Frontiers in Endocrinology

Original Research

Published on 29 Oct 2025

Pdgfrα deficiency in islet β-cells up-regulates apoptosis of beta-cells and disturbs glucose metabolism in B6 mice

in Obesity

Luyao Zhang
Yanpeng Xing
Pai Wang
Jianlei Gu
Jian Peng
Juan Huang
James Alexander Pearson
Youjia Hu
Hongyu Zhao
F. Susan Wong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1630979

1,435 views

Original Research

Published on 29 Oct 2025

Increased spontaneous physical activity in female MEST-deficient mice protects against diet-induced obesity

in Obesity

Rea Victoria P. Anunciado-Koza
M. Elena Martinez
Victoria DeMambro
Arturo Hernandez
Robert A. Koza

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1680158

1,166 views

Original Research

Published on 21 Oct 2025

Obesity results in lower integrin expression in women with polycystic ovarian syndrome during the window of implantation

in Obesity

Fazilah Abdul Hamid
Mohd Helmy Mokhtar
Abdul Kadir Abdul Karim
Mohd Faizal Ahmad
Nor Haslinda Abd Aziz
Azantee Yazmie Abdul Wahab
Muhammad Azrai Abu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1590716

1,173 views

Review

Published on 17 Oct 2025

Metabolic impact of endogenously produced estrogens by adipose tissue in females and males across the lifespan

in Obesity

Angel A. Lee
Laura J. Den Hartigh

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1682231

2,925 views

Original Research

Published on 17 Oct 2025

Extreme gradient boosting using conventional parameters accurately predicts insulin sensitivity in young and middle-aged Japanese persons

in Obesity

Norimitsu Murai
Naoko Saito
Sayuri Nii
Hiroto Nishikawa
Eriko Kodama
Tatsuya Iida
Hideyuki Imai
Mai Hashizume
Rie Tadokoro
Chiho Sugisawa

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1661376

936 views

Review

Published on 14 Oct 2025

Analyzing and evaluating the metabolic and endocrine characteristics between lean and obese patients with polycystic ovary syndrome: a systemic review and meta-analysis

in Obesity

Caiyu Zheng
Yuhao Lin
Zhijun Zhang
Jiawen Ye
Yanmei Lin
Jianqing Tian

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1680685

2,469 views

Original Research

Published on 10 Oct 2025

Impact of the new EASO obesity definition on the detection of atheromatosis in subjects with low-to-moderate cardiovascular risk

in Obesity

Josep León-Mengíbar
Marcelino Bermúdez-López
José Manuel Valdivielso
Reinald Pamplona
Gerard Torres
Dídac Mauricio
Eva Castro-Boqué
Elvira Fernández
Assumpta Caixàs
Marta Bueno

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1689960

1,754 views

Original Research

Published on 10 Oct 2025

Temporal trends in cancer mortality attributable to high BMI in Asia: an age-period-cohort analysis based on GBD 1992–2021

in Obesity

Minguang Huang
Liejiong Wang
Ying Lou
Zhaoqi Qiu
Shengjian Yu
Feng Xuan

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1691487

1,674 views
1 citation

Original Research

Published on 10 Oct 2025

Obesity indices and their sociodemographic, lifestyle, and social isolation correlates in a large Spanish working population

in Obesity

Pere Riutord-Sbert
Pedro Juan Tárraga López
Ángel Arturo López-González
Irene Coll Campayo
Carla Busquets-Cortés
José Ignacio Ramírez Manent

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1695705

1,890 views

Review

Published on 09 Oct 2025

The role of exercise and nutrition in modulating inflammatory cytokines activity for obesity management

in Obesity

Sara Sobreviela Sánchez
Ravi Giusfredi Quevedo
Tiago Fernandes
Guilherme Wesley Peixoto da Fonseca

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1618360

2,770 views
1 citation

Original Research

Published on 08 Oct 2025

Transcriptomic elucidation of Dahuang-Huanglian in promoting white adipose browning in high-fat diet-induced obese rats

in Obesity

Ruiyao Zhang
Yu Zhang
Xi Xi
Pengcheng Du
Chao Guo
Yanying Zhang
Bing Song
Xiaoyan Xu
Zhitao Ni
Yongfeng Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1652703

2,034 views

Correction

Published on 02 Oct 2025

Correction: Pharmacotherapy for obesity: are we ready to select, tailor and combine pharmacotherapy to achieve more ambitious goals?

in Obesity

Nele Steenackers
Julia Toumassian
Ellen Deleus
Ann Mertens
Matthias Lannoo
Sofia Pazmino
Amar Daniël Emanuel van Laar
Bart Van der Schueren
Roman Vangoitsenhoven

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1656611

1,665 views

Original Research

Published on 01 Oct 2025

Obesity and cardiovascular risk factors among internists in Indonesia

in Obesity

Sally Aman Nasution
Lugyanti Sukrisman
Eka Ginanjar
Evy Yunihastuti
Simon Salim
Rudy Hidayat
Muhadi Muhadi
Siprianus Ugroseno Yudho Bintoro
Asri Ludin Tambunan
Hery Djagat Purnomo

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1594678

3,256 views

Systematic Review

Published on 26 Sep 2025

Association between weight-adjusted waist index and cardiovascular disease: a systematic review and meta-analysis

in Obesity

Kelly Pimenta
Edmore Madondo
Ayesha Mukhopadhyay
Jay Patel
Samuel Muhit
Fawaz Mzayek
Debra Bartelli
Matthew Smeltzer
Hongmei Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1644035

