Frontiers in Cell and Developmental Biology

Original Research

Published on 27 Nov 2025

Hypertensive disorders of pregnancy increase neonatal cerebral regional tissue oxygen saturation in the early postnatal period: partial mediation by preterm birth

Yao Zhang
Tong Yang
Dengjun Liu
Jiaxi Wu
Yanxia Mao
Dapeng Chen
Jun Tang
Yi Yang
Tao Xiong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1682675

856 views

Original Research

Published on 26 Nov 2025

Enhancing preoperative HER2 status classification of invasive breast cancers using machine learning models based on clinicopathological and MRI features: a multicenter study

Suhong Zhao
Zhaohua Li
Yanan Wang
Fang Zhao
Peipei Chen
Guodong Pang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1669651

988 views

Mini Review

Published on 26 Nov 2025

Targeting endothelial cells: the pathological mechanisms and therapeutic innovations in pulmonary arterial hypertension

Tianfei Fan
Longji Li
Yao Wang
Meng Lin
Fengbo Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1690124

1,766 views
2 citations

Original Research

Published on 26 Nov 2025

A machine learning-based predictive model for 48-week hepatitis B surface antigen seroclearance in chronic hepatitis B patients treated with pegylated interferon α-2b: prediction at week 24

Nan Kong
Kaixia Wang
Yiling Wang
Shike Lou
Luocheng Zhou
Tao Wang
Zhili Tan
Lihong Qu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1734654

1,227 views

Original Research

Published on 25 Nov 2025

Doxorubicin induces cardiotoxicity by enhancing autophagy via mTOR signaling in hiPSC- and hESC-derived cardiomyocytes

Minxia Ke
Hao Wang
Kailun Yang
Meng Ji
Nianmin Qi
Yuehong Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1616235

1,557 views

Review

Published on 25 Nov 2025

In-silico pharmacological insights into the therapeutic potential of microRNAs for microplastic-associated cancers

Akmaral Baspakova
Afshin Zare
Nadiar M. Mussin
Nader Tanideh
Kulyash R. Zhilisbayeva
Ramazon Safarzoda Sharoffidin
Roza Suleimenova
Gulden Yelgondina
Akmeiir E. Kaliyeva
Aigerim A. Umbetova

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1699693

1,809 views

Correction

Published on 25 Nov 2025

Correction: Plant-derived extracellular vesicles: an alternative and complementary therapeutic approach for genitourinary tumors

Yuqing Huang
Yunmeng Zhang
Kecheng Lou
Shangzhi Feng
Guoqiang Feng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1741627

644 views

Original Research

Published on 25 Nov 2025

Optimised dissociation and multimodal profiling of prostate cancer stroma reveal fibromuscular cell heterogeneity with clinical correlates

Elisabeth Damisch
Elena Brunner
Lukas Nommensen
Lucy Neumann
Georgios Fotakis
Zlatko Trajanoski
Sieghart Sopper
Georg Schäfer
Martin Puhr
Isabel Heidegger

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1653780

2,312 views

Original Research

Published on 24 Nov 2025

Establishment and transcriptomic characterization of canine organoids from multiple tissues

Christopher Zdyrski
Vojtech Gabriel
Oscar Ospina
Hannah F. Nicholson
Michael Catucci
Bryan J. Melvin
Hannah Wickham
Dipak Kumar Sahoo
Kimberly Dao
Leeann S. Aguilar Meza

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1680376

2,524 views

Original Research

Published on 24 Nov 2025

Mitochondrial AAA+ protease activity uncovers differential sensitivity of Drosophila blood cell lineages to systemic cues

Rajarshi Batabyal
Aman Sharma
Maneesha S. Inamdar

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1606805

1,533 views

Review

Published on 24 Nov 2025

Cis-regulatory elements operating in the trophoblast

Terezia Vcelkova
Paulina A. Latos

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1661952

1,343 views
1 citation

Correction

Published on 24 Nov 2025

Correction: Tumor organoids may be more suitable for clinical personalized chemotherapeutic drug screening in lung adenocarcinoma

Wuyang Yun
Yuyu Li
Yanlei Ge
Xiaoyun Zhang
Huifeng Liu
Wen Chen
Li Xiao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1728870

595 views

Original Research

Published on 24 Nov 2025

Astrocytic gatekeeping of neural circuitry and synaptic balance in an autism mouse model: mechanistic insights beyond Gryllus bimaculatus extract-derived therapy

Haesung Lee
Ngoc Buu Tran
Sook-Jeong Lee

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1677851

1,206 views

Review

Published on 24 Nov 2025

Role of mitochondria-associated membranes (MAMs) in inflammatory signaling: implications for acute lung injury pathogenesis

Huifeng Qian
Guanguan Qiu
Jianguo Xu
Guoping Zheng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1690934

2,260 views

Original Research

Published on 21 Nov 2025

PARP9 drives the malignant progression of pancreatic cancer cells by regulating apoptosis, DNA damage, and multidrug efflux systems

Xing Wang
Xiaolong Liu
Yulan Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1694345

976 views

Review

Published on 21 Nov 2025

Unraveling hematopoietic stem cell ontogeny through single-cell multi-omics approaches

