Frontiers in Endocrinology | Diabetes: Molecular Mechanisms

Original Research

Published on 11 Aug 2025

Association of hemoglobin-to-red cell distribution width ratio with diabetic retinopathy risk and severity

in Diabetes: Molecular Mechanisms

Bin Wang
Hui Li
Lin Wang
Zaihong Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1622460

2,843 views

Original Research

Published on 11 Aug 2025

Immunological profiling in type 2 diabetes mellitus and type 2 diabetic kidney disease: insights from single-cell LacNAc sequencing

in Diabetes: Molecular Mechanisms

Mengyun Xiao
Zigan Xu
Xiaohui Zhu
Jing Chen
Ru Wang
Yaxuan Wang
Xiang Gao
Shaodong Luan
Xiaoyan Pu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1550925

2,790 views
1 citation

Original Research

Published on 07 Aug 2025

LC-MS-based conventional metabolomics combined with machine learning models to identify metabolic markers for the diagnosis of type I diabetes

in Diabetes: Molecular Mechanisms

Muhadasi Tuerxunyiming
Qing Zhao
Qiaosheng Hu
Ping Zhu
Shiting Zhu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1588718

2,565 views
1 citation

Systematic Review

Published on 06 Aug 2025

Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis

in Diabetes: Molecular Mechanisms

Li Cui
Donglei Lu
Sijie Tan
Liquan Cao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1462104

6,556 views

Original Research

Published on 01 Aug 2025

Effect of Imeglimin on mitochondrial function in patients with type 2 diabetes mellitus: a prospective cohort study

in Diabetes: Molecular Mechanisms

Abhishek Satheesan
Janardanan Kumar
Kakithakara Vajravelu Leela
Ria Murugesan

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1585834

3,147 views
1 citation

Review

Published on 31 Jul 2025

Notch signaling in diabetic kidney disease: recent progress

in Diabetes: Molecular Mechanisms

Zhi-Hui Wang
Wei Tu
Ya-Ni Long
Peng-Fei Li
Kai-Ying He
Jing Wu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1537769

4,184 views
1 citation

Original Research

Published on 30 Jul 2025

Network pharmacological investigation and experimental verification of the peel of Zea mays L. regulating metabolic reprogramming in the treatment of diabetic nephropathy

in Diabetes: Molecular Mechanisms

Andong Wang
Yuru Yang
Yaonan He
Guangtong Chen
Bai Ling
Xiaotian Cheng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1594782

3,149 views

Review

Published on 29 Jul 2025

Research progress on non-coding RNA regulatory networks and targeted therapy in diabetic nephropathy

in Diabetes: Molecular Mechanisms

Xiaxia Wang
Ruge Jing
Tong Yang
Ruiwen Shao
Fan Yang
Yangyang Shi
Xiujuan Yang
Dong An
Yonglin Liang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1625307

3,957 views
1 citation

Perspective

Published on 28 Jul 2025

Predictors of powerhouse: a perspective of mitochondrial biomarkers in type 2 diabetes

in Diabetes: Molecular Mechanisms

Mónica Muñoz-Úbeda
Surjya Narayan Dash

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1595557

2,939 views
1 citation

Original Research

Published on 23 Jul 2025

Genetic variants in HLA-DQA1/DQB1 genes modulate the risk of gestational diabetes mellitus in a southern Chinese population

in Diabetes: Molecular Mechanisms

Lijie Nie
Yan Sun
Ruiqi Li
Qiulian Liang
Guocun Deng
Xinyu He
Yifei Zeng
Hui Zheng
Xinhe Xiao
Xiaodong Ding

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1511561

1,829 views

Mini Review

Published on 18 Jul 2025

Advances in in vivo magnetic resonance spectroscopy for metabolic disorders

in Diabetes: Molecular Mechanisms

Yuliya Kupriyanova
Vera Schrauwen-Hinderling

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1578333

2,978 views

Original Research

Published on 18 Jul 2025

Shared diagnostic genes and potential mechanisms between intervertebral disc degeneration and diabetes mellitus revealed by integrated transcriptomic analysis and machine learning

in Diabetes: Molecular Mechanisms

Bao Song
Jianmin Wang
Hao Tang
Huadong Li
Wanli Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1576826

1,976 views
1 citation

Editorial

Published on 18 Jul 2025

Editorial: Deciphering the immunological and neuronal regulators of diabesity

in Diabetes: Molecular Mechanisms

Chandan Sona
Rakesh B. Patel
Surendra Ugale
Dinesh Kumar Verma

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1657868

1,275 views

Review

Published on 17 Jul 2025

Mechanisms and therapeutics of insulin signaling transduction genes in diabetic cardiomyopathy: a comprehensive updated review

in Diabetes: Molecular Mechanisms

Yufeng He
Xi Yang
Xinghui He
Guoshuang Wang
Chuang Li
Ping Yuan
Chunhong Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1589695

