Frontiers in Endocrinology

Original Research

Published on 17 Dec 2025

Development and validation of an explainable machine learning and nomogram model for early detection and risk stratification of polycystic ovary syndrome: a multicenter study

Bihua Yao
Xingyu Yu
Yunyan Zhang
Jiayan Chen
Xiaotong Zhu
Cheng Zhang
Tong Jijun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1719631

512 views

Original Research

Published on 17 Dec 2025

Configurational paths to promoting physical activity among older adults with type 2 diabetes in China: an fsQCA study based on the multi-theory model

Bo Zhang
Panpan Huai
Jintao Wang
Linghui Zhang
Jinli Guo

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1673625

450 views

Review

Published on 17 Dec 2025

Research progress of gut microbiota and its metabolites in polycystic ovary syndrome

Shiyi Qin
Shimeng Guo
Xinmiao Tan
Ke Li
Jiayu Huang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1700191

564 views

Original Research

Published on 17 Dec 2025

Correlation between intrasellar pressure, pituitary adenoma invasiveness, pituitary dysfunction, and apoplexy

Shan Xie
Zhilin Shao
Dongqi Shao
Xialin Zheng
Huadong Tang
Yu Li
Renhao Zhang
Tianyang Wu
Hao Lang
Rui Xu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1700711

535 views

Correction

Published on 17 Dec 2025

Correction: Comparative analysis of the therapeutic effect of antibiotic bone cement on Wagner grade 3 or 4 diabetic foot ulcer in heel and non-heel areas: a retrospective cohort study

Yang Jian
Li Li
Wei Chen
Wenyu An
Runxue Guan
Yanji Zhang
Jiarui Wei
Shusen Chang
Jian Zhou
Kaiyu Nie

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1762804

216 views

Original Research

Published on 17 Dec 2025

Inulin and Lycium barbarum polysaccharides mitigate the diabetic inflammatory response by modulating bile acid metabolism to enhance regulatory T cell (Treg) activation in a rat model of diabetes

Haixia Lu
Hongyan Luo
Peiling Li
Yan Yang
Shilu Cao
Yanfang Zhang
Hongxia Ma
Qian Zhao
Yali Zheng
Hao Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1705635

403 views

Original Research

Accepted on 16 Dec 2025

Objective perimetry and diabetic retinopathy progression: A 10-year follow-up study

Betelhem Temesgen Yibekal
Bhim Bahadur Rai
Joshua Van P Kleef
Faran Sabeti
Emilie MF Rohan
Christopher J Nolan
Ted Maddess

Frontiers in Endocrinology

183 views

Original Research

Accepted on 16 Dec 2025

Impact of Pre-Therapeutic Fasting Plasma Glucose on Survival Outcomes in Advanced Non-Small Cell Lung Cancer Patients

Feiwen Liu
Luo Min
Fang Wang
Ting Liang
Wang Xiaochen

Frontiers in Endocrinology

Original Research

Accepted on 16 Dec 2025

Gender-Specific Associations Between Neutrophil Levels and Refracture Risks: A Retrospective Cohort Study

Shuai Yuan
Xiao-Jie Zhou
Hao-Tian Jiao
Yaqin Gong
Jian Jin
Yan Cao
Ke Lu
Chong Li

Frontiers in Endocrinology

189 views

Original Research

Accepted on 16 Dec 2025

Development and external validation of models to improve prediction of osteoporosis in elderly women :interpretable machine learning

Tian Tang
Shiwen Wang
Shengziyi Cai
Yun Hu

Frontiers in Endocrinology

132 views

Original Research

Accepted on 16 Dec 2025

Remnant Cholesterol: An Independent, Dose-Dependent Risk Factor for Hyperuricemia in a Normolipidemic Chinese Population

XIONG HUALI
Ma Fengxun

Frontiers in Endocrinology

Original Research

Accepted on 16 Dec 2025

Non-HDL-C/HDL-C Ratio (NHHR) and N-Terminal Pro-B-Type Natriuretic Peptide in the general and hospital-based population: a cross-sectional validation study

Haitao Xie
Li Jianghong
Le Shen
Peng Yu
Shi Wang
Xiaohu Chen
Shuhua Tang

Frontiers in Endocrinology

130 views

Original Research

Accepted on 16 Dec 2025

Overweight worsens the metabolic presentation of type 1 diabetes mellitus in children

Eszter Muzslay
Vivien Herczeg
Rozália Ildikó Pusztai
Vilmos Zoltán Forstreuter
Dorina Soós
Johanna Takács
Péter Tóth-Heyn
Andrea Luczay

Frontiers in Endocrinology

284 views

Original Research

Accepted on 16 Dec 2025

Noninvasive Prediction of T-Score in IgA Nephropathy Using Machine Learning within the Oxford Classification System

Jingyu Dou
Shuhua Jin
Xiaoyue Ma
Lijie Zhang
Lu Wen
Qianqian Li
Jinjin Hai
Bin Yan
Genyang Cheng

Frontiers in Endocrinology

252 views

Correction

Accepted on 16 Dec 2025

Correction: Quantifying the link: coronary artery inflammation via CCTA-derived fat attenuation index and its association with diabetes duration

Frontiers Production Office

Frontiers in Endocrinology

General Commentary

Accepted on 16 Dec 2025

Commentary: "FSH receptor N680S genotype-guided gonadotropin choice increases cumulative pregnancy and live birth rates after in vitro fertilization"

