Frontiers in Endocrinology | Molecular and Structural Endocrinology

Mini Review

Published on 04 May 2018

Therapeutic Interference With Vascular Calcification—Lessons From Klotho-Hypomorphic Mice and Beyond

in Molecular and Structural Endocrinology

Florian Lang
Christina Leibrock
Lisann Pelzl
Meinrad Gawaz
Burkert Pieske
Ioana Alesutan
Jakob Voelkl

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00207

7,743 views
31 citations

Review

Published on 02 May 2018

FGF23 Actions on Target Tissues—With and Without Klotho

in Molecular and Structural Endocrinology

Beatrice Richter
Christian Faul

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00189

41,143 views
179 citations

Original Research

Published on 25 Apr 2018

Identification and Functional Characterization of a Novel Mutation in the Human Calcium-Sensing Receptor That Co-Segregates With Autosomal-Dominant Hypocalcemia

in Molecular and Structural Endocrinology

Anne Qvist Rasmussen
Niklas Rye Jørgensen
Peter Schwarz

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00200

4,224 views
10 citations

Review

Published on 17 Apr 2018

ANGPTL8: An Important Regulator in Metabolic Disorders

in Molecular and Structural Endocrinology

Mengdie Luo
Daoquan Peng

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00169

12,711 views
72 citations

Original Research

Published on 22 Mar 2018

Nuclear Insulin-Like Growth Factor Binding Protein-3 As a Biomarker in Triple-Negative Breast Cancer Xenograft Tumors: Effect of Targeted Therapy and Comparison With Chemotherapy

in Molecular and Structural Endocrinology

Sohel M. Julovi
Janet L. Martin
Robert C. Baxter

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00120

5,436 views
23 citations

Review

Published on 13 Mar 2018

An Approach to Greater Specificity for Glucocorticoids

in Molecular and Structural Endocrinology

Carson C. Chow
S. Stoney Simons

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00076

3,569 views
10 citations

Review

Published on 20 Feb 2018

Targeting Fibroblast Growth Factor 23 Signaling with Antibodies and Inhibitors, Is There a Rationale?

in Molecular and Structural Endocrinology

Seiji Fukumoto

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00048

10,380 views
27 citations

Original Research

Published on 20 Feb 2018

Molecular Modeling of Structures and Interaction of Human Corticotropin-Releasing Factor (CRF) Binding Protein and CRF Type-2 Receptor

in Molecular and Structural Endocrinology

Paula G. Slater
Sebastian E. Gutierrez-Maldonado
Katia Gysling
Carlos F. Lagos

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00043

6,355 views
6 citations

Review

Published on 20 Feb 2018

IGF Binding Protein-5 Induces Cell Senescence

in Molecular and Structural Endocrinology

Fumihiro Sanada
Yoshiaki Taniyama
Jun Muratsu
Rei Otsu
Hideo Shimizu
Hiromi Rakugi
Ryuichi Morishita

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00053

10,603 views
64 citations

Review

Published on 16 Feb 2018

Insulin- like Growth Factor-Binding Protein Action in Bone Tissue: A Key Role for Pregnancy- Associated Plasma Protein-A

in Molecular and Structural Endocrinology

James Beattie
Hasanain Al-Khafaji
Pernille R. Noer
Hanaa Esa Alkharobi
Aishah Alhodhodi
Josephine Meade
Reem El-Gendy
Claus Oxvig

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00031

7,675 views
24 citations

Review

Published on 13 Feb 2018

The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects

in Molecular and Structural Endocrinology

Farhad Dehkhoda
Christine M. M. Lee
Johan Medina
Andrew J. Brooks

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00035

149,831 views
257 citations

Original Research

Published on 01 Feb 2018

Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties

in Molecular and Structural Endocrinology

Helder Veras Ribeiro Filho
Natália Bernardi Videira
Aline Villanova Bridi
Thais Helena Tittanegro
Fernanda Aparecida Helena Batista
José Geraldo de Carvalho Pereira
Paulo Sérgio Lopes de Oliveira
Marcio Chaim Bajgelman
Albane Le Maire
Ana Carolina Migliorini Figueira

Frontiers in Endocrinology

doi 10.3389/fendo.2018.00011

15,851 views
24 citations

Mini Review

Published on 05 Jan 2018

Mechanistic Insights into Regulation of JAK2 Tyrosine Kinase

in Molecular and Structural Endocrinology

Stevan R. Hubbard

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00361

25,670 views
88 citations

Original Research

Published on 21 Dec 2017

Effect of Osteocyte-Ablation on Inorganic Phosphate Metabolism: Analysis of Bone–Kidney–Gut Axis

in Molecular and Structural Endocrinology

Osamu Fujii
Sawako Tatsumi
Mao Ogata
Tomohiro Arakaki
Haruna Sakaguchi
Kengo Nomura
Atsumi Miyagawa
Kayo Ikuta
Ai Hanazaki
Ichiro Kaneko

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00359

7,038 views
9 citations

Review

Published on 20 Nov 2017

Promoting Glucose Transporter-4 Vesicle Trafficking along Cytoskeletal Tracks: PAK-Ing Them Out

in Molecular and Structural Endocrinology

Ragadeepthi Tunduguru
Debbie C. Thurmond

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00329

22,941 views
37 citations

Review

Published on 20 Nov 2017

Cytokines in Male Fertility and Reproductive Pathologies: Immunoregulation and Beyond

in Molecular and Structural Endocrinology

Kate L. Loveland
Britta Klein
Dana Pueschl
Sivanjah Indumathy
Martin Bergmann
Bruce E. Loveland
Mark P. Hedger
Hans-Christian Schuppe

