Frontiers in Chemistry | Medicinal and Pharmaceutical Chemistry

Original Research

Published on 10 May 2024

Design and synthesis of new dihydropyrimidine/sulphonamide hybrids as promising anti-inflammatory agents via dual mPGES-1/5-LOX inhibition

in Medicinal and Pharmaceutical Chemistry

Lamya H. Al-Wahaibi
Ali M. Elshamsy
Taha F. S. Ali
Bahaa G. M. Youssif
S. Bräse
Mohamed Abdel-Aziz
Nawal A. El-Koussi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1387923

4,560 views
6 citations

Review

Published on 01 May 2024

Application and progress of new technologies and new materials in the treatment of pathological scar

in Medicinal and Pharmaceutical Chemistry

Yining Liu
Sisi Wang
Fan Yang
Xuepeng Wang
Jierui Zhang
Xinkun Han
Xipeng Zhang
Zhiguo Wang

Frontiers in Chemistry

doi 10.3389/fchem.2024.1389399

4,904 views
6 citations

Original Research

Published on 29 Apr 2024

Modulation in serum and hematological parameters as a prognostic indicator of COVID-19 infection in hypertension, diabetes mellitus, and different cardiovascular diseases

in Medicinal and Pharmaceutical Chemistry

Muhammad Ishtiaq Jan
Riaz Anwar Khan
Naeem Khan
Syed Muhammad Iftikhar
Sajid Ali
M. I. Khan
Saima Gul
Umar Nishan
Tahir Ali
Riaz Ullah

Frontiers in Chemistry

doi 10.3389/fchem.2024.1361082

1,748 views
2 citations

Editorial

Published on 24 Apr 2024

Editorial: Recent progress in drug delivery technologies for advanced pharmaceutics

in Medicinal and Pharmaceutical Chemistry

Bing Guo
Tingting Peng
Qinglian Hu
Ruirui Qiao

Frontiers in Chemistry

doi 10.3389/fchem.2024.1413056

1,329 views

Review

Published on 18 Apr 2024

Fragment-based drug discovery for disorders of the central nervous system: designing better drugs piece by piece

in Medicinal and Pharmaceutical Chemistry

Bill W. G. L. Chan
Nicholas B. Lynch
Wendy Tran
Jack M. Joyce
G. Paul Savage
Wim Meutermans
Andrew P. Montgomery
Michael Kassiou

Frontiers in Chemistry

doi 10.3389/fchem.2024.1379518

7,205 views
8 citations

Original Research

Published on 18 Apr 2024

Isolation of quinic acid from dropped Citrus reticulata Blanco fruits: its derivatization, antibacterial potential, docking studies, and ADMET profiling

in Medicinal and Pharmaceutical Chemistry

Heena
Sonia Kaushal
Vishaldeep Kaur
Harsh Panwar
Purshotam Sharma
Raman Jangra

Frontiers in Chemistry

doi 10.3389/fchem.2024.1372560

5,398 views
8 citations

Correction

Published on 17 Apr 2024

Corrigendum: Developments in 177Lu-based radiopharmaceutical therapy and dosimetry

in Medicinal and Pharmaceutical Chemistry

Siju C. George
E. James Jebaseelan Samuel

Frontiers in Chemistry

doi 10.3389/fchem.2024.1410803

854 views
1 citation

Editorial

Published on 17 Apr 2024

Editorial: Medicinal chemistry of active pharmaceutical ingredients of drug products

in Medicinal and Pharmaceutical Chemistry

Mohd Imran
Qasim M. Alhadidi
Shah Alam Khan
Hamdy Khamees Thabet
Ozair Alam
Faiyaz Shakeel
Ziyaur Rahman
Muhammad Wahab Amjad

Frontiers in Chemistry

doi 10.3389/fchem.2024.1409042

1,642 views

Editorial

Published on 16 Apr 2024

Editorial: Small molecules and smart drug delivery systems for combination cancer immunotherapy

in Medicinal and Pharmaceutical Chemistry

Claudia Ferroni
Greta Varchi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1412624

