Frontiers in Chemistry | Medicinal and Pharmaceutical Chemistry

Original Research

Published on 25 Mar 2024

Comparative study of the chemical composition, antioxidant, and antimicrobial activity of the essential oils extracted from Lavandula abrialis and Lavandula stoechas: in vitro and in silico analysis

in Medicinal and Pharmaceutical Chemistry

Mohamed Radi
Zaina Eddardar
Aziz Drioiche
Firdaous Remok
Md. Eram Hosen
Khalid Zibouh
Brahim Ed-Damsyry
Amale Bouatkiout
Sanae Amine
Hanane Touijer

Frontiers in Chemistry

doi 10.3389/fchem.2024.1353385

3,664 views
5 citations

Correction

Published on 22 Mar 2024

Corrigendum: Double cross-linked graphene oxide hydrogel for promoting healing of diabetic ulcers

in Medicinal and Pharmaceutical Chemistry

Wenxu Liu
Yunfang Yang
Meiying Li
Jingxin Mo

Frontiers in Chemistry

doi 10.3389/fchem.2024.1393387

1,481 views

Original Research

Published on 21 Mar 2024

Revisiting methotrexate and phototrexate Zinc15 library-based derivatives using deep learning in-silico drug design approach

in Medicinal and Pharmaceutical Chemistry

Farhan Siddique
Ahmar Anwaar
Maryam Bashir
Sumaira Nadeem
Ravi Rawat
Volkan Eyupoglu
Samina Afzal
Mehvish Bibi
Yousef A. Bin Jardan
Mohammed Bourhia

Frontiers in Chemistry

doi 10.3389/fchem.2024.1380266

4,098 views
8 citations

Original Research

Published on 18 Mar 2024

Synthesis and biological evaluation of novel benzothiazole derivatives as potential anticancer and antiinflammatory agents

in Medicinal and Pharmaceutical Chemistry

Xuemei Xu
Zhaojingtao Zhu
Siyu Chen
Yanneng Fu
Jinxia Zhang
Yangyang Guo
Zhouyang Xu
Yingying Xi
Xuebao Wang
Faqing Ye

Frontiers in Chemistry

doi 10.3389/fchem.2024.1384301

20,316 views
11 citations

Original Research

Published on 13 Mar 2024

Synthesis and biological evaluation of pyridylpiperazine hybrid derivatives as urease inhibitors

in Medicinal and Pharmaceutical Chemistry

Muhammad Akash
Sumera Zaib
Matloob Ahmad
Sadia Sultan
Sami A. Al-Hussain

Frontiers in Chemistry

doi 10.3389/fchem.2024.1371377

5,374 views
4 citations

Original Research

Published on 29 Feb 2024

Exploring pyrrolidinyl-spirooxindole natural products as promising platforms for the synthesis of novel spirooxindoles as EGFR/CDK2 inhibitors for halting breast cancer cells

in Medicinal and Pharmaceutical Chemistry

Mohamed S. Nafie
Abdullah Mohammed Al-Majid
M. Ali
Abdulmajeed Abdullah Alayyaf
Matti Haukka
Sajda Ashraf
Zaheer Ul-Haq
Ayman El-Faham
Assem Barakat

Frontiers in Chemistry

doi 10.3389/fchem.2024.1364378

5,465 views
6 citations

Original Research

Published on 27 Feb 2024

Anti-ulcerative colitis effects of chemically characterized extracts from Calliandra haematocephala in acetic acid-induced ulcerative colitis

in Medicinal and Pharmaceutical Chemistry

Inaam Ur Rehman
Mohammad Saleem
Syed Atif Raza
Saher Bashir
Taha Muhammad
Shahzad Asghar
Muhammad Usman Qamar
Tawaf Ali Shah
Yousef A. Bin Jardan
Amare Bitew Mekonnen

Frontiers in Chemistry

doi 10.3389/fchem.2024.1291230

4,703 views
4 citations

Original Research

Published on 22 Feb 2024

Double cross-linked graphene oxide hydrogel for promoting healing of diabetic ulcers

in Medicinal and Pharmaceutical Chemistry

Wenxu Liu
Yunfang Yang
Meiying Li
Jingxin Mo

Frontiers in Chemistry

doi 10.3389/fchem.2024.1355646

3,059 views
1 citation

Original Research

Published on 16 Feb 2024

Targeting NF-κB signaling cascades of glioblastoma by a natural benzophenone, garcinol, via in vitro and molecular docking approaches

in Medicinal and Pharmaceutical Chemistry

Syed Mohd Danish Rizvi
Ibrahim A. Almazni
Mamdoh S. Moawadh
Zeyad M. Alharbi
Nawal Helmi
Leena S. Alqahtani
Talib Hussain
Ahmed Alafnan
Afrasim Moin
AbdElmoneim O. Elkhalifa

