Frontiers in Endocrinology | Diabetes: Molecular Mechanisms

Correction

Published on 17 Nov 2025

Correction: Single-cell profiling reveals transcriptomic signatures of vascular endothelial cells in non-healing diabetic foot ulcers

in Diabetes: Molecular Mechanisms

Yangzhou Lu
Xiaogang Liu
Jingling Zhao
Fan Bie
Yiling Liu
Julin Xie
Peng Wang
Junyou Zhu
Yahui Xiong
Shitian Qin

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1714094

597 views

Editorial

Published on 13 Nov 2025

Editorial: In vivo magnetic resonance imaging of metabolic disorders

in Diabetes: Molecular Mechanisms

An Tang
Martin Lepage
Guy A. Rutter
André C. Carpentier

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1713999

1,027 views

Original Research

Published on 11 Nov 2025

Multi level effects of Sanghuang Tongxie Formula on type 2 diabetes rats: a comprehensive analysis from intestinal bacteria to metabolome and transcriptome

in Diabetes: Molecular Mechanisms

Jiaxuan Liu
Sufen Bai
Chenxi Wu
Chunyu Tian
Qianru Fu
Xiujuan Gao
Biwei Zhang
Ji’an Li
Xiumei Cheng
Xiaojin La

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1562105

2,224 views

Systematic Review

Accepted on 10 Nov 2025

Genetic Landscape of Neonatal Diabetes Mellitus (NDM) in the Middle East, North Africa, and Türkiye (MENAT): A Systematic Review

in Diabetes: Molecular Mechanisms

Salma Younes
Faisal Elmi Ibrahim
Ofelia Masoud
Sara Awwad
Halah Noor Nasir
Hatem Zayed
Nader Al-Dewik

Frontiers in Endocrinology

222 views

Original Research

Published on 07 Nov 2025

Sodium-glucose cotransporter 2 inhibitors—but not insulin—enhance renal branched-chain amino acid catabolism

in Diabetes: Molecular Mechanisms

Moeko Sakamoto
Nao Hasuzawa
Lixiang Wang
Kyoko Tashiro
Miyuki Kitamura
Shimpei Iwata
Nobuhiko Wada
Seiji Nomura
Sawako Moriyama
Mizuki Gobaru

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1706838

2,348 views
1 citation

Original Research

Published on 07 Nov 2025

MicroRNAs modulated by DPP-4 inhibitor and bedtime NPH insulin therapy in individuals with type 2 diabetes

in Diabetes: Molecular Mechanisms

Aritania Sousa Santos
Silvia Yumi Bando
Maria Lucia Cardillo Correa Giannella
Maria Elizabeth Rossi da Silva

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1706951

2,254 views

Review

Published on 06 Nov 2025

Diabetic kidney disease macrophage cholesterol efflux: a revolution from metabolism to immune

in Diabetes: Molecular Mechanisms

Jinjin Wang
Yi Cai
Yuxi Feng
Qin Zhu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1714167

3,649 views

Review

Published on 05 Nov 2025

The role of dysregulated copper metabolism in diabetes and its complications: a review

in Diabetes: Molecular Mechanisms

Chen Wang
Junhong Wu
Yan Wang
Chengcheng Huang
Mengjuan Wei
Yufei Zhang
Renchu Shen
Jingwu Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1681001

2,139 views
2 citations

Original Research

Published on 05 Nov 2025

Association of TNF-α polymorphisms rs1800629 (−308G>A) and rs361525 (−238G>A) with type 2 diabetes mellitus in the Punjabi population of Pakistan

in Diabetes: Molecular Mechanisms

Muhammad Waqar
Tsai-Sung Tai
Abdul Qadeer
Umar Aziz
Mohammad Abohassan
Chien-Chin Chen
Sawar Khan

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1664411

1,713 views

Original Research

Published on 03 Nov 2025

Comprehensive transcriptomic profiling reveals tissue-specific molecular signatures and dysregulated pathways in human diabetic foot ulcers

in Diabetes: Molecular Mechanisms

Guangrong Hu
Ayesha Nisar
Sawar Khan
Wen Li
Enfang Zhu
Haoling Cui
Guiqin Zhang
Yonghan He
Hui Sun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1669205

