Frontiers in Clinical Diabetes and Healthcare

Original Research

Published on 16 Dec 2025

Real-world effectiveness and safety of imeglimin: a single-center retrospective cohort study in Japan

in Diabetes Therapies

Taro Fujisawa
Takehiro Kato
Kazuhisa Takami
Shinya Fukuda
Risako Imai
Tomoya Kawashima
Ryosuke Horita
Katsuhisa Sakai
Akiko Yamada
Shin Tsunekawa

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1694522

552 views

Editorial

Published on 08 Dec 2025

Editorial: Non-insulin pharmacotherapies for the treatment of type 2 diabetes and obesity - old and new players

in Diabetes Therapies

Dimitrios Patoulias
Emir Muzurović
Manfredi Rizzo

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1747914

343 views

Case Report

Published on 15 Oct 2025

Case Report: When genetic diagnosis comes late: lessons from a DEND syndrome patient successfully transitioned to sulfonylurea

in Diabetes Therapies

Gabriella de Medeiros Abreu
Ritiele Bastos de Souza
Marília Chaves Bernardo
Jardeson Lima da Cruz Junior
Amanda Ferreira
Deborah Snaider
Ana Carolina Proença da Fonseca
Kaio Cezar Rodrigues Salum
Verônica Marques Zembrzuski
Marco Antonio Lima

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1654037

1,154 views

Original Research

Published on 17 Sep 2025

Association between eating behavior patterns and the therapeutic efficacy of GLP-1 receptor agonists in individuals with type 2 diabetes: a multicenter prospective observational study

in Diabetes Therapies

Yuya Koide
Takehiro Kato
Makoto Hayashi
Hisashi Daido
Takako Maruyama
Takuma Ishihara
Kayoko Nishimura
Shin Tsunekawa
Daisuke Yabe

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1638681

8,034 views
2 citations

Systematic Review

Published on 02 Sep 2025

Therapeutic effects of Balanites aegyptiaca DEL extract on diabetes mellitus: a systematic review

in Diabetes Therapies

Olubukola Adebisi Odeniran
Adegboyega Moses Oyefabi
Ifeoluwa Temitayo Oyeyemi
Adewale Adegboyega Oke
Grace Aziken
Grace Adebayo-Gege
Peter Ifeoluwa Adegbola
Lawrence Dayo Adedayo
Olunike Rebecca Abodunrin
Folahanmi Tomiwa Akinsolu

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1651789

2,062 views

Systematic Review

Published on 27 Aug 2025

GLP-1 receptor agonists and pancreatic beta cell apoptosis in diabetes mellitus: a systematic review and meta-analysis of preclinical studies

in Diabetes Therapies

Nicolas Rea
Prakash V. A. K. Ramdass

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1579961

3,080 views

Review

Published on 10 Jul 2025

Exploring the multifaceted roles of GLP-1 receptor agonists; a comprehensive review

in Diabetes Therapies

Bisma Fatima Hammad
Nimrah Zafar
Muneeb Ullah
Syeda Jazilah Faisal
Fizzah Iftikhar
Haadia Waheed
Muhammad Waleed Muzaffar
Khadija Ahmed
Faz Ashraf
Komal Zahid

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1590530

6,694 views
3 citations

Systematic Review

Published on 20 Jun 2025

A bibliometric analysis of global research hotspots and development trends in diabetic wound treatment

in Diabetes Therapies

Yin Wen
Kaiyu Nie

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1603206

2,429 views

Original Research

Published on 10 Jun 2025

The status and trends of type 2 diabetic osteoporosis research: a global bibliometric and visualization analysis over the past 20 years

in Diabetes Therapies

Haiyan Hou
Liying Zhu

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1596938

3,006 views

Original Research

Published on 16 Apr 2025

Design and methods of a multicenter randomized clinical trial of effects of diabetes-educated psychologist on glucose management and diabetes distress

in Diabetes Therapies

Johanna Zeijlemaker
Therese Anderbro
Sofia Sterner Isaksson
Marcus Lind

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1549234

1,534 views

Review

Published on 16 Apr 2025

Consumer-oriented review of digital diabetes prevention programs: insights from the CDC’s diabetes prevention recognition program

in Diabetes Therapies

Benjamin Lalani
Jalene Shim
Vidhu Vadini
Yllka Valdez
Daniel Zade
Nestoras Mathioudakis

