Frontiers in Genetics

Original Research

Published on 05 Sep 2025

Integrative analysis of single-cell and microarray data reveals SPI1-centered macrophage regulatory signatures in ulcerative colitis

in Computational Genomics

Yeqing Yu
Chengwei Yu
Shanshan Dai
Yixu Liu
Lanlan Hu
Weimin Lu

Frontiers in Genetics

doi 10.3389/fgene.2025.1617834

3,351 views

Original Research

Published on 05 Sep 2025

Geographical distribution of ALDH2 rs671 polymorphism in Chinese angina pectoris patients

in Genetics of Common and Rare Diseases

Wenjia Dong
Junjie Yu
Siqi Xu
Hongsheng Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1543963

2,287 views

Original Research

Published on 05 Sep 2025

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

in Cancer Genetics and Oncogenomics

Pengpeng Gui
Zhengyi Han
Zhenyu Yin
Peng Cao
Xin Zhou
Yan Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1593314

2,987 views

Original Research

Published on 05 Sep 2025

Temporal regulation of genetic programs governing multiple cell death during myocardial ischemia-reperfusion injury

in Genetics of Common and Rare Diseases

Qiuyu Pang
Xiangmin Meng
Zhenfang Zhou
Lu You
Jinghan Yuan
Qipu Feng
Bingmei Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1632867

2,636 views
2 citations

Original Research

Published on 03 Sep 2025

3D-cultured hADSCs-derived exosomes deliver circ_0011129 to synergistically attenuate skin photoaging

in Genetics of Aging

Yu Zhang
Feng Zhou
Gang Nie
Liang Li
Juan Wen
Shimin He
Amin Yao

Frontiers in Genetics

doi 10.3389/fgene.2025.1627472

3,781 views

Original Research

Published on 03 Sep 2025

Integrating BERT pre-training with graph common neighbours for predicting ceRNA interactions

in RNA

Zhengxing Xie
Tianping Ying
Ge Jing
Shiyang Liang
Junhua Liu
Lianghua Tang

Frontiers in Genetics

doi 10.3389/fgene.2025.1606016

1,896 views

Original Research

Published on 03 Sep 2025

Validation of a genome-wide polygenic score for body mass index in South Asians

in Genetics of Common and Rare Diseases

Ramesh Menon
Nikhat Khan
Sandeep Charugulla
Akshi Bassi
Pooja Dangare
Akshay Dedaniya
Aakanksha Pant
Rammurthy Anjanappa
Praveena L. Samson
Uthra Satagopan

Frontiers in Genetics

doi 10.3389/fgene.2025.1603542

2,436 views

Perspective

Published on 03 Sep 2025

From reading to writing genomes: a new direction in ELSI

in ELSI in Science and Genetics

Koichi Mikami

Frontiers in Genetics

doi 10.3389/fgene.2025.1667769

3,172 views

Original Research

Published on 03 Sep 2025

Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

in Computational Genomics

Ning Zhang
Ye Zhang
Rui-Fei Yang
Min Tan
Hai-Qing Chu
Abdur Rehman
Lu-Yu Yang
Ya-Yu Li
Fahad M. Alshabrmi
Xin Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1614254

4,456 views
2 citations

Data Report

Published on 01 Sep 2025

Data report: transcriptome profiling of 13 tissues of Junmu No. 1 boars

in RNA

Chunyan Bai
Jiayi Ning
Junwen Fei
Zhenbo Wang
Yu He
Jing Li
Xiaoran Zhang
Shuang Liang
Dali Wang
Hao Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1641395

2,358 views

Original Research

Published on 01 Sep 2025

A de novo mutation in RAB11A is associated with neurodevelopmental disorder accompanied by variable multisystem abnormalities

in Genetics of Common and Rare Diseases

Huiting Zhang
Jingtao Zhang
Xue Ma
Zhehui Chen
Ying Jin
Mengqiu Li
Hui Dong
Feng Gu
Yao Zhang
Yanling Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1636206

2,210 views

Original Research

Published on 01 Sep 2025

Mining for gene-environment and gene-gene interactions: parametric and non-parametric tests for detecting variance quantitative trait loci

in Statistical Genetics and Methodology

Wan-Yu Lin

Frontiers in Genetics

doi 10.3389/fgene.2025.1617504

2,886 views

Editorial

Published on 01 Sep 2025

Editorial: Mitochondria in metabolic reprogramming and immune activation: the key gene and therapeutic target

in Immunogenetics

Yongzheng Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1686852

2,882 views

Original Research

Published on 29 Aug 2025

Comparative analysis of blood whole transcriptome profiles in Yili horses pre- and post-5000-meter racing

in Livestock Genomics

Yi Su
Wanlu Ren
Shikun Ma
Jun Meng
Xinkui Yao
Yaqi Zeng
Zexu Li
Luling Li
Ran Wang
Jianwen Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1651628

4,320 views
1 citation

Original Research

Published on 29 Aug 2025

Identification and experimental validation of circular RNA-associated ceRNA networks in intrauterine adhesion

in RNA

Yajie Chang
Rui Xiang
Qi Guo
Jing Li
Xiaolan Li
Zhi Zeng
Jintao Peng
Xiaoyan Liang

