Frontiers in Cell and Developmental Biology

Original Research

Published on 26 Jun 2025

Comparative analysis of small molecule and growth factor-derived human induced pluripotent stem cell-derived hepatocyte-like cells

in Stem Cell Research

Faizal Z. Asumda
Shadia Alzoubi
Kiyasha Padarath
Kimya Jones
Ravindra Kolhe
Ashis Kumar Mondal
Ahmet Alptekin
Wenbo Zhi
Tae Jin Lee
Robert C. Huebert

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1594340

2,565 views

Original Research

Published on 24 Jun 2025

Wharton’s jelly mesenchymal stromal cells derived from preterm umbilical cord reveal a hepatogenic potential

in Stem Cell Research

F. Timoneri
M. Lo Iacono
S. Corrao
G. Alberti
G. Amico
T. Corsello
P. G. Conaldi
Eleonora Russo
G. La Rocca

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1626353

2,500 views
2 citations

Original Research

Published on 23 Jun 2025

Rnd3 deletion affects neuroblast behavior through the RhoA/ROCK pathway but not neural stem cells in postnatal mice subventricular zone

in Stem Cell Research

Amalia Solana-Orts
Germán Belenguer
Begoña Ballester-Lurbe
Olga Gómez
Ignacio Pérez-Roger
José Terrado
Enric Poch
Alexandra Bizy

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1612177

2,520 views

Review

Published on 20 Jun 2025

Current approaches for Usher syndrome disease models and developing therapies

in Stem Cell Research

Fiona K. Leith
Joey Lye
Derek S. Delaney
Samuel McLenachan
Fred K. Chen
Marcus D. Atlas
Elaine Y. M. Wong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1547523

5,450 views
1 citation

Review

Published on 20 Jun 2025

Mechanistic insights into adipose-derived stem cells and exosomes in ischemia-reperfusion injury repair: from shared pathways to organ-specific therapeutics

in Stem Cell Research

Jiaqian Si
Jie Wang
Hao Dai
Tuochen Lv
Songyun Zhao
Wanying Chen
Liqun Li
Siqi Ding
Yucang He

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1621289

4,433 views
1 citation

Original Research

Published on 19 Jun 2025

Comparative cardiomyocyte differentiation potential of rat adipose-derived mesenchymal stem cells from two anatomical sites: metabolomic profiling and pathway analysis

in Stem Cell Research

Ahmed Farag
Haney Samir
Sai Koung Ngeun
Masahiro Kaneda
Hanan Hendawy
Ken Takahashi
Ryou Tanaka

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1604605

2,461 views

Original Research

Published on 16 Jun 2025

Preclinical efficacy and safety evaluation of BD211 autologous CD34+ hematopoietic stem cell injection for transfusion-dependent β-thalassemia in NCG-X mice

in Stem Cell Research

Xuedong Dai
Zike Li
Shuang Chen
Ying Huang
Sikai Ling
Quanjun Wang
Qi Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1607707

2,525 views
1 citation

Review

Published on 10 Jun 2025

Progress of bone marrow mesenchymal stem cell transplantation on neural plasticity in brain

in Stem Cell Research

Wenjing Li
Xiaohua Liu
Jingjing Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1589169

3,450 views
1 citation

Perspective

Published on 09 Jun 2025

Hypoxia-induced metabolic reprogramming in mesenchymal stem cells: unlocking the regenerative potential of secreted factors

in Stem Cell Research

Wendy V. Jaraba-Álvarez
Ashanti C. Uscanga-Palomeque
Vanesa Sanchez-Giraldo
Claudia Madrid
Hector Ortega-Arellano
Karolynn Halpert
Carolina Quintero-Gil

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609082

5,352 views
8 citations

Brief Research Report

Published on 05 Jun 2025

Molecular analysis of RAX2-regulated retinal development using human retinal organoids at a single-cell resolution

in Stem Cell Research

Shaojun Wang
Yi Sun
Jie Na
Yue Huang
Guang Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609826

