Frontiers in Genetics

Original Research

Published on 18 Aug 2025

High-density SNP-based linkage map construction and QTL analysis for growth-related traits in Luciobarbus brachycephalus using whole-genome resequencing data

in Livestock Genomics

Xuanpeng Wang
Dandan Gao
Gaowei Zhang
Yongchun Ge
Xinhai Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1644874

2,240 views

Original Research

Published on 18 Aug 2025

Identification of anoikis-related genes to develop a risk model and predict the prognosis and tumor microenvironment in rectal adenocarcinoma

in Cancer Genetics and Oncogenomics

Bing Zhao
Xuegui Tang

Frontiers in Genetics

doi 10.3389/fgene.2025.1604541

2,139 views

Original Research

Published on 18 Aug 2025

The comparison of the prognostic value of different inflammation-related indicators in patients with oral squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Aoming Cheng
Kaixiong Wei
Qiaoshi Xu
Chong Wang
Bo Li
Huan Liu
Lirui Zhang
Hanchen Zhou
Yu Huang
Yiming Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1652603

2,295 views
1 citation

Original Research

Published on 18 Aug 2025

Bioinformatics analysis combined with untargeted metabolomics reveals lipid metabolism-related genes and their biological markers in chronic spontaneous urticaria

in Human and Medical Genomics

Zhiming Hu
Qiong Wang
Yuqi Wang
Yao Gao
Jianhua Hao
Rui Li
Hua Zhao
Shuping Guo
Hongzhou Cui

Frontiers in Genetics

doi 10.3389/fgene.2025.1550205

3,067 views

Original Research

Published on 18 Aug 2025

Four novel genetic mutations are associated with patent foramen ovale in Tibetan population using whole exome sequencing

in Genetics of Common and Rare Diseases

Hongwei Li
Yongjun He
Yong Wu
Lanxin Liu
Wei Du
Duika Wang
Zeng He
Liming Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1592306

2,606 views

Original Research

Published on 15 Aug 2025

A Benchmark of methods for SARS-CoV-2 whole genome sequencing and development of a more sensitive method

in Genomic Assay Technology

Anthony Bayega
Sarah J. Reiling
Ju Ling Liu
Isabelle Dubuc
Annie Gravel
Louis Flamand
Jiannis Ragoussis

Frontiers in Genetics

doi 10.3389/fgene.2025.1516791

3,901 views
1 citation

Original Research

Published on 15 Aug 2025

New therapeutic targets for endometriosis predicted through mendelian randomization analysis and case-control trials

in Applied Genetic Epidemiology

Linyao Zheng
Yue Yin
Xiaotong Wang
Baoju Wang
Ran Cui
Guangmei Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1631446

4,679 views

Original Research

Published on 15 Aug 2025

A retrospective analysis of 38,652 amniotic fluid karyotype

in Human and Medical Genomics

Jianyu Ren
Xiaojiao Guan
Wenzhe Lv
Yousheng Yan
Yanmei Si
Shufa Yang
Chenghong Yin

Frontiers in Genetics

doi 10.3389/fgene.2025.1655290

2,357 views
1 citation

Case Report

Published on 15 Aug 2025

A rare intronic c.2654+1G>A mutation in CSF1R-microglial encephalopathy: a case report

in Genetics of Common and Rare Diseases

HongYan Wu
JingYu Shi
XiaoShan Wang
Mei Yang
Jing Cai

Frontiers in Genetics

doi 10.3389/fgene.2025.1593964

2,001 views

Original Research

Published on 15 Aug 2025

Integrative machine learning and Mendelian randomization identify causal laboratory biomarkers for coronary artery lesions in Kawasaki disease: a prospective study

in Computational Genomics

Hancao Yang
Meng Wu
Keqing Liang
Yi Li
Ran Yang
Beibei Yuan
Ming Wu
Jin Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1646032

