Frontiers in Cell and Developmental Biology | Molecular and Cellular Reproduction

Review

Published on 01 Oct 2025

From biomolecules to breakthroughs: exosomes as next-generation theranostics in female infertility

in Molecular and Cellular Reproduction

Ahmed A. Aldarmahi
Shifan Khanday
Ehab S. Taher
Ahmed Abdeen
Gamal A. Atia
Dania A. Mohammed
Dina S. Nasr
Rayan G. Albarakati
Donia E. Zaghamir
Helal F. Hetta

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1605174

7,913 views

Mini Review

Published on 23 Sep 2025

Metabolic state and female fertility in ART cycles: a summary of current advances

in Molecular and Cellular Reproduction

Natascha Berger
Katharina Brugger
Herbert Fluhr

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1645127

2,727 views
1 citation

Review

Published on 22 Sep 2025

Cracking the code: how piRNA pathway shapes spermatogenesis and combats male infertility

in Molecular and Cellular Reproduction

Zhidan Hong
Sihan Huang
Li Li
Ying Gao
Binyu Ma
Qigang Fan
Yuanzhen Zhang
Mei Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1657744

4,071 views
2 citations

Editorial

Published on 01 Sep 2025

Editorial: Sperm epigenetic code: implications in reproductive health and paternal contribution to embryo development

in Molecular and Cellular Reproduction

Marta Lombò
Gilda Cobellis
Francesco Manfrevola

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1666435

1,866 views

Original Research

Published on 29 Aug 2025

Integrating microarray data and single-cell RNA-seq reveals correlation between kit and nmyc in mouse spermatogonia stem cell population

in Molecular and Cellular Reproduction

Danial Hashemi Karoii
Hossein Azizi
Thomas Skutella

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1634347

3,591 views
4 citations

Review

Published on 29 Aug 2025

Exploring the protective effects of coenzyme Q10 on female fertility

in Molecular and Cellular Reproduction

Yu Jiang
Yao Han
Pengyun Qiao
Fa Ren

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1633166

16,254 views

Original Research

Published on 29 Aug 2025

High-glucose diets differentially modulate phosphatidylcholine metabolism and fecundity in Caenorhabditis elegans

in Molecular and Cellular Reproduction

Chao-Wen Wang
Phebe Chiu
Sophia Monsalve
Ricardo Roure
Xiaofei Bai
Jia-Jin Law
Yu-Ching Wu
Yet-Ran Chen
You-Liang Cheng
Rey-Huei Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1622695

3,257 views

Original Research

Published on 29 Aug 2025

SIRT1 retention in elongating spermatids interferes with histone displacement by counteracting MOF-dependent H4K16 acetylation

in Molecular and Cellular Reproduction

Veronica Porreca
Teresa Chioccarelli
Francesco Albano
Valeria Nittoli
Giulia Ricci
Concetta Ambrosino
Rosanna Chianese
Vincenza Grazia Mele
Antonella Migliaccio
Mariano Stornaiuolo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1524919

2,083 views
1 citation

Review

Published on 22 Aug 2025

The role of amniotic epithelial cells in preterm birth: mechanisms and clinical implications

in Molecular and Cellular Reproduction

Lulu Meng
Jing Yang
Yijie Gao
Yiran Xie
Miaomiao Chen
Wangping Hao
Yi Luo
Ping Ru
Ling Wang
Zhiying He

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1590212

2,528 views
1 citation

Review

Published on 22 Aug 2025

Microbial metabolites short chain fatty acids, tight junction, gap junction, and reproduction: a review

in Molecular and Cellular Reproduction

Lulu Fu
Min Wang
Dan Li
Shuai Ma
Fuliang Zhang
Lianwen Zheng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1624415

4,183 views
4 citations

Original Research

Published on 18 Aug 2025

Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone

in Molecular and Cellular Reproduction

Zetong Zheng
Jifan Tan
Minghui Chen
Xiubing Zhang
Simin Liu
Yangxing Wen
Lingli Long
Canquan Zhou
Yubin Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1647476

2,001 views

Original Research

Published on 08 Aug 2025

MRE11 orchestrates porcine oocyte meiotic progression by modulating the spindle assembly checkpoint

in Molecular and Cellular Reproduction

Dandan Zhang
Zaishan Yang
Yongteng Zhang
Fugui Fang
Hongguo Cao
Yunsheng Li
Zubing Cao
Yanfeng Xue
Mianqun Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1635110

1,886 views

Original Research

Published on 04 Aug 2025

Spatial transcriptomics reveals Inhba/Smad2/E2f4 axis in Lrp2high thecal cell proliferation in androgen-induced PCOS mice

in Molecular and Cellular Reproduction

Man Luo
Xiaona Tian
Li Li
Guomei Zhang
Wenzhi Liu
Linlin Mei
Haoran Li
Xiaoyan You
Dongmei Zhang
Mengsi Zhou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1633254

3,188 views

Review

Published on 28 Jul 2025

Stage-specific autophagy dynamics in reproductive processes and associated disorders

in Molecular and Cellular Reproduction

Jiayi Wang
Shuo Tu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1639691

2,200 views
1 citation

Original Research

Published on 24 Jul 2025

Extracellular vesicles as prospective biological indicators for midgestational placental complications in the mouse

in Molecular and Cellular Reproduction

Elaine Lee
Parinaz Kazemi
Shiva Shafiei
Sarah Yull
Mansuba Rana
Nadim Tawil
Laura Montermini
Janusz Rak
Daniel Dufort

