Original Research
Accepted on 26 Dec 2025
Across pre-clinical and clinical platforms, approved and investigational psychiatric drugs share pathways and associate with similar molecular functions
Frontiers in Drug Discovery
152 Publications
volumes
Volume 5 - 2025
Original Research
Accepted on 16 Dec 2025
Enhancing Structure-Based Virtual Screening of MDM2–p53 Inhibitors: A Benchmark of Machine Learning vs. Traditional Docking Scoring Functions
Frontiers in Drug Discovery
- 234 views
Brief Research Report
Accepted on 12 Dec 2025
Dual RNA Polymerase I Inhibition with CX-5461 and BMH-21 Synergizes in Breast Cancer by Activating p53-Dependent Stress
Frontiers in Drug Discovery
- 179 views
Original Research
Published on 10 Dec 2025
A network-based protocol to prioritize compounds for biological testing: discovery of Anti-Staphylococcus aureus cacalol derivatives
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1724392
- 685 views
Review
Published on 10 Dec 2025
Exploring deep learning approaches in anticancer drug design: a review of recent advances
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1713308
- 869 views
Original Research
Accepted on 09 Dec 2025
Multivalent display of membrane proteins using HIV1-Gag VLPs
Frontiers in Drug Discovery
- 140 views
Study Protocol
Published on 09 Dec 2025
Integrated in vivo and in silico evaluation of antimalarial compounds from Vernonia ambigua leaves identified by GC-MS profiling
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1635697
- 552 views
Specialty Grand Challenge
Accepted on 05 Dec 2025
Grand Challenges in Dermatologic Drug Discovery: Four Priorities to Transform Skin Disease Treatment
Frontiers in Drug Discovery
- 398 views
Original Research
Published on 10 Nov 2025
Towards human cardiac new approach methodologies (NAMs) to evaluate the combination of repolarization prolonging and shortening drugs: a pilot study
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1679626
- 1,103 views
Original Research
Published on 17 Sep 2025
Influence of divalent metal ions on gelation of a short heterochiral peptide
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1673051
- 1,141 views
Original Research
Published on 10 Sep 2025
Bioinformatics-driven identification and prioritization of PTSD targets based on published multi-omic data
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1613261
- 1,694 views
Perspective
Published on 03 Sep 2025
Advancing histone deacetylase 6 (HDAC6) as a promising therapeutic target for Alzheimer’s disease: from molecular insights to clinical prospects
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1662691
- 3,510 views
Opinion
Published on 25 Aug 2025
On the biologically relevant chemical space: BioReCS
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1674289
- 3,270 views
- 3 citations
Mini Review
Published on 26 Jun 2025
AI-driven innovation in antibody-drug conjugate design
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1628789
- 9,258 views
- 8 citations
Editorial
Published on 10 Jun 2025
Editorial: Pharmacokinetics modeling in the Artificial Intelligence Era
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1636070
- 1,958 views
Original Research
Published on 06 Jun 2025
Dual upregulation of miRNA-143 and miRNA-506 in non-small cell lung cancer inhibits proliferation, motility, migration, and tumor growth
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1584801
- 2,205 views
Editorial
Published on 04 Jun 2025
Editorial: Enhancing drug discovery through structure-based design and computational techniques
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1632015
- 2,095 views
Original Research
Published on 30 May 2025
Safety and tolerability of a bevacizumab biosimilar (Effivia®) in adult Mexican patients with cancer: a multicenter, observational, prospective clinical study
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1591991
- 1,692 views
Original Research
Published on 15 Apr 2025
Identification of natural compounds as potential inhibitors of Interleukin-23: virtual screening, ADMET, drug-likeness, and dynamic simulation
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1525533
- 2,981 views
- 9 citations
Original Research
Published on 21 Feb 2025
Transduction of hematopoietic stem and progenitor cells by an MECP2 lentiviral vector improves Rett syndrome phenotypes
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1545391
- 2,349 views
Editorial
Published on 20 Feb 2025
Editorial: Exploring drug development with single cell omics analytics and stem cell-based disease models
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1561985
- 1,532 views
Perspective
Published on 19 Feb 2025
Perspective: How complex in vitro models are addressing the challenges of predicting drug-induced liver injury
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1536756
- 5,313 views
- 4 citations
Review
Published on 29 Jan 2025
Non-enzymatic protein targeting agents as a promising strategy for cancer treatment
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1520734
- 5,782 views