Frontiers in Genetics

doi 10.3389/fgene.2025.1619698

2,345 views

Brief Research Report

Published on 29 Aug 2025

Identification of oncofetal PIWI-interacting RNAs as potential prognostic biomarkers in non-small cell lung cancer

in Cancer Genetics and Oncogenomics

Michelle E. Pewarchuk
Vanessa G. P. Souza
David E. Cohn
Nikita Telkar
Greg L. Stewart
Katya H. Bénard
Patricia P. Reis
Victor D. Martinez
Wendy P. Robinson
Wan L. Lam

Frontiers in Genetics

doi 10.3389/fgene.2025.1611805

2,240 views
1 citation

Original Research

Published on 29 Aug 2025

Affective phenotypes in heterozygous LRRK2 R1441G knock-in mice

in Neurogenomics

Marcus H. F. Ng
Jimmy W. Y. Lam
Zoe Y. K. Choi
Hui-Fang Liu
Philip W. L. Ho
Benson W. M. Lau
Benjamin K. Yee

Frontiers in Genetics

doi 10.3389/fgene.2025.1629897

4,044 views

Mini Review

Published on 29 Aug 2025

Mesenchymal stem cells and exosomes in ischemic brain injury: a review

in Stem Cell Research

Haiyan Xu
Lanlan Yang
Weitie Wang
Chengwei Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1639756

4,631 views
2 citations

Original Research

Published on 29 Aug 2025

Targeted exome sequencing for molecular diagnosis of pediatric Alport syndrome in Southwest China

in Genetics of Common and Rare Diseases

Cong Zhou
Yuanyuan Xiao
Xing Wei
Jing Wang
Shanling Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1580864

1,899 views

Original Research

Published on 29 Aug 2025

The first complete mitochondrial genome of Biotodoma cupido (Cichiliformes: Cichlidae) and its phylogeny

in Livestock Genomics

Xiaoli Zhang
Shuang-Xi Jia
Cheng-He Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1623517

2,612 views
1 citation

Brief Research Report

Published on 29 Aug 2025

Codon usage bias analysis of the WRKY gene family in Musa acuminata

in Genomics of Plants and the Phytoecosystem

Jiaman Sun
Ji Zhang
Jinzhong Zhang
Brett J. Ferguson
Andrew Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1647037

2,511 views

Correction

Published on 29 Aug 2025

Correction: Engineering novel features for diabetes complication prediction using synthetic electronic health records

in Computational Genomics

Daniel Voskergian
Burcu Bakir-Gungor
Malik Yousef

Frontiers in Genetics

doi 10.3389/fgene.2025.1687832

1,221 views

Original Research

Published on 28 Aug 2025

Identification and validation of a histone modification-related gene signature to predict the prognosis of multiple myeloma

in Cancer Genetics and Oncogenomics

Juan Lyu
Shanmei Lyu
Ying Qian
Yi Feng
Zhuan Zheng
Lihong Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1613631

2,393 views

Editorial

Published on 28 Aug 2025

Editorial: Emerging relevance of molecular profiling in global cancer research and management

in Cancer Genetics and Oncogenomics

Premila Leiphrakpam
Srijan Shukla
Chandrakanth Are

Frontiers in Genetics

doi 10.3389/fgene.2025.1679501

1,755 views

16,587 articles

articles

Integrative analysis of single-cell and microarray data reveals SPI1-centered macrophage regulatory signatures in ulcerative colitis

Geographical distribution of ALDH2 rs671 polymorphism in Chinese angina pectoris patients

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

Temporal regulation of genetic programs governing multiple cell death during myocardial ischemia-reperfusion injury

3D-cultured hADSCs-derived exosomes deliver circ_0011129 to synergistically attenuate skin photoaging

Integrating BERT pre-training with graph common neighbours for predicting ceRNA interactions

Validation of a genome-wide polygenic score for body mass index in South Asians

From reading to writing genomes: a new direction in ELSI

Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

Data report: transcriptome profiling of 13 tissues of Junmu No. 1 boars

A de novo mutation in RAB11A is associated with neurodevelopmental disorder accompanied by variable multisystem abnormalities

Mining for gene-environment and gene-gene interactions: parametric and non-parametric tests for detecting variance quantitative trait loci

Editorial: Mitochondria in metabolic reprogramming and immune activation: the key gene and therapeutic target

Comparative analysis of blood whole transcriptome profiles in Yili horses pre- and post-5000-meter racing

Identification and experimental validation of circular RNA-associated ceRNA networks in intrauterine adhesion

Identification of oncofetal PIWI-interacting RNAs as potential prognostic biomarkers in non-small cell lung cancer

Affective phenotypes in heterozygous LRRK2 R1441G knock-in mice

Mesenchymal stem cells and exosomes in ischemic brain injury: a review

Targeted exome sequencing for molecular diagnosis of pediatric Alport syndrome in Southwest China

The first complete mitochondrial genome of Biotodoma cupido (Cichiliformes: Cichlidae) and its phylogeny

Codon usage bias analysis of the WRKY gene family in Musa acuminata

Correction: Engineering novel features for diabetes complication prediction using synthetic electronic health records

Identification and validation of a histone modification-related gene signature to predict the prognosis of multiple myeloma

Editorial: Emerging relevance of molecular profiling in global cancer research and management