2,589 views
1 citation

Original Research

Published on 03 Nov 2025

U-TXM: a novel biomarker for early detection of diabetic kidney disease

in Diabetes: Molecular Mechanisms

Yujie Jin
Jiahao Xu
Yan Ma
Chunchen Ni
Yan Yao
Shujuan Shang
Mengru Wang
Chunyan Xing
Song Dong
Chaoqun Xiong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1682136

1,274 views

Original Research

Published on 31 Oct 2025

Deciphering the epigenetic role of KDM4A in pancreatic β-like cell differentiation from iPSCs

in Diabetes: Molecular Mechanisms

Felipe Arroyave
Lina Méndez-Castillo
Fernando Lizcano

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1697097

1,264 views

Original Research

Published on 31 Oct 2025

Genetic/epigenetic RNA dysregulation in type 2 diabetes mellitus complicated with ischemic heart disease

in Diabetes: Molecular Mechanisms

Eslam S. Sedkey
Marwa Matboli
Mohamed G. Seadawy
Marwa G.A. Hegazy

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1687145

1,546 views

Systematic Review

Published on 30 Oct 2025

Yerba Maté and its impact on glycemic control and metabolic health: a systematic review and meta-analysis

in Diabetes: Molecular Mechanisms

Daiping Li
Liantian Yue
Xuchao Peng
Ling Chen
Taiping Lin
Li Huang
Yadong Liu
Jirong Yue
Xiaoli Huang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1641592

3,753 views

Original Research

Published on 29 Oct 2025

Identification and validation of key mitophagy-related biomarkers in the pathogenesis of proliferative diabetic retinopathy

in Diabetes: Molecular Mechanisms

Yifan Liu
Ye Zhou
Jie Chen
Jiahui Jin
Xueying Wang
Xi Wang
Jieping Zhang
Jiao Li
Junfang Zhang
Ling Zhu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1652898

1,660 views

Original Research

Published on 28 Oct 2025

Allyl nonanoate as a novel bile-derived biomarker in metabolic dysfunction-associated steatotic liver disease

in Diabetes: Molecular Mechanisms

Soo Hyeon Lee
Jonghwan Kim
Sung Ryol Lee
Bum Soo Lee
Ki Hyun Kim
Dae Won Jun
Chung Sub Kim
Kyung A Kang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1707492

1,915 views
1 citation

Original Research

Published on 22 Oct 2025

MODY PDX1P33T: a mouse model reveals phenotypic divergence from human disease

in Diabetes: Molecular Mechanisms

Aliona Harten
Maximilian R. Schmidtke
Florian Giesert
David A. Skerrett-Byrne
Raffaele Teperino
Gerhard K. H. Przemeck
Martin Hrabě de Angelis

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1680893

1,843 views

Original Research

Published on 15 Oct 2025

Growth factor and hypoxia-inducible factor alpha content in the retina of male Wistar rats in experimental diabetic retinopathy and the effect of cellular protein kinase blockade

in Diabetes: Molecular Mechanisms

K. O. Usenko
Olena Strubchevska
S. O. Rykov
M. S. Babenko
Kateryna Strubchevska
Oleksandra Kozyk
S. V. Ziablitsev
Marko Kozyk

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1643445

1,662 views

Original Research

Published on 15 Oct 2025

BRI is an independent predictor of new-onset kidney stones in a non-diabetic population: a retrospective analysis

in Diabetes: Molecular Mechanisms

Xiaohong Fan
Si Yu
Jing Li
Songbai Lin
Sanxi Ai
Haiting Wu
Yunyun Fei
Yan Qin
Gang Chen
Xuemei Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1686183

1,746 views

Editorial

Published on 14 Oct 2025

Editorial: The impact of GIP/GIPR on metabolic diseases: how the field is evolving

in Diabetes: Molecular Mechanisms

Kirk Habegger
Alejandra Tomas
Roger Chen
Charles Harris
William Roell
Tamer Coskun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1710843

