Frontiers in Chemistry | Medicinal and Pharmaceutical Chemistry

Original Research

Published on 19 Jan 2024

Origanum majorana L. polyphenols: in vivo antiepileptic effect, in silico evaluation of their bioavailability, and interaction with the NMDA receptor

in Medicinal and Pharmaceutical Chemistry

Amal Amaghnouje
Mohamed Chebaibi
Saeed M. Aldossari
Hazem K. Ghneim
Fatima Ez-zahra Amrati
Imane Es-Safi
Francesca Di Cristo
Anna Calarco
Sanae Achour
Fabrizio Carta

Frontiers in Chemistry

doi 10.3389/fchem.2023.1257769

2,765 views
3 citations

Original Research

Published on 19 Jan 2024

Chemical composition, antioxidant, and antimicrobial properties of Mentha subtomentella: in sight in vitro and in silico analysis

in Medicinal and Pharmaceutical Chemistry

Fatima Brahmi
Nour Eddine Bentouhami
Youssef Rbah
Amine Elbouzidi
Ouafae Mokhtari
Ahmad Mohammad Salamatullah
Samir Ibenmoussa
Mohammed Bourhia
Mohamed Addi
Abdeslam Asehraou

Frontiers in Chemistry

doi 10.3389/fchem.2023.1341704

3,464 views
2 citations

Original Research

Published on 16 Jan 2024

Elucidating the binding mechanism of SARS-CoV-2 NSP6-TBK1 and structure-based designing of phytocompounds inhibitors for instigating the host immune response

in Medicinal and Pharmaceutical Chemistry

Muhammad Suleman
Iqra Ishaq
Haji Khan
Safir Ullah khan
Rehana Masood
Norah A. Albekairi
Abdulrahman Alshammari
Sergio Crovella

Frontiers in Chemistry

doi 10.3389/fchem.2023.1346796

3,669 views
5 citations

Original Research

Published on 16 Jan 2024

ROS-dependent catalytic mechanism of melatonin metabolism and its application in the measurement of reactive oxygen

in Medicinal and Pharmaceutical Chemistry

Xiangge Tian
Xiaohui Kang
Fei Yan
Lei Feng
Xiaokui Huo
Houli Zhang
Yan Wang
Xia Lv
Xiaochi Ma
Jinsong Yuan

Frontiers in Chemistry

doi 10.3389/fchem.2023.1229199

2,107 views
3 citations

Original Research

Published on 11 Jan 2024

Versatile approach towards fully desymmetrized trehalose with a novel set of orthogonal protecting groups

in Medicinal and Pharmaceutical Chemistry

Tomáš Vašíček
Benjamin Arensmeyer
Alessandro Monti
Alla Zamyatina

Frontiers in Chemistry

doi 10.3389/fchem.2023.1332837

2,121 views
1 citation

Editorial

Published on 11 Jan 2024

Editorial: Recent advances in medical radiation technology

in Medicinal and Pharmaceutical Chemistry

Samir Acherar

Frontiers in Chemistry

doi 10.3389/fchem.2024.1360379

1,792 views
1 citation

Review

Published on 10 Jan 2024

Research progress of plant-derived natural products in thyroid carcinoma

in Medicinal and Pharmaceutical Chemistry

Qiujing Du
Weidong Shen

Frontiers in Chemistry

doi 10.3389/fchem.2023.1279384

6,735 views
1 citation

Review

Published on 10 Jan 2024

Recent insights into the functions and mechanisms of antisense RNA: emerging applications in cancer therapy and precision medicine

in Medicinal and Pharmaceutical Chemistry

Shahab Ur Rehman
Numan Ullah
Zhenbin Zhang
Yongkang Zhen
Aziz-Ud Din
Hengmi Cui
Mengzhi Wang

Frontiers in Chemistry

doi 10.3389/fchem.2023.1335330

6,186 views
12 citations

Original Research

Published on 10 Jan 2024

Dual COX-2/5-LOX inhibitors from Zanthoxylum simulans inhibit gastric cancer cells by cross-mediating thyroid, estrogen, and oxytocin signaling pathways

in Medicinal and Pharmaceutical Chemistry

Yong-Qiang Tian
Jing Liu
Peng Cheng
Jian Zou
Hui-Fang Xu
Xin-Hua Shi
Yi-Sheng Zhang
Ling Mei

Frontiers in Chemistry

doi 10.3389/fchem.2023.1287570

2,968 views
4 citations

Original Research

Published on 08 Jan 2024

Decoding the secrets: how conformational and structural regulators inhibit the human 20S proteasome

in Medicinal and Pharmaceutical Chemistry

Pedro M. P. Fernandes
Romina A. Guedes
Bruno L. Victor
Jorge A. R. Salvador
Rita C. Guedes

Frontiers in Chemistry

doi 10.3389/fchem.2023.1322628

2,481 views
1 citation

Original Research

Published on 03 Jan 2024

Antioxidant and anticholinesterase properties of Echinometra mathaei and Ophiocoma erinaceus venoms from the Persian Gulf

in Medicinal and Pharmaceutical Chemistry

Hamideh Dehghani
Marzieh Rashedinia
Gholamhossein Mohebbi
Amir Vazirizadeh
Neda Baghban

Frontiers in Chemistry

doi 10.3389/fchem.2023.1332921

3,507 views
6 citations

Review

Published on 22 Dec 2023

Development of fluorophores for the detection of oligomeric aggregates of amyloidogenic proteins found in neurodegenerative diseases

in Medicinal and Pharmaceutical Chemistry

Kristine L. Teppang
Qilin Zhao
Jerry Yang

Frontiers in Chemistry

doi 10.3389/fchem.2023.1343118

2,624 views
4 citations

Original Research

Published on 18 Dec 2023

Evaluation of the in vitro antioxidant and antitumor activity of hydroalcoholic extract from Jatropha mollissima leaves in Wistar rats

in Medicinal and Pharmaceutical Chemistry

Muhammad Omer Iqbal
Yuchao Gu
Imran Ahmad Khan
Ruihong Wang
Jin Chen

Frontiers in Chemistry

doi 10.3389/fchem.2023.1283618

2,333 views
1 citation

Editorial

Published on 15 Dec 2023

Editorial: Hot topic: anti-inflammatory drug discovery

in Medicinal and Pharmaceutical Chemistry

Joana Silva
Gi-Sang Bae
Ahmed Esmat Abdel Moneim
Mohd Saeed
James David Adams
Mohamed L. Ashour

Frontiers in Chemistry

doi 10.3389/fchem.2023.1339736

1,496 views

Original Research

Published on 11 Dec 2023

Synthesis and biological evaluation of novel bi-gold mitocans in lung cancer cells

in Medicinal and Pharmaceutical Chemistry

Wenwen Ding
Qingbin Cui
Wenhua Lu
Yongliang Du
Yao Luo
Yumin Hu
Peng Huang
Shijun Wen

Frontiers in Chemistry

doi 10.3389/fchem.2023.1292115

1,961 views
3 citations

Original Research

Published on 08 Dec 2023

Palladium-catalyzed synthesis and anti-AD biological activity evaluation of N-aryl-debenzeyldonepezil analogues

in Medicinal and Pharmaceutical Chemistry

Jing-Jing Xu
Jiao Luo
Heng Xi
Jin-Bu Xu
Lin-Xi Wan

Frontiers in Chemistry

doi 10.3389/fchem.2023.1282978

1,880 views
1 citation