Frontiers in Chemistry | Medicinal and Pharmaceutical Chemistry

Original Research

Published on 23 Oct 2024

Synthesis of new triazole derivatives and their potential applications for removal of heavy metals from aqueous solution and antibacterial activities

in Medicinal and Pharmaceutical Chemistry

Chunyun Xu
Na Yang
Haichun Yu
Xiaojing Wang

Frontiers in Chemistry

doi 10.3389/fchem.2024.1473097

2,917 views
1 citation

Original Research

Published on 21 Oct 2024

Development of novel CDK9 and CYP3A4 inhibitors for cancer therapy through field and computational approaches

in Medicinal and Pharmaceutical Chemistry

Aisha A. Alsfouk
Abdelmoujoud Faris
Ivana Cacciatore
Radwan Alnajjar

Frontiers in Chemistry

doi 10.3389/fchem.2024.1473398

1,877 views
1 citation

Original Research

Published on 16 Oct 2024

Synthesis and antibacterial potential of novel thymol derivatives against methicillin-resistant Staphylococcus aureus and P. aeruginosa pathogenic bacteria

in Medicinal and Pharmaceutical Chemistry

Ashutosh Shahi
Rakshit Manhas
Srija Bhattacharya
Arti Rathore
Puneet Kumar
Jayanta Samanta
Manish Kumar Sharma
Avisek Mahapa
Prasoon Gupta
Jasha Momo H. Anal

Frontiers in Chemistry

doi 10.3389/fchem.2024.1482852

2,591 views
3 citations

Original Research

Published on 15 Oct 2024

Sustainable synthesis of silver nanoparticles from Azadirachta indica: antimicrobial, antioxidant and in silico analysis for periodontal treatment

in Medicinal and Pharmaceutical Chemistry

Binapani Barik
Bhabani Sankar Satapathy
Gurudutta Pattnaik
Desai Vijay Bhavrao
Krishna Prasad Shetty

Frontiers in Chemistry

doi 10.3389/fchem.2024.1489253

2,127 views
2 citations

Original Research

Published on 08 Oct 2024

Computational exploration of acefylline derivatives as MAO-B inhibitors for Parkinson’s disease: insights from molecular docking, DFT, ADMET, and molecular dynamics approaches

in Medicinal and Pharmaceutical Chemistry

Ali Irfan
Ameer Fawad Zahoor
Yassir Boulaamane
Sadia Javed
Huma Hameed
Amal Maurady
Muhammed Tilahun Muhammed
Sajjad Ahmad
Aamal A. Al-Mutairi
Irum Shahzadi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1449165

3,337 views
1 citation

Original Research

Published on 08 Oct 2024

Stretching the structural envelope of imatinib to reduce β-amyloid production by modulating both β- and γ-secretase cleavages of APP

in Medicinal and Pharmaceutical Chemistry

William J. Netzer
Anjana Sinha
Mondana Ghias
Emily Chang
Katherina Gindinova
Emily Mui
Ji-Seon Seo
Subhash C. Sinha

Frontiers in Chemistry

doi 10.3389/fchem.2024.1381205

1,171 views

Original Research

Published on 03 Oct 2024

Stemona alkaloid derivative induce ferroptosis of colorectal cancer cell by mediating carnitine palmitoyltransferase 1

in Medicinal and Pharmaceutical Chemistry

He Yang
Ling Wang
Mengcheng Zhang
Xingkang Wu
Zhenyu Li
Kaiqing Ma

Frontiers in Chemistry

doi 10.3389/fchem.2024.1478674

1,676 views
1 citation

Review

Published on 26 Sep 2024

Venom-derived peptides for breaking through the glass ceiling of drug development

in Medicinal and Pharmaceutical Chemistry

Lou Freuville
Chloé Matthys
Loïc Quinton
Jean-Pierre Gillet

Frontiers in Chemistry

doi 10.3389/fchem.2024.1465459

5,683 views
1 citation

Original Research

Published on 24 Sep 2024

Topological indices based VIKOR assisted multi-criteria decision technique for lung disorders

in Medicinal and Pharmaceutical Chemistry

Tahreem Ashraf
Nazeran Idrees

Frontiers in Chemistry

doi 10.3389/fchem.2024.1407911

1,480 views
3 citations

Original Research

Published on 20 Sep 2024

Structure-based virtual screening towards the discovery of novel thrombin inhibitors with Anti-HCC activities

in Medicinal and Pharmaceutical Chemistry

Xiaoxi Zhang
Xumei Zheng
Chun Han
Lintao Wu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1451574

1,241 views
2 citations

Editorial

Published on 19 Sep 2024

Editorial: Advances in wound repair and regeneration: novel materials, targets and applications

in Medicinal and Pharmaceutical Chemistry

Xinwei Cheng
Jia Zhou

Frontiers in Chemistry

doi 10.3389/fchem.2024.1487091

886 views

Editorial

Published on 17 Sep 2024

Editorial: Novel compounds from chemistry to druggable candidates

in Medicinal and Pharmaceutical Chemistry

Pete Rose
Jawad Nasim
Yi-Zhun Zhu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1494407

1,127 views

Original Research

Published on 13 Sep 2024

Phytochemical analysis, identification of bioactive compounds using GC-MS, in vitro and in silico hypoglycemic potential, in vitro antioxidant potential, and in silico ADME analysis of Chlorophytum comosum root and leaf

in Medicinal and Pharmaceutical Chemistry

P. Kavya
R. C. Theijeswini
M. Gayathri

Frontiers in Chemistry

doi 10.3389/fchem.2024.1458505

3,222 views
4 citations

Original Research

Published on 13 Sep 2024

Phytochemical profile, physicochemical, antioxidant and antimicrobial properties of Juniperus phoenicea and Tetraclinis articulate: in vitro and in silico approaches

in Medicinal and Pharmaceutical Chemistry

Ayoub Asbabou
Touijer Hanane
Aman Allah Gourich
Farhan Siddique
Aziz Drioiche
Firdaous Remok
Soukaina Saidi
Imad Adadi
Hamid Khamar
Khalid S. Almaary

Frontiers in Chemistry

doi 10.3389/fchem.2024.1397961

3,089 views
2 citations

Original Research

Published on 10 Sep 2024

Salsoline derivatives, genistein, semisynthetic derivative of kojic acid, and naringenin as inhibitors of A42R profilin-like protein of monkeypox virus: in silico studies

in Medicinal and Pharmaceutical Chemistry

Mohamed Chebaibi
Mohammed Bourhia
Fatima ez-zahra Amrati
Meryem Slighoua
Ibrahim Mssillou
Mourad A. M. Aboul-Soud
Asaad Khalid
Rym Hassani
Dalila Bousta
Sanae Achour

Frontiers in Chemistry

doi 10.3389/fchem.2024.1445606

2,587 views
5 citations

Original Research

Published on 06 Sep 2024

Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity

in Medicinal and Pharmaceutical Chemistry

Lamya H. Al-Wahaibi
Hesham A. Abou-Zied
Mostafa H. Abdelrahman
Martha M. Morcoss
Laurent Trembleau
Bahaa G. M. Youssif
Stefan Bräse

Frontiers in Chemistry

doi 10.3389/fchem.2024.1432920

2,479 views
4 citations