Frontiers in Cell and Developmental Biology

Original Research

Published on 30 Sep 2021

Global SUMOylome Adjustments in Basal Defenses of Arabidopsis thaliana Involve Complex Interplay Between SMALL-UBIQUITIN LIKE MODIFIERs and the Negative Immune Regulator SUPPRESSOR OF rps4-RLD1

in Signaling

Mritunjay Kasera
Kishor D. Ingole
Sakshi Rampuria
Yashika Walia
Walter Gassmann
Saikat Bhattacharjee

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.680760

4,745 views

Brief Research Report

Published on 30 Sep 2021

SUMOylation of Arginyl tRNA Synthetase Modulates the Drosophila Innate Immune Response

in Signaling

Prajna Nayak
Aarti Kejriwal
Girish S. Ratnaparkhi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.695630

4,146 views
1 citation

Original Research

Published on 29 Sep 2021

Obesity Inhibits Angiogenesis Through TWIST1-SLIT2 Signaling

in Signaling

Tendai Hunyenyiwa
Kathryn Hendee
Kienna Matus
Priscilla Kyi
Tadanori Mammoto
Akiko Mammoto

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.693410

5,664 views
26 citations

Original Research

Published on 29 Sep 2021

Development and Validation of an IL6/JAK/STAT3-Related Gene Signature to Predict Overall Survival in Clear Cell Renal Cell Carcinoma

in Signaling

Chuanchuan Zhan
Chao Xu
Jiajun Chen
Chong Shen
Jinkun Li
Zichu Wang
Xiangrong Ying
Zhengang Luo
Yu Ren
Gangfeng Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.686907

3,931 views
17 citations

Review

Published on 29 Sep 2021

Distinct Identity of GLP-1R, GLP-2R, and GIPR Expressing Cells and Signaling Circuits Within the Gastrointestinal Tract

in Signaling

Nadya M. Morrow
Antonio A. Hanson
Erin E. Mulvihill

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.703966

13,995 views
12 citations

Original Research

Published on 28 Sep 2021

Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro

in Signaling

Yifan Xia
Yunfei Li
Wasem Khalid
Marom Bikson
Bingmei M. Fu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.731028

7,404 views
17 citations

Editorial

Published on 27 Sep 2021

Editorial: Emerging Mechanisms for Skeletal Muscle Mass Regulation

in Signaling

Yuji Ogura
Shuichi Sato
Yann S. Gallot
Susan Tsivitse Arthur

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.764095

2,111 views

Original Research

Published on 24 Sep 2021

Lgr4 Regulates Oviductal Epithelial Secretion Through the WNT Signaling Pathway

in Signaling

Xue Tan
Lingling Zhang
Tianqi Li
Jianmin Zhan
Kun Qiao
Haili Wu
Shenfei Sun
Meina Huang
Fangxi Zhang
Meixing Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.666303

4,551 views
9 citations

Original Research

Published on 24 Sep 2021

An Adipose-Derived Injectable Sustained-Release Collagen Scaffold of Adipokines Prepared Through a Fast Mechanical Processing Technique for Preventing Skin Photoaging in Mice

in Signaling

Xiaoxuan Jin
Yuchen Zhang
Xiangdong Zhang
Yibao Li
Mimi Xu
Kaiyang Liu
Jiangjiang Ru
Chijuan Ma
Yao Yao
Yunfan He

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.722427

6,436 views
11 citations

Original Research

Published on 23 Sep 2021

Single-Molecule Imaging Reveals Rapid Estradiol Action on the Surface Movement of AMPA Receptors in Live Neurons

in Signaling

Soma Godó
Klaudia Barabás
Ferenc Lengyel
Dávid Ernszt
Tamás Kovács
Miklós Kecskés
Csaba Varga
Tibor Z. Jánosi
Géza Makkai
Gergely Kovács

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.708715

4,640 views
3 citations

Review

Published on 23 Sep 2021

Organoid Technology: A Reliable Developmental Biology Tool for Organ-Specific Nanotoxicity Evaluation

in Signaling

Minakshi Prasad
Rajesh Kumar
Lukumoni Buragohain
Ankur Kumari
Mayukh Ghosh

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.696668

14,744 views
53 citations

Review

Published on 23 Sep 2021

Folding Mitochondrial-Mediated Cytosolic Proteostasis Into the Mitochondrial Unfolded Protein Response

in Signaling

Edmund Charles Jenkins
Mrittika Chattopadhyay
Doris Germain

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.715923

6,685 views
13 citations

Original Research

Published on 23 Sep 2021

Thrombospondin-4 Is a Soluble Dermal Inflammatory Signal That Selectively Promotes Fibroblast Migration and Keratinocyte Proliferation for Skin Regeneration and Wound Healing

in Signaling

Mariliis Klaas
Kristina Mäemets-Allas
Elizabeth Heinmäe
Heli Lagus
Claudia Griselda Cárdenas-León
Terje Arak
Mart Eller
Külli Kingo
Esko Kankuri
Viljar Jaks

