Frontiers in Endocrinology | Systems Endocrinology

Original Research

Published on 20 Dec 2024

Association between the Fatty Liver Index (FLI) and incident coronary heart disease: insights from a cohort study on the Chinese population

in Systems Endocrinology

Ying Miao
Yu Wang
Pijun Yan
Yi Li
Zhuang Chen
Nanwei Tong
Qin Wan

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1367853

2,651 views
4 citations

Original Research

Published on 17 Dec 2024

Circulating irisin levels in patients with MAFLD: an updated systematic review and meta-analysis

in Systems Endocrinology

Chenglu Shen
Kaihan Wu
Yani Ke
Qin Zhang
Shuaihang Chen
Qicong Li
Yuting Ruan
Xudan Yang
Shan Liu
Jie Hu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1464951

3,633 views
3 citations

Original Research

Published on 16 Dec 2024

Association of geriatric nutritional risk index with total testosterone in elderly adults in the US: evidence from NHANES 2011-2016

in Systems Endocrinology

Tanjian Li
Na Jiang
Xin Liang
Xinya Li
Yaqin Li
Yuting Huang
Yu Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1457956

2,389 views
1 citation

Original Research

Published on 11 Dec 2024

Potential candidates from a functional food Zanthoxyli Pericarpium (Sichuan pepper) for the management of hyperuricemia: high-through virtual screening, network pharmacology and dynamics simulations

in Systems Endocrinology

Meilin Chen
Xiaomei Chen
Qinghong Chen
Chenyang Chu
Shuxuan Yang
Chuanghai Wu
Yanting You
Andrew Hung
Angela Wei Hong Yang
Xiaomin Sun

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1436360

4,226 views
5 citations

Original Research

Published on 09 Dec 2024

Associations of systemic inflammation and systemic immune inflammation with serum uric acid concentration and hyperuricemia risk: the mediating effect of body mass index

in Systems Endocrinology

Yueyue Zhang
Shichao Han
Zhizhou Duan
Xu Tian
Xueyi Li
Guangdong Hou
Xuelin Gao
Chunjuan Tian
Xiangyu Li
Wenyuan Yu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1469637

4,727 views
5 citations

Original Research

Published on 29 Nov 2024

Exploring the relationship between air pollution, non-alcoholic fatty liver disease, and liver function indicators: a two-sample Mendelian randomization analysis study

in Systems Endocrinology

Qingliang Song
Jinyue Pan
Maoxing Pan
Chuiyang Zheng
Wen Fan
Jianwei Zhen
Dajin Pi
Zheng Liang
Haiyan Shen
Yuanyou Li

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1396032

4,159 views
4 citations

Original Research

Published on 28 Nov 2024

Association between residual cholesterol and sarcopenia in American adults

in Systems Endocrinology

Jianzhao Li
Yuning Lin

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1461961

4,481 views
8 citations

Original Research

Published on 12 Nov 2024

Relationship between Cardiometabolic index and endometriosis in a US nationally representative sample: results from NHANES 1999-2006

in Systems Endocrinology

Jiarui Hou
Wenting Chen
Rui Wang
Xuchun Huang
Xiaojing Cao
Xiaoyun Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1450965

5,825 views
9 citations

Original Research

Published on 12 Nov 2024

Multi-omic molecular characterization and diagnostic biomarkers for occult hepatitis B infection and HBsAg-positive hepatitis B infection

in Systems Endocrinology

Xinyi Jiang
Jinyue Tian
Li Song
Jiao Meng
Zhenkun Yang
Weizhen Qiao
Jian Zou

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1409079

3,588 views
1 citation

Original Research

Published on 12 Nov 2024

Causal links of human serum metabolites on the risk of prostate cancer: insights from genome-wide Mendelian randomization, single-cell RNA sequencing, and metabolic pathway analysis

in Systems Endocrinology

Renbing Pan
Jingwen Liu
Mingjia Xiao
Chuanyang Sun
Jianyong Zhu
Lijun Wan
Boxin Xue

