Frontiers in Chemical Biology | Bioinorganic Chemistry

Review

Published on 10 Feb 2026

Zinc-dependent aminopeptidases: new perspectives on structure, function, and biomedical applications

in Bioinorganic Chemistry

Saleem Bhat

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1752191

459 views

Original Research

Published on 05 Feb 2026

Design, synthesis, reactivity, and biological activity of nitroimidazole derivatives and their copper(II) coordination compounds

in Bioinorganic Chemistry

Walter Fugarolas
Lorena Reyes-Carmona
Bruno Landeros-Rivera
Argelia Almaguer-Flores
Norah Barba-Behrens

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1736242

454 views

Original Research

Accepted on 04 Feb 2026

Ligand-directed assembly of an iminodiacetate-hybridized molybdenum-red isopolyoxomolybdate MoV10MoVI3

in Bioinorganic Chemistry

Ingrid Gregorovic
Emir Al-Sayed
Nadiia I. Gumerova
Judith Füllborn-Ott
Ingo Ott
Gerald Giester
Annette Rompel

Frontiers in Chemical Biology

Original Research

Published on 30 Jan 2026

Redox potential fine tuning of ferrocene-peptide conjugates

in Bioinorganic Chemistry

Alessia Difino
Barbara Biondi
Annalisa Bisello
Roberta Cardena
Luana Lastella
Marko Šimić
Beatrice Calderaro
Fernando Formaggio
Marzio Rancan
Saverio Santi

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1736812

408 views

Mini Review

Published on 30 Jan 2026

Ferritin-metallodrugs nanocomposites: light and shadow of drugs loading methods

in Bioinorganic Chemistry

Rosanna Lucignano
Giarita Ferraro

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1740075

284 views

Perspective

Published on 28 Jan 2026

Protein metalation by anticancer metal-based drugs revealed through the integration of ESI-MS and XRD measurements. State of the art and open issues

in Bioinorganic Chemistry

Antonello Merlino
Tiziano Marzo
Luigi Messori

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1758486

299 views

Mini Review

Published on 22 Jan 2026

Anticancer drugs based on metal complexes of 2-imine-8-hydroxyquinolines

in Bioinorganic Chemistry

Leonor Côrte-Real
Nádia Ribeiro
Isabel Correia

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1734289

417 views

Perspective

Published on 15 Jan 2026

From simple to complex: multiscale modeling of metal-mediated protein interactions to uncover mechanistic insights into the action of inorganic drugs

in Bioinorganic Chemistry

Lorenzo Chiaverini
Lidia Ciccone
Alessandro Marrone
Luca Famlonga
Davide Piroddu
Nicolò Tonali
Iogann Tolbatov
Jürgen Gailer
Tiziano Marzo
Luigi Messori

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1764819

485 views

Review

Published on 12 Jan 2026

Receptor-targeted technetium-99m radiopharmaceuticals: increasing access to molecular imaging in healthcare

in Bioinorganic Chemistry

Michelle T. Ma

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1729615

644 views

Perspective

Published on 05 Jan 2026

Tailoring LC approaches to address the chemical biology of toxic metals in humans

in Bioinorganic Chemistry

Jürgen Gailer

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1729141

343 views

Mini Review

Published on 19 Dec 2025

The importance of ferric reductases for iron uptake in humans

in Bioinorganic Chemistry

Hitomi Sawai

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1724624

1,110 views

Mini Review

Published on 20 Oct 2025

Metals in medicine: unlocking new avenues for neurodegenerative disease treatment

in Bioinorganic Chemistry

Kuan Teng Tan
Kok Whye Cheong
Lai Chun Wong
Hélène C. Bertrand
Nurul Huda Abd Karim
Yie Kie Chong
May Lee Low

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1696058

2,113 views

Original Research

Published on 17 Oct 2025

Quantifying antioxidant activity of hydrophobic compounds using metal-mediated DNA damage

in Bioinorganic Chemistry

Andrea A. E. Gaertner
Nathan R. Perron
Heeren M. G. Anderholm
Daniel C. Whitehead
Julia L. Brumaghim

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1677610

1,070 views

Perspective

Published on 29 Sep 2025

X-ray structures of metal-protein adducts at body temperature: concepts, examples and perspectives

in Bioinorganic Chemistry

Antonello Merlino

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1670177

892 views

Editorial

Published on 19 Sep 2025

Editorial: Linking chemistry to biology and medicine via metal ions: developed from the 16th international symposium on applied bioinorganic chemistry

in Bioinorganic Chemistry

Christina N. Banti
Debbie C. Crans
Ana Maria Da Costa Ferreira
Sotiris K. Hadjikakou