2,212 views

Original Research

Published on 14 Oct 2025

MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway

in Diabetes: Molecular Mechanisms

Juan Zhang
Xiyin Zheng
Hong Zhang
Juan Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1669791

1,783 views

Review

Published on 13 Oct 2025

GLP-1 receptor agonists synergistic effects of metabolic reprogramming and cardioprotection

in Diabetes: Molecular Mechanisms

Xuan Wang
Mengmeng Qi
Lili Yang
Libo Yang
Xiaoyue Wang
Fang Zhang
Yukun Cui
Dongxin Wang
Yangang Wang
Wenshan Lv

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1614726

2,501 views
1 citation

Systematic Review

Published on 13 Oct 2025

The rs7799039 variant in the leptin gene promoter drives insulin resistance through reduced serum leptin levels

in Diabetes: Molecular Mechanisms

Yongyan Song
Youjin Zhang
Xinyu Liu
Wang Gong
Yinquan Ai
Binger Shen
Jing Li
Chuan He

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1589575

2,094 views
1 citation

Review

Published on 13 Oct 2025

Treatment of T2DM-related inflammation and vascular injury by regulating cellular crosstalk in the islet microenvironment

in Diabetes: Molecular Mechanisms

Aru Sun
Haoyu Yang
Jun Sun
Jinli Luo
Ling Zhou
Tingting Bao
Xiaolin Tong
Yiqun Lin
Lin Han

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1551853

2,286 views

853 articles

articles

Correction: Single-cell profiling reveals transcriptomic signatures of vascular endothelial cells in non-healing diabetic foot ulcers

Editorial: In vivo magnetic resonance imaging of metabolic disorders

Multi level effects of Sanghuang Tongxie Formula on type 2 diabetes rats: a comprehensive analysis from intestinal bacteria to metabolome and transcriptome

Genetic Landscape of Neonatal Diabetes Mellitus (NDM) in the Middle East, North Africa, and Türkiye (MENAT): A Systematic Review

Sodium-glucose cotransporter 2 inhibitors—but not insulin—enhance renal branched-chain amino acid catabolism

MicroRNAs modulated by DPP-4 inhibitor and bedtime NPH insulin therapy in individuals with type 2 diabetes

Diabetic kidney disease macrophage cholesterol efflux: a revolution from metabolism to immune

The role of dysregulated copper metabolism in diabetes and its complications: a review

Association of TNF-α polymorphisms rs1800629 (−308G>A) and rs361525 (−238G>A) with type 2 diabetes mellitus in the Punjabi population of Pakistan

Comprehensive transcriptomic profiling reveals tissue-specific molecular signatures and dysregulated pathways in human diabetic foot ulcers

U-TXM: a novel biomarker for early detection of diabetic kidney disease

Deciphering the epigenetic role of KDM4A in pancreatic β-like cell differentiation from iPSCs

Genetic/epigenetic RNA dysregulation in type 2 diabetes mellitus complicated with ischemic heart disease

Yerba Maté and its impact on glycemic control and metabolic health: a systematic review and meta-analysis

Identification and validation of key mitophagy-related biomarkers in the pathogenesis of proliferative diabetic retinopathy

Allyl nonanoate as a novel bile-derived biomarker in metabolic dysfunction-associated steatotic liver disease

MODY PDX1P33T: a mouse model reveals phenotypic divergence from human disease

Growth factor and hypoxia-inducible factor alpha content in the retina of male Wistar rats in experimental diabetic retinopathy and the effect of cellular protein kinase blockade

BRI is an independent predictor of new-onset kidney stones in a non-diabetic population: a retrospective analysis

Editorial: The impact of GIP/GIPR on metabolic diseases: how the field is evolving

MiR-216a-5p protects against high glucose-induced HMC injury by targeting the HMGB1/RAGE signaling pathway

GLP-1 receptor agonists synergistic effects of metabolic reprogramming and cardioprotection

The rs7799039 variant in the leptin gene promoter drives insulin resistance through reduced serum leptin levels

Treatment of T2DM-related inflammation and vascular injury by regulating cellular crosstalk in the islet microenvironment