Frontiers in Cell and Developmental Biology

Editorial

Published on 10 Dec 2025

Editorial: Ubiquitin proteasome system (UPS) and ubiquitin-independent proteasome-mediated proteolysis (UIPP) crosstalk in development and disease

Michal Sharon
Ralf Stohwasser

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1748172

790 views

Review

Published on 10 Dec 2025

The role of astrocytes in ischemic stroke - mechanisms, functions and treatment

Yunlong Wang
Ding Wang
Dongyu Li
Yuewen Ma

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1700564

1,243 views

Review

Published on 10 Dec 2025

Clinical application of PBMCs in breast cancer: detection, treatment evaluation and prognosis

Bo Song
Shixuan Liang
Peng Wu
Xiaomin Li
Qian Gong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1721106

1,146 views

Review

Published on 10 Dec 2025

Sidedness matters: single-cell perspectives on left- and right-sided colorectal cancer

Maria Yanova
Diana Maltseva
Alexander Tonevitsky

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1720996

1,753 views

Review

Published on 09 Dec 2025

Decoding dental mesenchymal stem cells diversity: single-cell transcriptomics maps heterogeneity in molar development

Ruilin Zhang
Leyi Chen
Wanli Xu
Wenan Xu
Buling Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1712688

1,774 views

Hypothesis and Theory

Published on 09 Dec 2025

Carcinogenesis trajectories

Rui Wang
Zhaopeng Yan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1671115

1,377 views

Original Research

Published on 08 Dec 2025

Maternal provisioning and zygotic activation: transcriptomic dynamics of early atlantic halibut (Hippoglossus hippoglossus) embryogenesis

Nils Niepagen
Francesca Bertolini
Leif Berg
Jonna Tomkiewicz
Elin Kjørsvik

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1723170

1,249 views
1 citation

Original Research

Published on 08 Dec 2025

The effect of disulfidptosis induced by glucose starvation in SLC7A11high ovarian cancer cells

Yating Chen
Yu-Hua Ou
Wenjing Shi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608150

1,229 views

Original Research

Published on 05 Dec 2025

Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease

Di Zhang
Qiang Li
Xiaoli Yang
Yongmin Xiong
Shiquan Sun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1687954

1,169 views

Mini Review

Published on 05 Dec 2025

Tumor suppressor function of formyl peptide receptor 1 in gastrointestinal cancers: a focus on the underlying signaling

Maria Marotta
Federica Liotti
Rosa Marina Melillo
Nella Prevete

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1733396

938 views

Original Research

Published on 05 Dec 2025

Proteome profiling of extracellular vesicles-derived from hepatitis B virus-infected hepatocellular carcinoma cell lines identifies PDCD11 as a carrier of viral RNAs

Indrashish Dey
Anusmriti Das
Subhas Das
Soham Saha
Abhijit Chowdhury
Simanti Datta
Soma Banerjee

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1643823

1,927 views

Review

Published on 04 Dec 2025

Dual-faced circRNAs: orchestrating immunosuppression and activation in the lung cancer microenvironment

Junyao Li
Lin Zhang
Yicun Wang
Chunyan Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1706393

1,653 views

Review

Published on 04 Dec 2025

Emerging roles of stress granules in liver diseases: a comprehensive review

Qianyun Zhang
Yun Liu
Junzhe Tang
Ming Li
Qiang Jia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1731227

1,353 views

Original Research

Published on 04 Dec 2025

Quantitative analysis of the effect of ocular rotation on postoperative residual astigmatism in small incision lenticule extraction for myopia correction

Caiyu Liu
Xiaoying Xu
Hao Gu
Chi Wang
Lu Lu
Kaizhen Ye
Yan Zheng
Haiyan Wang
Wei Chen
Meiyan Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1695775

1,091 views

Mini Review

Published on 04 Dec 2025

Evolving frontiers in bladder cancer immunotherapy: integrating BCG, immune checkpoints, viral vectors, nanotechnology, and CAR-based therapies

Anna Di Spirito
Gaia Zuccolotto
Anna Tosi
Sahar Balkhi
Antonio Rosato
Denisa Baci
Lorenzo Mortara

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1719978

1,870 views

Original Research

Published on 04 Dec 2025

Loss of a primary cilia protein ARL13B promotes TGFβ-1 induced EMT of RPE in proliferative vitreoretinopathy via increasing Smad3 expression

Wenjun Sui
Xinqi Ma
Yajun Gong
Kairui Qiu
Miner Yuan
Keli Mao
Xiaobing Qian
Jieting Zeng
Yujie Li
Bingsheng Lou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1661658

1,364 views

Original Research

Published on 03 Dec 2025

Long-chain fatty acid β-oxidation regulates embryonic development by H3K18 acetylation in mice

