Frontiers in Endocrinology

Original Research

Published on 03 Nov 2025

Comprehensive transcriptomic profiling reveals tissue-specific molecular signatures and dysregulated pathways in human diabetic foot ulcers

Guangrong Hu
Ayesha Nisar
Sawar Khan
Wen Li
Enfang Zhu
Haoling Cui
Guiqin Zhang
Yonghan He
Hui Sun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1669205

2,593 views
1 citation

Review

Published on 03 Nov 2025

Harnessing gut-derived bioactives and AI diagnostics for the next generation of type 2 diabetes solutions

Yuliya Tseyslyer
Vladyslav Malyi
Mariia Saifullina
Olena Tsyryuk
Yuliia Shvets
Yurii Penchuk
Iryna Kovalchuk
Oleksandr Kovalchuk
Oleksandr Korotkyi
Volodymyr Bulda

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1699954

3,024 views

Original Research

Published on 03 Nov 2025

Relationship between plasma atherogenic index and subclinical hypothyroidism: an analysis of NHANES data and animal experiment

Qiwei Chen
Yuwan Li
Yi Ruan
Linxi Jin
Shuhong Yao
Zhuang Han
Xinmiao Hong
Zhita Wang
Liang Li
Weidong He

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1700853

1,721 views

Original Research

Published on 03 Nov 2025

Development of a risk prediction model for gastrointestinal adverse events associated with semaglutide administration in patients with type 2 diabetes mellitus

Deyong Yue
Xuesheng Hua
Ling Zhu
Jun Wang
Lihua Gu
Zhengxia Yuan
Wenle Jian
Yirong Chen
Guoliang Meng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1684395

2,310 views
1 citation

Systematic Review

Published on 03 Nov 2025

Comparative efficacy and safety of anti-osteoporotic therapies for kidney transplant recipients: a systematic review and network meta-analysis

Xiaopei Liu
Xingyao Li
Yanhong Zhao
Qi Gao
Yuan Xue
Zhongheng Wu
Xingmin Shi
Xili Wu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1689233

2,109 views

Original Research

Published on 03 Nov 2025

Thyroid autoimmunity at onset of type 1 diabetes as a predictor of thyroid dysfunction: a thirty-years retrospective longitudinal study

Gemma Carreras
Lilian C. Mendoza
Cristina Colom
Mireia Tirado-Capistros
Helena Sardà
José Luis Sánchez-Quesada
Antonio Pérez

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1699111

1,564 views

Case Report

Published on 03 Nov 2025

Case Report: NEUROD1 c.-108G>C mutation in a ketosis-prone MODY6 patient: implications for genetic testing and DPP-4 inhibitor therapy

Zhuhai Shao
Lili Xu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1673765

1,226 views

Review

Published on 03 Nov 2025

Dysregulated bile acid metabolism as a novel player in gout progression: emerging therapeutic strategies

Hui Sun
Le Yang
Ye Sun
Xinya Zhang
Xin Sun
Xueping Zhao
Hui Sun
Qimeng Zhang
Guangli Yan
Xijun Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1676017

2,699 views

Original Research

Published on 03 Nov 2025

Threshold effect and age interaction of TyG index on diabetes incidence in normolipidemic population: a multicenter cohort study

Hongchao Chen
Qi Chen
Li Xia
Songyao Lu
Xiaohong Cai
Xudong Huang
Juan Wu
Weihan Lin

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1645344

1,248 views

Original Research

Published on 03 Nov 2025

The usefulness of a body shape index in assessing muscle function and strength in older adults hemodialysis patients

Bojan Knap
Boštjan Žvanut
Lucija Brezočnik
Mihaela Jurdana

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1585193

1,282 views

Systematic Review

Published on 03 Nov 2025

Bayesian network meta-analysis of the impact of exercise therapy on blood glucose in type 2 diabetes patients

Hairong Liu
Wenli Wang
Jing Sun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1658739

2,148 views

Systematic Review

Published on 03 Nov 2025

The predictive value of immune inflammation indexes for the risk of fracture in patients with osteoporosis: a systematic review and meta-analysis

Yawei Xu
Xiaoming He
Xu Zhang
Shilong Meng
Chengjie Wang
Yifeng Yuan
Xiaolin Shi
Kang Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1650895

2,306 views

Original Research

Published on 03 Nov 2025

Real-world insights from acute management of potassium disorders in diabetic ketoacidosis

Yue Zhang
Jing Li
Shanshan Deng
Yongjing Zhang
Manli Guo
Fangfang Jiang
Lingguang Luo
Yanqing He
Shaogang Ma
Yigen Peng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1669400

2,531 views
1 citation

Review

Published on 03 Nov 2025

PLINs-mediated organelle interactions: a key of exercise-mediated improvement of skeletal muscle lipid metabolism disorders

Zhiyuan Liu
Yungang Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1700668

2,197 views

Review

Published on 03 Nov 2025

New approach to optimize therapy in type 2 diabetes mellitus: the importance of subclassification

María José Reyes-Medina
Vanesa Cantón-Habas
Francisco Javier Sánchez-Jiménez
Enrique Molina-Hurtado
María del Pilar Carrera-González

