Frontiers in Genetics

Brief Research Report

Published on 12 Nov 2025

Building capability for clinician-led genomic change: insights from use and non-use of a theory-informed model for change

in ELSI in Science and Genetics

Melissa Martyn
Amy Clarke
Trang Do
Belinda Dawson-McClaren
Clara Gaff

Frontiers in Genetics

doi 10.3389/fgene.2025.1692703

1,846 views
1 citation

Original Research

Published on 12 Nov 2025

The genetic diversity and population structure of native horse breeds in Xinjiang, China

in Livestock Genomics

Chi Tang
Baoyu Yang
Gulibaheti Dawulietihan
Li Xue
Shuyuan Liu
Yinamujiang Yalimaimaiti
Qingzheng Wang
Na Yang
Xiaoyuan Sun
Yaru Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1439312

2,722 views

Correction

Published on 12 Nov 2025

Correction: Drought adaptation index (DAI) based on BLUP as a selection approach for drought-resilient switchgrass germplasm

in Genomics of Plants and the Phytoecosystem

Shiva Om Makaju
Hari Bahadur Chhetri
Chanaka Roshan Abeyratne
Mirko Pavicic
Hari Poudel
Jazib Ali Irfan
Anita Giabardo
Katrien M. Devos
Daniel Jacobson
Ali Mekki Missaoui

Frontiers in Genetics

doi 10.3389/fgene.2025.1731825

789 views

Correction

Published on 12 Nov 2025

Correction: Integrative machine learning and Mendelian randomization identify causal laboratory biomarkers for coronary artery lesions in Kawasaki disease: a prospective study

in Computational Genomics

Hancao Yang
Meng Wu
Keqing Liang
Yi Li
Ran Yang
Beibei Yuan
Ming Wu
Jin Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1735649

824 views

Original Research

Published on 12 Nov 2025

CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation

in Cancer Genetics and Oncogenomics

Jinyu Li
Ning Wang
Jianlei Bi
Meihua Guo
Bingbing Xu
Gena Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1687066

1,900 views

Case Report

Published on 12 Nov 2025

Case Report: Compound heterozygous CEP152 c.3346-5T>C variant and chr15 deletion causing recurrent MCPH–SCKS in a Chinese pregnant woman across two consecutive pregnancies

in Genetics of Common and Rare Diseases

Tao Zhang
Hua Yuan
Xiaoliang Shi
Yao He
Haitao Pan
Yongxing Zhong
Jintang Zhang
Zhen Yang
Yunyan Ke
Yan Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1646297

1,504 views

Original Research

Published on 12 Nov 2025

Computational-experimental strategy identifies Co-upregulated biomarkers linking coronary heart disease and type 2 diabetes pathogenesis

in Genetics of Common and Rare Diseases

Wei Li
Yu Cao
Chen Yu
Bingjun Che
Miao He
Dongbiao Li
Lihong Jiang
Lijing Ma

Frontiers in Genetics

doi 10.3389/fgene.2025.1673303

1,319 views

Review

Published on 11 Nov 2025

Ocular surface health and disease: insight from single-cell RNA sequencing

in Human and Medical Genomics

Shangkun Ou
Minqing Cai
Yuchong Feng
Sijie Lin
Xueer Zheng
Su Zhao
Hao Gu
Yiming Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1683167

2,798 views

Mini Review

Published on 11 Nov 2025

Epigenetic landscape in lysosomal storage disorders: mechanisms and modulation

in Epigenomics and Epigenetics

Andrés Felipe Leal
Harry Pachajoa
Shunji Tomatsu

Frontiers in Genetics

doi 10.3389/fgene.2025.1679497

2,012 views

Original Research

Published on 11 Nov 2025

Germline activating sequence variations in RASopathy spectrum genes: genotype–phenotype correlation in a North Indian cohort

in Genetics of Common and Rare Diseases

Shifali Gupta
Priyanka Srivastava
Roshan Daniel
Chitra Bhardwaj
Parminder Kaur
Pratibha Bawa
Anu Kumari
Ravi Pratap Singh Bhadoriya
Mrinali Peters
Anupriya Kaur