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.745637

9,502 views
31 citations

Brief Research Report

Published on 23 Sep 2021

Dermatan-4-O-Sulfotransferase-1 Contributes to the Undifferentiated State of Mouse Embryonic Stem Cells

in Signaling

Chika Ogura
Shoko Nishihara

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.733964

3,351 views
7 citations

Review

Published on 21 Sep 2021

Beyond Neurons: Long Distance Communication in Development and Cancer

in Signaling

Patrick McMillen
Madeleine J. Oudin
Michael Levin
Samantha L. Payne

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.739024

17,263 views
30 citations

Original Research

Published on 21 Sep 2021

SALL1 Modulates CBX4 Stability, Nuclear Bodies, and Regulation of Target Genes

in Signaling

Immacolata Giordano
Lucia Pirone
Veronica Muratore
Eukene Landaluze
Coralia Pérez
Valerie Lang
Elisa Garde-Lapido
Monika Gonzalez-Lopez
Orhi Barroso-Gomila
Alfred C. O. Vertegaal

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.715868

5,212 views
4 citations

Original Research

Published on 21 Sep 2021

Human Three-Finger Protein Lypd6 Is a Negative Modulator of the Cholinergic System in the Brain

in Signaling

Dmitrii Kulbatskii
Zakhar Shenkarev
Maxim Bychkov
Eugene Loktyushov
Mikhail Shulepko
Sergey Koshelev
Igor Povarov
Alexander Popov
Steve Peigneur
Anton Chugunov

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.662227

7,169 views
19 citations

Original Research

Published on 21 Sep 2021

Direct Evidence of Endothelial Dysfunction and Glycocalyx Loss in Dermal Biopsies of Patients With Chronic Kidney Disease and Their Association With Markers of Volume Overload

in Signaling

Josephine Koch
Ryanne S. Hijmans
Manuela Ossa Builes
Wendy A. Dam
Robert A. Pol
Stephan J. L. Bakker
Hendri H. Pas
Casper F. M. Franssen
Jacob van den Born

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.733015

3,815 views
3 citations

Original Research

Published on 20 Sep 2021

Mitochondrial Impairment by MitoBloCK-6 Inhibits Liver Cancer Cell Proliferation

in Signaling

Yaschar Kabiri
Anna Fuhrmann
Anna Becker
Luisa Jedermann
Carola Eberhagen
Ann-Christine König
Tiago Barros Silva
Fernanda Borges
Stefanie M. Hauck
Bernhard Michalke

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.725474

5,082 views
5 citations

Original Research

Published on 20 Sep 2021

Galectin-3 Enhances Vascular Endothelial Growth Factor-A Receptor 2 Activity in the Presence of Vascular Endothelial Growth Factor

in Signaling

Issahy Cano
Zhengping Hu
Dina B. AbuSamra
Magali Saint-Geniez
Yin Shan Eric Ng
Pablo Argüeso
Patricia A. D’Amore

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.734346

5,550 views
13 citations

Original Research

Published on 20 Sep 2021

Chemical Inhibition of Apurinic-Apyrimidinic Endonuclease 1 Redox and DNA Repair Functions Affects the Inflammatory Response via Different but Overlapping Mechanisms

in Signaling

Thais Teixeira Oliveira
Fabrícia Lima Fontes-Dantas
Rayssa Karla de Medeiros Oliveira
Daniele Maria Lopes Pinheiro
Leonam Gomes Coutinho
Vandeclecio Lira da Silva
Sandro José de Souza
Lucymara Fassarella Agnez-Lima

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.731588

6,675 views
11 citations

Original Research

Published on 17 Sep 2021

CRISPR-Based Activation of Endogenous Expression of TPM1 Inhibits Inflammatory Response of Primary Human Coronary Artery Endothelial and Smooth Muscle Cells Induced by Recombinant Human Tumor Necrosis Factor α

in Signaling

Maciej Gagat
Wioletta Zielińska
Klaudia Mikołajczyk
Jan Zabrzyński
Adrian Krajewski
Anna Klimaszewska-Wiśniewska
Dariusz Grzanka
Alina Grzanka