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00307

24,437 views
189 citations

Review

Published on 17 Nov 2017

New Insights into the Mechanism of Action of Soluble Klotho

in Molecular and Structural Endocrinology

George D. Dalton
Jian Xie
Sung-Wan An
Chou-Long Huang

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00323

30,316 views
194 citations

Original Research

Published on 26 Sep 2017

Levels of Hepatic Activating Transcription Factor 6 and Caspase-3 Are Downregulated in Mice after Excessive Training

in Molecular and Structural Endocrinology

Ana P. Pinto
Alisson L. da Rocha
Luciana da C. Oliveira
Gustavo P. Morais
Larissa G. de Vicente
Dennys E. Cintra
José R. Pauli
Leandro P. Moura
Eduardo R. Ropelle
Adelino S. R. da Silva

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00247

4,198 views
10 citations

Case Report

Published on 20 Sep 2017

Identification of MPL R102P Mutation in Hereditary Thrombocytosis

in Molecular and Structural Endocrinology

Christine Bellanné-Chantelot
Matthieu Mosca
Caroline Marty
Rémi Favier
William Vainchenker
Isabelle Plo

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00235

7,043 views
28 citations

Review

Published on 12 Sep 2017

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis

in Molecular and Structural Endocrinology

Isabelle Plo
Christine Bellanné-Chantelot
Matthieu Mosca
Stefania Mazzi
Caroline Marty
William Vainchenker

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00234

13,774 views
46 citations

Mini Review

Published on 16 Aug 2017

3-Iodothyronamine, a Novel Endogenous Modulator of Transient Receptor Potential Melastatin 8?

in Molecular and Structural Endocrinology

Noushafarin Khajavi
Stefan Mergler
Heike Biebermann

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00198

5,534 views
32 citations

Hypothesis and Theory

Published on 27 Jul 2017

Structural Perspectives of Insulin Receptor Isoform-Selective Insulin Analogs

in Molecular and Structural Endocrinology

Jiří Jiráček
Lenka Žáková

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00167

6,323 views
25 citations

Original Research

Published on 11 Jul 2017

Metabolic Characterization of a Novel RORα Knockout Mouse Model without Ataxia

in Molecular and Structural Endocrinology

Cyrielle Billon
Sadichha Sitaula
Thomas P. Burris

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00141

5,373 views
14 citations

Original Research

Published on 20 Jun 2017

Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor

in Molecular and Structural Endocrinology

Kareem Mohideen-Abdul
Karima Tazibt
Maxime Bourguet
Isabelle Hazemann
Isabelle Lebars
Maria Takacs
Sarah Cianférani
Bruno P. Klaholz
Dino Moras
Isabelle M. L. Billas

Frontiers in Endocrinology

doi 10.3389/fendo.2017.00140

6,588 views
16 citations

417 articles

articles

Therapeutic Interference With Vascular Calcification—Lessons From Klotho-Hypomorphic Mice and Beyond

FGF23 Actions on Target Tissues—With and Without Klotho

Identification and Functional Characterization of a Novel Mutation in the Human Calcium-Sensing Receptor That Co-Segregates With Autosomal-Dominant Hypocalcemia

ANGPTL8: An Important Regulator in Metabolic Disorders

Nuclear Insulin-Like Growth Factor Binding Protein-3 As a Biomarker in Triple-Negative Breast Cancer Xenograft Tumors: Effect of Targeted Therapy and Comparison With Chemotherapy

An Approach to Greater Specificity for Glucocorticoids

Targeting Fibroblast Growth Factor 23 Signaling with Antibodies and Inhibitors, Is There a Rationale?

Molecular Modeling of Structures and Interaction of Human Corticotropin-Releasing Factor (CRF) Binding Protein and CRF Type-2 Receptor

IGF Binding Protein-5 Induces Cell Senescence

Insulin- like Growth Factor-Binding Protein Action in Bone Tissue: A Key Role for Pregnancy- Associated Plasma Protein-A

The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects

Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties

Mechanistic Insights into Regulation of JAK2 Tyrosine Kinase

Effect of Osteocyte-Ablation on Inorganic Phosphate Metabolism: Analysis of Bone–Kidney–Gut Axis

Promoting Glucose Transporter-4 Vesicle Trafficking along Cytoskeletal Tracks: PAK-Ing Them Out

Cytokines in Male Fertility and Reproductive Pathologies: Immunoregulation and Beyond

New Insights into the Mechanism of Action of Soluble Klotho

Levels of Hepatic Activating Transcription Factor 6 and Caspase-3 Are Downregulated in Mice after Excessive Training

Identification of MPL R102P Mutation in Hereditary Thrombocytosis

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis

3-Iodothyronamine, a Novel Endogenous Modulator of Transient Receptor Potential Melastatin 8?

Structural Perspectives of Insulin Receptor Isoform-Selective Insulin Analogs

Metabolic Characterization of a Novel RORα Knockout Mouse Model without Ataxia

Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor