Frontiers in Genetics

Original Research

Published on 07 Jul 2025

Identification of a novel microdeletion at 9q21.13 in a family with epilepsy, intellectual disability, and speech disorders and literature review

in Genetics of Common and Rare Diseases

Liqing Jiang
Jiaqi Li
Aizhong Han
Fei Hou
Xiaotong Wei
Yanjun Tian

Frontiers in Genetics

doi 10.3389/fgene.2025.1616005

1,929 views

Original Research

Published on 07 Jul 2025

A novel vasculogenic mimicry-related nomogram predicts prognosis in hepatocellular carcinoma

in Cancer Genetics and Oncogenomics

Yun Zhong
Fadian Ding
Han Zhang
Denghan Zhang
Xiang Zhang
Shangeng Weng

Frontiers in Genetics

doi 10.3389/fgene.2025.1431624

2,446 views

Original Research

Published on 07 Jul 2025

Geometry-enhanced graph neural networks accelerate circRNA therapeutic target discovery

in Computational Genomics

Zhen Li
Mingming Qi
Juyuan Huang
Wei Zhang
Xu Tan
Yifan Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1633391

1,728 views

Original Research

Published on 07 Jul 2025

Integrating genome and transcriptome analysis to decipher balanced structural variants in unsolved cases of neurodevelopmental disorders

in Genetics of Common and Rare Diseases

Simona Mellone
Alice Spano
Denise Vurchio
Giulia Borgonovi
Alessandro Ugonotti
Giulia Paglino
Alba Bianco
Sara Ronzani
Maurizio Sciancalepore
Flavia Prodam

Frontiers in Genetics

doi 10.3389/fgene.2025.1603513

1,921 views

Original Research

Published on 07 Jul 2025

Identification and validation of DNA methylation-driven gene OSR1 as a novel tumor suppressor for the diagnosis and prognosis of breast cancer

in Cancer Genetics and Oncogenomics

Jian Xu
Biao Yang
Ling Cheng
Chen Gan
Runze Huang
Anlong Li
Han Ge
Longyu Hu
Meiwen Ling
Xinyi Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1583620

2,500 views

Mini Review

Published on 04 Jul 2025

Application of AI in the identification of gastrointestinal stromal tumors: a comprehensive analysis based on pathological, radiological, and genetic variation features

in Cancer Genetics and Oncogenomics

Lei Zheng
Dan-Wen Jin
Hong-Wei Yu
Ze Yu
Li-Yong Qian

Frontiers in Genetics

doi 10.3389/fgene.2025.1555744

2,404 views

Case Report

Published on 04 Jul 2025

Case Report: The window that closed too soon: lessons from a late CLN2 diagnosis and death of a 9-year-old boy

in Neurogenomics

Anna Bryzik
Dawid Larysz
Patrycja Larysz
Julia Izabela Karpierz
Justyna Paprocka

Frontiers in Genetics

doi 10.3389/fgene.2025.1622185

3,124 views

Brief Research Report

Published on 04 Jul 2025

A novel missense variant of HS6ST2 gene in Paganini-Miozzo syndrome with a rare neurodevelopmental and Endocrine phenotypes

in Statistical Genetics and Methodology

Meiling Zhang
Xiao Chang
Xiaoyun Du
Zhen Chen
Xinyue Zhang
Fucheng Cai

Frontiers in Genetics

doi 10.3389/fgene.2025.1515260

1,538 views

Original Research

Published on 04 Jul 2025

The clinical and genetic profiles of spinal muscular atrophy with respiratory distress type 1 and identification of a novel mutation in IGHMBP2 in China

in Genetics of Common and Rare Diseases

Yanjun Wang
Ya Yang
Jingjing Wang
Qian Han
Nana Zhai
Shufang Xiao

Frontiers in Genetics

doi 10.3389/fgene.2025.1594265

1,648 views

Original Research

Published on 03 Jul 2025

Genome-wide association study and haplotype analyses reveal the genetic architecture of agronomic traits and sugars in sweet sorghum

in Genomics of Plants and the Phytoecosystem

Abdullah Bin Umar
Ajay Prasanth Ramalingam
Bushra Sadia
Faisal Saeed Awan
Farooq Ahmad Khan
Mariam Nasir
Amy Bernardo
Paul St. Amand
Guihua Bai
P. V. Vara Prasad

