Frontiers in Drug Discovery

Case Report

Published on 11 Dec 2023

Case report: C-reactive protein apheresis in cardiogenic shock: case series from the C-reactive protein apheresis in acute myocardial infarction-registry

in Anti-inflammatory and Immunomodulating Agents

J. Torzewski
S. Mattecka
W. Ries
C. D. Garlichs
F. Heigl
J. Fiedler
A. Sheriff

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1286710

2,230 views
2 citations

Editorial

Published on 08 Dec 2023

Editorial: Drug discovery for emerging and neglected tropical diseases: advances, challenges and perspectives

in Anti-Infective Agents

Laura Alcântara
Caio Franco
Nilmar Moretti
Denise Pilger

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1346042

926 views

Review

Published on 01 Dec 2023

Latest development of approved COVID-19 drugs and COVID-19 drugs undergoing late stage clinical trials

in Anti-Infective Agents

Bingru Feng
Kai Fu

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1304129

2,352 views
1 citation

Mini Review

Published on 30 Nov 2023

Introduction to small molecule drug discovery and preclinical development

in Technologies and Strategies to Enable Drug Discovery

Michelle W. Y. Southey
Michael Brunavs

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1314077

34,327 views
17 citations

Mini Review

Published on 27 Nov 2023

HyBryte™ use in early-stage cutaneous T-cell lymphoma

in Dermatologic Drugs

Brian Poligone
Carolina V. Alexander-Savino
Ellen J. Kim
Aaron R. Mangold
Jennifer Desimone
Henry K. Wong
Adam T. Rumage
Oreola Donini
Andrea Haulenbeek
Christopher J. Schaber

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1298453

2,045 views

Editorial

Published on 23 Nov 2023

Editorial: Advances in anti-malarial drug discovery

in Anti-Infective Agents

Agam Prasad Singh
Brijesh Rathi

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1335842

1,056 views
1 citation

Original Research

Published on 22 Nov 2023

Targeting a cancer-specific LYPD3 glycoform for tumor therapy

in Anti-Cancer Drugs

Theresa Neumann
Evelyn Hartung
Johanna Gellert
Lisa Weiß
Manon Weiske
Naomi Kast
Stephanie Gurka
Sophie Marinoff
Anika Jäkel
Antje Danielczyk

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1298916

2,690 views
1 citation

Review

Published on 21 Nov 2023

Future treatments for the arteriopathy of ectopic calcification disorders

in Cardiovascular and Hematologic Drugs

Benjamin M. Davies
Frank Rutsch
Naren Vyavahare
Alexander Jones

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1249966

1,731 views

Original Research

Published on 14 Nov 2023

In vitro drug interaction of ionophores with artemisinin and chloroquine against Plasmodium falciparum 3D7 blood-stage infection

in Anti-Infective Agents

Vinoth Rajendran
Keerthana Gurukkalot

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1257698

1,237 views

Original Research

Published on 30 Oct 2023

An improved method for large scale generation and high-throughput functional characterization of human iPSC-derived microglia

in Technologies and Strategies to Enable Drug Discovery

Manisha Padmakumar
Steven Biesmans
Jorge S. Valadas
Jan R. Detrez
Gaëlle Gillet
Priscillia Bresler
Marie-Laure Clénet
Irena Kadiu

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1289314

2,023 views

Review

Published on 18 Sep 2023

State-of-the-art strategies to prioritize Mycobacterium tuberculosis drug targets for drug discovery using a subtractive genomics approach

in In silico Methods and Artificial Intelligence for Drug Discovery

Adetutu Akinnuwesi
Samuel Egieyeh
Ruben Cloete

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1254656

1,862 views
1 citation

Mini Review

Published on 05 Sep 2023

Harnessing bioluminescence for drug discovery and epigenetic research

in Technologies and Strategies to Enable Drug Discovery

Hannah J. Gleneadie
Andrew Dimond
Amanda G. Fisher

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1249507

2,691 views
2 citations

Brief Research Report

Published on 03 Aug 2023

Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics

in Anti-Cancer Drugs

Ida Lin
Peter B. Rupert
Kristina Pilat
Raymond O. Ruff
Della J. Friend
Man Kid Chan
Midori Clarke
Benjamin G. Hoffstrom
Jane Carter
Soheil Meshinchi

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1216516

3,786 views
3 citations

Review

Published on 25 Jul 2023

The importance of good practices and false hits for QSAR-driven virtual screening real application: a SARS-CoV-2 main protease (Mpro) case study

in In silico Methods and Artificial Intelligence for Drug Discovery

Mateus Sá Magalhães Serafim
Simone Queiroz Pantaleão
Elany Barbosa da Silva
James H. McKerrow
Anthony J. O’Donoghue
Bruno Eduardo Fernandes Mota
Kathia Maria Honorio
Vinícius Gonçalves Maltarollo

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1237655

2,124 views
4 citations

Original Research

Published on 20 Jul 2023

9-PAHSA displays a weak anti-inflammatory potential mediated by specific antagonism of chemokine G protein-coupled receptors

in Anti-inflammatory and Immunomodulating Agents

Paulus Wohlfart
Mounir Chehtane
Ernesto Luna
Riyaz Mehta
Marcus Korn
Anish Konkar
Uwe Schwahn
Stefan Petry
Norbert Tennagels
Maximilian Bielohuby

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1138461

2,100 views

Review

Published on 13 Jul 2023

Targeting proteases and proteolytic processing of unusual N-terminal extensions of Plasmodium proteins: parasite peculiarity

in Anti-Infective Agents

Ankita Tehlan
Abhik Saha
Suman Kumar Dhar

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1223140

1,562 views

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Articles

Case report: C-reactive protein apheresis in cardiogenic shock: case series from the C-reactive protein apheresis in acute myocardial infarction-registry

Editorial: Drug discovery for emerging and neglected tropical diseases: advances, challenges and perspectives

Latest development of approved COVID-19 drugs and COVID-19 drugs undergoing late stage clinical trials

Introduction to small molecule drug discovery and preclinical development

HyBryte™ use in early-stage cutaneous T-cell lymphoma

Editorial: Advances in anti-malarial drug discovery

Targeting a cancer-specific LYPD3 glycoform for tumor therapy

Future treatments for the arteriopathy of ectopic calcification disorders

In vitro drug interaction of ionophores with artemisinin and chloroquine against Plasmodium falciparum 3D7 blood-stage infection

An improved method for large scale generation and high-throughput functional characterization of human iPSC-derived microglia

State-of-the-art strategies to prioritize Mycobacterium tuberculosis drug targets for drug discovery using a subtractive genomics approach

Harnessing bioluminescence for drug discovery and epigenetic research

Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics

The importance of good practices and false hits for QSAR-driven virtual screening real application: a SARS-CoV-2 main protease (Mpro) case study

9-PAHSA displays a weak anti-inflammatory potential mediated by specific antagonism of chemokine G protein-coupled receptors

Targeting proteases and proteolytic processing of unusual N-terminal extensions of Plasmodium proteins: parasite peculiarity