Frontiers in Chemistry | Medicinal and Pharmaceutical Chemistry

Original Research

Published on 16 Jul 2024

Extracellular vesicles enhance the in vivo antitumor effects of millettia species-derived compounds in chronic myelogenous leukemia therapy

in Medicinal and Pharmaceutical Chemistry

Zongzhou Xie
Xiaozhen Cheng
JianCang Mao
Yingqi Zhu
Le Li
Zhenxin Mei

Frontiers in Chemistry

doi 10.3389/fchem.2024.1425318

1,390 views
1 citation

Original Research

Published on 16 Jul 2024

Synthesis, characterization, and anti-cancer potential of novel p53-mediated Mdm2 and Pirh2 modulators: an integrated In silico and In vitro approach

in Medicinal and Pharmaceutical Chemistry

Sarfaraj Niazi
C. P. Kavana
H. K. Aishwarya
Chandan Dharmashekar
Anisha Jain
Tanveer A. Wani
Chandan Shivamallu
Madhusudan N. Purohit
Shiva Prasad Kollur

Frontiers in Chemistry

doi 10.3389/fchem.2024.1366370

1,932 views

Original Research

Published on 15 Jul 2024

Development of a versatile [68Ga]Ga-FAPI-46 automated synthesis suitable to multi-elutions of germanium-68/gallium-68 generators

in Medicinal and Pharmaceutical Chemistry

Louis-Paul Paty
Simon Degueldre
Claire Provost
Camille Schmitt
Laura Trump
Julien Fouque
Charles Vriamont
Frank Valla
Thibault Gendron
Olivier Madar

Frontiers in Chemistry

doi 10.3389/fchem.2024.1411312

2,830 views
1 citation

Original Research

Published on 12 Jul 2024

Comprehensive analysis of bioactive compounds in Crocus sativus stamens extracts by HPLC-DAD: investigating antidiabetic activity via in vitro, in vivo, and molecular docking simulation

in Medicinal and Pharmaceutical Chemistry

Samira Mamri
Nour Elhouda Daoudi
Abedellah Baraich
Sabir Ouahhoud
Amine Khoulati
Mohammed Choukri
Abdeslam Asehraou
Mohamed Bnouham
Bassem Jaouadi
Abdelkrim Abousalham

Frontiers in Chemistry

doi 10.3389/fchem.2024.1419120

2,887 views
2 citations

Original Research

Published on 09 Jul 2024

Pharmacophore-based virtual screening of commercial databases against β-secretase 1 for drug development against Alzheimer’s disease

in Medicinal and Pharmaceutical Chemistry

Xu Han
Kaibo Guo

Frontiers in Chemistry

doi 10.3389/fchem.2024.1412349

2,758 views

Review

Published on 05 Jul 2024

Insights into the stereoisomerism of dihydroquercetin: analytical and pharmacological aspects

in Medicinal and Pharmaceutical Chemistry

Roman P. Terekhov
Anastasiya D. Savina
Denis I. Pankov
Maria D. Korochkina
Amir Taldaev
Liubov M. Yakubovich
Sergey P. Zavadskiy
Anastasiya K. Zhevlakova
Irina A. Selivanova

Frontiers in Chemistry

doi 10.3389/fchem.2024.1439167

3,035 views
4 citations

Original Research

Published on 04 Jul 2024

The chemical composition and the preservative, antimicrobial, and antioxidant effects of Thymus broussonetii Boiss. essential oil: an in vitro and in silico approach

in Medicinal and Pharmaceutical Chemistry

Smahane Boukhira
Fatima Ez-Zahra Amrati
Mohamed Chebaibi
Andriy Grafov
Ramzi A. Mothana
Hanan M. Al-Yousef
Dalila Bousta

