Frontiers in Cell and Developmental Biology

Brief Research Report

Published on 19 Dec 2025

Therapy to teratology: chronic paternal antioxidant supplementation alters offspring placental architecture and craniofacial morphogenesis in a mouse model

Destani D. Derrico
Katherine Z. Scaturro
Erin E. Murray
Eliezar Guillen
Nathan S. Truss
Katherine A. Fairly
Samantha L. Higgins
Sanat S. Bhadsavle
Michael C. Golding

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1697843

2,044 views

Original Research

Published on 19 Dec 2025

Association of fibronectin 1 deregulation with tyrosine kinase inhibitor resistance in chronic myeloid leukemia

Lina Tiedemann
Sivahari Prasad Gorantla
Philine Ahlf
Lucie Sophie Schmidt
Christiane Pott
Merit Litterst
Vicki Waetzig
Inga Nagel
Johanna Ruemenapp
Nikolas von Bubnoff

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1725857

1,125 views

Original Research

Published on 18 Dec 2025

Inflammation centered muscle signature of sarcopenia from postmenopausal women in Shanghai China

Yongqian Fan
Shangjin Lin
Ming Ling
Tao Cui
Cong Chen
Fengjian Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1726045

1,188 views

Original Research

Published on 18 Dec 2025

Cecal growth factors promote enteric neurosphere formation and hindgut colonization in the avian model

Ádám Soós
Emőke Szőcs
Viktória Halasy
Zsanna Gecse
Fruzsina Mógor
Csenge Jurenka
Katalin Kocsis
Jitka Mucksová
Jiří Hejnar
Nándor Nagy

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1681844

1,441 views

Methods

Published on 18 Dec 2025

Optimized protocols for generating half-sized embryos from separated first two blastomeres in green sea urchin and Xenopus laevis

Eugeny E. Orlov
Polina S. Timoshina
Elena A. Parshina
Fedor M. Eroshkin
Maria A. Bannikova
Andrey G. Zaraisky

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1730288

1,362 views

Original Research

Published on 18 Dec 2025

Disruption of Swell1/VRAC function impairs initial hemodynamics and activates compensatory leukotriene signaling in zebrafish circulation development

Yen-Tzu Tseng
Chia-Teng Chang
Wei-Chun HuangFu
I.-Hsuan Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1719544

1,381 views

Mini Review

Published on 18 Dec 2025

METTL5 in physiology and pathology: mechanisms and implications

Chunhong Li
Xiulin Jiang
Yixiao Yuan
Qiang Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1708541

1,359 views

Review

Published on 18 Dec 2025

The role of ADAR1 in human pathophysiology

Jiahao Li
Yushan Xiao
Xiaofeng Li
Yan Dai

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1672970

1,594 views

Original Research

Published on 18 Dec 2025

Osteoprogenitor cells from non-regenerative bone show greater resistance to cellular stress than those from regenerative bone

Joshua Broussard
Sylvia Culpepper
Tyrel Long
Alexander J. Trostle
Robert J. Tower
Mimi C. Sammarco
Jennifer Simkin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1684670

1,382 views

Original Research

Published on 18 Dec 2025

Targeted peptide modification of mesenchymal stem cells enhances their therapeutic efficacy in the treatment of idiopathic pulmonary fibrosis

Zelin Lei
Rui Jia
Yixuan Ren
Yirun Zhao
Yun Wang
Wenqian Cao
Xue Bai
Yali Peng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1710750

1,626 views

Mini Review

Published on 18 Dec 2025

Metabolic reprogramming in bone metastasis of human cancers

Tianda Li
Ziyi Wang
Haitao Yang
Yihan Kang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1711592

1,307 views

Review

Published on 17 Dec 2025

The role of MMPs in intracerebral hemorrhage

Xiaofei Guan
Meiren Li
Huimin Li
Zeqin Guo
Muhammad Saad Ullah
Xiaoqun Liu
Moxin Wu
Wenmin Yu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1667228

1,835 views

Review

Published on 17 Dec 2025

Ferroptosis at the intersection of osteoarthritis and bone metabolism: mechanistic links and therapeutic prospects

Jing Xiao
Yan Zhu
Jingjing Chen
Yujie Hong
Yang Cao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1722435

1,790 views

Review

Published on 17 Dec 2025

R-loops and small RNA regulatory interactions: mechanisms and clinical perspectives

Si-Yao Wang
Ya-Ni Liu
Si-Qiao Zhao
Wen Liu
Jin-Long Hu
Fan Yang
Sheng Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1727548

1,161 views

Original Research

Published on 16 Dec 2025

Microglia response and function in a chronic model of photoreceptor damage

Deepa Raghavan
Olivia Jeakle
Yasmeen Berry
Majd Victor
Ryan Thummel

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1699271

1,537 views

Review

Published on 16 Dec 2025

Endoplasmic reticulum stress in non-small cell lung cancer: a review of therapeutic agents, mechanistic insights, and implications for therapy

