Frontiers in Digital Health | Personalized Medicine

Perspective

Accepted on 10 Dec 2025

Merging multimodal digital biomarkers into "Digital Neuro Fingerprints" for precision neurology in dementias: The promise of the right treatment for the right patient at the right time in the age of AI

in Personalized Medicine

Ioannis Tarnanas
Azizi Seixas
Martin Wyss
PANAGIOTIS VLAMOS
Arzu Coltekin

Frontiers in Digital Health

Review

Published on 18 Nov 2025

Digital twins in healthcare: a comprehensive review and future directions

in Personalized Medicine

Hamid Khoshfekr Rudsari
Becky Tseng
Hongxu Zhu
Lulu Song
Chunhui Gu
Abhishikta Roy
Ehsan Irajizad
Joseph Butner
James Long
Kim-Anh Do

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1633539

3,356 views

Study Protocol

Published on 08 Oct 2025

Digital home-based multimodal prehabilitation of colorectal cancer patients prior to surgery (the dHOPE study): a non-inferiority clinical trial protocol

in Personalized Medicine

Guro Kleve
Chiara Dalla Santa
Felicia Kristiansen
Marita Tegnander
Victoria Buch
Cecilie Steen Hagemann
Marianne Helgheim
Parasto Engene
Henri Pesonen
Maiken Kojen Kleveland

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1609678

4,345 views

Review

Published on 07 Aug 2025

Digital twin for personalized medicine development

in Personalized Medicine

Saniya Y. Saratkar
Meher Langote
Praveen Kumar
Pradnyawant Gote
Induni Nayodhara Weerarathna
Gaurav V. Mishra

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1583466

7,844 views
8 citations

Mini Review

Published on 10 Jul 2025

Next generation performance status: digital health technologies across the lung cancer continuum

in Personalized Medicine

Julia Scarpa
Iqram Hussain
Alex Cheng
Jonathan Villena-Vargas
Richard Boyer

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1558180

1,783 views
1 citation

Perspective

Published on 18 Jun 2025

Bridging clinic to home: domestic devices in dermatological diagnostics and treatments

in Personalized Medicine

Diala Haykal
Frederic Flament

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1595484

2,350 views
1 citation

Original Research

Published on 10 Jun 2025

Analysis of the level of polypharmacy in patients from an isolated rural area: effect of age, sex, and chronic diseases

in Personalized Medicine

Susana Abdala Kuri
Chaxiraxi Morales
Alexis M. Oliva
Adama Peña
Sandra Dévora

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1508505

1,605 views

Original Research

Published on 12 May 2025

Interpretable AI-driven multi-objective risk prediction in heart failure patients with thyroid dysfunction

in Personalized Medicine

Massimo Iacoviello
Vito Santamato
Alessandro Pagano
Agostino Marengo

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1583399

2,736 views
7 citations

Review

Published on 01 May 2025

Application of artificial intelligence and machine learning in lung transplantation: a comprehensive review

in Personalized Medicine

Xiting Liu
Wenqian Chen
Wenwen Du
Pengmei Li
Xiaoxing Wang

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1583490

3,265 views
3 citations

Original Research

Published on 30 Apr 2025

Comparison of the diagnostic concordance of tele-EMS and EMS physicians in the emergency medical service—a subanalysis of the TEMS-trial

in Personalized Medicine

Patrick P. Hess
Michael Czaplik
Johanna Hess
Hanna Schröder
Stefan K. Beckers
Andreas Follmann
Mark Pitsch
Marc Felzen

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1519619

2,209 views

Original Research

Published on 30 Apr 2025

The quest for blood pressure markers in photoplethysmography and its applications in digital health

in Personalized Medicine

Josep Sola
Andreu Arderiu
Tiago P. Almeida
Sibylle Fallet
Sasan Yazdani
Serj Haddad
David Perruchoud
Olivier Grossenbacher
Jay Shah

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1518322

5,027 views
1 citation

Systematic Review

Published on 04 Mar 2025

Global research landscape on nanotechnology in acute lung injury: a bibliometric analysis

in Personalized Medicine

Jian Zhang
Shasha Jiang
Jipeng Jiang
Yang Liu

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1472753

4,121 views
1 citation

Original Research

Published on 18 Feb 2025

Assessing accuracy of BiliPredics algorithm in predicting individual bilirubin progression in neonates—results from a prospective multi-center study

in Personalized Medicine

Britta Steffens
Gilbert Koch
Corinna Engel
Axel R. Franz
Marc Pfister
Sven Wellmann

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1497165

1,683 views
2 citations

Opinion

Published on 06 Feb 2025

The data scientist as a mainstay of the tumor board: global implications and opportunities for the global south

in Personalized Medicine

Myles Joshua Toledo Tan
Daniel Andrew Lichlyter
Nicholle Mae Amor Tan Maravilla
Weston John Schrock
Frederic Ivan Leong Ting
Joanna Marie Choa-Go
Kishi Kobe Francisco
Mickael Cavanaugh Byers
Hezerul Abdul Karim
Nouar AlDahoul

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1535018

5,654 views
6 citations

Review

Published on 23 Dec 2024

Artificial intelligence in respiratory care

in Personalized Medicine

Manjush Karthika
Jithin K. Sreedharan
Madhuragauri Shevade
Chris Sara Mathew
Santosh Ray