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1443330

3,570 views
3 citations

Original Research

Published on 08 Nov 2024

Genetically predicted serum ferritin mediates the association between inflammatory cytokines and non-alcoholic fatty liver disease

in Systems Endocrinology

XiaoQian Liu
JianHong Jin
BaoFa Wang
LinPu Ge

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1437999

3,176 views
1 citation

Original Research

Published on 29 Oct 2024

Investigating the mechanisms of resveratrol in the treatment of gouty arthritis through the integration of network pharmacology and metabolics

in Systems Endocrinology

Xiaomin Xu
Donghua Yu
Yu Wang
Xin Jiang
Fang Lu
Shumin Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1438405

5,073 views
1 citation

Original Research

Published on 23 Oct 2024

Deciphering the role of lipid metabolism-related genes in Alzheimer’s disease: a machine learning approach integrating Traditional Chinese Medicine

in Systems Endocrinology

KeShangJing Wu
QingSong Liu
KeYu Long
XueQing Duan
XianYu Chen
Jing Zhang
Li Li
Bin Li

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1448119

6,502 views
5 citations

Original Research

Published on 22 Oct 2024

Causal relationships of familial hypercholesterolemia with the risk of multiple vitamin deficiencies: a Mendelian randomization study

in Systems Endocrinology

Cheng Zhang
Gang Wei
Huan Zhou
Lin Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1401260

3,455 views
2 citations

Original Research

Published on 14 Oct 2024

Association of dietary and circulating antioxidant vitamins with metabolic syndrome: an observational and Mendelian randomization study

in Systems Endocrinology

Qian Sun
Zhixing Fan
Fangfang Yao
Xiaojing Zhao
Min Jiang
Mudan Yang
Menglu Mao
Chaojun Yang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1446719

5,055 views
5 citations

Original Research

Published on 08 Oct 2024

Advancing non-alcoholic fatty liver disease prediction: a comprehensive machine learning approach integrating SHAP interpretability and multi-cohort validation

in Systems Endocrinology

Bo Yang
Huaguan Lu
Yinghui Ran

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1450317

8,368 views
12 citations

Original Research

Published on 30 Sep 2024

Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study

in Systems Endocrinology

Runzhou Ma
Chengming Chen
Ziyi Wang
Huaibin Guo
Wanxing Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1415474

3,221 views
2 citations

Original Research

Published on 19 Sep 2024

Exploring the causal effects of serum lipids and lipidomes on lewy body dementia: a Mendelian randomization study

in Systems Endocrinology

Qingan Fu
Guanrui Pan
Qingyun Yu
Zhekang Liu
Tianzhou Shen
Xiaowei Ma
Long Jiang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1456005

4,400 views
6 citations

Original Research

Published on 16 Sep 2024

Utilize proteomic analysis to identify potential therapeutic targets for combating sepsis and sepsis-related death

in Systems Endocrinology

Tianlong Zhang
Yin Shi
Jiayue Li
Peiyao Huang
Kun Chen
Jiali Yao

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1448314

6,343 views
4 citations

Original Research

Published on 14 Aug 2024

Dissecting the mediating role of inflammatory factors in the interaction between metabolites and sepsis: insights from bidirectional Mendelian randomization

in Systems Endocrinology

Fangchen Gong
Wenbin Liu
Lei Pei
Xiaofeng Wang
Xiangtao Zheng
Song Yang
Shanzhi Zhao
Dan Xu
Ranran Li
Zhitao Yang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1377755

3,528 views

Original Research

Published on 08 Aug 2024

From serum metabolites to the gut: revealing metabolic clues to susceptibility to subtypes of Crohn’s disease and ulcerative colitis

in Systems Endocrinology

Fan Li
Zhaodi Wang
Tongyu Tang
Qi Zhao
Zhi Wang
Xiaoping Han
Zifeng Xu
Yu Chang
Hongyan Li
Sileng Hu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1375896

