Frontiers in Cell and Developmental Biology

Original Research

Published on 16 Dec 2025

Low-dose letrozole-HMG regimen reverses letrozole-induced endometrial impairment and improves frozen embryo transfer outcomes

Zhonglin Xiao
Feng Wang
Yali Yang
Tianxia Xiao
Jie Chen
Mengxia Li
Haizhen Liao
Chiawei Chu
Xiujun Fan
Jian V. Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1725350

1,384 views

Review

Published on 16 Dec 2025

Aging-associated mechanisms and metabolic vulnerabilities in esophageal carcinoma: an integrative review

Qiwei Liu
Zhiyu Xie
Wei Li
Mengxiang Li
Yijun Qi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1714824

1,491 views

Original Research

Published on 16 Dec 2025

Image-text guided fundus vessel segmentation via attention mechanism and gated residual learning

Jianguo Xu
Qingyou Liu
Jianxin Shen
Rong Tan
Sukun Tian
Wei Chi
Weihua Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1710343

910 views

Original Research

Published on 16 Dec 2025

Multi-omics analysis reveals a protective role of endogenous proline in sheep oocyte vitrification and its therapeutic application

Airixiati Dilixiati
Xi Zhao
Aikebaier Aihemaiti
Weijian Li
Chen Fan
Guodong Zhao
Abulizi Wusiman
Xuguang Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1714529

1,381 views

Methods

Published on 12 Dec 2025

Establishment of RpHluorin2-expressing cell and its application in monitoring JTC-801-induced alkaliptosis via multi-dimensional fluorescence detection approaches

Jie Guo
Feng-Yi Mai
Xin-Yu Li
Jing-Rong Liang
Wen-Tao Yang
Chen-Guang Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1727740

1,095 views
1 citation

Review

Published on 12 Dec 2025

Cartilage organoids: an emerging platform for novel osteoarthritis therapies

Bimin Gao
Zecai Chen
Yufeng Long
Feng He
Donghao Gan
Weihong Yi
Guozhi Xiao
Jiangdong Ren
Lei Qin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1668766

2,066 views

Editorial

Published on 12 Dec 2025

Editorial: Antioxidants in mitigating oxidative stress-induced damage

Marisol Fernandez-Ortiz
Ramy K. A. Sayed
Russel J. Reiter

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1756697

951 views

Original Research

Published on 12 Dec 2025

Effects of high-altitude environments on intervertebral disc degeneration and transcriptome profiling of the nucleus pulposus

Jiawei Fu
Rong Tang
Tianfei Ran
Yue Zhou
Bo Huang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1709844

1,189 views

Review

Published on 12 Dec 2025

Advances in adhesion interfaces of peripheral nerve repair materials: mechanism, classification, evaluation method, and functionalization

Qi Meng
Meng Zhang
Yichong Zhang
Haoran Jiang
Yang Qu
Ci Li
Chenyujun Hu
Zhihao Lin
Bohan Xing
Fengxue Zhu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1725351

1,335 views

Opinion

Published on 11 Dec 2025

The AI-driven blueprint: decoding intervertebral disc repair mechanisms for intelligent biomaterial design

Yuanzhen Shi
Yifan Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1751851

1,020 views

Original Research

Published on 11 Dec 2025

Identification of shared lactylation-related gene signatures between osteoporosis and chronic kidney disease

Dong Liu
Ying Xia
Hui Wang
Kaiqiang Sun
Shunmin Wang
Yaping Yu
Xiaojie Dai

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1719273

1,525 views

Original Research

Published on 11 Dec 2025

Knowledge-enhanced AI drives diagnosis of multiple retinal diseases in fundus fluorescein angiography

Ming-Ming Duan
Hui Qi
Xiang Tu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1703606

836 views

Review

Published on 11 Dec 2025

Single-cell cloning and its approaches

Amany E. S. Ammar

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1678157

2,082 views

Original Research

Published on 11 Dec 2025

Molecular insights into Atorvastatin’s role in delaying intervertebral disc degeneration

Yupeng Li
Linghao Wang
Xingjie Wang
Kang Li
Qian Wang
Kai Gao
Cunxin Zhang
Chaoliang Lv

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1693951

1,024 views

Original Research

Published on 11 Dec 2025

Mathematical modeling reveals cell differentiation processes and progenitor kinetics necessary for proper nephrogenesis

Matthew R. Hawkins
Stuart E. Jones
Hannah M. Wesselman
Cecilia Cesa
Joshua Moeller
Rebecca A. Wingert

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1695380

953 views

Mini Review

Published on 11 Dec 2025

Plakophilin 1 in cancer: context-dependent dualism, subcellular dynamics, and therapeutic targeting

Yu-Mei Huang
Wen-Ling Zhang
Fa-Qing Tang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1703626