Frontiers in Chemistry

doi 10.3389/fchem.2024.1352009

4,409 views
2 citations

Original Research

Published on 15 Feb 2024

Chemical profiling of volatile compounds of the essential oil of grey-leaved rockrose (Cistus albidus L.) and its antioxidant, anti-inflammatory, antibacterial, antifungal, and anticancer activity in vitro and in silico

in Medicinal and Pharmaceutical Chemistry

Amine Elbouzidi
Mohamed Taibi
Salah Laaraj
El Hassania Loukili
Mounir Haddou
Naoufal El Hachlafi
Hanae Naceiri Mrabti
Abdellah Baraich
Reda Bellaouchi
Abdeslam Asehraou

Frontiers in Chemistry

doi 10.3389/fchem.2024.1334028

10,146 views
28 citations

Correction

Published on 01 Feb 2024

Corrigendum: In vitro and in vivo evaluation of alginate hydrogel-based wound dressing loaded with green chemistry cerium oxide nanoparticles

in Medicinal and Pharmaceutical Chemistry

Ran Zhao
Chenyuyao Zhao
Yi Wan
Muhammad Majid
Syed Qamar Abbas
Yibing Wang

Frontiers in Chemistry

doi 10.3389/fchem.2024.1373205

2,151 views

Perspective

Published on 31 Jan 2024

BacPROTACs targeting Clp protease: a promising strategy for anti-mycobacterial drug discovery

in Medicinal and Pharmaceutical Chemistry

Andressa Francielli Bonjorno
Aline Renata Pavan
Guilherme F. S. Fernandes
Cauê Benito Scarim
Daniele Castagnolo
Jean Leandro Dos Santos

Frontiers in Chemistry

doi 10.3389/fchem.2024.1358539

7,342 views
4 citations

Original Research

Published on 31 Jan 2024

Characterization and comparative evaluation of wound healing potential of Ajugarin I and Ajuga bracteosa Wall. ex Benth

in Medicinal and Pharmaceutical Chemistry

Yusra Wasti
Durdana Muntaqua
Muhammad Majid
Iffat Naz
Aroosa Zafar
Safir Ullah Khan
Syeda Tayyaba Batool Kazmi
Tofeeq Ur Rehman
Nadeem Irshad
Humaira Fatima

Frontiers in Chemistry

doi 10.3389/fchem.2023.1325578

3,259 views
6 citations

Original Research

Published on 25 Jan 2024

Pb-214/Bi-214-TCMC-Trastuzumab inhibited growth of ovarian cancer in preclinical mouse models

in Medicinal and Pharmaceutical Chemistry

Abdullah Metebi
Nathan Kauffman
Lu Xu
Satyendra Kumar Singh
Chelsea Nayback
Jinda Fan
Nathan Johnson
John Diemer
Terry Grimm
Mike Zamiara

Frontiers in Chemistry

doi 10.3389/fchem.2023.1322773

5,210 views
4 citations

Review

Published on 22 Jan 2024

Aconitine and its derivatives: bioactivities, structure-activity relationships and preliminary molecular mechanisms

in Medicinal and Pharmaceutical Chemistry

Pengyu Zhao
Ye Tian
Yuefei Geng
Chenjuan Zeng
Xiuying Ma
Jie Kang
Lin Lu
Xin Zhang
Bo Tang
Funeng Geng

Frontiers in Chemistry

doi 10.3389/fchem.2024.1339364

7,407 views
9 citations

Original Research

Published on 22 Jan 2024

Integrating computational methods guided the discovery of phytochemicals as potential Pin1 inhibitors for cancer: pharmacophore modeling, molecular docking, MM-GBSA calculations and molecular dynamics studies

in Medicinal and Pharmaceutical Chemistry

Abdulrahim A. Alzain
Fatima A. Elbadwi
Tagyedeen H. Shoaib
Asmaa E. Sherif
Wadah Osman
Ahmed Ashour
Gamal A. Mohamed
Sabrin R. M. Ibrahim
Eun Joo Roh
Ahmed H. E. Hassan

Frontiers in Chemistry

doi 10.3389/fchem.2024.1339891

5,622 views
5 citations