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1695257

1,249 views

Perspective

Published on 04 Sep 2025

Lessons from metals-containing drugs in diagnostic, and theranostic applications for future development of metal-containing non-conventional therapeutics: vanadium compounds for intratumor administration

in Bioinorganic Chemistry

Adam R. Miller
Debbie C. Crans

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1639340

1,876 views
1 citation

Original Research

Published on 14 Aug 2025

Preliminary investigation of Ru(II) complexes bearing nile red chromophores for photodynamic therapy

in Bioinorganic Chemistry

Claire Condon
Oriol Careta-Borràs
Judit Fodor
Amani B. Al Riyami
Xiao Xiao
Jianzhang Zhao
Carme Nogués
Sylvia M. Draper

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1620562

1,513 views

Original Research

Published on 12 Aug 2025

Carboxymethyl cellulose hydrogel doped with zinc-aspirinate as a multifunctional material: photoprotection, epithelial regeneration, and biocompatibility

in Bioinorganic Chemistry

Christina N. Banti
Fotakis Lezos
Antonios Hatzidimitriou
Sotiris K. Hadjikakou

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1639096

1,511 views

Original Research

Published on 17 Jun 2025

How vanadium and manganese compounds impact cardiac mitochondrial function

in Bioinorganic Chemistry

Connor C. Dolan
Luke A. Whitcomb
Edgar Del Carpio
Lilliana Rose
Adam J. Chicco
Debbie C. Crans

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1602602

2,090 views

Editorial

Published on 03 Apr 2025

Editorial: New developments in bioinorganic and bioorganic chemistry

in Bioinorganic Chemistry

Isabel Correia
Sylvia M. Draper

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1586841

1,868 views

Original Research

Published on 03 Feb 2025

Reactivity in cell culture medium and in vitro anticancer activity of 3,5-di-tert-butylcatechol: link to metal-catechol interactions

in Bioinorganic Chemistry

Aviva Levina
Debbie C. Crans
Peter A. Lay

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1547323

1,886 views

Review

Published on 20 Dec 2024

Cysteine-rich zinc finger proteins and the nuclear factor kappa-B pathway

in Bioinorganic Chemistry

Andrew T. Stoltzfus
Sarah L. J. Michel

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1503390

2,298 views
1 citation

Original Research

Published on 11 Oct 2024

Molecular interactions at the interface: polyoxometalates of the Anderson-Evans type and lipid membranes

in Bioinorganic Chemistry

Alina A. Pashkovskaya
Nadiia I. Gumerova
Annette Rompel
Elena E. Pohl

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1454558

2,876 views
1 citation

Original Research

Published on 06 Sep 2024

Exploring polyoxometalate speciation: the interplay of concentration, ionic strength, and buffer composition

in Bioinorganic Chemistry

Maja Ždrnja
Nadiia I. Gumerova
Annette Rompel

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1444359

3,341 views
1 citation

35 articles

articles

Zinc-dependent aminopeptidases: new perspectives on structure, function, and biomedical applications

Design, synthesis, reactivity, and biological activity of nitroimidazole derivatives and their copper(II) coordination compounds

Ligand-directed assembly of an iminodiacetate-hybridized molybdenum-red isopolyoxomolybdate MoV10MoVI3

Redox potential fine tuning of ferrocene-peptide conjugates

Ferritin-metallodrugs nanocomposites: light and shadow of drugs loading methods

Protein metalation by anticancer metal-based drugs revealed through the integration of ESI-MS and XRD measurements. State of the art and open issues

Anticancer drugs based on metal complexes of 2-imine-8-hydroxyquinolines

From simple to complex: multiscale modeling of metal-mediated protein interactions to uncover mechanistic insights into the action of inorganic drugs

Receptor-targeted technetium-99m radiopharmaceuticals: increasing access to molecular imaging in healthcare

Tailoring LC approaches to address the chemical biology of toxic metals in humans

The importance of ferric reductases for iron uptake in humans

Metals in medicine: unlocking new avenues for neurodegenerative disease treatment

Quantifying antioxidant activity of hydrophobic compounds using metal-mediated DNA damage

X-ray structures of metal-protein adducts at body temperature: concepts, examples and perspectives

Editorial: Linking chemistry to biology and medicine via metal ions: developed from the 16th international symposium on applied bioinorganic chemistry

Lessons from metals-containing drugs in diagnostic, and theranostic applications for future development of metal-containing non-conventional therapeutics: vanadium compounds for intratumor administration

Preliminary investigation of Ru(II) complexes bearing nile red chromophores for photodynamic therapy

Carboxymethyl cellulose hydrogel doped with zinc-aspirinate as a multifunctional material: photoprotection, epithelial regeneration, and biocompatibility

How vanadium and manganese compounds impact cardiac mitochondrial function

Editorial: New developments in bioinorganic and bioorganic chemistry

Reactivity in cell culture medium and in vitro anticancer activity of 3,5-di-tert-butylcatechol: link to metal-catechol interactions

Cysteine-rich zinc finger proteins and the nuclear factor kappa-B pathway

Molecular interactions at the interface: polyoxometalates of the Anderson-Evans type and lipid membranes

Exploring polyoxometalate speciation: the interplay of concentration, ionic strength, and buffer composition