Frontiers in Genetics

Original Research

Published on 29 Oct 2025

LDLRAD4 is a potential diagnostic and prognostic biomarker correlated with immune infiltration in myelodysplastic syndromes

in Cytogenomics

Mengjie Xu
Shihao Wu
Kaixiang Zhang
Lirong Nie
Qinghua Li
Jihong Zhong
Yuming Zhang
Honghua He

Frontiers in Genetics

doi 10.3389/fgene.2025.1540161

1,713 views

Original Research

Published on 28 Oct 2025

Comparative RNA-seq and functional assays identify L-arginine transporter SLC7A2 as a potential regulator of osteogenesis in maxillary sinus mucosal stem cells

in Stem Cell Research

Jing Ren
Ningbo Geng
Tianren Zhou
Shiting Mo
Chi Zhang
Wei Peng
Chunhui Liao
Songling Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1701001

2,007 views

Review

Published on 28 Oct 2025

From bench to bytes: a practical guide to RNA sequencing data analysis

in Computational Genomics

Prabin Dawadi
Bivek Pokharel
Anita Shrestha
Dikshya Niraula
Afifa Naeem
Sayaka Miura
Mishal Roy
Saroj Nepal

Frontiers in Genetics

doi 10.3389/fgene.2025.1697922

5,344 views

Data Report

Published on 28 Oct 2025

De novo assembly and functional annotation of Henbit (Lamium amplexicaule) transcriptome

in Genomics of Plants and the Phytoecosystem

Young Ji Choi
Hyojung Son
Jaewon Lim
Siyoon Jeong
Seongmin Oh
Bomi Nam
Kang-Yeol Yu
Kyung Min Choi
Myunghee Jung
Ha Yeun Song

Frontiers in Genetics

doi 10.3389/fgene.2025.1612607

2,878 views

Review

Published on 28 Oct 2025

Computational models for pan-cancer classification based on multi-omics data

in Cancer Genetics and Oncogenomics

Jianlin Wang
Jiao Zhang
Xuebing Dai
Chaokun Yan
Caili Fang

Frontiers in Genetics

doi 10.3389/fgene.2025.1667325

3,137 views
1 citation

Review

Published on 28 Oct 2025

Gene therapy for disorders of sex development: current applications and future challenges

in Genetics of Common and Rare Diseases

Wenyuan Peng
Qian Zhao
Jiali Chen
Huifang Peng
Hongwei Jiang

Frontiers in Genetics

doi 10.3389/fgene.2025.1661127

3,720 views

Original Research

Published on 27 Oct 2025

Identification and functional analysis of a novel CSNK2A1 frameshift variant in stillbirth

in Statistical Genetics and Methodology

Nannan Zhang
Miao Han
Tong Zhao
Xinxin Tang
Zhiwei Wang
Yunqiu Du
Leilei Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1692704

1,831 views

Case Report

Published on 27 Oct 2025

Prenatal diagnosis of a de novo pathogenic HNRNPK variant in a Chinese fetus with abnormal ultrasound soft markers: a case report

in Human and Medical Genomics

Yuying Zhu
Zhen Yang
Qiumin Zhu
Ke Wu
Junying He
Hongmei Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1661743

1,805 views

Original Research

Published on 27 Oct 2025

Identification of druggable targets in melanoma by multi-omics Mendelian randomization integrated with transcriptomic and spatial analysis

in Applied Genetic Epidemiology

Jiahua Xing
Mingyong Yang
Muzi Chen
Ran Tao

Frontiers in Genetics

doi 10.3389/fgene.2025.1657356

1,890 views

Correction

Published on 27 Oct 2025

Correction: Effectiveness of non-invasive chromosomal screening for normal karyotype and chromosomal rearrangements

in ELSI in Science and Genetics

Bo-Lan Sun
Yong Wang
Sixi Wen
Liang Zhou
Chun-Hui Zhang
Ze-Xuan Wu
Jie Qiao
Qing-Yuan Sun
Ya-Xin Yao
Jing Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1711906