Frontiers in Genetics

doi 10.3389/fgene.2025.1611863

2,903 views

Case Report

Published on 03 Jul 2025

Case Report: Surgical management of primary lymphedema with a novel PROX1 mutation involving upper and lower limbs

in Genetics of Common and Rare Diseases

Junzhe Chen
Liangliang Wang
Xiangkui Wu
Bihua Wu
Hai Li
Shune Xiao
Chengliang Deng

Frontiers in Genetics

doi 10.3389/fgene.2025.1560471

1,891 views
1 citation

Original Research

Published on 03 Jul 2025

Analysis of microRNA expression reveals convergent evolution of the molecular control of diapause in annual killifishes

in Genetics of Aging

Emanuel Barth
Mario Baumgart
Luca Dolfi
Rongfeng Cui
Marco Groth
Roberto Ripa
Aurora Savino
Dario Riccardo Valenzano
Matthias Platzer
Manja Marz

Frontiers in Genetics

doi 10.3389/fgene.2025.1583989

2,481 views
1 citation

Brief Research Report

Published on 03 Jul 2025

Statistic tells: the regulatory pendulum of permit trajectories in China’s genetic governance (2021-2024)

in ELSI in Science and Genetics

Lingqiao Song
Zhenyu Liu
Fanlin Meng

Frontiers in Genetics

doi 10.3389/fgene.2025.1611003

2,606 views

Original Research

Published on 03 Jul 2025

Genome-wide association and functional annotation analyses reveal candidate genes and pathways associated with various ewe longevity indicators in U.S. Katahdin sheep

in Livestock Genomics

Luis F. B. Pinto
Ronald M. Lewis
Artur O. Rocha
Brad A. Freking
Tom W. Murphy
Carrie S. Wilson
Sara M. Nilson
Joan M. Burke
Luiz F. Brito

Frontiers in Genetics

doi 10.3389/fgene.2025.1600587

3,242 views
1 citation

Editorial

Published on 03 Jul 2025

Editorial: Multi-omics and molecular biology studies on abiotic stress in crops

in Genomics of Plants and the Phytoecosystem

Xiaobo Luo
Georgia Ntatsi
Rong Zhou
Mintao Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1607710

1,855 views

Review

Published on 02 Jul 2025

Get ready for short tandem repeats analysis using long reads-the challenges and the state of the art

in Genomic Assay Technology

Marija Chaushevska
Karmele Alapont-Celaya
Anne Kristine Schack
Lukasz Krych
M. Carmen Garrido Navas
Anastasia Krithara
Gjorgji Madjarov

Frontiers in Genetics

doi 10.3389/fgene.2025.1610026

4,237 views

Original Research

Published on 02 Jul 2025

Optimizing the single-step model for predicting fumonisins resistance in maize hybrids accounting for the genotype-by-environment interaction

in Genomics of Plants and the Phytoecosystem

Jeniffer Santana Pinto Coelho Evangelista
Kaio Olimpo das Graças Dias
Maria Marta Pastina
Saulo Chaves
Lauro José Moreira Guimarães
Jorge Hidalgo
Julian Garcia-Abadillo
Reyna Persa
Valéria Aparecida Vieira Queiroz
Dagma Dionísia da Silva

Frontiers in Genetics

doi 10.3389/fgene.2025.1475452

1,596 views

Original Research

Published on 02 Jul 2025

Bioinformatics analysis and experimental validation of ferroptosis genes in heart failure and atrial fibrillation

in Genetics of Common and Rare Diseases

Zhi Wang
Chi Yuan
Tao Xu
Weixing Xie
Jiehua Wu
Hegui Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1541342

3,084 views

Case Report

Published on 02 Jul 2025

Case Report: FBN1 mutation screening in South African patients with Marfan syndrome

in Human and Medical Genomics

F. Mhlongo
C. Feben
A. Krause
N. Carstens

Frontiers in Genetics

doi 10.3389/fgene.2025.1612411

1,863 views

Review

Published on 02 Jul 2025

Current progress and future perspective of super-enhancers: a viable and effective bridge between the transcriptional apparatus and disease

in Epigenomics and Epigenetics

Ran Wang
Aiying Li
Zongran Pang

Frontiers in Genetics

doi 10.3389/fgene.2025.1611905

3,663 views

Original Research

Published on 02 Jul 2025

Clinical validation of an integrated risk assessment test incorporating genomic and non-genomic data for sporadic breast cancer in Colombia

in Applied Genetic Epidemiology

Harvy Mauricio Velasco Parra
Danny Styvens Cardona
Cesar Augusto Buitrago
Melisa Naranjo Vanegas
Sebastián Gutiérrez Hincapié
Carolina Jaramillo Jaramillo
Alicia Maria Cock-Rada
Carolina Benavides Duque
Clara Patricia Piedrahita
Catalina Bustamante

