Frontiers in Endocrinology | Diabetes: Molecular Mechanisms

Original Research

Published on 20 Nov 2024

Exploring the pathogenesis, biomarkers, and potential drugs for type 2 diabetes mellitus and acute pancreatitis through a comprehensive bioinformatic analysis

in Diabetes: Molecular Mechanisms

Lei Zhong
Xi Yang
Yuxuan Shang
Yao Yang
Junchen Li
Shuo Liu
Yunshu Zhang
Jifeng Liu
Xingchi Jiang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1405726

4,329 views
5 citations

Original Research

Published on 18 Nov 2024

Identification of key genes and immune infiltration of diabetic peripheral neuropathy in mice and humans based on bioinformatics analysis

in Diabetes: Molecular Mechanisms

Yumin Zhang
Hui Zhou
Juan Liu
Nan Zhou

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1437979

3,943 views
3 citations

Review

Published on 15 Nov 2024

The potential mechanism of action of gut flora and bile acids through the TGR5/TRPV1 signaling pathway in diabetic peripheral neuropathic pain

in Diabetes: Molecular Mechanisms

Peng Chen
Xian Jiang
Jia Fu
Cehua Ou
Yao Li
Jing Jia
Changli Liao

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1419160

5,811 views
9 citations

Review

Published on 11 Nov 2024

Ferroptosis in diabetic cardiomyopathy: from its mechanisms to therapeutic strategies

in Diabetes: Molecular Mechanisms

Meimei Tian
Xinli Huang
Min Li
Pingping Lou
Huijie Ma
Xinli Jiang
Yaru Zhou
Yan Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1421838

9,591 views
11 citations

Original Research

Published on 07 Nov 2024

Glycemic profile variability as an independent predictor of diabetic retinopathy in patients with type 2 diabetes: a prospective cohort study

in Diabetes: Molecular Mechanisms

Fatemeh Dehghani Firouzabadi
Amirhossein Poopak
Sahar Samimi
Niloofar Deravi
Pooria Nakhaei
Ali Sheikhy
Fatemeh Moosaie
Soghra Rabizadeh
Alipasha Meysamie
Manouchehr Nakhjavani

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1383345

2,919 views
9 citations

Review

Published on 04 Nov 2024

New insights into the role of cellular senescence and chronic wounds

in Diabetes: Molecular Mechanisms

Huiqing Yang
Xin Zhang
Bo Xue

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1400462

6,195 views
17 citations

Original Research

Published on 31 Oct 2024

Identify novel therapeutic targets for type II diabetes and periodontitis: insights from single-cell analysis and Mendelian randomization analysis

in Diabetes: Molecular Mechanisms

Mingrui Zou
Jichun Yang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1410537

3,916 views

Original Research

Published on 31 Oct 2024

Comparative efficacy, toxicity, and insulin-suppressive effects of simvastatin and pravastatin in fatty acid-challenged mouse insulinoma MIN6 β-cell model

in Diabetes: Molecular Mechanisms

Hossein Arefanian
Sardar Sindhu
Fatema Al-Rashed
Fawaz Alzaid
Ashraf Al Madhoun
Mohammed Qaddoumi
Fatemah Bahman
Michayla R. Williams
Shaima Albeloushi
Nourah Almansour

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1383448

3,772 views

Original Research

Published on 30 Oct 2024

Exploring diabesity pathophysiology through proteomic analysis using Caenorhabditis elegans

in Diabetes: Molecular Mechanisms

Malaimegu Subhadra
Dilawar Ahmad Mir
Koley Ankita
Muthukrishnan Sindunathy
Hambram David Kishore
Velayutham Ravichandiran
Krishnaswamy Balamurugan

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1383520

4,830 views
3 citations

Original Research

Published on 28 Oct 2024

A cross-sectional study in adiponectin, glucose metabolism, and body composition in cystic fibrosis

in Diabetes: Molecular Mechanisms

Bibi Uhre Nielsen
Christine Råberg Mikkelsen
Peter Sandor Oturai
Rikke Krogh-Madsen
Terese Lea Katzenstein
Christian Ritz
Tacjana Pressler
Thomas Peter Almdal
Inger Hee Mabuza Mathiesen
Daniel Faurholt-Jepsen

