Frontiers in Endocrinology

Hypothesis and Theory

Published on 11 Feb 2026

Does childhood obesity foreshadow a future time-bomb of early and more aggressive cancers?

Jeff M. P. Holly
Katherine Samaras

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1674961

491 views

Mini Review

Published on 11 Feb 2026

Implication of xanthine oxidoreductase in oxidative stress-related chronic diseases

Kendra L. Nelson
Venkata Saroja Voruganti

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1662037

423 views

Original Research

Published on 10 Feb 2026

Loss of the PDLIM2 protein during chronic colitis promotes inflammation, impaired epithelium recovery, alterations to the microbiome and oxidative stress

Stephanie Ward
Orla T. Cox
Sara Roggiani
Tadgh Crowley
Silvia Turroni
Silvia Melgar
Rosemary O’Connor

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1720162

545 views

Original Research

Published on 09 Feb 2026

Testosterone plus lifestyle therapy improves skeletal muscle glycolysis in older men with obesity and hypogonadism

Viola Viola
Marlene Aguilar
Maria Liza Duremdes Nava
Alessandra Celli
Reina Armamento-Villareal
Yoann Barnouin
Nicola Napoli
Nagireeddy Putluri
Clifford Qualls
Dennis T. Villareal

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1719749

882 views

Review

Published on 06 Feb 2026

Unraveling the metabolic pathways between atherosclerosis and sarcopenia

Mei Yu
Lichao Ge
Chen Fu
Rujia Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1762825

591 views

Original Research

Published on 03 Feb 2026

Early postnatal changes in thyroid-stimulating hormone and subsequent neurodevelopment in preterm infants

Myoung-Jin Yoo
Yong Hun Jang
Gang-Yi Lee
Habyeong Kang
Dong Hye Ye
Woochang Hwang
Seung Yang
Hyun Ju Lee

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1745327

587 views

Review

Published on 03 Feb 2026

An expert narrative review on the mechanisms and therapeutic potential of gut microbiota-derived metabolites in multi-organ crosstalk

Yushu Zhang
Xuebin Cao
Shihong Xiong
Wenqi Zhen
Yang Yang
Na Gong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1706353

645 views

Review

Published on 02 Feb 2026

Branched-chain amino acids and insulin resistance in type 2 diabetes: from metabolic dysregulation to therapeutic targets

Jie Mei
Fu-yuan Yang
Quan Gong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1643231

688 views

Editorial

Published on 30 Jan 2026

Editorial: Lifestyle and environmental factors and human fertility

María Laura Ribeiro

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1771853

660 views

Original Research

Published on 30 Jan 2026

Associations of METS-VF and BRI with risk of osteoarthritis in patients with diabetes or prediabetes: evidence from the NHANES 1999–2020

Wanqing Ye
Lei Wei
Zheng Wang
Yinghu Deng
Zhixiang Ma
Wei Ling
Jun Mei
Yinpeng Dong
Xiaosi Zhang
Chao Miao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1690153

366 views

Original Research

Published on 28 Jan 2026

Placental mRNA and miRNA dynamics associated with lipid metabolism pathways in pregnancies affected by obesity

Ruggero Spadafora
Jiayi Zhang
N. R. Nirmala
Xue Li
Perrie O’Tierney-Ginn

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1736033

839 views

Mini Review

Published on 28 Jan 2026

Lymphatic metastasis of papillary thyroid carcinoma: mechanism and clinicopathological physiology

Pu Liu
Xianqiang Yu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1725077

738 views

Original Research

Published on 28 Jan 2026

Association between metabolic dysfunction-associated fatty liver disease and cardiovascular autonomic neuropathy in type 2 diabetes

Rong Peng
Yaoyun Ao
Enni Cen
Junnian Chen
Zeshan Huang
Xiaoying Fu
Jian Kuang
Shuiqing Lai
Shuting Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1711660

513 views

Clinical Trial

Published on 28 Jan 2026

Maintained diabetes remission among normal BMI individuals achieved without ongoing intervention: a three-year follow-up study of intermittent calorie restriction

Ruiyu Wu
Xiao Yang
Xu Zhou
Zhiyong Xiao
Xuan Chen
Jiali Zhou
Jian Li
Zhuoming Yin
Xihu Lai
Tao Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1733840

694 views

Original Research

Published on 28 Jan 2026

Effect of timely diagnosis and treatment on growth and body proportionality of children with congenital hypothyroidism

Aditya Kochar
Harvinder Kaur
Devi Dayal

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1713739

498 views

Original Research

Published on 27 Jan 2026

TyG index and MAFLD severity are associated with subclinical LV dysfunction in T2DM patients: a cross−sectional study

Xiangsui Hu
Hanwei Chen
Ziying Wang
Yun Deng
Long Huang
Chunquan Zhang
Liangyun Guo
Shengbo Liu
Lingmin Liao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1749989

