Frontiers in Chemistry

Original Research

Published on 22 Aug 2025

Natural product Erianin: mitigating FOLFOX toxicity and enhancing against colorectal cancer

in Medicinal and Pharmaceutical Chemistry

Fuqin Yang
Zeqiao Li
Haishan Zhang
Mingxiao Zhang
Zhenwei He
Xiaoqin Zheng
Yingru Zhu
Pei Long
Ruirui Ding
Zhengbin Lin

Frontiers in Chemistry

doi 10.3389/fchem.2025.1650197

3,990 views
1 citation

Original Research

Published on 21 Aug 2025

A fluorescent probe with a vanillin–pyridine–imidazole core structure for carboxylesterase detection in macrophage polarization during bone homeostasis

in Chemical Biology

Hailong Xia
Xianghe Wang
Weichun Huang
Xindong Jiang
Xionggao Han
Chaoyue Wang

Frontiers in Chemistry

doi 10.3389/fchem.2025.1666238

2,260 views

Opinion

Published on 21 Aug 2025

Are basic and lipophilic chain groups highly required in leishmanicidal quinolines to favor the phagolysosome accumulation?

in Medicinal and Pharmaceutical Chemistry

Angel H. Romero

Frontiers in Chemistry

doi 10.3389/fchem.2025.1655979

1,431 views
1 citation

Original Research

Published on 20 Aug 2025

Unveiling the material basis of Shenshuaifu granule and its therapeutic mechanism in chronic renal failure: a combined approach of high-resolution mass spectrometry and in silico technology

in Analytical Chemistry

Qingbao Huang
Leyao Xian
Xiansheng Song
Dawei Zou
Junqi Chen
Yue Chen
Wanquan Li
Shangbin Zhang
Huichao Liang

Frontiers in Chemistry

doi 10.3389/fchem.2025.1563598

2,211 views

Perspective

Published on 19 Aug 2025

Blue energy recovery in the Atacama Desert using electrochemical ion pumping devices: a Chilean perspective on salinity gradient energy

in Electrochemistry

Felipe M. Galleguillos Madrid
Sebastián Salazar-Avalos
Markus Bergendahl
Javier Quispe
Norman Toro
Galvarino Casanueva-Yáñez
Alvaro Soliz

Frontiers in Chemistry

doi 10.3389/fchem.2025.1659479

2,886 views

Original Research

Published on 18 Aug 2025

QSPR graph model to explore physicochemical properties of potential antiviral drugs of dengue disease through novel coloring-based topological indices

in Theoretical and Computational Chemistry

C. Yogalakshmi
B. J. Balamurugan

Frontiers in Chemistry

doi 10.3389/fchem.2025.1599715

5,825 views
2 citations

Editorial

Published on 14 Aug 2025

Editorial: Magnetic nanoparticles for biomedical imaging and therapy applications

in Nanoscience

Juan Gallo
Graeme J. Stasiuk
Anna Roig
Juan Pellico

Frontiers in Chemistry

doi 10.3389/fchem.2025.1670850

1,827 views

Review

Published on 14 Aug 2025

Organic functionality in responsive paramagnetic nanostructures

in Nanoscience

Anna M. Duncan
Connor M. Ellis
James P. Smith
Lillian Leutloff
Matthew J. Langton
Jason J. Davis

Frontiers in Chemistry

doi 10.3389/fchem.2025.1605538

2,714 views

Original Research

Published on 13 Aug 2025

Critical assessment of copper-alginate hydrogel beads as recyclable and heterogeneous catalysts for aqueous azide‒alkyne cycloaddition

in Green and Sustainable Chemistry

Yanina Moglie
Eduardo Buxaderas
Agoney González Cabrera
David Díaz Díaz

Frontiers in Chemistry

doi 10.3389/fchem.2025.1644592

3,451 views
1 citation

Editorial

Published on 12 Aug 2025

Editorial: Applications of nanomaterials for novel thermotherapy

in Nanoscience

S. Manjura Hoque
Chandan Srivastava
A. K. M. Akhter Hossain
Navid B. Saleh

Frontiers in Chemistry

doi 10.3389/fchem.2025.1656509

1,302 views

Original Research

Published on 11 Aug 2025

Discovery of compound 1105486 as a selective inhibitor of B4GALT1: potential for pancreatic cancer therapy

in Medicinal and Pharmaceutical Chemistry

Xu Yunyun
Mou Yiping

Frontiers in Chemistry

doi 10.3389/fchem.2025.1651402

3,165 views

Original Research

Published on 08 Aug 2025

Formulation development, characterization, and optimization of Eudragit–cinnamon essential oil-based nanoplatform and its efficacy against resistant bacteria

in Nanoscience

Touseef Nawaz
Niamat Ullah
Muhammad Ali
Safia Obaidur Rab
Irfan Ahmad
Rabia Baloch
Sadia Chaman
Kifayat Ullah Shah
Adnan Amin

Frontiers in Chemistry

doi 10.3389/fchem.2025.1555449

2,458 views

Original Research

Published on 08 Aug 2025

Discovery of N′-(1-(coumarin-3-yl)ethylidene)benzenesulfonohydrazide as a novel wound healing enhancer: synthesis, biological assessment, and molecular modeling

in Medicinal and Pharmaceutical Chemistry

Eman F. Khaleel
Heba Abdelmegeed
Abdel-Razik H. Abdel-Razik
Manal S. Ebaid
Ninh The Son
Nguyen Xuan Ha
Hoda Atef Abdelsattar Ibrahim
Mohamed A. Abdelrahman
Abdelsamed I. Elshamy
Jarosław Dziadek