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1382241

1,824 views

Original Research

Published on 28 Oct 2024

A genome-wide association study identifies genetic determinants of hemoglobin glycation index with implications across sex and ethnicity

in Diabetes: Molecular Mechanisms

John S. House
Joseph H. Breeyear
Farida S. Akhtari
Violet Evans
John B. Buse
James Hempe
Alessandro Doria
Josyf C. Mychaleckyi
Vivian Fonseca
Mengyao Shi

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1473329

3,728 views

Original Research

Published on 21 Oct 2024

Pancreatic β-cells package double C2-like domain beta protein into extracellular vesicles via tandem C2 domains

in Diabetes: Molecular Mechanisms

Diana Esparza
Carinna Lima
Sarah Abuelreich
Ima Ghaeli
Jinhee Hwang
Eunjin Oh
Ayelet Lenz
Angel Gu
Nan Jiang
Fouad Kandeel

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1451279

7,507 views
1 citation

Original Research

Published on 14 Oct 2024

Tracing links between micronutrients and type 2 diabetes risk: the singular role of selenium

in Diabetes: Molecular Mechanisms

Wenxing Zeng
Shan Jiang
Dejun Cun
Feng Huang
Ziwei Jiang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1422796

3,121 views
6 citations

Review

Published on 08 Oct 2024

The emerging modulators of non-coding RNAs in diabetic wound healing

in Diabetes: Molecular Mechanisms

Sis Aghayants
Jinjin Zhu
Jing Yu
Rui Tao
Sicheng Li
Shengzhi Zhou
Yunhua Zhou
Zhanyong Zhu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1465975

5,081 views
6 citations

Mini Review

Published on 25 Sep 2024

Modelling human diabetes ex vivo: a glance at maturity onset diabetes of the young

in Diabetes: Molecular Mechanisms

Moustapha Ka
Eleanor Hawkins
Celio Pouponnot
Bertrand Duvillié

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1427413

3,067 views

Original Research

Published on 23 Sep 2024

Adipose tissue insulin resistance in young Japanese women is associated with metabolic abnormalities and dehydroepiandrosterone-sulfate

in Diabetes: Molecular Mechanisms

Motonori Sato
Yoshifumi Tamura
Hideyoshi Kaga
Nozomu Yamasaki
Satoshi Kadowaki
Daisuke Sugimoto
Takashi Nakagata
Yuki Someya
Yuya Nishida
Ryuzo Kawamori

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1390778

2,323 views
3 citations

Review

Published on 20 Sep 2024

Exploring the design of clinical research studies on the efficacy mechanisms in type 2 diabetes mellitus

in Diabetes: Molecular Mechanisms

Huifang Guan
Shuang Zhao
Jiarui Li
Ying Wang
Ping Niu
Yuxin Zhang
Yanjiao Zhang
Xinyi Fang
Runyu Miao
Jiaxing Tian

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1363877

4,616 views
7 citations

Original Research

Published on 18 Sep 2024

Longitudinal associations between microRNAs and weight in the diabetes prevention program

in Diabetes: Molecular Mechanisms

Elena Flowers
Benjamin Stroebel
Xingyue Gong
Kimberly A. Lewis
Bradley E. Aouizerat
Meghana Gadgil
Alka M. Kanaya
Li Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1419812

3,228 views
3 citations

Perspective

Published on 17 Sep 2024

MG53’s non-physiologic interaction with insulin receptor: lack of effect on insulin-stimulated Akt phosphorylation in muscle, heart and liver tissues

in Diabetes: Molecular Mechanisms

Kyung Eun Lee
Miyuki Nishi
Jongsoo Kim
Takashi Murayama
Zachary Dawson
Xiaoliang Wang
Xinyu Zhou
Tao Tan
Chuanxi Cai
Hiroshi Takeshima