1,057 views
1 citation

Original Research

Published on 16 Apr 2024

Discovery of novel melatonin–mydroxyquinoline hybrids as multitarget strategies for Alzheimer’s disease therapy

in Medicinal and Pharmaceutical Chemistry

Wei Wang
Tingting Pan
Rui Su
Mingbin Chen
Wandi Xiong
Congjun Xu
Ling Huang

Frontiers in Chemistry

doi 10.3389/fchem.2024.1374930

1,927 views
5 citations

Original Research

Published on 16 Apr 2024

Integration of the Butina algorithm and ensemble learning strategies for the advancement of a pharmacophore ligand-based model: an in silico investigation of apelin agonists

in Medicinal and Pharmaceutical Chemistry

Xuan-Truc Dinh Tran
Tieu-Long Phan
Van-Thinh To
Ngoc-Vi Nguyen Tran
Nhu-Ngoc Song Nguyen
Dong-Nghi Hoang Nguyen
Ngoc-Tam Nguyen Tran
Tuyen Ngoc Truong

Frontiers in Chemistry

doi 10.3389/fchem.2024.1382319

2,624 views
1 citation

Review

Published on 11 Apr 2024

Biological activity of the essential oil of Drimys winteri

in Medicinal and Pharmaceutical Chemistry

Myriam Navarro
Felipe Urrejola
Misael Espinoza
Simón Silva
Sebastián González
Diego Utreras
Katia Fernandez
Jessica Bravo

Frontiers in Chemistry

doi 10.3389/fchem.2024.1321300

2,882 views
1 citation

Original Research

Published on 08 Apr 2024

Exploring the multifaceted bioactivities of Lavandula pinnata L. essential oil: promising pharmacological activities

in Medicinal and Pharmaceutical Chemistry

Mounir Haddou
Amine Elbouzidi
Mohamed Taibi
Abdellah Baraich
El Hassania Loukili
Reda Bellaouchi
Ennouaamane Saalaoui
Abdeslam Asehraou
Ahmad Mohammad Salamatullah
Mohammed Bourhia

Frontiers in Chemistry

doi 10.3389/fchem.2024.1383731

2,758 views
10 citations

Original Research

Published on 05 Apr 2024

Exploring theophylline-1,2,4-triazole tethered N-phenylacetamide derivatives as antimicrobial agents: unraveling mechanisms via structure-activity relationship, in vitro validation, and in silico insights

in Medicinal and Pharmaceutical Chemistry

Sadaf Saeed
Irum Shahzadi
Ameer Fawad Zahoor
Aamal A. Al-Mutairi
Shagufta Kamal
Shah Faisal
Ali Irfan
Sami A. Al-Hussain
Muhammed Tilahun Muhammed
Magdi E. A. Zaki

Frontiers in Chemistry

doi 10.3389/fchem.2024.1372378

6,705 views
3 citations

Original Research

Published on 02 Apr 2024

Efficacy and classification of Sesamum indicum linn seeds with Rosa damascena mill oil in uncomplicated pelvic inflammatory disease using machine learning

in Medicinal and Pharmaceutical Chemistry

Sumbul
Arshiya Sultana
Md Belal Bin Heyat
Khaleequr Rahman
Faijan Akhtar
Saba Parveen
Mercedes Briones Urbano
Vivian Lipari
Isabel De la Torre Díez
Azmat Ali Khan

Frontiers in Chemistry

doi 10.3389/fchem.2024.1361980

4,857 views
10 citations

Original Research

Published on 27 Mar 2024

HSA-nanobinders crafted from bioresponsive prodrugs for combined cancer chemoimmunotherapy–an in vitro exploration

in Medicinal and Pharmaceutical Chemistry

Matilde Tubertini
Luca Menilli
Celeste Milani
Cecilia Martini
Maria Luisa Navacchia
Marta Nugnes
Manuela Bartolini
Marina Naldi
Daniele Tedesco
Elisa Martella

Frontiers in Chemistry

doi 10.3389/fchem.2024.1378233

2,986 views
1 citation