Frontiers in Genetics

doi 10.3389/fgene.2025.1677143

1,888 views
1 citation

Original Research

Published on 10 Nov 2025

Genotyping strategies for single-step genomic predictions in a simulated sheep population under different scenarios of pedigree error types

in Livestock Genomics

Artur O. Rocha
Leonardo S. Gloria
Andre C. Araujo
Hui Wen
Carrie S. Wilson
Bradley A. Freking
Thomas W. Murphy
Joan M. Burke
Ronald M. Lewis
Luiz F. Brito

Frontiers in Genetics

doi 10.3389/fgene.2025.1697103

3,016 views

Original Research

Published on 10 Nov 2025

Unveiling disulfidptosis-linked lncRNA signatures: insights into the immune microenvironment and drug responsiveness in oral squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Xue Meng
Lichao Cao
Yantao Liu
Sihan Wang
Weixian Liu
Guangping Zhang
Siqi Guo
Fangyu Qi
Tingting Wang
Yuhe Xia

Frontiers in Genetics

doi 10.3389/fgene.2025.1650544

1,400 views

Original Research

Published on 10 Nov 2025

Construction of a HSC activation-related lncRNA–miRNA–mRNA ceRNA regulatory network reveals potential molecules involved in liver fibrosis

in RNA

Kaiqiang Wan
Qiong Zhou
Ruirui Feng
Tao Liu
Chang Fan
Xue Pang
Zhongliang Li
Qiumei Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1640326

1,821 views
1 citation

Original Research

Published on 10 Nov 2025

Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) leaves

in Genomics of Plants and the Phytoecosystem

Ting Yang
Xiaolu Lin
Rui Chen
Ruiqi Wang
Tong Li
Fulong Shen
Xiaowei Zhang
Lianghua Lai
Bing Lu
Jiliang Wei

Frontiers in Genetics

doi 10.3389/fgene.2025.1662815

1,781 views
2 citations

Mini Review

Published on 10 Nov 2025

Advances in post-processing methods for multiple sequence alignment

in Computational Genomics

Yixiao Zhai
Zitong Zhang
Zhen Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1722317

2,004 views

Original Research

Published on 07 Nov 2025

KSRV: a Kernel PCA-Based framework for inferring spatial RNA velocity at single-cell resolution

in Computational Genomics

Yan He
Jian Jiang
Huahai Qiu
Ya-Zhou Shi
Ben-Gong Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1695803

1,853 views

Original Research

Published on 07 Nov 2025

Mechanistic insights into NFIX frameshift mutations in Malan syndrome: proteasomal degradation-mediated haploinsufficiency

in Genetics of Common and Rare Diseases

Yan Zhou
Linbing Zou
Yaoyao Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1648420

1,535 views

Correction

Published on 07 Nov 2025

Correction: Identification of shared diagnostic genes between osteoporosis and Crohn’s disease through integrated transcriptomic analysis and machine learning

in Computational Genomics

Guirong Yi
Peng Zhou
Qinxu Yang
Maosheng Zhao
Qiaoqiao Yang
Shensong Li
Chenpo Dang

Frontiers in Genetics

doi 10.3389/fgene.2025.1722642

837 views

Case Report

Published on 07 Nov 2025

Case Report: Whole-exome sequencing revealed a de novo variant in SETBP1 gene in a Chinese family with developmental delay

in Genetics of Common and Rare Diseases

Junlin Pan
Yan Zhang
Jinwei Hou
Na Shi
Huiling Qu
Longhuan Jiang
Haiping Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1637931