Yan Jia
Sixuan Huo
Fei Wu
Ningning Song
Mei Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1704887

1,754 views

Review

Published on 21 Nov 2025

Extracellular vesicles in reproductive medicine: from “animal-led” to “plant-enabled”

Keying Pan
Wenhan Ju
Yue Wang
Qianwen Zhang
Ruyi Wang
Xingyue Jiang
Shuai Zhao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1718643

1,288 views
1 citation

Original Research

Published on 21 Nov 2025

CRISPR/Cas9-mediated CH2 deletion of Fel d1 triggers transcriptomic reprogramming and disease-associated pathways in feline cells

Lin-Yi Qu
Fu-Shi Quan
Shu-Ming Shi
Zhi-Chao Chi
Jian Chen
Yong-Xun Jin
Ming-Jun Zhang
Il-Keun Kong
Xian-Feng Yu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1716808

1,715 views

Original Research

Published on 20 Nov 2025

Potential diagnostic markers and therapeutic targets for periodontitis with comorbid infective endocarditis based on bioinformatics and experimental analyses

Feng Mei
Wenjie Zhang
Xinlin Wang
Yutong Liu
Xiangyu Zhou
Ting Zhou
Wei Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1725544

1,052 views

Original Research

Published on 20 Nov 2025

Acetylcholine in the gingival epithelium drives the pathogenesis of periodontitis

Shihan Xu
Jiaxin Guo
Shiwen Yang
Bin Cheng
Juan Xia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1701252

1,265 views

Mini Review

Published on 20 Nov 2025

Dendrite glia interactions: lessons from the C. elegans amphid sense organ

Katherine C. Varandas

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1715817

1,947 views

Original Research

Published on 20 Nov 2025

Mitochondrial structure and function in OCRL depleted cells

Ron George Philip
Priyanka Bhatia
Yojet Sharma
Padinjat Raghu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1679675

1,469 views

Original Research

Published on 19 Nov 2025

Zinc transporter ZIP10 supports zinc homeostasis and myoglobin biosynthesis in differentiating C2C12 myoblasts

Geonu Shim
Min Ji Kim
Moon-Suhn Ryu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1691317

1,434 views

Review

Published on 19 Nov 2025

G protein-coupled receptors in prostate cancer: research progress and therapeutic targets

Wei Xiong
Bingpeng Zhou
Jian Shi
Dong Ni
Zhiyong Xiong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1709098

1,463 views

13,029 Publications

volumes

Volume 13 - 2025

Hypertensive disorders of pregnancy increase neonatal cerebral regional tissue oxygen saturation in the early postnatal period: partial mediation by preterm birth

Enhancing preoperative HER2 status classification of invasive breast cancers using machine learning models based on clinicopathological and MRI features: a multicenter study

Targeting endothelial cells: the pathological mechanisms and therapeutic innovations in pulmonary arterial hypertension

A machine learning-based predictive model for 48-week hepatitis B surface antigen seroclearance in chronic hepatitis B patients treated with pegylated interferon α-2b: prediction at week 24

Doxorubicin induces cardiotoxicity by enhancing autophagy via mTOR signaling in hiPSC- and hESC-derived cardiomyocytes

In-silico pharmacological insights into the therapeutic potential of microRNAs for microplastic-associated cancers

Correction: Plant-derived extracellular vesicles: an alternative and complementary therapeutic approach for genitourinary tumors

Optimised dissociation and multimodal profiling of prostate cancer stroma reveal fibromuscular cell heterogeneity with clinical correlates

Establishment and transcriptomic characterization of canine organoids from multiple tissues

Mitochondrial AAA+ protease activity uncovers differential sensitivity of Drosophila blood cell lineages to systemic cues

Cis-regulatory elements operating in the trophoblast

Correction: Tumor organoids may be more suitable for clinical personalized chemotherapeutic drug screening in lung adenocarcinoma

Astrocytic gatekeeping of neural circuitry and synaptic balance in an autism mouse model: mechanistic insights beyond Gryllus bimaculatus extract-derived therapy

Role of mitochondria-associated membranes (MAMs) in inflammatory signaling: implications for acute lung injury pathogenesis

PARP9 drives the malignant progression of pancreatic cancer cells by regulating apoptosis, DNA damage, and multidrug efflux systems

Unraveling hematopoietic stem cell ontogeny through single-cell multi-omics approaches

Extracellular vesicles in reproductive medicine: from “animal-led” to “plant-enabled”

CRISPR/Cas9-mediated CH2 deletion of Fel d1 triggers transcriptomic reprogramming and disease-associated pathways in feline cells

Potential diagnostic markers and therapeutic targets for periodontitis with comorbid infective endocarditis based on bioinformatics and experimental analyses

Acetylcholine in the gingival epithelium drives the pathogenesis of periodontitis

Dendrite glia interactions: lessons from the C. elegans amphid sense organ

Mitochondrial structure and function in OCRL depleted cells

Zinc transporter ZIP10 supports zinc homeostasis and myoglobin biosynthesis in differentiating C2C12 myoblasts

G protein-coupled receptors in prostate cancer: research progress and therapeutic targets