Frontiers in Endocrinology

Original Research

Published on 19 Dec 2025

Risk factors for denosumab-related osteonecrosis of the jaw: a pharmacovigilance study using the U.S. FDA adverse event reporting system database

in Bone Research

Hehe Bai
Jinping Wang
Xiaonian Han
Huan Li
Xiaojing Nie
Guan Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1586626

1,870 views

Original Research

Published on 15 Dec 2025

Exploring the mechanism of Heidihuang Pill in the treatment of osteoporosis based on network pharmacology, molecular docking, and experimental validation

in Bone Research

Zenghui Tian
Kaiying Cui
Yuxiao Tian
Yungang Chen
Guoyan Liu
Farong Zhang
Yanke Hao
Yingying Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1664254

1,217 views

Original Research

Published on 15 Dec 2025

Performance of USPSTF-recommended osteoporosis risk assessment tools in identifying osteoporosis in older men: a multicentre retrospective study

in Bone Research

Xin Li
Dongsheng Guo
Chen Yan
Mingran Luo
Yixin Liang
Jian Zhang
Lin Cheng
Yuefu Dong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1729945

1,081 views

Original Research

Published on 12 Dec 2025

Gut microbiota dysbiosis affects the local renin-angiotensin system to induce osteoporosis

in Bone Research

Kai Zhong
Yuanhui Wang
Pengkun Han
Zhanwen Huang
Zonghui Xie
Peigeng Yu
Hanwen Liu
Hao Hu
Meiyun Tan
Xing Guo

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1698719

1,109 views

Original Research

Published on 12 Dec 2025

Bone mineral density assessment according to Italian essential assistance levels: a positive predictive value analysis based on administrative data

in Bone Research

Veronica Abate
Anita Vergatti
Guido Cavati
Simone Magelli
Alfonso Varriale
Daniela Merlotti
Gianpaolo De Filippo
Gaetano Piccinocchi
Lanfranco D’Elia
Luigi Gennari

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1689549

830 views

Review

Published on 12 Dec 2025

Selenium-containing nanoparticles and bone related disorders: from synthesis, bone metabolism to disease therapy

in Bone Research

Ziyang Yue
Haonan Li
Yi Hu
Jinshen Shen

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1724888

1,655 views

Review

Published on 11 Dec 2025

Osteosarcopenia in metabolic dysfunction–associated steatotic liver disease: from mechanisms to management

in Bone Research

Aili Fan
Jie Zhang
Qing Ye

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1706068

1,722 views

Review

Published on 10 Dec 2025

The effect of non-pharmacological interventions on bone health among patients with low bone mass: a systematic review and meta-analysis

in Bone Research

Xiaona Na
Yucheng Yang
Huanhuan Yang
Zekun Chen
Xiaochen Qu
Jian Zhang
Mo Chen
Dantong Wang
Denis Breuille
Kai Yu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1612739

1,742 views

Review

Published on 09 Dec 2025

Functional hypothalamic amenorrhea in adolescent athletes impairs bone accrual and increases fracture risk

in Bone Research

Laurel Wong
Lily Leibner
Camila Vicioso
Bina Shah
Sheena C. Ranade

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1709695

2,260 views

Correction

Published on 08 Dec 2025

Correction: A threshold of β-CTX (0.3 ng/mL) with low estradiol identifies high-risk perimenopausal women for bone loss: a cross-sectional study

in Bone Research

Xufen Feng
Wenjun Xiao
Rongshan Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1756303

617 views

Original Research

Published on 05 Dec 2025

The relationship between serum total alkaline phosphatase and risk of osteoporosis: a cross-sectional study

in Bone Research

Yuang Chen
Yong Zhang
Mao Nie

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1657631

2,620 views

Original Research

Published on 04 Dec 2025

Can vitamin D supplementation be dangerous? 25-Hydroxyvitamin D and 1,25-hydroxyvitamin D concentration in healthy population and primary hyperparathyroidism: a single-center experience and literature review

in Bone Research

Łukasz Obołończyk
Monika Berendt-Obołończyk
Krzysztof Sworczak
Izabela Karwacka-Bujak
Ewa Majerowska
Marcin Renke