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1425426

2,520 views

Original Research

Published on 13 Sep 2024

Causal role of immune cells in diabetic nephropathy: a bidirectional Mendelian randomization study

in Diabetes: Molecular Mechanisms

Shang-Yuan Wang
Yang Yu
Xiao-Li Ge
Shuming Pan

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1357642

2,889 views
3 citations

Original Research

Published on 06 Sep 2024

Reduction of hyperglycemia in STZ-induced diabetic mice by prophylactic treatment with heat-killed Mycobacterium aurum: possible effects on glucose utilization, mitochondrial uncoupling, and oxidative stress in liver and skeletal muscle

in Diabetes: Molecular Mechanisms

Farid Abdallah
Samer Bazzi
Charles Akle
Georges M. Bahr
Karim S. Echtay

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1427058

4,141 views

Review

Published on 04 Sep 2024

N6-methyladenine RNA methylation epigenetic modification and diabetic microvascular complications

in Diabetes: Molecular Mechanisms

Yuanyuan Wang
Jiayun Zou
Hua Zhou

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1462146

3,042 views
3 citations

Review

Published on 03 Sep 2024

Exploring molecular mechanisms of exercise on metabolic syndrome: a bibliometric and visualization study using CiteSpace

in Diabetes: Molecular Mechanisms

Kang Wan
Yue Jin
Ruobing Fan
Qizi Xu
Xiaoshi Li
Hongmei Yan
Ru Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1408466

6,833 views
3 citations

Original Research

Published on 30 Aug 2024

Mitochondrial dysfunction and onset of type 2 diabetes along with its complications: a multi-omics Mendelian randomization and colocalization study

in Diabetes: Molecular Mechanisms

Yang Li
Yahu Miao
Qing Feng
Weixi Zhu
Yijing Chen
Qingqing Kang
Zhen Wang
Fangting Lu
Qiu Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1401531

9,332 views
7 citations

835 articles

articles

Exploring the pathogenesis, biomarkers, and potential drugs for type 2 diabetes mellitus and acute pancreatitis through a comprehensive bioinformatic analysis

Identification of key genes and immune infiltration of diabetic peripheral neuropathy in mice and humans based on bioinformatics analysis

The potential mechanism of action of gut flora and bile acids through the TGR5/TRPV1 signaling pathway in diabetic peripheral neuropathic pain

Ferroptosis in diabetic cardiomyopathy: from its mechanisms to therapeutic strategies

Glycemic profile variability as an independent predictor of diabetic retinopathy in patients with type 2 diabetes: a prospective cohort study

New insights into the role of cellular senescence and chronic wounds

Identify novel therapeutic targets for type II diabetes and periodontitis: insights from single-cell analysis and Mendelian randomization analysis

Comparative efficacy, toxicity, and insulin-suppressive effects of simvastatin and pravastatin in fatty acid-challenged mouse insulinoma MIN6 β-cell model

Exploring diabesity pathophysiology through proteomic analysis using Caenorhabditis elegans

A cross-sectional study in adiponectin, glucose metabolism, and body composition in cystic fibrosis

A genome-wide association study identifies genetic determinants of hemoglobin glycation index with implications across sex and ethnicity

Pancreatic β-cells package double C2-like domain beta protein into extracellular vesicles via tandem C2 domains

Tracing links between micronutrients and type 2 diabetes risk: the singular role of selenium

The emerging modulators of non-coding RNAs in diabetic wound healing

Modelling human diabetes ex vivo: a glance at maturity onset diabetes of the young

Adipose tissue insulin resistance in young Japanese women is associated with metabolic abnormalities and dehydroepiandrosterone-sulfate

Exploring the design of clinical research studies on the efficacy mechanisms in type 2 diabetes mellitus

Longitudinal associations between microRNAs and weight in the diabetes prevention program

MG53’s non-physiologic interaction with insulin receptor: lack of effect on insulin-stimulated Akt phosphorylation in muscle, heart and liver tissues

Causal role of immune cells in diabetic nephropathy: a bidirectional Mendelian randomization study

Reduction of hyperglycemia in STZ-induced diabetic mice by prophylactic treatment with heat-killed Mycobacterium aurum: possible effects on glucose utilization, mitochondrial uncoupling, and oxidative stress in liver and skeletal muscle

N6-methyladenine RNA methylation epigenetic modification and diabetic microvascular complications

Exploring molecular mechanisms of exercise on metabolic syndrome: a bibliometric and visualization study using CiteSpace

Mitochondrial dysfunction and onset of type 2 diabetes along with its complications: a multi-omics Mendelian randomization and colocalization study