Livio Casarini
Manuela Simoni

Frontiers in Endocrinology

103 views

Original Research

Accepted on 16 Dec 2025

Ethnic Disparities in Metabolic Dysfunction-Associated Steatotic Liver Disease and Clinical Outcomes

Yusuke Miyatani
Aoi Ogawa
Tomoki Sempokuya
Chuong Tran
Davis James
Todd Seto
Cecilia Shikuma
Scott Kuwada

Frontiers in Endocrinology

130 views

Original Research

Accepted on 16 Dec 2025

Resistance Training as a Key Strategy for High-Quality Weight Loss in Men and Women

Yair Lahav
Yftach Gepner

Frontiers in Endocrinology

111 views

Clinical Trial

Published on 16 Dec 2025

Telehealth insulin titration in adults with diabetes: a randomized controlled trial comparing bluetooth-enabled versus traditional glucometers

Xia Lian
Hui Ling Liew
Ying Shan Lee
Anita Ying Lin
Eunice Yu Wen Goh
Christina Yang Hoon Goh
Hwee Chen Quek
Isaac Jun Song Tan
Helen Lim
Ying Jie Chee

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1724811

582 views

Original Research

Published on 16 Dec 2025

Molecular characterization of the murine Leydig cell lines TM3 and MLTC-1

Sarah K. Schröder-Lange
Katharina S. Hardt
Diandra T. Keller
Manuela Pinoé-Schmidt
Eva M. Buhl
Ralf Weiskirchen

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1715307

861 views

Review

Published on 16 Dec 2025

Adipose-androgen crosstalk in polycystic ovary syndrome: mechanisms and therapeutic implications

Muchu Ni
Hongyan Lei
Tao Ye
Yongzhou Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1731179

463 views

Systematic Review

Published on 16 Dec 2025

Efficacy and safety of insulin efsitora in type 2 diabetes: a meta-analysis of randomized controlled trials

Yang Liu
Dingtao Chen
Ke He
Jichao Wei
Miao Liang
Li Han
Jingxin Li
Xuejing Li
Xianying Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1608458

786 views

Original Research

Published on 16 Dec 2025

Diabetes as an independent risk factor for severe inflammatory bowel disease: evidence from an inflammation–metabolism–liver coupling framework

Bin Huang
Honglin An
Liming Chen
Yiman Qiu
Yaping Su
Shiju Shen
Huaping Wu
Mengyuan Li
Lisha Lu
Rong Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1707507

474 views

Review

Published on 16 Dec 2025

The role of PPARγ in cancer cachexia: friend or foe?

Leili Ding
Hao Jiang
Liang Shen
Yiming Xu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1717134

476 views

2,758 Publications

volumes

Development and validation of an explainable machine learning and nomogram model for early detection and risk stratification of polycystic ovary syndrome: a multicenter study

Configurational paths to promoting physical activity among older adults with type 2 diabetes in China: an fsQCA study based on the multi-theory model

Research progress of gut microbiota and its metabolites in polycystic ovary syndrome

Correlation between intrasellar pressure, pituitary adenoma invasiveness, pituitary dysfunction, and apoplexy

Correction: Comparative analysis of the therapeutic effect of antibiotic bone cement on Wagner grade 3 or 4 diabetic foot ulcer in heel and non-heel areas: a retrospective cohort study

Inulin and Lycium barbarum polysaccharides mitigate the diabetic inflammatory response by modulating bile acid metabolism to enhance regulatory T cell (Treg) activation in a rat model of diabetes

Objective perimetry and diabetic retinopathy progression: A 10-year follow-up study

Impact of Pre-Therapeutic Fasting Plasma Glucose on Survival Outcomes in Advanced Non-Small Cell Lung Cancer Patients

Gender-Specific Associations Between Neutrophil Levels and Refracture Risks: A Retrospective Cohort Study

Development and external validation of models to improve prediction of osteoporosis in elderly women :interpretable machine learning

Remnant Cholesterol: An Independent, Dose-Dependent Risk Factor for Hyperuricemia in a Normolipidemic Chinese Population

Non-HDL-C/HDL-C Ratio (NHHR) and N-Terminal Pro-B-Type Natriuretic Peptide in the general and hospital-based population: a cross-sectional validation study

Overweight worsens the metabolic presentation of type 1 diabetes mellitus in children

Noninvasive Prediction of T-Score in IgA Nephropathy Using Machine Learning within the Oxford Classification System

Correction: Quantifying the link: coronary artery inflammation via CCTA-derived fat attenuation index and its association with diabetes duration

Commentary: "FSH receptor N680S genotype-guided gonadotropin choice increases cumulative pregnancy and live birth rates after in vitro fertilization"

Ethnic Disparities in Metabolic Dysfunction-Associated Steatotic Liver Disease and Clinical Outcomes

Resistance Training as a Key Strategy for High-Quality Weight Loss in Men and Women

Telehealth insulin titration in adults with diabetes: a randomized controlled trial comparing bluetooth-enabled versus traditional glucometers

Molecular characterization of the murine Leydig cell lines TM3 and MLTC-1

Adipose-androgen crosstalk in polycystic ovary syndrome: mechanisms and therapeutic implications

Efficacy and safety of insulin efsitora in type 2 diabetes: a meta-analysis of randomized controlled trials

Diabetes as an independent risk factor for severe inflammatory bowel disease: evidence from an inflammation–metabolism–liver coupling framework

The role of PPARγ in cancer cachexia: friend or foe?