Frontiers in Cellular Neuroscience | Cellular Neuropathology

Original Research

Published on 22 Apr 2025

O6-methylguanine DNA methyltransferase (MGMT) expression in U1242 glioblastoma cells enhances in vitro clonogenicity, tumor implantation in vivo, and sensitivity to alisertib-carboplatin combination treatment

in Cellular Neuropathology

Müge Sak
Brian J. Williams
Andrew J. Hey
Mayur Sharma
Leslie Schier
Megan J. Wilson
Mahatma Ortega
Alyssa I. Lara
Mikaela N. Brentlinger
Norman L. Lehman

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1552015

3,015 views
2 citations

Original Research

Published on 17 Apr 2025

Mitochondrial stress disassembles nuclear architecture through proteolytic activation of PKCδ and Lamin B1 phosphorylation in neuronal cells: implications for pathogenesis of age-related neurodegenerative diseases

in Cellular Neuropathology

Adhithiya Charli
Yuan-Teng Chang
Jie Luo
Bharathi Palanisamy
Emir Malovic
Zainab Riaz
Cameron Miller
Manikandan Samidurai
Gary Zenitsky
Huajun Jin

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1549265

4,102 views
1 citation

Review

Published on 17 Apr 2025

Intestinal injury and changes of the gut microbiota after ischemic stroke

in Cellular Neuropathology

Yang Shen
Jin Wang
Yina Li
Xianhui Kang
Lijuan Gu

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1557746

4,004 views
2 citations

Original Research

Published on 17 Apr 2025

Chronic palmitoylethanolamide administration via slow-release subcutaneous pellets promotes neuroprotection and mitigates neuroinflammation in the Tg2576 mouse model of Alzheimer’s disease

in Cellular Neuropathology

Daniel Tortolani
Davide Decandia
Giacomo Giacovazzo
Lucia Scipioni
Anna Panuccio
Francesca Ciaramellano
Fabiola Eugelio
Federico Fanti
Emanuele Claudio Latagliata
Livia La Barbera

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1571428

4,075 views
3 citations

Systematic Review

Published on 16 Apr 2025

Assessment of mesenchymal stem cells for the treatment of spinal cord injury: a systematic review and network meta-analysis

in Cellular Neuropathology

Runfang Wang
Yiding Wang
Fangning Yan
Jinqing Sun
Tianyu Zhang

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1532219

26,656 views
1 citation

Opinion

Published on 14 Apr 2025

Cases of Creutzfeldt-Jakob disease in young individuals: open questions regarding aetiology

in Cellular Neuropathology

Ilia V. Baskakov

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1571662

7,036 views
1 citation

Original Research

Published on 10 Apr 2025

Genetic mechanisms of dynamic functional connectivity density in diabetic retinopathy brains: a combined transcriptomic and resting-state functional magnetic resonance imaging study

in Cellular Neuropathology

Yu-Lin Zhong
Hao Liu
Xin Huang

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1476038

2,563 views
1 citation

Review

Published on 07 Apr 2025

Interplay between noise-induced sensorineural hearing loss and hypertension: pathophysiological mechanisms and therapeutic prospects

in Cellular Neuropathology

Carola Y. Förster
Sergey Shityakov
Stavros Stavrakis
Verena Scheper
Thomas Lenarz

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1523149

4,859 views
5 citations

Mini Review

Published on 07 Apr 2025

Neuroimmune crosstalk in chronic neuroinflammation: microglial interactions and immune modulation

in Cellular Neuropathology

Ludmila Müller
Svetlana Di Benedetto

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1575022

7,595 views
32 citations

Review

Published on 07 Apr 2025

Blood-brain barrier repair: potential and challenges of stem cells and exosomes in stroke treatment

in Cellular Neuropathology

Xiaochen Fu
Jia Li
Shoujun Yang
Jiapeng Jing
Qinzhi Zheng
Ting Zhang
Zhuo Xu

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1536028

5,390 views
6 citations

Review

Published on 07 Apr 2025

CRISPR/Cas9-Based therapeutics as a promising strategy for management of Alzheimer’s disease: progress and prospects

in Cellular Neuropathology

Mohamad Sultan Khan
Nousheen Qureshi
Rehan Khan
Young-Ok Son
Tariq Maqbool

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1578138

13,390 views
15 citations

Review

Published on 04 Apr 2025

Natural killer cells in multiple sclerosis: foe or friends?

in Cellular Neuropathology

Fatemeh Aghaee
Mohammadreza Abedinpour
Saeid Anvari
Alia Saberi
Amir Fallah
Arash Bakhshi

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1500770

4,234 views
6 citations

Review

Published on 02 Apr 2025

An electrophysiologist’s guide to dorsal horn excitability and pain

in Cellular Neuropathology

Iván Rivera-Arconada
Mark L. Baccei
José A. López-García
Rita Bardoni

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1548252

5,113 views
12 citations

Editorial

Published on 01 Apr 2025

Editorial: Metabolic dysregulation in neurodegenerative diseases

in Cellular Neuropathology

Maria Jimenez-Gonzalez

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1591313

2,288 views
1 citation

Review

Published on 31 Mar 2025

Research progress of DNA methylation on the regulation of substance use disorders and the mechanisms

in Cellular Neuropathology

Ya Liu
Xiao-Qian Wang
Peng Zhang
Abbas Haghparast
Wen-Bin He
Jian-Jun Zhang

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1566001

4,253 views
1 citation

Original Research

Published on 31 Mar 2025

A vascular endothelial cell, neuron, and microglia tri-culture model to study hypertension-related depression

in Cellular Neuropathology

Hongxia Zhao
Lingge Huang
Jian Liu
Min Feng
Yeqian Liu
Hong Li
Shan Gong
Chunming Chen
Shuiqing Zeng
Weiqiong Ren