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1562108

4,208 views
4 citations

Original Research

Published on 24 Mar 2025

Exploring factors predicting the effectiveness of oral semaglutide in Japanese individuals with type 2 diabetes switching from dipeptidyl peptidase 4 inhibitors: a pilot study

in Diabetes Therapies

Takao Hirotsu
Kanta Taniguchi
Rimei Nishimura

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2025.1520389

2,774 views

Opinion

Published on 09 Jan 2025

GLP-1 receptor agonists in diabetes and weight loss: the double-edged sword of innovation and risks

in Diabetes Therapies

Ioannis Ilias
Lina Zabuliene
Manfredi Rizzo

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2024.1530811

6,124 views
5 citations

Case Report

Published on 19 Dec 2024

Inhibition of leukotrienes and their potential role in type 1 diabetes pathogenesis: implications for montelukast as a therapeutic agent: a case report

in Diabetes Therapies

Pavel Fatulla
Ingela Ström
Christine Lingblom
Marcus Lind

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2024.1494470

2,258 views

Editorial

Published on 22 Apr 2024

Editorial: Diabetes, transplantation and regenerative medicine

in Diabetes Therapies

Alessandro Mattina
David Baidal
Braulio Marfil-Garza
Margherita Occhipinti
Valeria Sordi

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2024.1388904

2,313 views
1 citation

Original Research

Published on 19 Apr 2024

Effect of metformin adjunct therapy on cardiometabolic parameters in Indian adolescents with type 1 diabetes: a randomized controlled trial

in Diabetes Therapies

Shruti Mondkar
Sukeshini Khandagale
Nikhil Shah
Anuradha Khadilkar
Chirantap Oza
Shital Bhor
Ketan Gondhalekar
Aneeta Wagle
Neha Kajale
Vaman Khadilkar

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2024.1353279

3,064 views
3 citations

Original Research

Published on 13 Nov 2023

Impact of GAD65 and IA2 autoantibodies on islet allograft survival

in Diabetes Therapies

Joana R. N. Lemos
Raffaella Poggioli
Jonathan Ambut
Nujen C. Bozkurt
Ana M. Alvarez
Nathalia Padilla
Francesco Vendrame
Camillo Ricordi
David A. Baidal
Rodolfo Alejandro

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2023.1269758

2,873 views
4 citations

Original Research

Published on 31 Aug 2023

Incidence and predictors of mortality in children with diabetic ketoacidosis in the comprehensive specialized referral hospitals of West Amhara Region, Northwest Ethiopia: a retrospective follow-up study

in Diabetes Therapies

Rahel Asres Shimelash
Getaneh Mulualem Belay
Worknesh Aknaw
Aster Tadesse Shibabaw
Aderajew Agmas Adebabay
Gezahagn Demsu Gedefaw
Tadele Derbew Kassie
Alemu Birara Zemariam

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2023.1204133

4,943 views
10 citations

Original Research

Published on 30 May 2023

The clinical implications of fasting serum insulin levels in patients with insulin-treated type 2 diabetes: a cross-sectional survey

in Diabetes Therapies

Lingli Zhou
Yingying Luo
Yan Wang
Yao Cheng
Rui Zhang
Simin Zhang
Siqian Gong
Xueyao Han
Linong Ji

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2023.1172208

5,876 views
1 citation

Review

Published on 09 Mar 2023

Dopamine receptor agonists mechanism of actions on glucose lowering and their connections with prolactin actions

in Diabetes Therapies

Hung-Yu Chien
Su-Mei Chen
Wan-Chun Li

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2023.935872

17,250 views
23 citations

Original Research

Published on 03 Oct 2022

Aspalathin-rich green rooibos tea in combination with glyburide and atorvastatin enhances lipid metabolism in a db/db mouse model

in Diabetes Therapies

Oelfah Patel
Christo J. F. Muller
Elizabeth Joubert
Bernd Rosenkranz
Johan Louw
Charles Awortwe

