in ulcerative colitis: pathogenic mechanisms and therapeutic strategies of traditional Chinese medicine

Assessment of synthetic post-therapeutic OCT images using the generative adversarial network in patients with macular edema secondary to retinal vein occlusion

Assessment of retinal and choroidal microcirculatory alterations following radiofrequency catheter ablation in atrial fibrillation patients using swept-source optical coherence tomography angiography

Chronotherapy and intervertebral disc degeneration: understanding the role of circadian rhythm in degenerative processes

Automatic detection of optic canal fractures and recognition and segmentation of anatomical structures in the orbital apex based on artificial intelligence

Exercise benefits yourself and your offspring: a mini-review

A machine learning model for predicting anatomical response to Anti-VEGF therapy in diabetic macular edema

Deep learning-driven approach for cataract management: towards precise identification and predictive analytics

A comprehensive overview of focused ion beam-scanning electron microscopy (FIB-SEM) applications for the evaluation of outer retina

Editorial: Next generation micro-physiological systems for pragmatic use in regular industrial workflow

Early detection of retinal and choroidal microvascular impairments in diabetic patients with myopia

Large language model-based multimodal system for detecting and grading ocular surface diseases from smartphone images

snRNA-seq reveals subcutaneous white adipose tissue remodeling upon return to thermoneutrality after cold stimulation

Machine learning-driven prediction of cycloplegic refractive error in Chinese children

Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors

Integration of machine learning and bulk sequencing revealed exosome-related gene FOSB was involved in the progression of abdominal aortic aneurysm

Based on TransRes-Pix2Pix network to generate the OBL image during SMILE surgery