Frontiers in Cell and Developmental Biology

Review

Published on 15 Aug 2025

The role of gut microbiota dysbiosis in drug-induced brain injury: mechanisms and therapeutic implications

in Signaling

Jinghui Zhai
Yue Zhang
Shuyue Ma
Yingli Zhang
Miao Jin
Huiyu Yan
Sixi Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1604539

324 views

Opinion

Published on 15 Aug 2025

RAC1 signaling in prostate cancer: VAV GEFs take center stage

in Signaling

Mariana Cooke
Nahuel Peinetti
Marcelo G. Kazanietz
Kerry L. Burnstein

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1658639

326 views

Review

Accepted on 13 Aug 2025

The multifaceted roles of E3 ubiquitin ligases in osteoarthritis

in Signaling

Zheng Jin
Zhenhua Zhu
Jun Chen
Xiaopeng Jing
Jie Tan
Ji Zeng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1665313

105 views

Editorial

Published on 12 Aug 2025

Editorial: Deciphering signaling pathway interactions in tissue homeostasis

in Signaling

John T. Hancock

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1677790

216 views

Original Research

Published on 12 Aug 2025

The lncRNA Jpx participates in testosterone-induced H9c2 cell hypertrophy by targeting the miR-145-5p/Nfatc3 axis

in Signaling

Mingxing Wen
Xinyu Zhang
Litao Tong
Yuhui Chen
Zhengjie Li
Yichen Wang
Can Liu
Jinwei Zhang
Liangpeng Ge
Jing Sun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1620369

321 views

Correction

Published on 08 Aug 2025

Correction: KRAS and NRF2 drive metabolic reprogramming in pancreatic cancer cells: the influence of oxidative and nitrosative stress

in Signaling

Valentina Rapozzi
Clara Comuzzi
Eros Di Giorgio
Luigi E. Xodo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1661525

232 views

Review

Published on 08 Aug 2025

The multifaceted impact of physical exercise on FoxO signaling pathways

in Signaling

Wei Liu
Pengjun Meng
Zhi Li
Yifei Shen
Xin Meng
Shen Jin
Mengdi Hu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1614732

381 views

Original Research

Published on 07 Aug 2025

Protective effects of paederoside in rotenone-induced cellular models of Parkinson’s disease

in Signaling

Juan Lang
Zhongkui Xiong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1631652

331 views

Review

Accepted on 06 Aug 2025

Critical Signaling Pathways in Osteoclast Differentiation and Bone Resorption: Mechanisms and Therapeutic Implications for Periprosthetic Osteolysis Type of the Study: Review Articles

in Signaling

Liangzi Yin
Chenglin Sun
Junjie Zhang
Yan Li
Yansheng Wang
Lunhao Bai
Zeming Lei

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1639430

133 views

Original Research

Published on 05 Aug 2025

Epigenetic regulation of the respiratory chain by a mitochondrial distress-related redox signal

in Signaling

Marius W. Baeken
Ankush Borlepawar
Philipp Kötzner
Holger Richly
Christian Behl
Bernd Moosmann
Parvana Hajieva

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608400

1,082 views

Original Research

Accepted on 30 Jul 2025

Slit2 inhibits SRC-PI3K signaling pathway, regulates osteoclast differentiation of macrophages and reduces bone resorption

in Signaling

Qing Ge
Yaokun Zou
Huizhi Deng
Zhe Yang
Linhu Ge
Jieying Huang
Liping Wang
Jianqiang Cai

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1632882

173 views

Original Research

Accepted on 26 Jul 2025

Endogenous ligands of bovine FFAR2/GPR43 display distinct pharmacological properties

in Signaling

Tainara Cristina Michelotti
Valérie Lamothe
Frederic Jean-Alphonse
Eric Reiter
Muriel Bonnet
Guillaume Durand

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1645031

250 views

Original Research

Published on 24 Jul 2025

TRABD maintains mitochondrial homeostasis and protects against ischemia reperfusion-induced renal tubular injury

in Signaling

Wenqi Duan
Wenye Wu
Cui Yang
Mei Zhang
Xuemei Li
Wenmin Tian
Yang Chen
Xinjun Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1619339

864 views

Editorial

Published on 18 Jul 2025

Editorial: Neuronal guidance signaling in health and neurological diseases

in Signaling

Satoru Yamagishi
Masaki Hiramoto
Junichi Yuasa-Kawada

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1661836

573 views

Brief Research Report

Published on 16 Jul 2025

The β-adrenergic receptor-SGK1 signaling pathway in brown adipocytes protects GOT1 from proteasomal degradation

in Signaling

Chul-Hong Park
Minsung Park
J. Jason Collier
Ji Suk Chang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1637770

860 views

Review

Published on 10 Jul 2025

Mechanosensitive Piezo channels in mineralized tissues: emerging roles in osteodental adaptation and disease

in Signaling

Junchi Dong
Ran Li
Yuhuang Chen
Guixin Zhu
Xing Liang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1607337

1,155 views