Frontiers in Chemistry

doi 10.3389/fchem.2024.1402310

4,017 views
2 citations

Original Research

Published on 03 Jul 2024

Discovery and prospects of new heterocyclic Isatin-hydrazide derivative with a novel role as estrogen receptor α degrader in breast cancer cells

in Medicinal and Pharmaceutical Chemistry

Muhammad Nouman Arif
Sadia Sarwar
Farhat Firdous
Rahman Shah Zaib Saleem
Humaira Nadeem
Abir Abdullah Alamro
Amani Ahmad Alghamdi
Atekah Hazza Alshammari
Omer Farooq
Rashid Ali Khan

Frontiers in Chemistry

doi 10.3389/fchem.2024.1424637

5,819 views
3 citations

Review

Published on 02 Jul 2024

Research progress of Gastrodia elata Blume polysaccharides: a review of chemical structures and biological activities

in Medicinal and Pharmaceutical Chemistry

Liu Yang
Shi-Hui Qin
Cheng-Ting Zi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1395222

3,279 views
6 citations

Original Research

Published on 26 Jun 2024

Design, synthesis, and evaluation of 1,4-benzothiazine-3-one containing bisamide derivatives as dual inhibitors of Staphylococcus aureus with plausible application in a urinary catheter

in Medicinal and Pharmaceutical Chemistry

Kaushal Naithani
Arka Das
Mamta Ushare
Subham Nath
Rashmita Biswas
Anirban Kundu
Kazi Tawsif Ahmed
Utpal Mohan
Subhendu Bhowmik

Frontiers in Chemistry

doi 10.3389/fchem.2024.1420593

3,727 views

Editorial

Published on 25 Jun 2024

Editorial: Five-membered heterocycles: synthesis and applications

in Medicinal and Pharmaceutical Chemistry

Mohammad Abrar Alam

Frontiers in Chemistry

doi 10.3389/fchem.2024.1445671

3,195 views
1 citation

Editorial

Published on 24 Jun 2024

Editorial: Computational drug discovery of medicinal compounds for cancer management, volume II

in Medicinal and Pharmaceutical Chemistry

Khurshid Ahmad
Sibhghatulla Shaikh
Faez Iqbal Khan
Mohammad Ehtisham Khan

Frontiers in Chemistry

doi 10.3389/fchem.2024.1446510

1,189 views
1 citation

Correction

Published on 18 Jun 2024

Corrigendum: HSA-nanobinders crafted from bioresponsive prodrugs for combined cancer chemoimmunotherapy–an in vitro exploration

in Medicinal and Pharmaceutical Chemistry

Matilde Tubertini
Luca Menilli
Celeste Milani
Cecilia Martini
Maria Luisa Navacchia
Marta Nugnes
Manuela Bartolini
Marina Naldi
Daniele Tedesco
Elisa Martella

Frontiers in Chemistry

doi 10.3389/fchem.2024.1443822

844 views

Original Research

Published on 18 Jun 2024

In silico discovery of potential PPI inhibitors for anti-lung cancer activity by targeting the CCND1-CDK4 complex via the P21 inhibition mechanism

in Medicinal and Pharmaceutical Chemistry

Weijian Tang
Tao Shen
Zhoumiao Chen

Frontiers in Chemistry

doi 10.3389/fchem.2024.1404573

1,987 views
2 citations

Original Research

Published on 11 Jun 2024

In vivo and in silico studies of the effects of oil extracted from Cannabis sativa L. seeds on healing of burned skin wounds in rats

in Medicinal and Pharmaceutical Chemistry

Mouna Bouarfa
Mohamed Chebaibi
Fatima Ez-Zahra Amrati
Zouhair Souirti
Hamza Saghrouchni
Yassine El atki
Khalid Bekkouche
Hajar Mourabiti
Amina Bari
John P. Giesy

Frontiers in Chemistry

doi 10.3389/fchem.2024.1381527

2,460 views
2 citations

Original Research

Published on 10 Jun 2024

Natural product nanozymes of herbal extract galangin in managing hepatocellular carcinoma

in Medicinal and Pharmaceutical Chemistry

Erhao Wang
Yuxia Wu
Yan Wang
Jiao Li
Xiuzhen Liang
Zhongtao Wang
Xiaofei Liu
Faming Feng
JianCang Mao
Yingqi Zhu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1426634

1,568 views
2 citations