2,725 views

Original Research

Published on 14 Aug 2025

Genetic basis of phenotypic diversity in C. stenophylla: a stepping stone for climate-adapted coffee cultivar development

in Genomics of Plants and Plant-Associated Organisms

Paul M. Lahai
Peter O. Aikpokpodion
Alieu Mohamed Bah
Mohamed T. Lahai
Lyndel W. Meinhardt
Seunghyun Lim
Ezekiel Ahn
Dapeng Zhang
Sunchung Park

Frontiers in Genetics

doi 10.3389/fgene.2025.1554029

3,283 views
1 citation

Original Research

Published on 14 Aug 2025

Pseudohypoparathyroidism type 1B mimicking gitelman syndrome: diagnostic pitfalls and molecular insights

in Genetics of Common and Rare Diseases

Yiming Zhao
Lijun Mou
Oumayma Akaaboune
Jiudan Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1638472

2,156 views

Original Research

Published on 14 Aug 2025

Shared genetic architecture between grip strength and cognitive function: insights from large-scale genome-wide cross-trait analysis

in Genetics of Aging

Hong Liu
Gangqiang Wu
Jun Tan
Chunyun Yuan

Frontiers in Genetics

doi 10.3389/fgene.2025.1538308

3,082 views

Original Research

Published on 14 Aug 2025

The rare hemoglobin variants Hb O-Arab and Hb D-Punjab identified in population-based genetic screening throughout Guangxi, China

in Genetics of Common and Rare Diseases

Chunrong Gui
Zifeng Cheng
Yongsheng Chen
Yunting Ma
Hongfei Chen
Wei Wei
Xianda Wei
Juliang Liu
Xu Zhou
Qianqian Du

Frontiers in Genetics

doi 10.3389/fgene.2025.1622391

3,020 views

Case Report

Published on 14 Aug 2025

Case Report: Hereditary neuropathy with liability to pressure palsy (HNPP): the role of genetic investigation in diagnostic assessment

in Neurogenomics

Salvatore Savasta
Fabiola Serra
Lucrezia Galimberti
Francesco Fabrizio Comisi
Marcello Cossu
Alessandro Vannelli
Maddalena Masala
Sara Tanca
Stefania Murru

Frontiers in Genetics

doi 10.3389/fgene.2025.1613022

4,258 views
2 citations

Original Research

Published on 14 Aug 2025

Construction and immunohistochemical validation of a necroptosis-related prognostic signature in bladder cancer and its association with tumor immune infiltration

in Cancer Genetics and Oncogenomics

Tao Wang
Fei Ding
Kai Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1527907

2,942 views

Original Research

Published on 14 Aug 2025

Cis-regulation analysis of RNA m6A methylation and gene expression in colorectal cancer

in Genomic Assay Technology

Zhen-Liang Lin
Pan-Pan Yu
Bei-Lei Ye

Frontiers in Genetics

doi 10.3389/fgene.2025.1622957

3,359 views
1 citation

Original Research

Published on 13 Aug 2025

High-throughput sequencing unravels placental vascular dysfunction and oxidative stress as mechanistic drivers of advanced maternal age-associated pregnancy

in Human and Medical Genomics

Xin Sun
Yao Chen
Feifei Hu
Yumeng Qiao
He Wu
Yao Su
Yue Hu
Jie Wu
Mingli Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1636834

2,603 views

Review

Published on 13 Aug 2025

Machine learning tools for deciphering the regulatory logic of enhancers in health and disease

in Human and Medical Genomics

Spyros Foutadakis
Vasiliki Bourika
Ioanna Styliara
Panagiotis Koufargyris
Asimina Safarika
Eleni Karakike

Frontiers in Genetics

doi 10.3389/fgene.2025.1603687

3,469 views
1 citation

Original Research

Published on 13 Aug 2025

A comprehensive analysis identifies and validates NPC1 as a potential biomarker for prognosis in HCC

in Cancer Genetics and Oncogenomics

Xingjun Lu
Tianyao Gou
Xuxing He
Xia Chen
Daqing Yang
Xiaozhen Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1588583