2,909 views

Original Research

Published on 04 Jun 2025

Differential regulation of MMP activity by TGFβ1 in fast- and slow- twitch muscle repair: insights from EDL and soleus muscle-derived myoblasts

in Stem Cell Research

Paulina Kasprzycka
Maria Anna Ciemerych
Malgorzata Zimowska

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1592512

2,007 views
1 citation

Original Research

Published on 03 Jun 2025

Induced neural stem cells ameliorate blood-brain barrier injury by modulating the calcium signaling pathway of astrocyte in cerebral ischemia-reperfusion rats

in Stem Cell Research

Xueyun Liang
Chuanshang Cao
Ningmei Liu
Dongmei Chen
Ting Liu
Haibin Ma
Jiaxin Liu
Taojuan Wu
Jianguo Niu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1611226

2,434 views
2 citations

Review

Published on 30 May 2025

Survey of transcriptome analyses of hippocampal neurogenesis with focus on adult dentate gyrus stem cells

in Stem Cell Research

Laura Micheli
Maurizia Caruso
Giorgio D’Andrea
Daniel Volpe
Manuela Ceccarelli
Felice Tirone

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1605116

4,472 views
1 citation

Review

Published on 30 May 2025

“Armed in-vitro retina”-generating microglial retinal organoids, where are we now?

in Stem Cell Research

Yaohong Liu
Lixiong Gao
Wenqian Chen
Yuhan Yan
Zi Ye
Zhaohui Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1574283

4,348 views

Review

Published on 30 May 2025

Biomedical applications of organoids derived from the digestive system

in Stem Cell Research

Zhensheng Xu
Zhongwen Lei
Qiuhua Cheng
Yuanhui Gao
Yang Xiang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1599384

4,180 views

Original Research

Published on 27 May 2025

Mesenchymal stem cell-derived exosome subpopulations remained consistent for 28 culture days, displaying therapeutic effects in a silicosis mouse model

in Stem Cell Research

Lina Zhang
Jing Jin
Liguang Sun
Gang Hou
Mingming Deng
Yiding Bian
Jianming Liu
Wei Cheng
Shaoliang Xing
Wenjia Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1550447

4,373 views
4 citations

Brief Research Report

Published on 21 May 2025

Synchrotron radiation FTIR microspectroscopy enables measuring dynamic cell identity patterning during human 3D differentiation

in Stem Cell Research

Tanja Dučić
Francisco Rodriguez-Yañez
Elena Gonzalez-Muñoz

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1569187

2,440 views
1 citation

Editorial

Published on 16 May 2025

Editorial: Senescence and reprogramming: hallmarks in aging and disease

in Stem Cell Research

F. Javier González-Rico
Jiyue Zhu
Guangyong Peng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1622682

2,463 views

Original Research

Published on 16 May 2025

Optimal Sca-1-based procedure for purifying mouse adipose-derived mesenchymal stem cells with enhanced proliferative and differentiation potential

in Stem Cell Research

Xingyu Tao
Jialian Wang
Yuan Yan
Peifeng Cheng
Bin Liu
Huimin Du
Bailin Niu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1566670

3,258 views
28 citations

Original Research

Published on 15 May 2025

Optimizing single cell RNA sequencing of stem cells. A streamlined workflow for enhanced sensitivity and reproducibility in hematopoietic studies. The use of human umbilical cord blood-derived hematopoietic stem and progenitor cells

in Stem Cell Research

Justyna Jarczak
Patrycja Kieszek
Mariusz Z. Ratajczak
Magdalena Kucia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1590889

3,523 views

Original Research

Published on 13 May 2025

Revolutionizing bone regeneration and wound healing: Mechanical stromal vascular fraction and hyaluronic acid in a mouse calvarial defect model

in Stem Cell Research

Riccardo Ossanna
Lindsey Alejandra Quintero Sierra
Sara Ghazanfar Tehrani
Vivekanand Jha
Chiara Curatola
Alice Busato
Anita Conti
Giamaica Conti
Nicola Zingaretti
Pier Camillo Parodi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1582083

3,837 views

Original Research

Published on 09 May 2025

Characterization and neurogenic responses of primary and immortalized Müller glia

in Stem Cell Research

Thi-Hang Tran
Donny Lukmanto
Mei Chen
Olaf Strauß
Toshiharu Yamashita
Osamu Ohneda
Shinichi Fukuda

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1513163

2,559 views

Review

Published on 08 May 2025

A comprehensive analysis of induced pluripotent stem cell (iPSC) production and applications

in Stem Cell Research

Margarita Matiukhova
Anastasia Ryapolova
Vladimir Andriianov
Vasiliy Reshetnikov
Sophia Zhuravleva
Roman Ivanov
Alexander Karabelsky
Ekaterina Minskaia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1593207

13,574 views
7 citations

Original Research

Published on 08 May 2025

In vivo and in vitro therapeutic evaluation of bone marrow-derived mesenchymal stem cells in liver cancer treatment

in Stem Cell Research

Abdulrahman Johor
A. S. M. Mahadiuzzaman
Abdulaziz Abdullah Alqusayer
Saleh Abdulaziz Alkarim
F. A. Dain Md Opo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1521809

3,319 views

1,782 articles

articles

Comparative analysis of small molecule and growth factor-derived human induced pluripotent stem cell-derived hepatocyte-like cells

Wharton’s jelly mesenchymal stromal cells derived from preterm umbilical cord reveal a hepatogenic potential

Rnd3 deletion affects neuroblast behavior through the RhoA/ROCK pathway but not neural stem cells in postnatal mice subventricular zone

Current approaches for Usher syndrome disease models and developing therapies

Mechanistic insights into adipose-derived stem cells and exosomes in ischemia-reperfusion injury repair: from shared pathways to organ-specific therapeutics

Comparative cardiomyocyte differentiation potential of rat adipose-derived mesenchymal stem cells from two anatomical sites: metabolomic profiling and pathway analysis

Preclinical efficacy and safety evaluation of BD211 autologous CD34+ hematopoietic stem cell injection for transfusion-dependent β-thalassemia in NCG-X mice

Progress of bone marrow mesenchymal stem cell transplantation on neural plasticity in brain

Hypoxia-induced metabolic reprogramming in mesenchymal stem cells: unlocking the regenerative potential of secreted factors

Molecular analysis of RAX2-regulated retinal development using human retinal organoids at a single-cell resolution

Differential regulation of MMP activity by TGFβ1 in fast- and slow- twitch muscle repair: insights from EDL and soleus muscle-derived myoblasts

Induced neural stem cells ameliorate blood-brain barrier injury by modulating the calcium signaling pathway of astrocyte in cerebral ischemia-reperfusion rats

Survey of transcriptome analyses of hippocampal neurogenesis with focus on adult dentate gyrus stem cells

“Armed in-vitro retina”-generating microglial retinal organoids, where are we now?

Biomedical applications of organoids derived from the digestive system

Mesenchymal stem cell-derived exosome subpopulations remained consistent for 28 culture days, displaying therapeutic effects in a silicosis mouse model

Synchrotron radiation FTIR microspectroscopy enables measuring dynamic cell identity patterning during human 3D differentiation

Editorial: Senescence and reprogramming: hallmarks in aging and disease

Optimal Sca-1-based procedure for purifying mouse adipose-derived mesenchymal stem cells with enhanced proliferative and differentiation potential

Optimizing single cell RNA sequencing of stem cells. A streamlined workflow for enhanced sensitivity and reproducibility in hematopoietic studies. The use of human umbilical cord blood-derived hematopoietic stem and progenitor cells

Revolutionizing bone regeneration and wound healing: Mechanical stromal vascular fraction and hyaluronic acid in a mouse calvarial defect model

Characterization and neurogenic responses of primary and immortalized Müller glia

A comprehensive analysis of induced pluripotent stem cell (iPSC) production and applications

In vivo and in vitro therapeutic evaluation of bone marrow-derived mesenchymal stem cells in liver cancer treatment