1,637 views

Original Research

Published on 07 Nov 2025

BRMS1L promotes chemotherapy sensitivity by inhibiting autophagy in breast cancer

in Cancer Genetics and Oncogenomics

Yuan Li
Dian Zhang
Junhao Zhao
Mei Yang
Yiping Wang
Peiyao Lee
Shaohua Qu

Frontiers in Genetics

doi 10.3389/fgene.2025.1670001

1,648 views

Original Research

Published on 07 Nov 2025

Identifying gene-environment interactions across genome-wide, twin, and polygenic risk score approaches

in Behavioral and Psychiatric Genetics

Brad Verhulst

Frontiers in Genetics

doi 10.3389/fgene.2025.1698381

1,850 views

Original Research

Published on 07 Nov 2025

ST8SIA6-AS1 serves as a prognostic biomarker in cancer and exhibits oncogenic properties in prostate cancer

in RNA

Yaoan Wen
Jiangbin Yang
Shuyuan Zhan
Yuanjing Huang
Guoqiang Chen
Song Zheng
Shaoxing Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1648077

1,503 views

Correction

Published on 07 Nov 2025

Correction: A novel splicing variant in NBAS identified by minigene assay causes infantile liver failure syndrome type 2

in Genetics of Common and Rare Diseases

Anna Hu
Jun Liang
Hongbo Liu
Jinghui Jiang
Fujing Xie
Xin Zhou
Xiaojia Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1722189

814 views

Original Research

Published on 07 Nov 2025

Precision genomic profiling in Gaucher disease: insights from atypical presentations

in Genetics of Common and Rare Diseases

Armaan Saith
Noor Ul Ain
Jiapeng Ruan
Maniya Kasaiyan
Dhanpat Jain
Gary Israel
Sameet Mehta
Nigel S. Bamford
Shiny Nair
Pramod K. Mistry

Frontiers in Genetics

doi 10.3389/fgene.2025.1553036

1,960 views

16,575 articles

articles

Building capability for clinician-led genomic change: insights from use and non-use of a theory-informed model for change

The genetic diversity and population structure of native horse breeds in Xinjiang, China

Correction: Drought adaptation index (DAI) based on BLUP as a selection approach for drought-resilient switchgrass germplasm

Correction: Integrative machine learning and Mendelian randomization identify causal laboratory biomarkers for coronary artery lesions in Kawasaki disease: a prospective study

CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation

Case Report: Compound heterozygous CEP152 c.3346-5T>C variant and chr15 deletion causing recurrent MCPH–SCKS in a Chinese pregnant woman across two consecutive pregnancies

Computational-experimental strategy identifies Co-upregulated biomarkers linking coronary heart disease and type 2 diabetes pathogenesis

Ocular surface health and disease: insight from single-cell RNA sequencing

Epigenetic landscape in lysosomal storage disorders: mechanisms and modulation

Germline activating sequence variations in RASopathy spectrum genes: genotype–phenotype correlation in a North Indian cohort

Genotyping strategies for single-step genomic predictions in a simulated sheep population under different scenarios of pedigree error types

Unveiling disulfidptosis-linked lncRNA signatures: insights into the immune microenvironment and drug responsiveness in oral squamous cell carcinoma

Construction of a HSC activation-related lncRNA–miRNA–mRNA ceRNA regulatory network reveals potential molecules involved in liver fibrosis

Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) leaves

Advances in post-processing methods for multiple sequence alignment

KSRV: a Kernel PCA-Based framework for inferring spatial RNA velocity at single-cell resolution

Mechanistic insights into NFIX frameshift mutations in Malan syndrome: proteasomal degradation-mediated haploinsufficiency

Correction: Identification of shared diagnostic genes between osteoporosis and Crohn’s disease through integrated transcriptomic analysis and machine learning

Case Report: Whole-exome sequencing revealed a de novo variant in SETBP1 gene in a Chinese family with developmental delay

BRMS1L promotes chemotherapy sensitivity by inhibiting autophagy in breast cancer

Identifying gene-environment interactions across genome-wide, twin, and polygenic risk score approaches

ST8SIA6-AS1 serves as a prognostic biomarker in cancer and exhibits oncogenic properties in prostate cancer

Correction: A novel splicing variant in NBAS identified by minigene assay causes infantile liver failure syndrome type 2

Precision genomic profiling in Gaucher disease: insights from atypical presentations