4,276 views
1 citation

Original Research

Published on 30 Jul 2024

Plasma aldosterone concentrations elevation in hypertensive patients: the dual impact on hyperuricemia and gout

in Systems Endocrinology

Shuaiwei Song
Xintian Cai
Junli Hu
Qing Zhu
Di Shen
Huimin Ma
Yingying Zhang
Rui Ma
Pan Zhou
Wenbo Yang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1424207

3,823 views
34 citations

Original Research

Published on 08 Jul 2024

The predictive role of the platelet-to-lymphocyte ratio for the risk of non-alcoholic fatty liver disease and cirrhosis: a nationwide cross-sectional study

in Systems Endocrinology

Cheng Yan
Weichang Zhang
Yangyan Xiao
Yuxin Sun
Xinke Peng
Wenwu Cai

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1376894

4,351 views
10 citations

Original Research

Published on 04 Jul 2024

Causal impact of human blood metabolites and metabolic pathways on serum uric acid and gout: a mendelian randomization study

in Systems Endocrinology

Yan Zhong
ChengAn Yang
BingHua Zhang
YingWen Chen
WenJun Cai
GuoChen Wang
ChangWei Zhao
WenHai Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1378645

5,574 views
6 citations

439 articles

articles

Association between the Fatty Liver Index (FLI) and incident coronary heart disease: insights from a cohort study on the Chinese population

Circulating irisin levels in patients with MAFLD: an updated systematic review and meta-analysis

Association of geriatric nutritional risk index with total testosterone in elderly adults in the US: evidence from NHANES 2011-2016

Potential candidates from a functional food Zanthoxyli Pericarpium (Sichuan pepper) for the management of hyperuricemia: high-through virtual screening, network pharmacology and dynamics simulations

Associations of systemic inflammation and systemic immune inflammation with serum uric acid concentration and hyperuricemia risk: the mediating effect of body mass index

Exploring the relationship between air pollution, non-alcoholic fatty liver disease, and liver function indicators: a two-sample Mendelian randomization analysis study

Association between residual cholesterol and sarcopenia in American adults

Relationship between Cardiometabolic index and endometriosis in a US nationally representative sample: results from NHANES 1999-2006

Multi-omic molecular characterization and diagnostic biomarkers for occult hepatitis B infection and HBsAg-positive hepatitis B infection

Causal links of human serum metabolites on the risk of prostate cancer: insights from genome-wide Mendelian randomization, single-cell RNA sequencing, and metabolic pathway analysis

Genetically predicted serum ferritin mediates the association between inflammatory cytokines and non-alcoholic fatty liver disease

Investigating the mechanisms of resveratrol in the treatment of gouty arthritis through the integration of network pharmacology and metabolics

Deciphering the role of lipid metabolism-related genes in Alzheimer’s disease: a machine learning approach integrating Traditional Chinese Medicine

Causal relationships of familial hypercholesterolemia with the risk of multiple vitamin deficiencies: a Mendelian randomization study

Association of dietary and circulating antioxidant vitamins with metabolic syndrome: an observational and Mendelian randomization study

Advancing non-alcoholic fatty liver disease prediction: a comprehensive machine learning approach integrating SHAP interpretability and multi-cohort validation

Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study

Exploring the causal effects of serum lipids and lipidomes on lewy body dementia: a Mendelian randomization study

Utilize proteomic analysis to identify potential therapeutic targets for combating sepsis and sepsis-related death

Dissecting the mediating role of inflammatory factors in the interaction between metabolites and sepsis: insights from bidirectional Mendelian randomization

From serum metabolites to the gut: revealing metabolic clues to susceptibility to subtypes of Crohn’s disease and ulcerative colitis

Plasma aldosterone concentrations elevation in hypertensive patients: the dual impact on hyperuricemia and gout

The predictive role of the platelet-to-lymphocyte ratio for the risk of non-alcoholic fatty liver disease and cirrhosis: a nationwide cross-sectional study

Causal impact of human blood metabolites and metabolic pathways on serum uric acid and gout: a mendelian randomization study