Frontiers in Endocrinology | Diabetes: Molecular Mechanisms

Review

Published on 30 Jun 2025

Targeting gut microbiota for diabetic nephropathy treatment: probiotics, dietary interventions, and fecal microbiota transplantation

in Diabetes: Molecular Mechanisms

Xiaoran Wang
Xinyin Liu
Fanghong Gong
Yan Jiang
Canwei Zhang
Wei Zhou
Wen Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1621968

5,045 views
4 citations

Original Research

Published on 25 Jun 2025

A murine model of gestational diabetes reveals MASLD risk and alterations in markers of hepatic mitochondrial metabolism

in Diabetes: Molecular Mechanisms

Grace E. Shryack
Alexa A. Krause
Simone Hernandez Ruano
Laura C. Schulz
Kathleen A. Pennington
R. Scott Rector

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1498764

3,618 views
1 citation

Original Research

Published on 20 Jun 2025

Integrated transcriptomic, proteomic, and metabolomic analysis unveils key roles of protein and nucleic acid interactions in diabetic ulcer pathogenesis

in Diabetes: Molecular Mechanisms

Yongpan Lu
Hairui Gao
Sen Wang
Han Xu
Zhiyu Chen
Yixin Zhang
Yunfei Gu
Xiaomei Sun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1574858

3,189 views
3 citations

Mini Review

Published on 19 Jun 2025

Harnessing beta-cell replication: advancing molecular insights to regenerative therapies in diabetes

in Diabetes: Molecular Mechanisms

Rupangi C. Vasavada
Sangeeta Dhawan

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1612576

3,231 views

Editorial

Published on 18 Jun 2025

Editorial: Dietary and nutrigenetic contributors to metabolic syndrome

in Diabetes: Molecular Mechanisms

Anoop Arunagiri
Maroof Alam
Erez Dror
Melkam A. Kebede

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1632753

1,405 views
1 citation

Original Research

Published on 17 Jun 2025

Metabolic adaptation to acute metabolic stress via PFKFB3 upregulation in rodent beta cells

in Diabetes: Molecular Mechanisms

Koki Chiba
Hiroshi Nomoto
Rimi Izumihara
Xinxin Zhang
Hiraku Kameda
Akinobu Nakamura
Tatsuya Atsumi

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1552700

2,589 views

Original Research

Published on 17 Jun 2025

Assessment of reconstruction accuracy for under-sampled 31P-MRS data using compressed sensing and a low rank Hankel matrix completion approach

in Diabetes: Molecular Mechanisms

Jossian A. García
Michael D. Noseworthy
Alejandro Santos-Díaz

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1581328

1,479 views

Review

Published on 11 Jun 2025

Targeting programmed cell death pathways: emerging therapeutic strategies for diabetic kidney disease

in Diabetes: Molecular Mechanisms

Lin Wang
Shaowei Ding
Yuxin Hu
Jiaming Su
Gegongming Zhu
Hanzhang Hong
Baoluo Hou
Zhaoxi Dong
Zeyu Xue
Jiayi Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1513895

5,737 views
2 citations

Perspective

Published on 29 May 2025

Reframing type 1 diabetes through the endocannabinoidome-microbiota axis: a systems biology perspective

in Diabetes: Molecular Mechanisms

Wojciech Łukowski

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1576419

5,653 views
2 citations

Original Research

Published on 23 May 2025

Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway

in Diabetes: Molecular Mechanisms

Yanyu Pang
Lei Tian
Yufei Liu
Yifan Guo
Jingwen Zhao
Yutong Wang
Mengdi Wang
Wenjing Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1606326

4,678 views

Mini Review

Published on 21 May 2025

Research progress on Nrf2 intervention in the treatment of diabetic retinopathy

in Diabetes: Molecular Mechanisms

Yuchen Yang
Haidong Zou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1587231

3,702 views
1 citation

Review

Published on 21 May 2025

The evolution of the therapeutic concept ‘GIP receptor antagonism’

in Diabetes: Molecular Mechanisms

Frederikke Koefoed-Hansen
Mads Marstrand Helsted
Hüsün Sheyma Kizilkaya
Asger Bach Lund
Mette Marie Rosenkilde
Lærke Smidt Gasbjerg

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1570603

6,345 views
2 citations

Review

Published on 21 May 2025

Immune cell contribution to vascular complications in diabetes

in Diabetes: Molecular Mechanisms

Lingli Ma
Xuejiao Zhang
Zimeng Li
Qing Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1549945

2,976 views
6 citations

Original Research

Published on 21 May 2025

MAPK8 and HDAC6: potential biomarkers related to autophagy in diabetic retinopathy based on bioinformatics analysis

in Diabetes: Molecular Mechanisms

Ruotong Sun
Ling Zuo

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1487007

3,163 views

Systematic Review

Published on 21 May 2025

Gut-associated metabolites and diabetes pathology: a systematic review

in Diabetes: Molecular Mechanisms

Katelyn L. Gough
Samantha J. Dando
Stephanie L. Teasdale
Beatrix Feigl
Flavia Huygens
Elise S. Pelzer