4,106 views
2 citations

Editorial

Published on 11 Jul 2025

Editorial: Diabetic wound: multifaceted mechanisms and future of diabetic wound healing, volume II

in Diabetes: Molecular Mechanisms

Shiying Shao
Johnson Boey
Xingwu Ran

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1650648

2,026 views

Systematic Review

Published on 09 Jul 2025

Data mining–based analysis to explore the application of an animal model of diabetic gastroparesis

in Diabetes: Molecular Mechanisms

Hui Xu
Fu-rui Miao
Yu-jun He
Yu-shan Fan

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1612473

3,463 views

Review

Published on 08 Jul 2025

Immune inflammation and metabolic interactions in the pathogenesis of diabetic nephropathy

in Diabetes: Molecular Mechanisms

Guangjian Hou
Youzi Dong
Yuehua Jiang
Wenbo Zhao
Le Zhou
Shengnan Cao
Wei Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1602594

8,086 views
19 citations

Mini Review

Published on 07 Jul 2025

Targeting advanced glycation end products: potential therapeutic approaches for mitigating diabetic intervertebral disc degeneration?

in Diabetes: Molecular Mechanisms

Luyang Wang
Qipeng Shao
Haiyang Wu
Cheng Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1618984

3,345 views

Original Research

Published on 02 Jul 2025

Interleukin-4 prevents increased endothelial permeability by inducing pericyte survival and modulating microglial responses in diabetic retinopathy

in Diabetes: Molecular Mechanisms

Jang-Hyuk Yun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1609796

2,771 views
1 citation

Review

Published on 02 Jul 2025

Evaluating the impact of lipids in isolated islet research

in Diabetes: Molecular Mechanisms

Emelien M. Jentz
Jamie W. Joseph

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1548596

2,075 views

Review

Published on 30 Jun 2025

Targeting gut microbiota for diabetic nephropathy treatment: probiotics, dietary interventions, and fecal microbiota transplantation

in Diabetes: Molecular Mechanisms

Xiaoran Wang
Xinyin Liu
Fanghong Gong
Yan Jiang
Canwei Zhang
Wei Zhou
Wen Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1621968

5,754 views
8 citations

Original Research

Published on 25 Jun 2025

A murine model of gestational diabetes reveals MASLD risk and alterations in markers of hepatic mitochondrial metabolism

in Diabetes: Molecular Mechanisms

Grace E. Shryack
Alexa A. Krause
Simone Hernandez Ruano
Laura C. Schulz
Kathleen A. Pennington
R. Scott Rector

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1498764

4,146 views
1 citation

Original Research

Published on 20 Jun 2025

Integrated transcriptomic, proteomic, and metabolomic analysis unveils key roles of protein and nucleic acid interactions in diabetic ulcer pathogenesis

in Diabetes: Molecular Mechanisms

Yongpan Lu
Hairui Gao
Sen Wang
Han Xu
Zhiyu Chen
Yixin Zhang
Yunfei Gu
Xiaomei Sun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1574858

3,609 views
4 citations

Mini Review

Published on 19 Jun 2025

Harnessing beta-cell replication: advancing molecular insights to regenerative therapies in diabetes

in Diabetes: Molecular Mechanisms

Rupangi C. Vasavada
Sangeeta Dhawan

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1612576

3,780 views
1 citation

853 articles

articles

Association of hemoglobin-to-red cell distribution width ratio with diabetic retinopathy risk and severity

Immunological profiling in type 2 diabetes mellitus and type 2 diabetic kidney disease: insights from single-cell LacNAc sequencing

LC-MS-based conventional metabolomics combined with machine learning models to identify metabolic markers for the diagnosis of type I diabetes

Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis

Effect of Imeglimin on mitochondrial function in patients with type 2 diabetes mellitus: a prospective cohort study

Notch signaling in diabetic kidney disease: recent progress

Network pharmacological investigation and experimental verification of the peel of Zea mays L. regulating metabolic reprogramming in the treatment of diabetic nephropathy

Research progress on non-coding RNA regulatory networks and targeted therapy in diabetic nephropathy

Predictors of powerhouse: a perspective of mitochondrial biomarkers in type 2 diabetes

Genetic variants in HLA-DQA1/DQB1 genes modulate the risk of gestational diabetes mellitus in a southern Chinese population

Advances in in vivo magnetic resonance spectroscopy for metabolic disorders

Shared diagnostic genes and potential mechanisms between intervertebral disc degeneration and diabetes mellitus revealed by integrated transcriptomic analysis and machine learning

Editorial: Deciphering the immunological and neuronal regulators of diabesity

Mechanisms and therapeutics of insulin signaling transduction genes in diabetic cardiomyopathy: a comprehensive updated review

Editorial: Diabetic wound: multifaceted mechanisms and future of diabetic wound healing, volume II

Data mining–based analysis to explore the application of an animal model of diabetic gastroparesis

Immune inflammation and metabolic interactions in the pathogenesis of diabetic nephropathy

Targeting advanced glycation end products: potential therapeutic approaches for mitigating diabetic intervertebral disc degeneration?

Interleukin-4 prevents increased endothelial permeability by inducing pericyte survival and modulating microglial responses in diabetic retinopathy

Evaluating the impact of lipids in isolated islet research

Targeting gut microbiota for diabetic nephropathy treatment: probiotics, dietary interventions, and fecal microbiota transplantation

A murine model of gestational diabetes reveals MASLD risk and alterations in markers of hepatic mitochondrial metabolism

Integrated transcriptomic, proteomic, and metabolomic analysis unveils key roles of protein and nucleic acid interactions in diabetic ulcer pathogenesis

Harnessing beta-cell replication: advancing molecular insights to regenerative therapies in diabetes