Frontiers in Chemistry | Medicinal and Pharmaceutical Chemistry

Correction

Published on 24 Dec 2024

Corrigendum: Radiochemical and biological assessments of a PSMA-I&S cold kit for fast and inexpensive 99mTc-labeling for SPECT imaging and radioguided surgery in prostate cancer

in Medicinal and Pharmaceutical Chemistry

Leonardo Lima Fuscaldi
Danielle Vieira Sobral
Ana Claudia Durante
Fernanda Ferreira Mendonça
Ana Cláudia Camargo Miranda
Carla Salgueiro
Silvia Gomez de Castiglia
Lilian Yuri Itaya Yamaga
Marcelo Livorsi da Cunha
Luciana Malavolta

Frontiers in Chemistry

doi 10.3389/fchem.2024.1539768

1,175 views

Original Research

Published on 23 Dec 2024

Evaluation of the anti-spasmodic activity of essential oils of Ammodaucus leucotrichus fruits and its main chemical component “perillaldehyde” on intestinal smooth muscle contractions of rodents: ex vivo and in silico approaches

in Medicinal and Pharmaceutical Chemistry

Ahmed Karim
Mohamed Marghich
Ouafa Amrani
Abdelhay Addous
Sanae Malek
Leila Beyi
Tarik Harit
Dara Aldisi
Mourad A. M. Aboul-Soud
John P. Giesy

Frontiers in Chemistry

doi 10.3389/fchem.2024.1465674

2,381 views
1 citation

Original Research

Published on 13 Dec 2024

Lotus seed (Nelumbinis semen) extract: anticancer potential and chemoprofiling by in vitro, in silico and GC-MS studies

in Medicinal and Pharmaceutical Chemistry

Vijaya Jyothi Mallela
Mithun Rudrapal
D. S. N. B. K. Prasanth
Praveen Kumar Pasala
Atul R. Bendale
Soumya Bhattacharya
Sahar M. Aldosari
Johra Khan

Frontiers in Chemistry

doi 10.3389/fchem.2024.1505272

3,574 views
4 citations

Review

Published on 10 Dec 2024

Recent advances in the treatment of non-small cell lung cancer with MET inhibitors

in Medicinal and Pharmaceutical Chemistry

Dongna Zhang
Wenying Zhang
He Liu
Pan Liu
Chunxin Li
Yangyang Liu
Jicheng Han
Guangze Zhu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1501844

3,638 views
2 citations

Original Research

Published on 09 Dec 2024

Chemical composition, antimicrobial, and antioxidant properties of essential oils from Artemisia herba-alba asso. and Artemisia huguetii caball. from Morocco: in vitro and in silico evaluation

in Medicinal and Pharmaceutical Chemistry

Mohamed El Ouardi
Aziz Drioiche
Fadoua El Makhoukhi
Jamal Mabrouki
Mohammed Hakmi
Omkulthom Al kamaly
Bshra A. Alsfouk
Brahim Eddamsyry
Hamid Khamar
Touriya Zair

Frontiers in Chemistry

doi 10.3389/fchem.2024.1456684

7,878 views
5 citations

Original Research

Published on 04 Dec 2024

Composition and antimicrobial activity of hydroalcoholic extracts of Pleurotus eryngii var. ferulae and P. eryngii var. elaeoselini

in Medicinal and Pharmaceutical Chemistry

Flavio Polito
Laura De Martino
Giulia Mirabile
Giuseppe Venturella
Maria Letizia Gargano
Vincenzo De Feo
Hazem S. Elshafie
Ippolito Camele

Frontiers in Chemistry

doi 10.3389/fchem.2024.1498787

2,737 views
1 citation

Original Research

Published on 03 Dec 2024

The study of halogen effect on the reactivity of the serine-targeting covalent warheads

in Medicinal and Pharmaceutical Chemistry

Conghao Gai
Ya Zhang
Shihao Zhang
Xueyan Hu
Yun-Qing Song
Xiaoyu Zhuang
Xiaoyun Chai
Yan Zou
Guang-Bo Ge
Qingjie Zhao