Frontiers in Chemistry

doi 10.3389/fchem.2025.1621717

2,528 views
1 citation

Correction

Published on 07 Aug 2025

Correction: Investigation of illicit pregabalin in seized samples from Saudi Arabia

in Analytical Chemistry

Frontiers Production Office

Frontiers in Chemistry

doi 10.3389/fchem.2025.1674670

1,396 views

Original Research

Published on 07 Aug 2025

A naked-eye biosensing system based on one-pot RPA-CRISPR/Cas12a driver G4-hemin self-assembly for Mycobacterium tuberculosis

in Analytical Chemistry

Ting Yuan
Jianbo Yuan
Jian Huang
Nana Li
Huan Cai
Yan Yang
Juan Li
Rui Chen
Xun Min

Frontiers in Chemistry

doi 10.3389/fchem.2025.1631086

2,849 views
1 citation

Original Research

Published on 07 Aug 2025

Engineered LDH-alginate composite hydrogel columns for selective heavy metal removal

in Green and Sustainable Chemistry

Hualai Hao

Frontiers in Chemistry

doi 10.3389/fchem.2025.1649831

2,649 views
3 citations

Original Research

Published on 07 Aug 2025

Chromatographic analysis and monitoring of fault gases in substation using ZIF-8 coated capillary column

in Analytical Chemistry

Hua Mao
Yan Wang
Jie Wang
Zeyao Ma
Yalong Xia
Xiaoliang Zeng
Shihong Hu
Xinsheng Lan
Fangqiang Wang
Lin Zhou

Frontiers in Chemistry

doi 10.3389/fchem.2025.1618268

1,880 views
2 citations

Original Research

Published on 04 Aug 2025

Predict potential pharmacological mechanisms of Ling-gui-Zhu-gan Decoction in treating unstable angina pectoris using liquid chromatography-mass spectrometry and network pharmacology

in Analytical Chemistry

Xiaopeng Li
Tan Xue
Panpan Zhang
Fengyu Dong
Han Li
Jing Yao
Haiying Huang
Lizhuang Zhang
Ruixin Liu

Frontiers in Chemistry

doi 10.3389/fchem.2025.1649538

2,482 views
1 citation

Mini Review

Published on 04 Aug 2025

Revolutionizing organic synthesis through green chemistry: metal-free, bio-based, and microwave-assisted methods

in Green and Sustainable Chemistry

Sayani Banerjee
Sakthi Periyasamy
Kathiravan Muthukumaradoss
Priya Deivasigamani
Venkatesan Saravanan

Frontiers in Chemistry

doi 10.3389/fchem.2025.1656935

8,957 views
6 citations

Original Research

Published on 04 Aug 2025

Multifractal based topological characterization of perovskite crystal and predictive analysis on its physical properties

in Theoretical and Computational Chemistry

K. Yogalakshmi
D. Easwaramoorthy

Frontiers in Chemistry

doi 10.3389/fchem.2025.1639522

2,086 views

Original Research

Published on 01 Aug 2025

Citrus aurantifolia essential oil: antiaging potential through integrated in vitro and in silico studies

in Medicinal and Pharmaceutical Chemistry

Yasmin A. Elkhawas
Mahmoud A. El Hassab
Omkulthom Al kamaly
Ahmed T. Negmeldin
Taghreed A. Majrashi
Wagdy M. Eldehna
Nada M. Mostafa

Frontiers in Chemistry

doi 10.3389/fchem.2025.1577871

3,788 views
1 citation

Original Research

Published on 31 Jul 2025

Design and synthesis of 3,4-seco-Lupane triterpene derivatives: targeting tumor angiogenesis and inducing apoptosis in triple-negative breast cancer

in Medicinal and Pharmaceutical Chemistry

Chunyu Gao
Hongbo Teng
Wenxin Zhang
Yaru Zhao
Chunguo Cui
Zerbo Patrice
Liyan Wang
Yan Zhao

Frontiers in Chemistry

doi 10.3389/fchem.2025.1630939

2,631 views

Correction

Published on 29 Jul 2025

Correction: Integrative computational approaches identify haptoglobin inhibitors to modulate erythrocyte sedimentation rate in trauma-linked inflammatory and haematological malignancies

in Theoretical and Computational Chemistry

Abdulaziz H. Al Khzem
Shaban Ahmad

Frontiers in Chemistry

doi 10.3389/fchem.2025.1662748

1,065 views

Original Research

Published on 28 Jul 2025

In silico design of novel dihydropteridone derivatives with oxadiazoles as potent inhibitors of MCF-7 breast cancer cells

in Medicinal and Pharmaceutical Chemistry

Mourad Aloui
Mohamed El fadili
Mohammed Er-rajy
Somdutt Mujwar
Hatem A. Abuelizz
Sara Er-rahmani
Elhalaoui Menana

Frontiers in Chemistry

doi 10.3389/fchem.2025.1590593

2,348 views
1 citation