965 views

Review

Accepted on 10 Dec 2025

Multidimensional Mechanisms of Quercetin in Diabetic Kidney Disease

Zhaoyuan Gong
Qianzi Che
Bin Liu
Mingzhi Hu
Haili Zhang
Ning Liang
Huizhen Li
Guozhen Zhao
Lijiao Yan
Tian Song

Frontiers in Cell and Developmental Biology

384 views

Original Research

Published on 10 Dec 2025

The impact of methylprednisolone and rituximab on podocyte injury caused by puromycin aminonucleoside

Li Wang
Manman Zhao
Jialiang Zhu
Ran Hua
Ying Zhu
Fang Deng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1504834

999 views

Review

Published on 10 Dec 2025

Stem cell-based strategies for intervertebral disc regeneration in degenerative microenvironments: challenges and solutions

Honglin Wang
Aoshuang Xu
Wei Hua
Junling Mao
Jiyao Zhang
Xiaobo Ma
Lin Lu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1719332

1,881 views

Mini Review

Published on 10 Dec 2025

Exploring the interconnectedness of multiple sclerosis and erectile dysfunction: mechanisms and management strategies

Yongrui Zhang
Hongliang Cao
Lei Wang
Tao Xu
Bo Yuan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1728027

1,157 views

Correction

Published on 10 Dec 2025

Correction: Synaptonemal & CO analyzer: a tool for synaptonemal complex and crossover analysis in immunofluorescence images

Joaquim Soriano
Angela Belmonte-Tebar
Elena de la Casa-Esperon

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1736251

757 views

Original Research

Published on 10 Dec 2025

pH-regulated nuclear F-actin assembly during ferroptosis

Menghao Qiao
Zhipeng Yan
Jiewei Huang
Yu Fang
Kun Xu
Lingbo Cao
Haiying Mai
Na Li
Yanmei Li
Yunmiao Guo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1699698

1,408 views

Review

Published on 10 Dec 2025

Sertoli cells as a hub in testicular development and male reproductive

Xianzhou Feng
Jiahui Tian
Shuaiqi Han
Fei Wen
Yu Li
Shuaihang Zhang
Lidi Ouyang
Zhangtao Hu
Xiaoxu Chen
Jianhong Hu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1693878

2,370 views

Editorial

Published on 10 Dec 2025

Editorial: Ubiquitin proteasome system (UPS) and ubiquitin-independent proteasome-mediated proteolysis (UIPP) crosstalk in development and disease

Michal Sharon
Ralf Stohwasser

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1748172

790 views

13,024 Publications

volumes

Volume 13 - 2025

Low-dose letrozole-HMG regimen reverses letrozole-induced endometrial impairment and improves frozen embryo transfer outcomes

Aging-associated mechanisms and metabolic vulnerabilities in esophageal carcinoma: an integrative review

Image-text guided fundus vessel segmentation via attention mechanism and gated residual learning

Multi-omics analysis reveals a protective role of endogenous proline in sheep oocyte vitrification and its therapeutic application

Establishment of RpHluorin2-expressing cell and its application in monitoring JTC-801-induced alkaliptosis via multi-dimensional fluorescence detection approaches

Cartilage organoids: an emerging platform for novel osteoarthritis therapies

Editorial: Antioxidants in mitigating oxidative stress-induced damage

Effects of high-altitude environments on intervertebral disc degeneration and transcriptome profiling of the nucleus pulposus

Advances in adhesion interfaces of peripheral nerve repair materials: mechanism, classification, evaluation method, and functionalization

The AI-driven blueprint: decoding intervertebral disc repair mechanisms for intelligent biomaterial design

Identification of shared lactylation-related gene signatures between osteoporosis and chronic kidney disease

Knowledge-enhanced AI drives diagnosis of multiple retinal diseases in fundus fluorescein angiography

Single-cell cloning and its approaches

Molecular insights into Atorvastatin’s role in delaying intervertebral disc degeneration

Mathematical modeling reveals cell differentiation processes and progenitor kinetics necessary for proper nephrogenesis

Plakophilin 1 in cancer: context-dependent dualism, subcellular dynamics, and therapeutic targeting

Multidimensional Mechanisms of Quercetin in Diabetic Kidney Disease

The impact of methylprednisolone and rituximab on podocyte injury caused by puromycin aminonucleoside

Stem cell-based strategies for intervertebral disc regeneration in degenerative microenvironments: challenges and solutions

Exploring the interconnectedness of multiple sclerosis and erectile dysfunction: mechanisms and management strategies

Correction: Synaptonemal & CO analyzer: a tool for synaptonemal complex and crossover analysis in immunofluorescence images

pH-regulated nuclear F-actin assembly during ferroptosis

Sertoli cells as a hub in testicular development and male reproductive

Editorial: Ubiquitin proteasome system (UPS) and ubiquitin-independent proteasome-mediated proteolysis (UIPP) crosstalk in development and disease