Frontiers in Drug Discovery

Mini Review

Published on 02 Feb 2024

Deep generative models in the quest for anticancer drugs: ways forward

in In silico Methods and Artificial Intelligence for Drug Discovery

Virgilio Romanelli
Carmen Cerchia
Antonio Lavecchia

Frontiers in Drug Discovery

doi 10.3389/fddsv.2024.1362956

1,873 views
1 citation

Mini Review

Published on 31 Jan 2024

The case of the missing mouse—developing cystic fibrosis drugs without using animals

in Technologies and Strategies to Enable Drug Discovery

Lindsay J. Marshall
Kathleen M. Conlee

Frontiers in Drug Discovery

doi 10.3389/fddsv.2024.1347246

1,915 views

Mini Review

Published on 25 Jan 2024

Identification of first active compounds in drug discovery. how to proceed?

in Technologies and Strategies to Enable Drug Discovery

Stéphane Giraud

Frontiers in Drug Discovery

doi 10.3389/fddsv.2024.1342866

4,013 views
2 citations

Original Research

Published on 18 Dec 2023

Global proteomics insights for a novel small compound targeting the non-integrin Laminin Receptor in a macrophage cell model

in Anti-inflammatory and Immunomodulating Agents

Abigail Haffner
Manoel Figueiredo Neto
C. Samuel Umbaugh
Tiago J. P. Sobreira
Timothy B. Lescun
Herman O. Sintim
Marxa L. Figueiredo

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1326736

1,612 views
2 citations

Review

Published on 15 Dec 2023

Targeting mitochondrial metabolites and nucleic acids as an anti-inflammatory strategy

in Anti-inflammatory and Immunomodulating Agents

Yukun Min
Luke A. J. O’Neill

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1294454

2,158 views
1 citation

Case Report

Published on 11 Dec 2023

Case report: C-reactive protein apheresis in cardiogenic shock: case series from the C-reactive protein apheresis in acute myocardial infarction-registry

in Anti-inflammatory and Immunomodulating Agents

J. Torzewski
S. Mattecka
W. Ries
C. D. Garlichs
F. Heigl
J. Fiedler
A. Sheriff

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1286710

2,504 views
4 citations

Original Research

Published on 11 Dec 2023

Consensus docking aid to model the activity of an inhibitor of DNA methyltransferase 1 inspired by de novo design

in In silico Methods and Artificial Intelligence for Drug Discovery

Diana L. Prado-Romero
Alejandro Gómez-García
Raziel Cedillo-González
Hassan Villegas-Quintero
Juan F. Avellaneda-Tamayo
Edgar López-López
Fernanda I. Saldívar-González
Ana L. Chávez-Hernández
José L. Medina-Franco

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1261094

4,000 views
6 citations

Editorial

Published on 08 Dec 2023

Editorial: Drug discovery for emerging and neglected tropical diseases: advances, challenges and perspectives

in Anti-Infective Agents

Laura Alcântara
Caio Franco
Nilmar Moretti
Denise Pilger

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1346042

1,177 views

Review

Published on 01 Dec 2023

Latest development of approved COVID-19 drugs and COVID-19 drugs undergoing late stage clinical trials

in Anti-Infective Agents

Bingru Feng
Kai Fu

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1304129

3,002 views
3 citations

Mini Review

Published on 30 Nov 2023

Introduction to small molecule drug discovery and preclinical development

in Technologies and Strategies to Enable Drug Discovery

Michelle W. Y. Southey
Michael Brunavs

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1314077

52,479 views
32 citations

Mini Review

Published on 27 Nov 2023

HyBryte™ use in early-stage cutaneous T-cell lymphoma

in Dermatologic Drugs

Brian Poligone
Carolina V. Alexander-Savino
Ellen J. Kim
Aaron R. Mangold
Jennifer Desimone
Henry K. Wong
Adam T. Rumage
Oreola Donini
Andrea Haulenbeek
Christopher J. Schaber

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1298453

2,395 views

Editorial

Published on 23 Nov 2023

Editorial: Advances in anti-malarial drug discovery

in Anti-Infective Agents

Agam Prasad Singh
Brijesh Rathi

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1335842

1,350 views
2 citations

Original Research

Published on 22 Nov 2023

Targeting a cancer-specific LYPD3 glycoform for tumor therapy

in Anti-Cancer Drugs

Theresa Neumann
Evelyn Hartung
Johanna Gellert
Lisa Weiß
Manon Weiske
Naomi Kast
Stephanie Gurka
Sophie Marinoff
Anika Jäkel
Antje Danielczyk

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1298916

3,189 views
1 citation

Review

Published on 21 Nov 2023

Future treatments for the arteriopathy of ectopic calcification disorders

in Cardiovascular and Hematologic Drugs

Benjamin M. Davies
Frank Rutsch
Naren Vyavahare
Alexander Jones

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1249966

2,179 views

Original Research

Published on 14 Nov 2023

In vitro drug interaction of ionophores with artemisinin and chloroquine against Plasmodium falciparum 3D7 blood-stage infection

in Anti-Infective Agents

Vinoth Rajendran
Keerthana Gurukkalot

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1257698

1,635 views
1 citation

Original Research

Published on 30 Oct 2023

An improved method for large scale generation and high-throughput functional characterization of human iPSC-derived microglia

in Technologies and Strategies to Enable Drug Discovery

Manisha Padmakumar
Steven Biesmans
Jorge S. Valadas
Jan R. Detrez
Gaëlle Gillet
Priscillia Bresler
Marie-Laure Clénet
Irena Kadiu

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1289314

2,718 views