Frontiers in Digital Health

doi 10.3389/fdgth.2024.1502434

13,741 views
7 citations

Original Research

Published on 01 Nov 2024

A novel, machine-learning model for prediction of short-term ASCVD risk over 90 and 365 days

in Personalized Medicine

Tomer Gazit
Hanan Mann
Shiri Gaber
Pavel Adamenko
Granit Pariente
Liron Volsky
Amir Dolev
Helena Lyson
Eyal Zimlichman
Jay A. Pandit

Frontiers in Digital Health

doi 10.3389/fdgth.2024.1485508

4,306 views
1 citation

Editorial

Published on 25 Sep 2023

Editorial: Digital therapeutics: using software to treat, manage, and prevent disease

in Personalized Medicine

Kirsten E. Smayda
Tim Campellone
Sabrina R. Taylor
Brian Harris
Terry D. Ellis
Louis N. Awad

Frontiers in Digital Health

doi 10.3389/fdgth.2023.1261124

2,589 views

Editorial

Published on 20 Sep 2023

Editorial: Wearable and mobile data analysis methodologies for personalized medicine

in Personalized Medicine

Ivan Miguel Pires
Ciprian Dobre
Eftim Zdravevski
Nuno M. Garcia

Frontiers in Digital Health

doi 10.3389/fdgth.2023.1271659

1,904 views
1 citation

Mini Review

Published on 07 Sep 2023

Digital twin for healthcare systems

in Personalized Medicine

Alexandre Vallée

Frontiers in Digital Health

doi 10.3389/fdgth.2023.1253050

53,305 views
213 citations

General Commentary

Published on 31 Jul 2023

Commentary: Machine learning in clinical decision-making

in Personalized Medicine

Amanda C. Filiberto
Daniel A. Donoho
Ira L. Leeds
Tyler J. Loftus

Frontiers in Digital Health

doi 10.3389/fdgth.2023.1214111

2,234 views
4 citations

Original Research

Published on 22 Jun 2023

Association of digital measures and self-reported fatigue: a remote observational study in healthy participants and participants with chronic inflammatory rheumatic disease

in Personalized Medicine

Chaitra Rao
Elena Di Lascio
David Demanse
Nell Marshall
Monika Sopala
Valeria De Luca

Frontiers in Digital Health

doi 10.3389/fdgth.2023.1099456

6,072 views
10 citations

Brief Research Report

Published on 02 Jun 2023

Leveraging machine learning to examine engagement with a digital therapeutic

in Personalized Medicine

Andrew C. Heusser
Denton J. DeLoss
Elena Cañadas
Titiimaea Alailima

Frontiers in Digital Health

doi 10.3389/fdgth.2023.1063165

3,294 views
4 citations

Clinical Trial

Published on 23 May 2023

A CBT-based mobile intervention as an adjunct treatment for adolescents with symptoms of depression: a virtual randomized controlled feasibility trial

in Personalized Medicine

Vera N. Kulikov
Phoebe C. Crosthwaite
Shana A. Hall
Jessica E. Flannery
Gabriel S. Strauss
Elise M. Vierra
Xin L. Koepsell
Jessica I. Lake
Aarthi Padmanabhan

Frontiers in Digital Health

doi 10.3389/fdgth.2023.1062471

12,977 views
18 citations

Original Research

Published on 19 May 2023

Hypoglycemia risk with physical activity in type 1 diabetes: a data-driven approach

in Personalized Medicine

Sahana Prasanna
Souptik Barua
Alejandro F. Siller
Jeremiah J. Johnson
Ashutosh Sabharwal
Daniel J. DeSalvo

Frontiers in Digital Health

doi 10.3389/fdgth.2023.1142021

5,743 views
4 citations

84 articles

articles

Merging multimodal digital biomarkers into "Digital Neuro Fingerprints" for precision neurology in dementias: The promise of the right treatment for the right patient at the right time in the age of AI

Digital twins in healthcare: a comprehensive review and future directions

Digital home-based multimodal prehabilitation of colorectal cancer patients prior to surgery (the dHOPE study): a non-inferiority clinical trial protocol

Digital twin for personalized medicine development

Next generation performance status: digital health technologies across the lung cancer continuum

Bridging clinic to home: domestic devices in dermatological diagnostics and treatments

Analysis of the level of polypharmacy in patients from an isolated rural area: effect of age, sex, and chronic diseases

Interpretable AI-driven multi-objective risk prediction in heart failure patients with thyroid dysfunction

Application of artificial intelligence and machine learning in lung transplantation: a comprehensive review

Comparison of the diagnostic concordance of tele-EMS and EMS physicians in the emergency medical service—a subanalysis of the TEMS-trial

The quest for blood pressure markers in photoplethysmography and its applications in digital health

Global research landscape on nanotechnology in acute lung injury: a bibliometric analysis

Assessing accuracy of BiliPredics algorithm in predicting individual bilirubin progression in neonates—results from a prospective multi-center study

The data scientist as a mainstay of the tumor board: global implications and opportunities for the global south

Artificial intelligence in respiratory care

A novel, machine-learning model for prediction of short-term ASCVD risk over 90 and 365 days

Editorial: Digital therapeutics: using software to treat, manage, and prevent disease

Editorial: Wearable and mobile data analysis methodologies for personalized medicine

Digital twin for healthcare systems

Commentary: Machine learning in clinical decision-making

Association of digital measures and self-reported fatigue: a remote observational study in healthy participants and participants with chronic inflammatory rheumatic disease

Leveraging machine learning to examine engagement with a digital therapeutic

A CBT-based mobile intervention as an adjunct treatment for adolescents with symptoms of depression: a virtual randomized controlled feasibility trial

Hypoglycemia risk with physical activity in type 1 diabetes: a data-driven approach