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1700345

1,375 views
1 citation

Review

Published on 03 Dec 2025

Targeting chemokine signaling networks for therapeutics in skeletal disorders

in Bone Research

Wenjie Gao
Zhiheng Gao
Yu Chen
Yu Wang
Yonggang Li
Yuchen Qian
Haowen Lu
Xuwei Ling
Heting Xiao
Peng Yang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1667440

2,102 views

Review

Published on 01 Dec 2025

Application of circadian rhythm in osteoporosis prevention and treatment: from light, diet, and exercise to chronotherapy

in Bone Research

Jun Qian
Kai Huang
Qiaocheng Zhai

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1698016

1,625 views

Review

Published on 27 Nov 2025

G-protein coupled receptors synergy in bone health: new avenues for osteoporosis detection and in vitro modeling

in Bone Research

Julia V. Sopova
Olga A. Krasnova
Julia D. Kriukova
Yana O. Mukhamedshina
Elena Y. Zakirova
Albert A. Rizvanov
Olga M. Lesnyak
Irina E. Neganova

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1684658

1,403 views

Original Research

Published on 26 Nov 2025

Osteocalcin in human breast milk over the course of lactation

in Bone Research

Olivier Prosperi
Beatrice Hanusch
Sophia Naber
Thomas Lücke
Kathrin Sinningen

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1715553

1,098 views

Original Research

Published on 25 Nov 2025

Correlation of body compositions and bone mineral density in postmenopausal women with different body mass index

in Bone Research

Song Ge
Min Li
Xiaoxue Bao
Gege Wu
Mengcong Liu
Wei Zhang
Yukun Li
Yan Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1642801

1,199 views

Original Research

Published on 25 Nov 2025

Biochemical evaluation of X-linked hypophosphatemia and tumor-induced osteomalacia: insights into diagnosis and management

in Bone Research

Jorge Díaz-Garzón Marco
Pilar Aguado Acín
Esteban Jodar Gimeno
Pilar Fernández Calle
Vanessa Lopes Martín
María Luisa González-Casaus

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1702656

1,796 views

Systematic Review

Published on 25 Nov 2025

Fatty infiltration and cross-sectional area as indicators of muscle mass in osteoporosis: a meta-regression study

in Bone Research

Genwen Sun
Yuee Dai
Liu Liu
Yu Du
Ping Jiang
Xiangkui Li
Chao Li
Tao Lin

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1651505

1,358 views

Original Research

Published on 25 Nov 2025

The predictive value of 24-hour urinary calcium for kidney stone risk in primary hyperparathyroidism: insight from a retrospective study of parathyroid adenoma cases

in Bone Research

Arti Bhan
Rebecca Simon
Aseel Yaseen
Bernard Cook
Shijing Qiu
Sudhaker D. Rao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1671905

1,227 views

Review

Published on 24 Nov 2025

Novel aspects of biochemical assessment of bone remodeling and mineralization

in Bone Research

Dorota Leszczyńska
Alicja Szatko
Agata Toboła
Katarzyna Karoń
Waldemar Misiorowski
Piotr Glinicki
Wojciech Zgliczyński

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1702413

1,922 views

Original Research

Published on 24 Nov 2025

Efficacy and safety of prophylactic intravenous calcium supplementation in patients with secondary hyperparathyroidism after parathyroidectomy: a retrospective study

in Bone Research

Yao Pan
Jiaqi Zhu
Zhenglong Wu
Dengfeng Wu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1652418

851 views

Review

Published on 21 Nov 2025

Macrophages in osteoporotic fractures: from immunometabolic mechanisms to precision therapeutic approaches

in Bone Research

Jiahui Xing
Haibo Li
Honggang Xia
Lilei Xia
Hongzhou Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1698647

1,891 views

Original Research

Published on 21 Nov 2025

Association of baseline osteocalcin and femoral neck bone mineral density in healthy women with future risk of fractures, cardiovascular disease, diabetes and death

in Bone Research

Zheng-Can Pan
Yu-Ying Yang
Xiao-Jing Chen
Tao Jiang
Jia-Xi Song
Chun-Xiang Sheng
Yi-Zhu Wang
Min Xu
Yan-Hua Deng
Guang-Ping Yu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1652769

1,204 views