1,297 views

Correction

Published on 24 Oct 2025

Correction: Genome-wide association study of drought tolerance traits in sugar beet germplasms at the seedling stage

in Genomics of Plants and the Phytoecosystem

Wangsheng Li
Ming Lin
Jiajia Li
Dali Liu
Wenbo Tan
Xilong Yin
Yan Zhai
Yuanhang Zhou
Wang Xing

Frontiers in Genetics

doi 10.3389/fgene.2025.1685028

902 views

Case Report

Published on 24 Oct 2025

Case Report: Adenylosuccinate lyase deficiency type I caused by splicing disruption due to a novel missense variant in the ADSL gene

in Human and Medical Genomics

Artem Borovikov
Ksenia Davydenko
Aysylu Murtazina
Artem Sharkov
Ilya Kanivets
Alexandra Filatova
Mikhail Skoblov

Frontiers in Genetics

doi 10.3389/fgene.2025.1670299

1,742 views

Review

Published on 24 Oct 2025

Advances in RNA-based therapeutics: current breakthroughs, clinical translation, and future perspectives

in RNA

Sarbjeet Kaur Makkar

Frontiers in Genetics

doi 10.3389/fgene.2025.1675209

19,418 views
2 citations

Original Research

Published on 23 Oct 2025

Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia

in Computational Genomics

Yu Zhou
Shuang Zhang
Yao-Xia Liu
Xin Dai
Ting Zhang
Xiao-Tao Xu
Sheng-Nan Deng
Min-Yan Yang
Zhen Fan

Frontiers in Genetics

doi 10.3389/fgene.2025.1690947

2,126 views

Original Research

Published on 23 Oct 2025

Non-polar components in PM2.5 increase matrix remodeling of CRS by up-regulating CEMIP in nasal fibroblasts

in Predictive Toxicology and Exposomics

Jiayao Zhou
Ying Zhu
Huilin Hu
Ru Tang
Shiyao Zhang
Yuelong Gu
Song Mao
Shilei Pu
Hai Lin
Yue Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1672729

2,123 views

Review

Published on 23 Oct 2025

Single-cell transcriptomics in metastatic breast cancer: mapping tumor evolution and therapeutic resistance

in Cancer Genetics and Oncogenomics

Xu Han
Xin Li
Ling Bai
Gangling Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1669741

3,881 views

Case Report

Published on 23 Oct 2025

Case Report: a novel missense variant of FGD5 in a family with tetralogy of Fallot

in Genetics of Common and Rare Diseases

Meng-Wei Liu
Yi Dong
Rong Xiang
Liping Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1663959

2,017 views

Original Research

Published on 23 Oct 2025

aiGeneR 3.0: an enhanced deep network model for resistant strain identification and multi-drug resistance prediction in Escherichia coli causing urinary tract infection using next-generation sequencing data

in Pharmacogenetics and Pharmacogenomics

Debasish Swapnesh Kumar Nayak
Abhilash Pati
Amrutanshu Panigrahi
Mudassir Khan
Bayan Alabdullah
Santanu Kumar Sahoo
Bibhuprasad Sahu
Abrar Almjally
Saurav Mallik
Tripti Swarnkar

Frontiers in Genetics

doi 10.3389/fgene.2025.1651917

2,323 views

Original Research

Published on 23 Oct 2025

A newly discovered Lnc-PDZD7-3 increased metastatic and proliferative potential of lung adenocarcinoma cells via modulating FN1/fibronectin signaling

in Cancer Genetics and Oncogenomics

Guodong Zhang
Jianbo Zhang
Fachang Yu
Xiaohe Hao

Frontiers in Genetics

doi 10.3389/fgene.2025.1618449

1,492 views
1 citation

Correction

Published on 23 Oct 2025

Correction: Heat shock protein 27 phosphorylation state is associated with cancer progression

in Systems Biology Archive

Maria Katsogiannou
Claudia Andrieu
Palma Rocchi

Frontiers in Genetics

doi 10.3389/fgene.2025.1703072

997 views

Original Research

Published on 22 Oct 2025

A novel frameshift variant of PAX3 in a Chinese Yugur family with Waardenburg syndrome type 1