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.668032

8,230 views
23 citations

Original Research

Published on 17 Sep 2021

Ion Mobility Coupled to a Time-of-Flight Mass Analyzer Combined With Fragment Intensity Predictions Improves Identification of Classical Bioactive Peptides and Small Open Reading Frame-Encoded Peptides

in Signaling

Marlies K. R. Peeters
Geert Baggerman
Ralf Gabriels
Elise Pepermans
Gerben Menschaert
Kurt Boonen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.720570

7,116 views
15 citations

Review

Published on 17 Sep 2021

Toll Like Receptors as Sensors of the Tumor Microbial Dysbiosis: Implications in Cancer Progression

in Signaling

Valentino Le Noci
Giancarla Bernardo
Francesca Bianchi
Elda Tagliabue
Michele Sommariva
Lucia Sfondrini

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.732192

7,190 views
43 citations

1,291 articles

articles

Global SUMOylome Adjustments in Basal Defenses of Arabidopsis thaliana Involve Complex Interplay Between SMALL-UBIQUITIN LIKE MODIFIERs and the Negative Immune Regulator SUPPRESSOR OF rps4-RLD1

SUMOylation of Arginyl tRNA Synthetase Modulates the Drosophila Innate Immune Response

Obesity Inhibits Angiogenesis Through TWIST1-SLIT2 Signaling

Development and Validation of an IL6/JAK/STAT3-Related Gene Signature to Predict Overall Survival in Clear Cell Renal Cell Carcinoma

Distinct Identity of GLP-1R, GLP-2R, and GIPR Expressing Cells and Signaling Circuits Within the Gastrointestinal Tract

Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro

Editorial: Emerging Mechanisms for Skeletal Muscle Mass Regulation

Lgr4 Regulates Oviductal Epithelial Secretion Through the WNT Signaling Pathway

An Adipose-Derived Injectable Sustained-Release Collagen Scaffold of Adipokines Prepared Through a Fast Mechanical Processing Technique for Preventing Skin Photoaging in Mice

Single-Molecule Imaging Reveals Rapid Estradiol Action on the Surface Movement of AMPA Receptors in Live Neurons

Organoid Technology: A Reliable Developmental Biology Tool for Organ-Specific Nanotoxicity Evaluation

Folding Mitochondrial-Mediated Cytosolic Proteostasis Into the Mitochondrial Unfolded Protein Response

Thrombospondin-4 Is a Soluble Dermal Inflammatory Signal That Selectively Promotes Fibroblast Migration and Keratinocyte Proliferation for Skin Regeneration and Wound Healing

Dermatan-4-O-Sulfotransferase-1 Contributes to the Undifferentiated State of Mouse Embryonic Stem Cells

Beyond Neurons: Long Distance Communication in Development and Cancer

SALL1 Modulates CBX4 Stability, Nuclear Bodies, and Regulation of Target Genes

Human Three-Finger Protein Lypd6 Is a Negative Modulator of the Cholinergic System in the Brain

Direct Evidence of Endothelial Dysfunction and Glycocalyx Loss in Dermal Biopsies of Patients With Chronic Kidney Disease and Their Association With Markers of Volume Overload

Mitochondrial Impairment by MitoBloCK-6 Inhibits Liver Cancer Cell Proliferation

Galectin-3 Enhances Vascular Endothelial Growth Factor-A Receptor 2 Activity in the Presence of Vascular Endothelial Growth Factor

Chemical Inhibition of Apurinic-Apyrimidinic Endonuclease 1 Redox and DNA Repair Functions Affects the Inflammatory Response via Different but Overlapping Mechanisms

CRISPR-Based Activation of Endogenous Expression of TPM1 Inhibits Inflammatory Response of Primary Human Coronary Artery Endothelial and Smooth Muscle Cells Induced by Recombinant Human Tumor Necrosis Factor α

Ion Mobility Coupled to a Time-of-Flight Mass Analyzer Combined With Fragment Intensity Predictions Improves Identification of Classical Bioactive Peptides and Small Open Reading Frame-Encoded Peptides

Toll Like Receptors as Sensors of the Tumor Microbial Dysbiosis: Implications in Cancer Progression