Frontiers in Genetics

Original Research

Published on 26 Sep 2025

Developing prognostic models for cholesterol-related genes linked with immune infiltration in prostate cancer

in Cancer Genetics and Oncogenomics

Jie Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1604113

2,537 views

Original Research

Published on 25 Sep 2025

Association between LRRK2 gene polymorphisms and Parkinson’s disease progression in a Chinese Han population

in Genetics of Common and Rare Diseases

Zhaoting Zhang
Lei Geng
Jiuxin Gao
Ruifang She
Zhonglin Ge
Jianhua Liu
Qianqian He
Bing Fu
Weiguo Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1662348

2,287 views

Original Research

Published on 25 Sep 2025

Functional analysis of MEIS2 splice site variant c.438 + 1G>T in a congenital heart patient

in Genetics of Common and Rare Diseases

Chenyu Xu
Junjuan Li
Xinghui Ma
Wenqi Li
Bo Jiang
Hua Bai
Fuhong Wu
Chunlian Liu
Jiwei Gu

Frontiers in Genetics

doi 10.3389/fgene.2025.1629159

1,846 views

Original Research

Published on 25 Sep 2025

Cross-modal predictive modeling of multi-omic data in 3D airway organ tissue equivalents during viral infection

in Computational Genomics

Mostafa Rezapour
Patrick M. McNutt
David A. Ornelles
Stephen J. Walker
Sean V. Murphy
Anthony Atala
Metin Nafi Gurcan

Frontiers in Genetics

doi 10.3389/fgene.2025.1658577

2,772 views

Original Research

Published on 25 Sep 2025

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B57:01 and HLA-B58:01 typing: a comparative study

in Pharmacogenetics and Pharmacogenomics

Nattapong Intharuangrung
Chonticha Sirikul
Pattaraporn Nimsamer
Thidathip Wongsurawat
Auttachai Saejia
Nampeung Anukul

Frontiers in Genetics

doi 10.3389/fgene.2025.1649990

4,253 views

Original Research

Published on 25 Sep 2025

MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma

in Cancer Genetics and Oncogenomics

Rong Qi
Chen Fang
Penghui Liu
Weiguo Gu
Chao Shi
Guohua Zhang
Feng Qiu

Frontiers in Genetics

doi 10.3389/fgene.2025.1615018

2,308 views

Original Research

Published on 24 Sep 2025

Identifying metabolism-related genes in liver cancer through weighted gene co-expression network analysis and machine learning

in Cancer Genetics and Oncogenomics

Taorui Wang
Zijun Lai
Shengjun Tang
Lehang Lin
Mingjiao Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1654459

3,857 views

Original Research

Published on 24 Sep 2025

Intrauterine phenotype, genetic analysis, and pregnancy follow-up of fetuses with the 16p12.2 microdeletion

in Genetics of Common and Rare Diseases

Meiying Cai
Na Lin
Hailong Huang
Wenqiang You
Nan Guo
Liangpu Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1595399

1,767 views

Review

Published on 24 Sep 2025

Mechanisms of circular RNAs in diabetic cardiomyopathy: biological characteristics and clinical prospects

in RNA

Yunfei Guan
Quancheng Han
Meng Wang
Jianguo Xu
Xiujuan Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1665571

3,113 views
1 citation

Case Report

Published on 23 Sep 2025

Case Report: a family report of hereditary pancreatitis caused by SPINK1 and PRSS1 gene mutations

in Genetics of Common and Rare Diseases

Jing Xu
Ying Hu
Banghui Xiao
Juan He
Miao Zhang
Rui Wang
Nianchun Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1610108

2,506 views

Original Research

Published on 22 Sep 2025

Constructing a novel mitochondrial-related gene signature for predicting survival and evaluating the tumor immune microenvironment in clear cell renal cell carcinoma

in Cancer Genetics and Oncogenomics

Jiaxuan Qin
Lijian Zhang
Bowen Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1543593

3,950 views

Original Research

Published on 22 Sep 2025

Identification of platelet function-related genes in STEMI patients

in Computational Genomics

Jingjing Zhu
Shuangya Yang
Qing Guo
Yifan Yang
Bei Shi

Frontiers in Genetics

doi 10.3389/fgene.2025.1651794

1,739 views

Hypothesis and Theory

Published on 22 Sep 2025

Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation

in Evolutionary and Population Genetics

Todor Chobanov
Svetoslav Stamov
for Bulgarian Academy of Science and Institute for Balkan Studies

