Frontiers in Chemistry | Medicinal and Pharmaceutical Chemistry

Original Research

Published on 13 Dec 2024

Lotus seed (Nelumbinis semen) extract: anticancer potential and chemoprofiling by in vitro, in silico and GC-MS studies

in Medicinal and Pharmaceutical Chemistry

Vijaya Jyothi Mallela
Mithun Rudrapal
D. S. N. B. K. Prasanth
Praveen Kumar Pasala
Atul R. Bendale
Soumya Bhattacharya
Sahar M. Aldosari
Johra Khan

Frontiers in Chemistry

doi 10.3389/fchem.2024.1505272

1,981 views
2 citations

Review

Published on 10 Dec 2024

Recent advances in the treatment of non-small cell lung cancer with MET inhibitors

in Medicinal and Pharmaceutical Chemistry

Dongna Zhang
Wenying Zhang
He Liu
Pan Liu
Chunxin Li
Yangyang Liu
Jicheng Han
Guangze Zhu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1501844

1,912 views
1 citation

Original Research

Published on 09 Dec 2024

Chemical composition, antimicrobial, and antioxidant properties of essential oils from Artemisia herba-alba asso. and Artemisia huguetii caball. from Morocco: in vitro and in silico evaluation

in Medicinal and Pharmaceutical Chemistry

Mohamed El Ouardi
Aziz Drioiche
Fadoua El Makhoukhi
Jamal Mabrouki
Mohammed Hakmi
Omkulthom Al kamaly
Bshra A. Alsfouk
Brahim Eddamsyry
Hamid Khamar
Touriya Zair

Frontiers in Chemistry

doi 10.3389/fchem.2024.1456684

5,346 views
1 citation

Original Research

Published on 04 Dec 2024

Composition and antimicrobial activity of hydroalcoholic extracts of Pleurotus eryngii var. ferulae and P. eryngii var. elaeoselini

in Medicinal and Pharmaceutical Chemistry

Flavio Polito
Laura De Martino
Giulia Mirabile
Giuseppe Venturella
Maria Letizia Gargano
Vincenzo De Feo
Hazem S. Elshafie
Ippolito Camele

Frontiers in Chemistry

doi 10.3389/fchem.2024.1498787

1,491 views

Original Research

Published on 03 Dec 2024

The study of halogen effect on the reactivity of the serine-targeting covalent warheads

in Medicinal and Pharmaceutical Chemistry

Conghao Gai
Ya Zhang
Shihao Zhang
Xueyan Hu
Yun-Qing Song
Xiaoyu Zhuang
Xiaoyun Chai
Yan Zou
Guang-Bo Ge
Qingjie Zhao

Frontiers in Chemistry

doi 10.3389/fchem.2024.1504453

1,584 views

Original Research

Published on 02 Dec 2024

Cytotoxic activity of phenolic compounds in Bairui Granules obtained from the Chinese medicinal plant Thesium chinense

in Medicinal and Pharmaceutical Chemistry

Shaobin Zhang
Hong Chen
Juan Hua
Shihong Luo

Frontiers in Chemistry

doi 10.3389/fchem.2024.1506792

1,186 views

Original Research

Published on 27 Nov 2024

Antioxidant potential, antimicrobial activity, polyphenol profile analysis, and cytotoxicity against breast cancer cell lines of hydro-ethanolic extracts of leaves of (Ficus carica L.) from Eastern Morocco

in Medicinal and Pharmaceutical Chemistry

Aziz Tikent
Salah Laaraj
Toufik Bouddine
Mohamed Chebaibi
Mohamed Bouhrim
Kaoutar Elfazazi
Ali S. Alqahtani
Omar M. Noman
Lhoussain Hajji
Larbi Rhazi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1505473

2,768 views
4 citations

Editorial

Published on 22 Nov 2024

Editorial: Antibacterial effects and mode of action of new active substances against drug resistant pathogenic bacteria

in Medicinal and Pharmaceutical Chemistry

Abderrahmen Merghni

Frontiers in Chemistry

doi 10.3389/fchem.2024.1526451

618 views

Original Research

Published on 15 Nov 2024

UPLC-ESI/MSn metabolic profiling of Cedrela odorata L. and Toona ciliata M. Roem and in vitro investigation of their anti-diabetic activity supported with molecular docking studies

in Medicinal and Pharmaceutical Chemistry

Heba A. S. El-Nashar
Ayman M. Al-Qaaneh
Md. Shimul Bhuia
Raihan Chowdhury
Mostafa A. Abdel-Maksoud
Hossam Ebaid
Abdul Malik
Muhammad Torequl Islam
Mohammed Aufy
Esraa A. Elhawary