Qiong Luo
Xinxin Gao
Peng Meng
Xiao Qi
Wen Wang
Shan Li
Linlin Duan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1693023

1,717 views

Original Research

Published on 16 Dec 2025

Low-dose letrozole-HMG regimen reverses letrozole-induced endometrial impairment and improves frozen embryo transfer outcomes

Zhonglin Xiao
Feng Wang
Yali Yang
Tianxia Xiao
Jie Chen
Mengxia Li
Haizhen Liao
Chiawei Chu
Xiujun Fan
Jian V. Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1725350

1,379 views

Original Research

Published on 16 Dec 2025

Image-text guided fundus vessel segmentation via attention mechanism and gated residual learning

Jianguo Xu
Qingyou Liu
Jianxin Shen
Rong Tan
Sukun Tian
Wei Chi
Weihua Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1710343

907 views

Original Research

Published on 16 Dec 2025

Multi-omics analysis reveals a protective role of endogenous proline in sheep oocyte vitrification and its therapeutic application

Airixiati Dilixiati
Xi Zhao
Aikebaier Aihemaiti
Weijian Li
Chen Fan
Guodong Zhao
Abulizi Wusiman
Xuguang Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1714529

1,379 views

Review

Published on 16 Dec 2025

Aging-associated mechanisms and metabolic vulnerabilities in esophageal carcinoma: an integrative review

Qiwei Liu
Zhiyu Xie
Wei Li
Mengxiang Li
Yijun Qi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1714824

1,487 views

Review

Published on 12 Dec 2025

Cartilage organoids: an emerging platform for novel osteoarthritis therapies

Bimin Gao
Zecai Chen
Yufeng Long
Feng He
Donghao Gan
Weihong Yi
Guozhi Xiao
Jiangdong Ren
Lei Qin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1668766

2,053 views

Methods

Published on 12 Dec 2025

Establishment of RpHluorin2-expressing cell and its application in monitoring JTC-801-induced alkaliptosis via multi-dimensional fluorescence detection approaches

Jie Guo
Feng-Yi Mai
Xin-Yu Li
Jing-Rong Liang
Wen-Tao Yang
Chen-Guang Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1727740

1,093 views
1 citation

Editorial

Published on 12 Dec 2025

Editorial: Antioxidants in mitigating oxidative stress-induced damage

Marisol Fernandez-Ortiz
Ramy K. A. Sayed
Russel J. Reiter

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1756697

950 views

Original Research

Published on 12 Dec 2025

Effects of high-altitude environments on intervertebral disc degeneration and transcriptome profiling of the nucleus pulposus

Jiawei Fu
Rong Tang
Tianfei Ran
Yue Zhou
Bo Huang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1709844

1,186 views

13,016 Publications

volumes

Volume 13 - 2025

Therapy to teratology: chronic paternal antioxidant supplementation alters offspring placental architecture and craniofacial morphogenesis in a mouse model

Association of fibronectin 1 deregulation with tyrosine kinase inhibitor resistance in chronic myeloid leukemia

Inflammation centered muscle signature of sarcopenia from postmenopausal women in Shanghai China

Cecal growth factors promote enteric neurosphere formation and hindgut colonization in the avian model

Optimized protocols for generating half-sized embryos from separated first two blastomeres in green sea urchin and Xenopus laevis

Disruption of Swell1/VRAC function impairs initial hemodynamics and activates compensatory leukotriene signaling in zebrafish circulation development

METTL5 in physiology and pathology: mechanisms and implications

The role of ADAR1 in human pathophysiology

Osteoprogenitor cells from non-regenerative bone show greater resistance to cellular stress than those from regenerative bone

Targeted peptide modification of mesenchymal stem cells enhances their therapeutic efficacy in the treatment of idiopathic pulmonary fibrosis

Metabolic reprogramming in bone metastasis of human cancers

The role of MMPs in intracerebral hemorrhage

Ferroptosis at the intersection of osteoarthritis and bone metabolism: mechanistic links and therapeutic prospects

R-loops and small RNA regulatory interactions: mechanisms and clinical perspectives

Microglia response and function in a chronic model of photoreceptor damage

Endoplasmic reticulum stress in non-small cell lung cancer: a review of therapeutic agents, mechanistic insights, and implications for therapy

Low-dose letrozole-HMG regimen reverses letrozole-induced endometrial impairment and improves frozen embryo transfer outcomes

Image-text guided fundus vessel segmentation via attention mechanism and gated residual learning

Multi-omics analysis reveals a protective role of endogenous proline in sheep oocyte vitrification and its therapeutic application

Aging-associated mechanisms and metabolic vulnerabilities in esophageal carcinoma: an integrative review

Cartilage organoids: an emerging platform for novel osteoarthritis therapies

Establishment of RpHluorin2-expressing cell and its application in monitoring JTC-801-induced alkaliptosis via multi-dimensional fluorescence detection approaches

Editorial: Antioxidants in mitigating oxidative stress-induced damage

Effects of high-altitude environments on intervertebral disc degeneration and transcriptome profiling of the nucleus pulposus