Frontiers in Genetics

doi 10.3389/fgene.2025.1610942

9,051 views

Original Research

Published on 22 Sep 2025

Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer

in Cancer Genetics and Oncogenomics

Xiucheng Jiang
Lan Shi
Mei Zhao
Cui Chen
Tao Tang
Simeng Ji
Bingbing Lv
Lihua Jia
Shuhan Duan
Jinyue Ma

Frontiers in Genetics

doi 10.3389/fgene.2025.1643229

2,105 views

Original Research

Published on 19 Sep 2025

The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC

in Cancer Genetics and Oncogenomics

Tianhe Ling
Jiahui Wu
Ling Xiaohao

Frontiers in Genetics

doi 10.3389/fgene.2025.1606111

2,358 views

Original Research

Published on 19 Sep 2025

Deciphering the shared genetic structure between hip osteoarthritis and femoral neck bone mineral density

in Human and Medical Genomics

Jianguo Zhou
Junfu Na
Zongkun Jiang
Xiaoyan Dou
Shixuan Wang
Hongtao Li
Jian Kang

Frontiers in Genetics

doi 10.3389/fgene.2025.1597005

2,664 views

Original Research

Published on 19 Sep 2025

A hypergraph neural network for prioritizing Alzheimer’s disease risk genes

in Computational Genomics

Meng Ma
Chao Deng
Yan Liu
Qingqing Cao
Fang Liu
Yan Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1668200

1,693 views

Review

Published on 19 Sep 2025

Beyond single references: pangenome graphs and the future of genomic medicine

in Human and Medical Genomics

Denis M. Nyaga
Roan E. Zaied
Olin K. Silander
Michael A. Black
Justin M. O’Sullivan

Frontiers in Genetics

doi 10.3389/fgene.2025.1679660

4,389 views

Original Research

Published on 19 Sep 2025

A novel COL2A1 mutation in a Chinese family with predominantly ocular Stickler syndrome

in Genetics of Common and Rare Diseases

Yanyu Lin
Xin Liu
Shuxian Lin
Jiansheng Lin

Frontiers in Genetics

doi 10.3389/fgene.2025.1646923

1,745 views

Original Research

Published on 18 Sep 2025

Genome-wide association analysis of resistance to bacterial cold-water disease in an important rainbow trout aquaculture breeding population

in Livestock Genomics

Bruna Santana
Yniv Palti
Guangtu Gao
Vibha Tripathi
Kyle E. Martin
Breno O. Fragomeni

Frontiers in Genetics

doi 10.3389/fgene.2025.1582138

2,184 views

Original Research

Published on 18 Sep 2025

Identification of prognostic and cellular senescence gene E2F1 of papillary thyroid carcinoma through bioinformatics analyses and experimental verification

in Cancer Genetics and Oncogenomics

Bin Yu
Shu-Yan Zhao
Yun-Hua Zhu
Jun-Jie Luo
Ke Zheng
Bin-Jie Shen
Yi-Lin Shen
Huan-Xin Zhong

Frontiers in Genetics

doi 10.3389/fgene.2025.1605385

2,155 views

Original Research

Accepted on 17 Sep 2025

Chloroplast Genomic Diversity in eleven Pennisetum Species

in Genomics of Plants and the Phytoecosystem

He Muhan
Qi Wang
Yuwen Zhang
Chunjuan Shi

Frontiers in Genetics

1,305 views

Original Research

Published on 17 Sep 2025

Panoramic analysis of the biological function and clinical value of SLC38A2 in human cancers: a study based on pan-cancer and single-cell analysis

in Cancer Genetics and Oncogenomics

Mao Liao
Yuqing Rao
Molan Li
Jiayang Guo
Kun Guo
Kaiyue Li
Rui Zheng
Yifan Liu
Qianyi Wang
Manni Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1658299

2,440 views

Original Research

Published on 17 Sep 2025

Uncovering differential gene expression between mtRNA-positive and -negative osteosarcoma cells: implications beyond mitochondrial function

in Computational Genomics

Xiaoyuan Meng
Zhongcheng Han
Wuerkan Yeerken
Zhigang Wang
Le Ma
Hongbo Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1588581