Frontiers in Chemistry

doi 10.3389/fchem.2024.1462309

1,741 views
2 citations

Original Research

Published on 15 Nov 2024

Development of photoactive biomaterial using modified fullerene nanoparticles

in Medicinal and Pharmaceutical Chemistry

Gabrielė Saulėnienė
Monika Kirsnyte-Snioke
Arūnas Stirkė
Vitalija Jasulaitiene
Antanas Straksys
Samuelis Dobilaitis
Wanessa C. M. A. Melo

Frontiers in Chemistry

doi 10.3389/fchem.2024.1432624

3,529 views
1 citation

Original Research

Published on 12 Nov 2024

Synthesis, enzyme inhibition, and docking studies of new schiff bases of disalicylic acid methylene-based derivatives as dual-target antibacterial agents

in Medicinal and Pharmaceutical Chemistry

Lamya H. Al-Wahaibi
Mohamed A. Mahmoud
Hayat Ali Alzahrani
Hesham A. Abou-Zied
Alshaimaa Abdelmoez
Bahaa G. M. Youssif
Stefan Bräse
Safwat M. Rabea

Frontiers in Chemistry

doi 10.3389/fchem.2024.1493906

1,526 views
1 citation

Original Research

Published on 06 Nov 2024

New series of 4,6-diaryl pyrimidines: facile synthesis and antiproliferative activity as dual EGFR/VEGFR-2 inhibitors

in Medicinal and Pharmaceutical Chemistry

Yaser A. Mostafa
Jalil Abdeljalil Assoud
Ahmed Y. Desoky
Samy Mohamady
Nesma M. Mohamed
Ola I. A. Salem
Zainab M. Almarhoon
Stefan Bräse
Bahaa G. M. Youssif

Frontiers in Chemistry

doi 10.3389/fchem.2024.1498104

2,762 views
2 citations

Editorial

Published on 06 Nov 2024

Editorial: Hot topic: anti-inflammatory drug discovery

in Medicinal and Pharmaceutical Chemistry

Abdul Ajees Abdul Salam
Tejas M. Dhameliya
Ahmed Mahal
Sajad Moradi
Paolo Coghi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1512607

1,532 views

Original Research

Published on 31 Oct 2024

Aspidosperma nitidum reduces parasite load and modulates cytokines in BALB/c mice infected with Leishmania (Leishmania) amazonensis

in Medicinal and Pharmaceutical Chemistry

Heliton Patrick Cordovil Brígido
Everton Luiz Pompeu Varela
Antônio Rafael Quadros Gomes
Jorddy Neves Cruz
Juliana Correa-Barbosa
José Edson de Sousa Siqueira
Cristian Kallahan Silva Chagas
Andrey Moacir do Rosário Marinho
Liliane Almeida Carneiro
Márlia Regina Coelho-Ferreira

Frontiers in Chemistry

doi 10.3389/fchem.2024.1492770

1,116 views
4 citations

Original Research

Published on 30 Oct 2024

Exploring the mechanism of tetramethylpyrazine in the treatment of osteoarthritis based on network pharmacology

in Medicinal and Pharmaceutical Chemistry

Juncen Li
Daiying Song
Bohui Li
Yajie Wang
Huilin Sun
Qinglin Li
Xiangming Lin
Di Wang
Guangdong Zhou
Yu Liu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1415390

2,642 views
2 citations

Original Research

Published on 24 Oct 2024

Antioxidant, Anti-Alzheimer’s, anticancer, and cytotoxic properties of peanut oil: in vitro, in silico, and GC-MS analysis

in Medicinal and Pharmaceutical Chemistry

Hanène Djeghim
Djamila Benouchenne
El Hassen Mokrani
Huda Alsaeedi
David Cornu
Mikhael Bechelany
Ahmed Barhoum

Frontiers in Chemistry

doi 10.3389/fchem.2024.1487084

6,393 views
4 citations