in Genetics of Common and Rare Diseases

Lupeng Zhan
Baicheng Xu
Dujuan Lin
Ya Wang
Panpan Bian

Frontiers in Genetics

doi 10.3389/fgene.2025.1679351

1,673 views

Original Research

Published on 22 Oct 2025

S100A10 knockdown exacerbates phenylephrine-induced cardiomyocyte hypertrophy via modulating mitochondrial oxidative phosphorylation

in Cytogenomics

Feixue Xu
Yajie Chen
Man Xu
Dan Li
Yinshan Lu
Meng Zhang
Jiahao Li
Wanyi Li
Yingying Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1610008

1,895 views
1 citation

Editorial

Published on 22 Oct 2025

Editorial: Decoding complexity: genomic, epigenomic, and environmental dynamics in developmental and neurogenetic disorders

in Epigenomics and Epigenetics

Alessandro Fiorenzano
Luísa Azevedo

Frontiers in Genetics

doi 10.3389/fgene.2025.1724013

1,451 views

Case Report

Published on 21 Oct 2025

Case Report: Clinical and molecular features of a radiosensitive autoimmune polyendocrine syndrome type 1 patient with oral carcinoma

in Genetics of Common and Rare Diseases

Asma Chikhaoui
Houda Hammami-Ghorbel
Dorra Najjar
Semia Zarraa
Safia Yahiaoui
Davor Lessel
Houda Yacoub-Youssef

Frontiers in Genetics

doi 10.3389/fgene.2025.1588108

2,171 views

16,584 articles

articles

LDLRAD4 is a potential diagnostic and prognostic biomarker correlated with immune infiltration in myelodysplastic syndromes

Comparative RNA-seq and functional assays identify L-arginine transporter SLC7A2 as a potential regulator of osteogenesis in maxillary sinus mucosal stem cells

From bench to bytes: a practical guide to RNA sequencing data analysis

De novo assembly and functional annotation of Henbit (Lamium amplexicaule) transcriptome

Computational models for pan-cancer classification based on multi-omics data

Gene therapy for disorders of sex development: current applications and future challenges

Identification and functional analysis of a novel CSNK2A1 frameshift variant in stillbirth

Prenatal diagnosis of a de novo pathogenic HNRNPK variant in a Chinese fetus with abnormal ultrasound soft markers: a case report

Identification of druggable targets in melanoma by multi-omics Mendelian randomization integrated with transcriptomic and spatial analysis

Correction: Effectiveness of non-invasive chromosomal screening for normal karyotype and chromosomal rearrangements

Correction: Genome-wide association study of drought tolerance traits in sugar beet germplasms at the seedling stage

Case Report: Adenylosuccinate lyase deficiency type I caused by splicing disruption due to a novel missense variant in the ADSL gene

Advances in RNA-based therapeutics: current breakthroughs, clinical translation, and future perspectives

Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia

Non-polar components in PM2.5 increase matrix remodeling of CRS by up-regulating CEMIP in nasal fibroblasts

Single-cell transcriptomics in metastatic breast cancer: mapping tumor evolution and therapeutic resistance

Case Report: a novel missense variant of FGD5 in a family with tetralogy of Fallot

aiGeneR 3.0: an enhanced deep network model for resistant strain identification and multi-drug resistance prediction in Escherichia coli causing urinary tract infection using next-generation sequencing data

A newly discovered Lnc-PDZD7-3 increased metastatic and proliferative potential of lung adenocarcinoma cells via modulating FN1/fibronectin signaling

Correction: Heat shock protein 27 phosphorylation state is associated with cancer progression

A novel frameshift variant of PAX3 in a Chinese Yugur family with Waardenburg syndrome type 1

S100A10 knockdown exacerbates phenylephrine-induced cardiomyocyte hypertrophy via modulating mitochondrial oxidative phosphorylation

Editorial: Decoding complexity: genomic, epigenomic, and environmental dynamics in developmental and neurogenetic disorders

Case Report: Clinical and molecular features of a radiosensitive autoimmune polyendocrine syndrome type 1 patient with oral carcinoma