600 views

Systematic Review

Published on 27 Jan 2026

Diagnostic accuracy of machine learning for endometriosis: a systematic review and meta-analysis

Bingyi Zhang
Xiaoli Lv
Dan Li
Longtao Zhang
Ziyang Ru
Yuxia Ma

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1735567

862 views

Original Research

Published on 27 Jan 2026

Multi-gene co-mutations of BRAF with TERT, PIK3CA, or TP53 are powerful predictors of central lymph node metastasis in papillary thyroid carcinoma

Qing Yu
Han Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1728045

816 views

Original Research

Published on 27 Jan 2026

Efficacy and safety of sodium-glucose cotransporter 2 inhibitors in the treatment of diabetic kidney disease: a meta-analysis

Yingbo Guo
Wenfeng Gao
Shichao Li
Xiaona An
Zhongjie Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1596888

594 views

Mini Review

Published on 26 Jan 2026

Management strategies for isolated premature thelarche: a risk-stratified clinical pathway favoring “watchful waiting”

Yan Xu
Hongtao Cui
Xinna Wang
Fang Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1705194

789 views

Original Research

Published on 26 Jan 2026

From data to decision: an interpretable machine learning model for optimizing RAI therapy in Graves’ hyperthyroidism

Lu Lu
Xiaojuan Wei
Yan Chen
Dongyun Meng
Shaozhou Mo
Zeyong Sun
Fengyang Song
Kehua Liao
Wentan Huang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1711029

749 views

Mini Review

Published on 26 Jan 2026

How hypoxia-induced diabetes develops and is maintained in children born preterm

Eung-Kwon Pae
Ronald M. Harper

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1720875

926 views

Original Research

Published on 26 Jan 2026

A meta-analysis of serum uric acid and diabetic nephropathy risk in type 2 diabetes

Jing Zhao
Lingzhu Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1651446

701 views

Mini Review

Published on 26 Jan 2026

The pathogenesis, therapeutic targets and drugs of polycystic ovary syndrome

Yawen Chen
Xiaoxiang Sun
Xuan Xia
Kaiqi Chen
Fang Zeng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1722649

1,152 views

2,755 Publications

volumes

Does childhood obesity foreshadow a future time-bomb of early and more aggressive cancers?

Implication of xanthine oxidoreductase in oxidative stress-related chronic diseases

Loss of the PDLIM2 protein during chronic colitis promotes inflammation, impaired epithelium recovery, alterations to the microbiome and oxidative stress

Testosterone plus lifestyle therapy improves skeletal muscle glycolysis in older men with obesity and hypogonadism

Unraveling the metabolic pathways between atherosclerosis and sarcopenia

Early postnatal changes in thyroid-stimulating hormone and subsequent neurodevelopment in preterm infants

An expert narrative review on the mechanisms and therapeutic potential of gut microbiota-derived metabolites in multi-organ crosstalk

Branched-chain amino acids and insulin resistance in type 2 diabetes: from metabolic dysregulation to therapeutic targets

Editorial: Lifestyle and environmental factors and human fertility

Associations of METS-VF and BRI with risk of osteoarthritis in patients with diabetes or prediabetes: evidence from the NHANES 1999–2020

Placental mRNA and miRNA dynamics associated with lipid metabolism pathways in pregnancies affected by obesity

Lymphatic metastasis of papillary thyroid carcinoma: mechanism and clinicopathological physiology

Association between metabolic dysfunction-associated fatty liver disease and cardiovascular autonomic neuropathy in type 2 diabetes

Maintained diabetes remission among normal BMI individuals achieved without ongoing intervention: a three-year follow-up study of intermittent calorie restriction

Effect of timely diagnosis and treatment on growth and body proportionality of children with congenital hypothyroidism

TyG index and MAFLD severity are associated with subclinical LV dysfunction in T2DM patients: a cross−sectional study

Diagnostic accuracy of machine learning for endometriosis: a systematic review and meta-analysis

Multi-gene co-mutations of BRAF with TERT, PIK3CA, or TP53 are powerful predictors of central lymph node metastasis in papillary thyroid carcinoma

Efficacy and safety of sodium-glucose cotransporter 2 inhibitors in the treatment of diabetic kidney disease: a meta-analysis

Management strategies for isolated premature thelarche: a risk-stratified clinical pathway favoring “watchful waiting”

From data to decision: an interpretable machine learning model for optimizing RAI therapy in Graves’ hyperthyroidism

How hypoxia-induced diabetes develops and is maintained in children born preterm

A meta-analysis of serum uric acid and diabetic nephropathy risk in type 2 diabetes

The pathogenesis, therapeutic targets and drugs of polycystic ovary syndrome