Kefan Zheng
Hongdi Cui
Ziheng Tang
Entong Song
Qingran Kong
Jiaming Zhang
Hao Li
Qi Zhao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1683028

1,183 views
1 citation

Review

Published on 03 Dec 2025

Restoring metabolic flexibility: targeting organelle interaction networks in the pathogenesis and therapy of MASLD

Yiming Liu
Yue Wang
Jiaying Zhou
Hong Li
Caiyun Liu
Beilei Zhong
Juan Liu
Leiming Liu
Lingling Zhang
Leimin Sun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1718799

2,132 views

Review

Published on 03 Dec 2025

Emerging roles and therapeutic potential of tRNA-Derived small RNAs in reproductive system diseases: a review

Qian Zhou
Minxin He
Min Liu
Guoying Sun
Jian Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1698265

1,860 views
2 citations

Review

Published on 03 Dec 2025

R-loops as a trigger for intra- and extrachromosomal DNA amplification in cancer

Tatyana F. Kovalenko
Amal Abdurazakov
Nadezhda V. Antipova
Mikhail I. Shakhparonov
Marat S. Pavlyukov

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1647255

2,041 views

Original Research

Published on 03 Dec 2025

Comprehensive bioinformatics and in vitro studies reveal the carcinogenic role and molecular basis of endocrine disruptors in prostate cancer

Feng Yu
Bangwei Che
Wei Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1712195

1,698 views

Original Research

Published on 03 Dec 2025

TNF-α exacerbates calcium influx via voltage-gated calcium channels in breast cancer cells: a nanoscale multimodal AFM study

Zhongwei Wang
Qianhui Xu
Huaiwei Zhang
Rongrong Feng
Junmei Chen
Jinsong Wei
Haijian Zhong
Weidong Zhao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1633976

1,160 views

Original Research

Published on 02 Dec 2025

Evaluating the competence of large language models in ophthalmology clinical practice: a multi-scenario quantitative study

Mu-Yang Wei
Yu-Lin Li
Shu-Yan Liu
Guang-Yu Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1704762

1,141 views

Editorial

Published on 02 Dec 2025

Editorial: Cardiac fibroblasts: from development to disease

Silvia C. Hernandez
Thomas Moore-Morris
Adrian Ruiz-Villalba

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1736508

678 views

13,025 Publications

volumes

Volume 13 - 2025

Editorial: Ubiquitin proteasome system (UPS) and ubiquitin-independent proteasome-mediated proteolysis (UIPP) crosstalk in development and disease

The role of astrocytes in ischemic stroke - mechanisms, functions and treatment

Clinical application of PBMCs in breast cancer: detection, treatment evaluation and prognosis

Sidedness matters: single-cell perspectives on left- and right-sided colorectal cancer

Decoding dental mesenchymal stem cells diversity: single-cell transcriptomics maps heterogeneity in molar development

Carcinogenesis trajectories

Maternal provisioning and zygotic activation: transcriptomic dynamics of early atlantic halibut (Hippoglossus hippoglossus) embryogenesis

The effect of disulfidptosis induced by glucose starvation in SLC7A11high ovarian cancer cells

Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease

Tumor suppressor function of formyl peptide receptor 1 in gastrointestinal cancers: a focus on the underlying signaling

Proteome profiling of extracellular vesicles-derived from hepatitis B virus-infected hepatocellular carcinoma cell lines identifies PDCD11 as a carrier of viral RNAs

Dual-faced circRNAs: orchestrating immunosuppression and activation in the lung cancer microenvironment

Emerging roles of stress granules in liver diseases: a comprehensive review

Quantitative analysis of the effect of ocular rotation on postoperative residual astigmatism in small incision lenticule extraction for myopia correction

Evolving frontiers in bladder cancer immunotherapy: integrating BCG, immune checkpoints, viral vectors, nanotechnology, and CAR-based therapies

Loss of a primary cilia protein ARL13B promotes TGFβ-1 induced EMT of RPE in proliferative vitreoretinopathy via increasing Smad3 expression

Long-chain fatty acid β-oxidation regulates embryonic development by H3K18 acetylation in mice

Restoring metabolic flexibility: targeting organelle interaction networks in the pathogenesis and therapy of MASLD

Emerging roles and therapeutic potential of tRNA-Derived small RNAs in reproductive system diseases: a review

R-loops as a trigger for intra- and extrachromosomal DNA amplification in cancer

Comprehensive bioinformatics and in vitro studies reveal the carcinogenic role and molecular basis of endocrine disruptors in prostate cancer

TNF-α exacerbates calcium influx via voltage-gated calcium channels in breast cancer cells: a nanoscale multimodal AFM study

Evaluating the competence of large language models in ophthalmology clinical practice: a multi-scenario quantitative study

Editorial: Cardiac fibroblasts: from development to disease