Frontiers in Chemistry

doi 10.3389/fchem.2024.1504453

2,695 views
3 citations

Original Research

Published on 02 Dec 2024

Cytotoxic activity of phenolic compounds in Bairui Granules obtained from the Chinese medicinal plant Thesium chinense

in Medicinal and Pharmaceutical Chemistry

Shaobin Zhang
Hong Chen
Juan Hua
Shihong Luo

Frontiers in Chemistry

doi 10.3389/fchem.2024.1506792

2,003 views
5 citations

Original Research

Published on 27 Nov 2024

Antioxidant potential, antimicrobial activity, polyphenol profile analysis, and cytotoxicity against breast cancer cell lines of hydro-ethanolic extracts of leaves of (Ficus carica L.) from Eastern Morocco

in Medicinal and Pharmaceutical Chemistry

Aziz Tikent
Salah Laaraj
Toufik Bouddine
Mohamed Chebaibi
Mohamed Bouhrim
Kaoutar Elfazazi
Ali S. Alqahtani
Omar M. Noman
Lhoussain Hajji
Larbi Rhazi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1505473

5,038 views
11 citations

Editorial

Published on 22 Nov 2024

Editorial: Antibacterial effects and mode of action of new active substances against drug resistant pathogenic bacteria

in Medicinal and Pharmaceutical Chemistry

Abderrahmen Merghni

Frontiers in Chemistry

doi 10.3389/fchem.2024.1526451

1,023 views

Original Research

Published on 15 Nov 2024

Development of photoactive biomaterial using modified fullerene nanoparticles

in Medicinal and Pharmaceutical Chemistry

Gabrielė Saulėnienė
Monika Kirsnyte-Snioke
Arūnas Stirkė
Vitalija Jasulaitiene
Antanas Straksys
Samuelis Dobilaitis
Wanessa C. M. A. Melo

Frontiers in Chemistry

doi 10.3389/fchem.2024.1432624

4,320 views
3 citations

Original Research

Published on 15 Nov 2024

UPLC-ESI/MSn metabolic profiling of Cedrela odorata L. and Toona ciliata M. Roem and in vitro investigation of their anti-diabetic activity supported with molecular docking studies

in Medicinal and Pharmaceutical Chemistry

Heba A. S. El-Nashar
Ayman M. Al-Qaaneh
Md. Shimul Bhuia
Raihan Chowdhury
Mostafa A. Abdel-Maksoud
Hossam Ebaid
Abdul Malik
Muhammad Torequl Islam
Mohammed Aufy
Esraa A. Elhawary

Frontiers in Chemistry

doi 10.3389/fchem.2024.1462309

2,727 views
2 citations

Original Research

Published on 12 Nov 2024

Synthesis, enzyme inhibition, and docking studies of new schiff bases of disalicylic acid methylene-based derivatives as dual-target antibacterial agents

in Medicinal and Pharmaceutical Chemistry

Lamya H. Al-Wahaibi
Mohamed A. Mahmoud
Hayat Ali Alzahrani
Hesham A. Abou-Zied
Alshaimaa Abdelmoez
Bahaa G. M. Youssif
Stefan Bräse
Safwat M. Rabea

Frontiers in Chemistry

doi 10.3389/fchem.2024.1493906

2,821 views
4 citations

Original Research

Published on 06 Nov 2024

New series of 4,6-diaryl pyrimidines: facile synthesis and antiproliferative activity as dual EGFR/VEGFR-2 inhibitors

in Medicinal and Pharmaceutical Chemistry

Yaser A. Mostafa
Jalil Abdeljalil Assoud
Ahmed Y. Desoky
Samy Mohamady
Nesma M. Mohamed
Ola I. A. Salem
Zainab M. Almarhoon
Stefan Bräse
Bahaa G. M. Youssif

Frontiers in Chemistry

doi 10.3389/fchem.2024.1498104

4,325 views
7 citations

Editorial

Published on 06 Nov 2024

Editorial: Hot topic: anti-inflammatory drug discovery

in Medicinal and Pharmaceutical Chemistry

Abdul Ajees Abdul Salam
Tejas M. Dhameliya
Ahmed Mahal
Sajad Moradi
Paolo Coghi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1512607

2,431 views

Original Research

Published on 31 Oct 2024

Aspidosperma nitidum reduces parasite load and modulates cytokines in BALB/c mice infected with Leishmania (Leishmania) amazonensis

in Medicinal and Pharmaceutical Chemistry

Heliton Patrick Cordovil Brígido
Everton Luiz Pompeu Varela
Antônio Rafael Quadros Gomes
Jorddy Neves Cruz
Juliana Correa-Barbosa
José Edson de Sousa Siqueira
Cristian Kallahan Silva Chagas
Andrey Moacir do Rosário Marinho
Liliane Almeida Carneiro
Márlia Regina Coelho-Ferreira