Frontiers in Genetics

doi 10.3389/fgene.2025.1556907

2,771 views
1 citation

Original Research

Published on 02 Jul 2025

Exploration of biomarkers associated with histone lactylation modification in spinal cord injury

in Computational Genomics

Yisong Sun
Jie Gao
Juehua Jing

Frontiers in Genetics

doi 10.3389/fgene.2025.1609439

3,358 views

Editorial

Published on 02 Jul 2025

Editorial: Recent advances in genomics and oncogenomics for personalized medicine

in Cancer Genetics and Oncogenomics

Sulev Koks

Frontiers in Genetics

doi 10.3389/fgene.2025.1635341

1,903 views

Review

Published on 02 Jul 2025

Conceptualizing the public good for genomics in the global South: a cross-disciplinary roundtable dialogue

in ELSI in Science and Genetics

Tayyaba Jiwani
Adjua Akinwumi
Jocelyn Cheé-Santiago
Yulia Egorova
Gabriel Frassetto
Ricardo di Lazzaro Filho
Iscia Lopes-Cendes
Mercedes Okumura
José Antonio Alonso Pavón
Alice B. Popejoy

Frontiers in Genetics

doi 10.3389/fgene.2025.1523396

2,402 views

16,444 articles

articles

Identification of a novel microdeletion at 9q21.13 in a family with epilepsy, intellectual disability, and speech disorders and literature review

A novel vasculogenic mimicry-related nomogram predicts prognosis in hepatocellular carcinoma

Geometry-enhanced graph neural networks accelerate circRNA therapeutic target discovery

Integrating genome and transcriptome analysis to decipher balanced structural variants in unsolved cases of neurodevelopmental disorders

Identification and validation of DNA methylation-driven gene OSR1 as a novel tumor suppressor for the diagnosis and prognosis of breast cancer

Application of AI in the identification of gastrointestinal stromal tumors: a comprehensive analysis based on pathological, radiological, and genetic variation features

Case Report: The window that closed too soon: lessons from a late CLN2 diagnosis and death of a 9-year-old boy

A novel missense variant of HS6ST2 gene in Paganini-Miozzo syndrome with a rare neurodevelopmental and Endocrine phenotypes

The clinical and genetic profiles of spinal muscular atrophy with respiratory distress type 1 and identification of a novel mutation in IGHMBP2 in China

Genome-wide association study and haplotype analyses reveal the genetic architecture of agronomic traits and sugars in sweet sorghum

Case Report: Surgical management of primary lymphedema with a novel PROX1 mutation involving upper and lower limbs

Analysis of microRNA expression reveals convergent evolution of the molecular control of diapause in annual killifishes

Statistic tells: the regulatory pendulum of permit trajectories in China’s genetic governance (2021-2024)

Genome-wide association and functional annotation analyses reveal candidate genes and pathways associated with various ewe longevity indicators in U.S. Katahdin sheep

Editorial: Multi-omics and molecular biology studies on abiotic stress in crops

Get ready for short tandem repeats analysis using long reads-the challenges and the state of the art

Optimizing the single-step model for predicting fumonisins resistance in maize hybrids accounting for the genotype-by-environment interaction

Bioinformatics analysis and experimental validation of ferroptosis genes in heart failure and atrial fibrillation

Case Report: FBN1 mutation screening in South African patients with Marfan syndrome

Current progress and future perspective of super-enhancers: a viable and effective bridge between the transcriptional apparatus and disease

Clinical validation of an integrated risk assessment test incorporating genomic and non-genomic data for sporadic breast cancer in Colombia

Exploration of biomarkers associated with histone lactylation modification in spinal cord injury

Editorial: Recent advances in genomics and oncogenomics for personalized medicine

Conceptualizing the public good for genomics in the global South: a cross-disciplinary roundtable dialogue