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1710511

3,076 views

Original Research

Published on 03 Nov 2025

Arginine vasotocin is a player in the multifactorial control of spermatogenesis in zebrafish

Maya Zanardini
Nicolas Parker
Yifei Ma
Hamid R. Habibi

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1672823

1,051 views
1 citation

Mini Review

Published on 03 Nov 2025

Integrating gut microbiota into multidisciplinary perspectives on diabetic neuropathy

Maksym Horiachok
Kateryna Potapova
Taras Ivanykovych
Viktoria Yerokhovych
Yeva Ilkiv
Larysa Sokolova

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1710868

1,844 views

Original Research

Published on 03 Nov 2025

U-TXM: a novel biomarker for early detection of diabetic kidney disease

Yujie Jin
Jiahao Xu
Yan Ma
Chunchen Ni
Yan Yao
Shujuan Shang
Mengru Wang
Chunyan Xing
Song Dong
Chaoqun Xiong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1682136

1,280 views

Systematic Review

Published on 03 Nov 2025

Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis

Hong Xu
Yujie Liang
Peishan Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1641563

1,606 views

Mini Review

Published on 03 Nov 2025

Peritoneal implantation of pheochromocytoma – pheochromocytomatosis: a case report and mini review

Erik Bényei
András Laki
Gergely Kiss
Zsolt Varga
Miklós Tóth
Judit Tőke

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1679629

1,262 views

Opinion

Published on 31 Oct 2025

Nutrition therapy in the era of automated insulin delivery

Meryem K. Talbo
Franziska K. Bishop
Daria Igudesman
Karen D. Corbin
Angelica Cristello Sarteau
Elizabeth J. Mayer-Davis
David M. Maahs

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1690486

1,931 views

Original Research

Published on 31 Oct 2025

PNPLA3-Ile148Met and TM6SF2-Glu167Lys increase susceptibility to metabolic dysfunction-associated steatotic liver disease in children

Hengpan Yao
Zhiyi Xia
Yijing Liu
MengJun Dong
Kairui Yang
Fang Zhou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1689656

1,475 views

Original Research

Published on 31 Oct 2025

From awareness to action: evolving endocrinologist practices in obesity treatment in Italy

Marco Chianelli
Luca Busetto
Roberto Attanasio
Rinaldo Guglielmi
Renato Cozzi
Franco Grimaldi
Andrea Frasoldati
Agnese Persichetti
Enrico Papini
Antonio Nicolucci

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1705670

1,315 views
1 citation

Review

Published on 31 Oct 2025

The gut–adipose/pancreas axis: a novel perspective on glycolipid metabolism dysregulation in MAFLD and T2DM pathogenesis

Jiahui Liang
Xingyu Chen
Yunhang Chu
Yan Leng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1664233

3,983 views
1 citation

19,013 Publications

volumes

Volume 16 - 2025

Comprehensive transcriptomic profiling reveals tissue-specific molecular signatures and dysregulated pathways in human diabetic foot ulcers

Harnessing gut-derived bioactives and AI diagnostics for the next generation of type 2 diabetes solutions

Relationship between plasma atherogenic index and subclinical hypothyroidism: an analysis of NHANES data and animal experiment

Development of a risk prediction model for gastrointestinal adverse events associated with semaglutide administration in patients with type 2 diabetes mellitus

Comparative efficacy and safety of anti-osteoporotic therapies for kidney transplant recipients: a systematic review and network meta-analysis

Thyroid autoimmunity at onset of type 1 diabetes as a predictor of thyroid dysfunction: a thirty-years retrospective longitudinal study

Case Report: NEUROD1 c.-108G>C mutation in a ketosis-prone MODY6 patient: implications for genetic testing and DPP-4 inhibitor therapy

Dysregulated bile acid metabolism as a novel player in gout progression: emerging therapeutic strategies

Threshold effect and age interaction of TyG index on diabetes incidence in normolipidemic population: a multicenter cohort study

The usefulness of a body shape index in assessing muscle function and strength in older adults hemodialysis patients

Bayesian network meta-analysis of the impact of exercise therapy on blood glucose in type 2 diabetes patients

The predictive value of immune inflammation indexes for the risk of fracture in patients with osteoporosis: a systematic review and meta-analysis

Real-world insights from acute management of potassium disorders in diabetic ketoacidosis

PLINs-mediated organelle interactions: a key of exercise-mediated improvement of skeletal muscle lipid metabolism disorders

New approach to optimize therapy in type 2 diabetes mellitus: the importance of subclassification

Arginine vasotocin is a player in the multifactorial control of spermatogenesis in zebrafish

Integrating gut microbiota into multidisciplinary perspectives on diabetic neuropathy

U-TXM: a novel biomarker for early detection of diabetic kidney disease

Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis

Peritoneal implantation of pheochromocytoma – pheochromocytomatosis: a case report and mini review

Nutrition therapy in the era of automated insulin delivery

PNPLA3-Ile148Met and TM6SF2-Glu167Lys increase susceptibility to metabolic dysfunction-associated steatotic liver disease in children

From awareness to action: evolving endocrinologist practices in obesity treatment in Italy

The gut–adipose/pancreas axis: a novel perspective on glycolipid metabolism dysregulation in MAFLD and T2DM pathogenesis