1,757 views

16,446 articles

articles

Developing prognostic models for cholesterol-related genes linked with immune infiltration in prostate cancer

Association between LRRK2 gene polymorphisms and Parkinson’s disease progression in a Chinese Han population

Functional analysis of MEIS2 splice site variant c.438 + 1G>T in a congenital heart patient

Cross-modal predictive modeling of multi-omic data in 3D airway organ tissue equivalents during viral infection

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B57:01 and HLA-B58:01 typing: a comparative study

MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma

Identifying metabolism-related genes in liver cancer through weighted gene co-expression network analysis and machine learning

Intrauterine phenotype, genetic analysis, and pregnancy follow-up of fetuses with the 16p12.2 microdeletion

Mechanisms of circular RNAs in diabetic cardiomyopathy: biological characteristics and clinical prospects

Case Report: a family report of hereditary pancreatitis caused by SPINK1 and PRSS1 gene mutations

Constructing a novel mitochondrial-related gene signature for predicting survival and evaluating the tumor immune microenvironment in clear cell renal cell carcinoma

Identification of platelet function-related genes in STEMI patients

Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation

Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer

The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC

Deciphering the shared genetic structure between hip osteoarthritis and femoral neck bone mineral density

A hypergraph neural network for prioritizing Alzheimer’s disease risk genes

Beyond single references: pangenome graphs and the future of genomic medicine

A novel COL2A1 mutation in a Chinese family with predominantly ocular Stickler syndrome

Genome-wide association analysis of resistance to bacterial cold-water disease in an important rainbow trout aquaculture breeding population

Identification of prognostic and cellular senescence gene E2F1 of papillary thyroid carcinoma through bioinformatics analyses and experimental verification

Chloroplast Genomic Diversity in eleven Pennisetum Species

Panoramic analysis of the biological function and clinical value of SLC38A2 in human cancers: a study based on pan-cancer and single-cell analysis

Uncovering differential gene expression between mtRNA-positive and -negative osteosarcoma cells: implications beyond mitochondrial function

articles

Developing prognostic models for cholesterol-related genes linked with immune infiltration in prostate cancer

Association between LRRK2 gene polymorphisms and Parkinson’s disease progression in a Chinese Han population

Functional analysis of MEIS2 splice site variant c.438 + 1G>T in a congenital heart patient

Cross-modal predictive modeling of multi-omic data in 3D airway organ tissue equivalents during viral infection

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B*57:01 and HLA-B*58:01 typing: a comparative study

MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma

Identifying metabolism-related genes in liver cancer through weighted gene co-expression network analysis and machine learning

Intrauterine phenotype, genetic analysis, and pregnancy follow-up of fetuses with the 16p12.2 microdeletion

Mechanisms of circular RNAs in diabetic cardiomyopathy: biological characteristics and clinical prospects

Case Report: a family report of hereditary pancreatitis caused by SPINK1 and PRSS1 gene mutations

Constructing a novel mitochondrial-related gene signature for predicting survival and evaluating the tumor immune microenvironment in clear cell renal cell carcinoma

Identification of platelet function-related genes in STEMI patients

Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation

Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer

The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC

Deciphering the shared genetic structure between hip osteoarthritis and femoral neck bone mineral density

A hypergraph neural network for prioritizing Alzheimer’s disease risk genes

Beyond single references: pangenome graphs and the future of genomic medicine

A novel COL2A1 mutation in a Chinese family with predominantly ocular Stickler syndrome

Genome-wide association analysis of resistance to bacterial cold-water disease in an important rainbow trout aquaculture breeding population

Identification of prognostic and cellular senescence gene E2F1 of papillary thyroid carcinoma through bioinformatics analyses and experimental verification

Chloroplast Genomic Diversity in eleven Pennisetum Species

Panoramic analysis of the biological function and clinical value of SLC38A2 in human cancers: a study based on pan-cancer and single-cell analysis

Uncovering differential gene expression between mtRNA-positive and -negative osteosarcoma cells: implications beyond mitochondrial function

Concordance of an in-house 2-steps PCR-SSP and nanopore sequencing for HLA-B57:01 and HLA-B58:01 typing: a comparative study