2,020 views

Original Research

Published on 25 Sep 2025

Obesity metabolomics signature in children: associations with metabolic abnormalities and potential biomarkers

in Obesity

Jiayi Wan
Shiyun Luo
Wanzhen Zhong
Guixian Tao
Jiaying Guo
Chunzi Zeng
Yujie Peng
Weiwei Zhang
Zhoubin Zhang
Jing Gu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1671613

1,808 views

Review

Published on 24 Sep 2025

White adipose tissue browning and peroxisome proliferator activated receptors in MASLD

in Obesity

Zexuan Li
Huikuan Chu
Ling Yang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1667037

2,985 views

Original Research

Published on 22 Sep 2025

Alterations in peripheral CD4+ T cell subsets and their association with metabolic markers in obese children

in Obesity

Reiko Saito
Jun Hirakawa
Mami Kuwamura
Takayuki Hoshina

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1635379

1,347 views

Review

Published on 17 Sep 2025

Bridging east and west: integrative approaches to obesity management through traditional Chinese medicine

in Obesity

Qianrong Li
Zhao Liu
Xiaolin Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1644381

3,904 views

Correction

Published on 16 Sep 2025

Correction: High-fat diet-induced dyslipidemia drives retinal ECE-1 and ET-1 upregulation

in Obesity

Shuo Sun
Huilan Zhang
Jing Chen
Kaiwen Hei
Yi Hou
Yanhui Yang
Chunyan Shan
Longli Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1699321

1,163 views

Original Research

Published on 16 Sep 2025

A leptin-based Bayesian inference of a pro-satiety state reflects a basal circadian rhythm in women with obesity

in Obesity

Qing Xiang
Saman Khazaei
Rose T. Faghih

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1638568

1,750 views

Original Research

Published on 15 Sep 2025

Regulators of RNA m5C methylation are adipose tissue depot-specific expressed and correlate with clinical variables of obesity in humans

in Obesity

Stina Ingrid Alice Svensson
Anne Hoffmann
Tobias Hagemann
Akin Cayir
Sadia Saeed
Adhideb Ghosh
Christian Wolfrum
Matthias Blüher
Yvonne Böttcher

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1647477

1,648 views

Review

Published on 11 Sep 2025

A glimpse into the pipeline of anti-obesity medication development: combining multiple receptor pathways

in Obesity

Christine Park
Yushin Kim
Sawye Raygani
Eduardo Grunvald

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1630199

5,064 views

Original Research

Published on 10 Sep 2025

Patterns of multimorbidity across obesity severity and fat distribution in Anhui, China: a community-based study

in Obesity

Keyi Gu
Weiqiang Wang
Weizhuo Yi
Handong Gu
Xiaoya Fu
Fei Yang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1652678

1,863 views
1 citation

Original Research

Published on 29 Aug 2025

High-fat diet-induced dyslipidemia drives retinal ECE-1 and ET-1 upregulation

in Obesity

Shuo Sun
Huilan Zhang
Jing Chen
Kaiwen Hei
Yi Hou
Yanhui Yang
Chunyan Shan
Longli Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1640890

1,487 views

1,160 articles

articles

Pdgfrα deficiency in islet β-cells up-regulates apoptosis of beta-cells and disturbs glucose metabolism in B6 mice

Increased spontaneous physical activity in female MEST-deficient mice protects against diet-induced obesity

Obesity results in lower integrin expression in women with polycystic ovarian syndrome during the window of implantation

Metabolic impact of endogenously produced estrogens by adipose tissue in females and males across the lifespan

Extreme gradient boosting using conventional parameters accurately predicts insulin sensitivity in young and middle-aged Japanese persons

Analyzing and evaluating the metabolic and endocrine characteristics between lean and obese patients with polycystic ovary syndrome: a systemic review and meta-analysis

Impact of the new EASO obesity definition on the detection of atheromatosis in subjects with low-to-moderate cardiovascular risk

Temporal trends in cancer mortality attributable to high BMI in Asia: an age-period-cohort analysis based on GBD 1992–2021

Obesity indices and their sociodemographic, lifestyle, and social isolation correlates in a large Spanish working population

The role of exercise and nutrition in modulating inflammatory cytokines activity for obesity management

Transcriptomic elucidation of Dahuang-Huanglian in promoting white adipose browning in high-fat diet-induced obese rats

Correction: Pharmacotherapy for obesity: are we ready to select, tailor and combine pharmacotherapy to achieve more ambitious goals?

Obesity and cardiovascular risk factors among internists in Indonesia

Association between weight-adjusted waist index and cardiovascular disease: a systematic review and meta-analysis

Obesity metabolomics signature in children: associations with metabolic abnormalities and potential biomarkers

White adipose tissue browning and peroxisome proliferator activated receptors in MASLD

Alterations in peripheral CD4+ T cell subsets and their association with metabolic markers in obese children

Bridging east and west: integrative approaches to obesity management through traditional Chinese medicine

Correction: High-fat diet-induced dyslipidemia drives retinal ECE-1 and ET-1 upregulation

A leptin-based Bayesian inference of a pro-satiety state reflects a basal circadian rhythm in women with obesity

Regulators of RNA m5C methylation are adipose tissue depot-specific expressed and correlate with clinical variables of obesity in humans

A glimpse into the pipeline of anti-obesity medication development: combining multiple receptor pathways

Patterns of multimorbidity across obesity severity and fat distribution in Anhui, China: a community-based study

High-fat diet-induced dyslipidemia drives retinal ECE-1 and ET-1 upregulation