Frontiers in Cell and Developmental Biology

Review

Published on 06 Jan 2026

Brain-derived extracellular vesicles potentially mediate crosstalk with peripheral organs in neurodegenerative diseases

Ramzi H. Hamdalla
Vibha B. Bhaskar
Changhai Tian

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1710150

1,372 views

Original Research

Published on 05 Jan 2026

Kv2.1 negatively regulates Reissner fiber development

R. Rosa Amini
Ruchi P. Jain
Justyna Jędrychowska
Vladimir Korzh

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1720752

1,115 views

Review

Published on 05 Jan 2026

AI-driven biomaterial design: an intelligent closed loop from reverse design to biological response

Minglei Liu
Yichuan Zhou
Xiaohan Mei
Zehao Yu
Boyun Guan
Yi Xiao
Shixian Liu
Hao Wang
Yanguo Qin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1755565

1,408 views

Original Research

Published on 05 Jan 2026

Epigenetic, histological and clinical characterization of preeclampsia in oocyte donation pregnancies: insights into immune dysregulation and microRNA-mediated pathways

Irma Saulle
Maria Di Giminiani
Ozge Yazici
Claudio Fenizia
Manuela Nebuloni
Roberta Rossi
Mara Biasin
Valeria Savasi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1718305

889 views

Review

Published on 05 Jan 2026

Modeling human placental biology: a review of organoid technologies

Alaijah Bashi
Tyana Joseph
Viviane Schuch
Erica L. Johnson

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1693923

1,198 views
1 citation

Review

Published on 05 Jan 2026

The leading role of MYC in DNA damage response: exploring opportunities for therapeutic inhibition

Fabio Giuntini
Jonathan R. Whitfield
Daniel Massó-Vallés
Laura Soucek

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1726515

1,362 views

Review

Published on 05 Jan 2026

Embryo-secreted microRNAs enable non-invasive assessment of chromosomal status and viability in in vitro fertilization

Masoumeh Esmaeilivand
Mohammad Hossein Nasr-Esfahani

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1747211

830 views

Original Research

Published on 05 Jan 2026

The predictive value of necroptosis-related lncRNAs in prostate cancer prognosis and their potential to distinguish between cold and hot tumors

Ke Zhang
Kai Li
Junpeng Deng
Chunchun Zhao
Fei Wang
JianJun Xie

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1722671

770 views

Original Research

Published on 05 Jan 2026

Mandibular extracellular vesicles mediate morphogenesis and mineralization of tooth germs in miniature swine through the miR-206/HDAC4 signaling axis

Xiaoyu Cao
Duanlin Ma
Yujiao Song
Yiping Gao
Wen Liu
Xiaohong Du
Xiaojun Sun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1707072

1,026 views

Review

Published on 05 Jan 2026

The varied functions of the giant muscle scaffold protein obscurin

James Novac Di Paola
Frieder Schöck

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1689326

1,010 views

Original Research

Published on 05 Jan 2026

A novel protein encoded by circIMP3 promotes prostate cancer progression by regulating alternative splicing and tumor microenvironment

Wenren Zuo
Weizhou Huang
Haojie Chen
Yan Xu
Yang Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1722674

1,089 views

Review

Published on 02 Jan 2026

The transcribed ultraconserved regions: emerging players in colorectal cancer biology and therapy

Yi Zhang
Zichen Wei
Xin Wang
Pan Wang
Lei Pang
Hongliang Dong
Han Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1599891

905 views

Original Research

Published on 02 Jan 2026

Metabolic patterns predispose human pluripotent stem cells to spatial organization of cell fate

Chunhao Deng
Zhaoying Zhang
Xia Xiao
Carlos Godoy-Parejo
Faxiang Xu
Chengcheng Song
Huanyi Lin
Qinru Li
Shicai Fang
Weiwei Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1696372

926 views

Review

Published on 02 Jan 2026

4-HNE-induced cellular dysfunction from lipid peroxidation: a potential therapeutic target in diabetic cardiomyopathy

Nan Jiang
Yanchun Ma
Huijun Chen
Chengjia Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1663094

1,567 views

Original Research

Published on 02 Jan 2026

Preclinical biodistribution and safety evaluation of human iPSC-derived dopaminergic neural progenitor cells for Parkinson’s disease

Ying Huang
Hairuo Wen
Lily Li
Lulu Li
Qianqian Li
Chao Qin
Yiyang Mao
Zhi Lin
Hua Jiang
Frank Zhu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1701748

977 views

Review

Published on 02 Jan 2026

Research progress of stem cells in the treatment of atherosclerosis

Peifei Shi
Chao Ren
Hongjie Tong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1722416

1,799 views

Original Research

Accepted on 30 Dec 2025

The regulation of pedicle initiation by androgens in sika deer (Cervus nippon)

Zhen Liu
Xiongzhi Li
Qianqian Guo
Li Guangyu
Hongmei Sun
Jiangbin Zou
Baorui Xing
RANA AKHTAR
Yingyan Guo
Haiping Zhao

Frontiers in Cell and Developmental Biology

267 views

Original Research

Published on 30 Dec 2025

Fibroblast growth factor 9 activates fibroblast activation and drives the progress of shoulder stiffness

Jian Xu
Weihan Yu
Yunkang Kang
Dongqiang Yang
Yanlong Liu
Wenzhi Bi
Haiyang Yu
Beijie Qi
Biao Guo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1731453

850 views

Original Research

Accepted on 29 Dec 2025

Computational Analysis of Treatment Resistant Cancer Cells

Alexandre Matov

Frontiers in Cell and Developmental Biology

Original Research

Published on 29 Dec 2025

Integration of peripheral blood-based systemic inflammatory indices and retinal imaging using interpretable machine learning for predicting anti-VEGF treatment response in macular edema secondary to retinal vein occlusion

Jiajun Li
Yao Lu
Qianzi Jin
Siqi Wu
Xiangzhong Xu
Qin Jiang
Keran Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1732963

1,128 views

Review

Published on 23 Dec 2025

Fibroblast PI3K/AKT signaling and extracellular matrix homeostasis: mechanisms, targets, and delivery challenges

Chunyun Fang
Zitao Zeng
Bin Ni
Xiaochun Wen
Zhipeng Fang
Junrong Zou
Guoxi Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1681875

1,959 views

Review

Published on 19 Dec 2025

Recent advances in the role of CARM1 in skeletal muscle development, metabolism, and homeostasis maintenance

Xiaojing Xie
Menghuan Li
Yue Zhang
Zhenwei Bao
Xuejie Yi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1709515

1,210 views

Original Research

Published on 19 Dec 2025

Sexual dimorphism in the DNA methylation pattern after immune stimulation in the zebrafish (Danio rerio) gonads

M. Salazar
M. Caballero-Huertas
T. A. van Gelderen
M. N. Krabbe
M. Gut
S. Heath
A. Esteve
L. Ribas

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1720219

1,415 views

13,016 Publications

volumes

Volume 13 - 2025

Brain-derived extracellular vesicles potentially mediate crosstalk with peripheral organs in neurodegenerative diseases

Kv2.1 negatively regulates Reissner fiber development

AI-driven biomaterial design: an intelligent closed loop from reverse design to biological response

Epigenetic, histological and clinical characterization of preeclampsia in oocyte donation pregnancies: insights into immune dysregulation and microRNA-mediated pathways

Modeling human placental biology: a review of organoid technologies

The leading role of MYC in DNA damage response: exploring opportunities for therapeutic inhibition

Embryo-secreted microRNAs enable non-invasive assessment of chromosomal status and viability in in vitro fertilization

The predictive value of necroptosis-related lncRNAs in prostate cancer prognosis and their potential to distinguish between cold and hot tumors

Mandibular extracellular vesicles mediate morphogenesis and mineralization of tooth germs in miniature swine through the miR-206/HDAC4 signaling axis

The varied functions of the giant muscle scaffold protein obscurin

A novel protein encoded by circIMP3 promotes prostate cancer progression by regulating alternative splicing and tumor microenvironment

The transcribed ultraconserved regions: emerging players in colorectal cancer biology and therapy

Metabolic patterns predispose human pluripotent stem cells to spatial organization of cell fate

4-HNE-induced cellular dysfunction from lipid peroxidation: a potential therapeutic target in diabetic cardiomyopathy

Preclinical biodistribution and safety evaluation of human iPSC-derived dopaminergic neural progenitor cells for Parkinson’s disease

Research progress of stem cells in the treatment of atherosclerosis

The regulation of pedicle initiation by androgens in sika deer (Cervus nippon)

Fibroblast growth factor 9 activates fibroblast activation and drives the progress of shoulder stiffness

Computational Analysis of Treatment Resistant Cancer Cells

Integration of peripheral blood-based systemic inflammatory indices and retinal imaging using interpretable machine learning for predicting anti-VEGF treatment response in macular edema secondary to retinal vein occlusion

Fibroblast PI3K/AKT signaling and extracellular matrix homeostasis: mechanisms, targets, and delivery challenges

Recent advances in the role of CARM1 in skeletal muscle development, metabolism, and homeostasis maintenance

Sexual dimorphism in the DNA methylation pattern after immune stimulation in the zebrafish (Danio rerio) gonads

Volume 14 - 2026

Effectiveness Comparison of Domestic versus Imported Immune Checkpoint Inhibitors in Neoadjuvant Chemoimmunotherapy for Esophageal Squamous Cell Carcinoma