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1636335

3,007 views
1 citation

Original Research

Published on 11 Jul 2025

Activation of telomerase via madecassic acid enhances the developmental competence of the SCNT-derived bovine embryos

in Molecular and Cellular Reproduction

Zaheer Haider
Safeer Ullah
Tahir Muhammad
Chalani Dilshani Perera
Muhammad Tayyab Khan
Asif Jan
Seung-Eun Lee
Seo-Hyun Lee
Sung Woo Kim
Muhammad Idrees

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1628953

4,029 views
1 citation

Original Research

Published on 01 Jul 2025

ELK1 regulates BMPR1B transcriptional activity in ovine granulosa cells

in Molecular and Cellular Reproduction

Anwar Abdurahman
Yuling Ga
Xuehai Ma

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1623135

1,789 views
2 citations

Mini Review

Published on 26 Jun 2025

Oocyte and dietary supplements: a mini review

in Molecular and Cellular Reproduction

Hao Chen
Shuoqi Wang
Meiying Song
Dongxia Yang
Hongmei Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1619758

6,780 views
6 citations

Original Research

Published on 25 Jun 2025

Investigating SMYD3 role during oocyte maturation in a 3D follicle-enclosed oocyte in vitro model in sheep

in Molecular and Cellular Reproduction

Chiara Camerano Spelta Rapini
Alessia Peserico
Chiara Di Berardino
Giulia Capacchietti
Camila Rojo-Fleming
Andrada-Ioana Damian-Buda
Irem Unalan
Aldo Roberto Boccaccini
Valentina Grossi
Mauro Mattioli

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1625914

2,052 views

Original Research

Published on 16 Jun 2025

Mitochonic acid 5 increases boar sperm quality by mitigating mitochondrial dysfunction

in Molecular and Cellular Reproduction

Ruyuan Wang
Adedeji O. Adetunji
Lingjiang Min
Zhendong Zhu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1583951

2,258 views
2 citations

Original Research

Published on 10 Jun 2025

Mitochondrial morphology in fertile and infertile men: image processing and morphometric analysis of the sperm midpiece

in Molecular and Cellular Reproduction

María Fernanda Skowronek
Santiago Pietroroia
Gabriel de Cola
Mauricio Ramos
Diego Silvera
Gabriela Casanova
Federico Lecumberry
Adriana Cassina
Rossana Sapiro

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609081

3,473 views
2 citations

Review

Published on 09 Jun 2025

Ferroptosis and recurrent miscarriage: a critical review of pathophysiology and emerging therapeutic targets

in Molecular and Cellular Reproduction

Mohammad Masoud Khodaei
Zahra Noori
Fateme Zare
Ahmad Meshkin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1559300

4,391 views
5 citations

Original Research

Published on 02 Jun 2025

Myosin VI is expressed in developing ovarian follicles in Drosophila but is not essential for effective oogenesis

in Molecular and Cellular Reproduction

Robert Lenartowski
Jakub Ostrowski
Anna Suwińska
Anna Richert
Przemysław Zakrzewski
Magdalena Izdebska
Wioletta Arendt
Kathryn G. Miller
Marta Lenartowska

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1535117

3,195 views

Original Research

Published on 02 Jun 2025

Gonadotropins differentially regulate testicular cell adhesion and junctional complexes during flatfish spermiogenesis through the oxytocin and relaxin signaling pathways

in Molecular and Cellular Reproduction

Noelia López-Fortún
Jose Vicente Roig-Genovés
Ignacio Giménez
Joan Cerdà
François Chauvigné

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1574690

2,489 views
3 citations

388 articles

articles

From biomolecules to breakthroughs: exosomes as next-generation theranostics in female infertility

Metabolic state and female fertility in ART cycles: a summary of current advances

Cracking the code: how piRNA pathway shapes spermatogenesis and combats male infertility

Editorial: Sperm epigenetic code: implications in reproductive health and paternal contribution to embryo development

Integrating microarray data and single-cell RNA-seq reveals correlation between kit and nmyc in mouse spermatogonia stem cell population

Exploring the protective effects of coenzyme Q10 on female fertility

High-glucose diets differentially modulate phosphatidylcholine metabolism and fecundity in Caenorhabditis elegans

SIRT1 retention in elongating spermatids interferes with histone displacement by counteracting MOF-dependent H4K16 acetylation

The role of amniotic epithelial cells in preterm birth: mechanisms and clinical implications

Microbial metabolites short chain fatty acids, tight junction, gap junction, and reproduction: a review

Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone

MRE11 orchestrates porcine oocyte meiotic progression by modulating the spindle assembly checkpoint

Spatial transcriptomics reveals Inhba/Smad2/E2f4 axis in Lrp2high thecal cell proliferation in androgen-induced PCOS mice

Stage-specific autophagy dynamics in reproductive processes and associated disorders

Extracellular vesicles as prospective biological indicators for midgestational placental complications in the mouse

Activation of telomerase via madecassic acid enhances the developmental competence of the SCNT-derived bovine embryos

ELK1 regulates BMPR1B transcriptional activity in ovine granulosa cells

Oocyte and dietary supplements: a mini review

Investigating SMYD3 role during oocyte maturation in a 3D follicle-enclosed oocyte in vitro model in sheep

Mitochonic acid 5 increases boar sperm quality by mitigating mitochondrial dysfunction

Mitochondrial morphology in fertile and infertile men: image processing and morphometric analysis of the sperm midpiece

Ferroptosis and recurrent miscarriage: a critical review of pathophysiology and emerging therapeutic targets

Myosin VI is expressed in developing ovarian follicles in Drosophila but is not essential for effective oogenesis

Gonadotropins differentially regulate testicular cell adhesion and junctional complexes during flatfish spermiogenesis through the oxytocin and relaxin signaling pathways