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1559638

4,135 views

Original Research

Published on 19 May 2025

Molecular and clinical profiles of T2DM, dyslipidemia, and periodontitis: insights into inflammatory and metabolic dysregulation

in Diabetes: Molecular Mechanisms

Peace Ngozi Okoro
George Oche Ambrose
Victor Emmanuel Obaro
Chidiebere Valentine Ugwueze
J. K. Olarinoye
Olalekan A. Agede

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1574392

2,531 views
2 citations

Review

Published on 16 May 2025

Influence of gestational diabetes mellitus on the cardiovascular system and its underlying mechanisms

in Diabetes: Molecular Mechanisms

Ze Zhang
Yumeng Zhang
Shuai Huang
Min Li
Lingjun Li
Linglu Qi
Yun He
Zhice Xu
Jiaqi Tang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1474643

4,042 views
2 citations

Mini Review

Published on 15 May 2025

Recent advances in early diagnosis and treatment of T1D with miRNAs

in Diabetes: Molecular Mechanisms

Xinling Zhang
Yuting Qiu
Dong-ang Liu
Ruiyao Hu
Shiyu Chen
Yue Xu
Keyi Chen
Jinghua Yuan
Xiaoping Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1582963

2,525 views
2 citations

Review

Published on 14 May 2025

Trained immunity in diabetes: emerging targets for cardiovascular complications

in Diabetes: Molecular Mechanisms

Yanan Bai
Jianglan Wu
Weixiong Jian

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1533620

3,992 views
2 citations

Original Research

Published on 13 May 2025

Maternal diabetes disrupts early corticogenesis through altered mitotic gene regulation: a transcriptomic analysis

in Diabetes: Molecular Mechanisms

Rocío Valle-Bautista
Diana S. de la Merced-García
Dafne A. Díaz-Piña
Néstor Fabián Díaz
Daniela Ávila-González
Anayansi Molina-Hernández

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1564441

2,912 views

Review

Published on 12 May 2025

Diabetes and brain: omics approaches to study diabetic encephalopathy

in Diabetes: Molecular Mechanisms

Nicoletta Lionetti
Maria Grazia Di Lago
Tania Brescia
Federica Bevilacqua
Antonio Gnoni

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1570585

3,974 views
1 citation

Perspective

Published on 09 May 2025

Associated factors and principal pathophysiological mechanisms of type 2 diabetes mellitus

in Diabetes: Molecular Mechanisms

Luyao Wang
Lianxin Li
Jiaxin Liu
Changting Sheng
Maoyi Yang
Zhipeng Hu
Rensong Yue

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1499565

8,204 views
6 citations

Systematic Review

Published on 05 May 2025

Comparing the impacts of different exercise interventions on patients with type 2 diabetes mellitus: a literature review and meta-analysis

in Diabetes: Molecular Mechanisms

Shuangtao Xing
Yifan Zhang
Yanjiao Chen
Shijie Feng
Yiqing Zhang
Paulo Moreira

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1495131

11,916 views
4 citations

Mini Review

Published on 17 Apr 2025

Role of lactoferrin and its derived peptides in metabolic syndrome treatment

in Diabetes: Molecular Mechanisms

Xicui Zong
Yajing Wang
Yuqing Chen
Penghua Fang
Yi Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1562653

4,233 views
1 citation

833 articles

articles

Targeting gut microbiota for diabetic nephropathy treatment: probiotics, dietary interventions, and fecal microbiota transplantation

A murine model of gestational diabetes reveals MASLD risk and alterations in markers of hepatic mitochondrial metabolism

Integrated transcriptomic, proteomic, and metabolomic analysis unveils key roles of protein and nucleic acid interactions in diabetic ulcer pathogenesis

Harnessing beta-cell replication: advancing molecular insights to regenerative therapies in diabetes

Editorial: Dietary and nutrigenetic contributors to metabolic syndrome

Metabolic adaptation to acute metabolic stress via PFKFB3 upregulation in rodent beta cells

Assessment of reconstruction accuracy for under-sampled 31P-MRS data using compressed sensing and a low rank Hankel matrix completion approach

Targeting programmed cell death pathways: emerging therapeutic strategies for diabetic kidney disease

Reframing type 1 diabetes through the endocannabinoidome-microbiota axis: a systems biology perspective

Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway

Research progress on Nrf2 intervention in the treatment of diabetic retinopathy

The evolution of the therapeutic concept ‘GIP receptor antagonism’

Immune cell contribution to vascular complications in diabetes

MAPK8 and HDAC6: potential biomarkers related to autophagy in diabetic retinopathy based on bioinformatics analysis

Gut-associated metabolites and diabetes pathology: a systematic review

Molecular and clinical profiles of T2DM, dyslipidemia, and periodontitis: insights into inflammatory and metabolic dysregulation

Influence of gestational diabetes mellitus on the cardiovascular system and its underlying mechanisms

Recent advances in early diagnosis and treatment of T1D with miRNAs

Trained immunity in diabetes: emerging targets for cardiovascular complications

Maternal diabetes disrupts early corticogenesis through altered mitotic gene regulation: a transcriptomic analysis

Diabetes and brain: omics approaches to study diabetic encephalopathy

Associated factors and principal pathophysiological mechanisms of type 2 diabetes mellitus

Comparing the impacts of different exercise interventions on patients with type 2 diabetes mellitus: a literature review and meta-analysis

Role of lactoferrin and its derived peptides in metabolic syndrome treatment