Frontiers in Chemistry

Original Research

Published on 11 Jun 2025

Two-dimensional QSAR-driven virtual screening for potential therapeutics against Trypanosoma cruzi

in Medicinal and Pharmaceutical Chemistry

Naseer Maliyakkal
Sunil Kumar
Ratul Bhowmik
Harish Chandra Vishwakarma
Prabha Yadav
Bijo Mathew

Frontiers in Chemistry

doi 10.3389/fchem.2025.1600945

980 views

Review

Published on 11 Jun 2025

The role of intrinsically disordered regions of SARS-CoV-2 nucleocapsid and non-structural protein 1 proteins

in Chemical Biology

Getasew Shitaye
Nataliia Ventserova
Gianluca D’Abrosca
Martina Dragone
Eunice Wairimu Maina
Roberto Fattorusso
Rosa Iacovino
Luigi Russo
Carla Isernia
Gaetano Malgieri

Frontiers in Chemistry

doi 10.3389/fchem.2025.1597656

1,580 views

Original Research

Published on 11 Jun 2025

Effect of acid washing and torrefaction combined pretreatment on the properties of waste tobacco stem biomass and the quality of pyrolysis bio-oil

in Green and Sustainable Chemistry

Anni Wang
Jianhang Hu
Long Zhang
Hua Wang

Frontiers in Chemistry

doi 10.3389/fchem.2025.1603584

709 views

Original Research

Published on 10 Jun 2025

Rapid GC-MS method for screening seized drugs in forensic investigations: optimization and validation

in Analytical Chemistry

Asma M. Askar
Auhood Y. Al Ali
Meera K. Khalifa
Ali A. Salem
Buthaina M. Alkhuwaildi
Iltaf Shah

Frontiers in Chemistry

doi 10.3389/fchem.2025.1559279

1,339 views

Original Research

Published on 10 Jun 2025

Engineering the mechanical characteristics of regenerated silk fibroin materials: the impact of chemical and physical modification strategies

in Polymer Chemistry

Haitao Guan
Fang Ding
Ye Xue
Jinli Zhao

Frontiers in Chemistry

doi 10.3389/fchem.2025.1606995

858 views

Mini Review

Published on 10 Jun 2025

Atomistic simulation of olefin polymerization reaction by organometallic catalyst: significant role of microscopic structural dynamics of (pyridylamido) Hf(IV) complex in catalytic reactivity

in Theoretical and Computational Chemistry

Kentaro Matsumoto
Nana Misawa
Shuhei Kanesato
Masataka Nagaoka

Frontiers in Chemistry

doi 10.3389/fchem.2025.1618025

958 views

Original Research

Accepted on 09 Jun 2025

Formulation Development, Characterization and Optimization of Eudragit-Cinnamon Essential Oil Based Nanoplatform and its efficacy against Resistant Bacteria

in Nanoscience

Dr. Adnan Amin
Tauseef nawaz
Niamat Ullah
Muhammad Ali
Safia Obaidur Rab
Irfan Ahmad
Rabia Baloch
Sadia Chaman
Kifayatullah Shah

Frontiers in Chemistry

doi 10.3389/fchem.2025.1555449

263 views

Original Research

Accepted on 09 Jun 2025

Platinum-group metal half half-sandwich complexes of 1-(α-D-glucopyranosyl)-4-hetaryl-1,2,3-triazoles: synthesis, solution equilibrium studies and investigation of their anticancer and antimicrobial activities

in Chemical Biology

Alshimaa I Zaki
Adrienn Sipos
István Kacsir
Nóra Ildikó Kovács
Éva Kerekes
Evelin Szoták
Csongor Freytag
Máté Demény
István Révész
Péter Buglyó

Frontiers in Chemistry

doi 10.3389/fchem.2025.1619991

374 views

Original Research

Published on 09 Jun 2025

HIF1A acts as target of XiHuang Pill in the treatment of papillary thyroid cancer by regulating dedifferentiation

in Medicinal and Pharmaceutical Chemistry

Xu-Zhe Yu
Wei-Li Zhu
Hua-Chun Qian
Chun-Jiang Sun

Frontiers in Chemistry

doi 10.3389/fchem.2025.1607067

1,081 views

Correction

Published on 09 Jun 2025

Correction: Exploring the therapeutic mechanism of curcumin in spinal cord injury treatment based on network pharmacology, molecular dynamics simulation, and experimental validation

in Medicinal and Pharmaceutical Chemistry

Yongzhi He
Jiachun Lu
Yushan Luo
Rizhao Pang
Xiaoming Hu
Lijuan Ding
Hua Xiao
Yunyun Wang
Wenchun Wang

Frontiers in Chemistry

doi 10.3389/fchem.2025.1636136

753 views

Original Research

Published on 09 Jun 2025

Integrated computational and experimental identification of N-[(1H-1,2,4-triazol-3-yl)phenyl]-1-(1H-pyrazolo[3,4-b]pyridin-3-yl)methanamide as a potent and selective TIM-3 inhibitor for NSCLC immunotherapy

in Medicinal and Pharmaceutical Chemistry

Xinxin Ying
Yangyong Lou
Yueming Wu
Weiwei Hu

Frontiers in Chemistry

doi 10.3389/fchem.2025.1622511

1,082 views

Perspective

Published on 06 Jun 2025

Non-covalent interactions in MOFs: a quantum approach to gas adsorption and molecular encapsulation

in Porous Crystalline Networks

Erika Medel
Rubicelia Vargas

Frontiers in Chemistry

doi 10.3389/fchem.2025.1579977

1,318 views

Original Research

Published on 06 Jun 2025

Understanding mechanisms of Polygonatum sibiricum-derived exosome-like nanoparticles against breast cancer through an integrated metabolomics and network pharmacology analysis

in Analytical Chemistry

Tingwen Ming
Yang Yang
Bing Shang
Zhihao Li
Fangling Ren
Lun Wu
Shuya Zhang
Jun Zhu
Qinhua Chen
Jingjian Liu

Frontiers in Chemistry

doi 10.3389/fchem.2025.1559758

1,499 views

Original Research

Published on 05 Jun 2025

Vineyard pruning-wood waste valorisation: sustainable extraction of bioactive compounds

in Green and Sustainable Chemistry

Elisabetta Tumminelli
Valeria Cavalloro
Chiara Ingrà
Alessandra Ferrandino
Alessio Porta
Giorgio Marrubini
Emanuela Martino
Daniela Rossi
Simona Collina

Frontiers in Chemistry

doi 10.3389/fchem.2025.1597833

1,182 views

Mini Review

Published on 05 Jun 2025

Effects of fluorine modification on the photocatalytic hydrogen production performance of TiO2

in Green and Sustainable Chemistry

Jie Hu
Xianhao Shan
Shan Wu
Pengfei Sun
Zhengyuan Gao
Zhong Ren
Xiangchao Feng
Shuai Wang

Frontiers in Chemistry

doi 10.3389/fchem.2025.1621188

1,163 views

Original Research

Published on 04 Jun 2025

Study on multi-scale oil displacement mechanism polymer/nanoparticle composite flooding

in Polymer Chemistry

Bei Wei
Ningyu Zheng
Yu Xue
Jian Hou
Yongsheng Liu
Zhixin Guo
Xuwen Qin
Qingjun Du

Frontiers in Chemistry

doi 10.3389/fchem.2025.1605416

795 views