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2022.963489

5,528 views
2 citations

Original Research

Published on 26 Jul 2022

Intensification of Insulin Treatment With Insulin Degludec/Aspart in Type 2 Diabetic Patients: A 2-Year Real-World Experience

in Diabetes Therapies

Hatice Oner
Hatice Gizem Gunhan
Dilek Gogas Yavuz

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2022.783277

2,887 views
1 citation

Original Research

Published on 05 Jul 2022

A Changed Gut Microbiota Diversity Is Associated With Metabolic Improvements After Duodenal Mucosal Resurfacing With Glucagon-Like-Peptide-1 Receptor Agonist in Type 2 Diabetes in a Pilot Study

in Diabetes Therapies

Suzanne Meiring
Annieke C. G. van Baar
Nikolaj Sørensen
Frits Holleman
Maarten R. Soeters
Max Nieuwdorp
Jacques J. G. H. M. Bergman

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2022.856661

4,956 views
13 citations

Original Research

Published on 12 Oct 2021

Dapagliflozin, as Add-on Therapy in Type 2 Diabetes Patients, Is Associated With a Reduction in Albuminuria and Serum Transaminase Levels

in Diabetes Therapies

Silas Benjamin
Manjunath Ramanjaneya
Alexandra E. Butler
Imran Janjua
Firjeeth Paramba
Jafer Palaki
Aisha Al Kubaisi
Prem Chandra
Ibrahem Abdalhakam
Nasseer Ahmad Massodi

Frontiers in Clinical Diabetes and Healthcare

doi 10.3389/fcdhc.2021.733693

2,652 views
2 citations

24 articles

articles

Real-world effectiveness and safety of imeglimin: a single-center retrospective cohort study in Japan

Editorial: Non-insulin pharmacotherapies for the treatment of type 2 diabetes and obesity - old and new players

Case Report: When genetic diagnosis comes late: lessons from a DEND syndrome patient successfully transitioned to sulfonylurea

Association between eating behavior patterns and the therapeutic efficacy of GLP-1 receptor agonists in individuals with type 2 diabetes: a multicenter prospective observational study

Therapeutic effects of Balanites aegyptiaca DEL extract on diabetes mellitus: a systematic review

GLP-1 receptor agonists and pancreatic beta cell apoptosis in diabetes mellitus: a systematic review and meta-analysis of preclinical studies

Exploring the multifaceted roles of GLP-1 receptor agonists; a comprehensive review

A bibliometric analysis of global research hotspots and development trends in diabetic wound treatment

The status and trends of type 2 diabetic osteoporosis research: a global bibliometric and visualization analysis over the past 20 years

Design and methods of a multicenter randomized clinical trial of effects of diabetes-educated psychologist on glucose management and diabetes distress

Consumer-oriented review of digital diabetes prevention programs: insights from the CDC’s diabetes prevention recognition program

Exploring factors predicting the effectiveness of oral semaglutide in Japanese individuals with type 2 diabetes switching from dipeptidyl peptidase 4 inhibitors: a pilot study

GLP-1 receptor agonists in diabetes and weight loss: the double-edged sword of innovation and risks

Inhibition of leukotrienes and their potential role in type 1 diabetes pathogenesis: implications for montelukast as a therapeutic agent: a case report

Editorial: Diabetes, transplantation and regenerative medicine

Effect of metformin adjunct therapy on cardiometabolic parameters in Indian adolescents with type 1 diabetes: a randomized controlled trial

Impact of GAD65 and IA2 autoantibodies on islet allograft survival

Incidence and predictors of mortality in children with diabetic ketoacidosis in the comprehensive specialized referral hospitals of West Amhara Region, Northwest Ethiopia: a retrospective follow-up study

The clinical implications of fasting serum insulin levels in patients with insulin-treated type 2 diabetes: a cross-sectional survey

Dopamine receptor agonists mechanism of actions on glucose lowering and their connections with prolactin actions

Aspalathin-rich green rooibos tea in combination with glyburide and atorvastatin enhances lipid metabolism in a db/db mouse model

Intensification of Insulin Treatment With Insulin Degludec/Aspart in Type 2 Diabetic Patients: A 2-Year Real-World Experience

A Changed Gut Microbiota Diversity Is Associated With Metabolic Improvements After Duodenal Mucosal Resurfacing With Glucagon-Like-Peptide-1 Receptor Agonist in Type 2 Diabetes in a Pilot Study

Dapagliflozin, as Add-on Therapy in Type 2 Diabetes Patients, Is Associated With a Reduction in Albuminuria and Serum Transaminase Levels