Frontiers in Chemistry

doi 10.3389/fchem.2024.1492770

1,861 views
4 citations

Original Research

Published on 30 Oct 2024

Exploring the mechanism of tetramethylpyrazine in the treatment of osteoarthritis based on network pharmacology

in Medicinal and Pharmaceutical Chemistry

Juncen Li
Daiying Song
Bohui Li
Yajie Wang
Huilin Sun
Qinglin Li
Xiangming Lin
Di Wang
Guangdong Zhou
Yu Liu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1415390

4,506 views
3 citations

Original Research

Published on 24 Oct 2024

Antioxidant, Anti-Alzheimer’s, anticancer, and cytotoxic properties of peanut oil: in vitro, in silico, and GC-MS analysis

in Medicinal and Pharmaceutical Chemistry

Hanène Djeghim
Djamila Benouchenne
El Hassen Mokrani
Huda Alsaeedi
David Cornu
Mikhael Bechelany
Ahmed Barhoum

Frontiers in Chemistry

doi 10.3389/fchem.2024.1487084

7,760 views
11 citations

Original Research

Published on 23 Oct 2024

Synthesis of new triazole derivatives and their potential applications for removal of heavy metals from aqueous solution and antibacterial activities

in Medicinal and Pharmaceutical Chemistry

Chunyun Xu
Na Yang
Haichun Yu
Xiaojing Wang

Frontiers in Chemistry

doi 10.3389/fchem.2024.1473097

4,023 views
1 citation

Original Research

Published on 21 Oct 2024

Development of novel CDK9 and CYP3A4 inhibitors for cancer therapy through field and computational approaches

in Medicinal and Pharmaceutical Chemistry

Aisha A. Alsfouk
Abdelmoujoud Faris
Ivana Cacciatore
Radwan Alnajjar

Frontiers in Chemistry

doi 10.3389/fchem.2024.1473398

2,726 views
4 citations

Original Research

Published on 16 Oct 2024

Synthesis and antibacterial potential of novel thymol derivatives against methicillin-resistant Staphylococcus aureus and P. aeruginosa pathogenic bacteria

in Medicinal and Pharmaceutical Chemistry

Ashutosh Shahi
Rakshit Manhas
Srija Bhattacharya
Arti Rathore
Puneet Kumar
Jayanta Samanta
Manish Kumar Sharma
Avisek Mahapa
Prasoon Gupta
Jasha Momo H. Anal

Frontiers in Chemistry

doi 10.3389/fchem.2024.1482852

4,201 views
9 citations

Original Research

Published on 15 Oct 2024

Sustainable synthesis of silver nanoparticles from Azadirachta indica: antimicrobial, antioxidant and in silico analysis for periodontal treatment

in Medicinal and Pharmaceutical Chemistry

Binapani Barik
Bhabani Sankar Satapathy
Gurudutta Pattnaik
Desai Vijay Bhavrao
Krishna Prasad Shetty

Frontiers in Chemistry

doi 10.3389/fchem.2024.1489253

3,969 views
11 citations

Original Research

Published on 08 Oct 2024

Computational exploration of acefylline derivatives as MAO-B inhibitors for Parkinson’s disease: insights from molecular docking, DFT, ADMET, and molecular dynamics approaches

in Medicinal and Pharmaceutical Chemistry

Ali Irfan
Ameer Fawad Zahoor
Yassir Boulaamane
Sadia Javed
Huma Hameed
Amal Maurady
Muhammed Tilahun Muhammed
Sajjad Ahmad
Aamal A. Al-Mutairi
Irum Shahzadi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1449165

5,209 views
1 citation

Original Research

Published on 08 Oct 2024

Stretching the structural envelope of imatinib to reduce β-amyloid production by modulating both β- and γ-secretase cleavages of APP

in Medicinal and Pharmaceutical Chemistry

William J. Netzer
Anjana Sinha
Mondana Ghias
Emily Chang
Katherina Gindinova
Emily Mui
Ji-Seon Seo
Subhash C. Sinha

Frontiers in Chemistry

doi 10.3389/fchem.2024.1381205

1,817 views
1 citation