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1553309

3,971 views
1 citation

Mini Review

Published on 28 Mar 2025

Cell-type specific epigenetic and transcriptional mechanisms in substance use disorder

in Cellular Neuropathology

Bin Wang
Jiale Wang
Nicholas J. Beacher
Da-Ting Lin
Yan Zhang

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1552032

2,750 views

Review

Published on 26 Mar 2025

Studying the mechanisms of neurodegeneration: C. elegans advantages and opportunities

in Cellular Neuropathology

Angie K. Torres
Rodrigo G. Mira
Cristina Pinto
Nibaldo C. Inestrosa

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1559151

7,156 views
6 citations

Original Research

Published on 12 Mar 2025

Association between cognitive functioning and microbiota-gut-brain axis mediators in a memory clinic population

in Cellular Neuropathology

Claudio Singh Solorzano
Cristina Festari
Peppino Mirabelli
Elisa Mombelli
Luigi Coppola
Delia Luongo
Daniele Naviglio
Andrea Soricelli
Giulia Quattrini
Marco Salvatore

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1550333

3,324 views
2 citations

Original Research

Published on 11 Mar 2025

Riboflavin transporter deficiency: AAV9-SLC52A2 gene therapy as a new therapeutic strategy

in Cellular Neuropathology

Cecilia Mei
Valentina Magliocca
Xin Chen
Keith Massey
Anai Gonzalez-Cordero
Steven J. Gray
Marco Tartaglia
Enrico Silvio Bertini
Stefania Corti
Claudia Compagnucci

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1523773

3,609 views
3 citations

Editorial

Published on 11 Mar 2025

Editorial: The role of inflammation in neurodegenerative and psychiatric disorders

in Cellular Neuropathology

Dirk M. Hermann
Mingyue Zhang
Anfei Huang
Zenghui Teng

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1574274

1,667 views

Perspective

Published on 11 Mar 2025

Thinning of originally-existing, mature myelin represents a nondestructive form of myelin loss in the adult CNS

in Cellular Neuropathology

Min Li Lin
Wensheng Lin

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1565913

1,793 views

Review

Published on 10 Mar 2025

PTEN: a new dawn in Parkinson’s disease treatment

in Cellular Neuropathology

Xinghuang Yang
Tianqi Liu
Hong Cheng

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1497555

3,656 views
2 citations

Original Research

Published on 05 Mar 2025

Paving the way for better ototoxicity assessments in cisplatin therapy using more reliable animal models

in Cellular Neuropathology

Vijayprakash Manickam
Marisa Zallocchi

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1552051

2,118 views
2 citations

2,079 articles

articles

O6-methylguanine DNA methyltransferase (MGMT) expression in U1242 glioblastoma cells enhances in vitro clonogenicity, tumor implantation in vivo, and sensitivity to alisertib-carboplatin combination treatment

Mitochondrial stress disassembles nuclear architecture through proteolytic activation of PKCδ and Lamin B1 phosphorylation in neuronal cells: implications for pathogenesis of age-related neurodegenerative diseases

Intestinal injury and changes of the gut microbiota after ischemic stroke

Chronic palmitoylethanolamide administration via slow-release subcutaneous pellets promotes neuroprotection and mitigates neuroinflammation in the Tg2576 mouse model of Alzheimer’s disease

Assessment of mesenchymal stem cells for the treatment of spinal cord injury: a systematic review and network meta-analysis

Cases of Creutzfeldt-Jakob disease in young individuals: open questions regarding aetiology

Genetic mechanisms of dynamic functional connectivity density in diabetic retinopathy brains: a combined transcriptomic and resting-state functional magnetic resonance imaging study

Interplay between noise-induced sensorineural hearing loss and hypertension: pathophysiological mechanisms and therapeutic prospects

Neuroimmune crosstalk in chronic neuroinflammation: microglial interactions and immune modulation

Blood-brain barrier repair: potential and challenges of stem cells and exosomes in stroke treatment

CRISPR/Cas9-Based therapeutics as a promising strategy for management of Alzheimer’s disease: progress and prospects

Natural killer cells in multiple sclerosis: foe or friends?

An electrophysiologist’s guide to dorsal horn excitability and pain

Editorial: Metabolic dysregulation in neurodegenerative diseases

Research progress of DNA methylation on the regulation of substance use disorders and the mechanisms

A vascular endothelial cell, neuron, and microglia tri-culture model to study hypertension-related depression

Cell-type specific epigenetic and transcriptional mechanisms in substance use disorder

Studying the mechanisms of neurodegeneration: C. elegans advantages and opportunities

Association between cognitive functioning and microbiota-gut-brain axis mediators in a memory clinic population

Riboflavin transporter deficiency: AAV9-SLC52A2 gene therapy as a new therapeutic strategy

Editorial: The role of inflammation in neurodegenerative and psychiatric disorders

Thinning of originally-existing, mature myelin represents a nondestructive form of myelin loss in the adult CNS

PTEN: a new dawn in Parkinson’s disease treatment

Paving the way for better ototoxicity assessments in cisplatin therapy using more reliable animal models