2,296 views

Case Report

Published on 13 Aug 2025

Case Report: Unmasking the role of rem sleep in modulating non-convulsive status epilepticus in ring chromosome 20 syndrome: a genetic disorder of sleep architecture?

in Genetics of Common and Rare Diseases

Filippo Mandato
Maria Teresa Di Claudio
Umberto Costantino
Francesca Rovito
Orazio Palumbo
Pietro Palumbo
Angela La Neve
Maura Pugliatti
M. Castori
Massimo Carella

Frontiers in Genetics

doi 10.3389/fgene.2025.1626457

2,210 views

Original Research

Published on 13 Aug 2025

Integrative multi-omics analysis and machine learning reveal the unique role of ASCC3 in combination with various immune-related genes in rectal adenocarcinoma

in Cancer Genetics and Oncogenomics

Chuang Miao
Fei Qian

Frontiers in Genetics

doi 10.3389/fgene.2025.1614946

2,953 views

Original Research

Published on 13 Aug 2025

Genetic analysis of non-syndromic peg lateralis using whole-exome sequencing

in Genetics of Common and Rare Diseases

Junglim Choi
Sungnam Kim
Hyunsoo Ahn
Donghyo Kim
Sung-Won Cho
Sanguk Kim
Jae Hoon Lee

Frontiers in Genetics

doi 10.3389/fgene.2025.1572966

2,067 views
1 citation

Original Research

Published on 13 Aug 2025

The association between diabetes and head and neck squamous cell carcinoma: evidence from clinical cohort and bioinformatics analyses

in Cancer Genetics and Oncogenomics

Yurong He
Jiaming Chen
Boxuan Han
Yanming Zhao
Lizhen Hou
Jugao Fang
Meng Lian

Frontiers in Genetics

doi 10.3389/fgene.2025.1660012

2,259 views
2 citations

16,588 articles

articles

High-density SNP-based linkage map construction and QTL analysis for growth-related traits in Luciobarbus brachycephalus using whole-genome resequencing data

Identification of anoikis-related genes to develop a risk model and predict the prognosis and tumor microenvironment in rectal adenocarcinoma

The comparison of the prognostic value of different inflammation-related indicators in patients with oral squamous cell carcinoma

Bioinformatics analysis combined with untargeted metabolomics reveals lipid metabolism-related genes and their biological markers in chronic spontaneous urticaria

Four novel genetic mutations are associated with patent foramen ovale in Tibetan population using whole exome sequencing

A Benchmark of methods for SARS-CoV-2 whole genome sequencing and development of a more sensitive method

New therapeutic targets for endometriosis predicted through mendelian randomization analysis and case-control trials

A retrospective analysis of 38,652 amniotic fluid karyotype

A rare intronic c.2654+1G>A mutation in CSF1R-microglial encephalopathy: a case report

Integrative machine learning and Mendelian randomization identify causal laboratory biomarkers for coronary artery lesions in Kawasaki disease: a prospective study

Genetic basis of phenotypic diversity in C. stenophylla: a stepping stone for climate-adapted coffee cultivar development

Pseudohypoparathyroidism type 1B mimicking gitelman syndrome: diagnostic pitfalls and molecular insights

Shared genetic architecture between grip strength and cognitive function: insights from large-scale genome-wide cross-trait analysis

The rare hemoglobin variants Hb O-Arab and Hb D-Punjab identified in population-based genetic screening throughout Guangxi, China

Case Report: Hereditary neuropathy with liability to pressure palsy (HNPP): the role of genetic investigation in diagnostic assessment

Construction and immunohistochemical validation of a necroptosis-related prognostic signature in bladder cancer and its association with tumor immune infiltration

Cis-regulation analysis of RNA m6A methylation and gene expression in colorectal cancer

High-throughput sequencing unravels placental vascular dysfunction and oxidative stress as mechanistic drivers of advanced maternal age-associated pregnancy

Machine learning tools for deciphering the regulatory logic of enhancers in health and disease

A comprehensive analysis identifies and validates NPC1 as a potential biomarker for prognosis in HCC

Case Report: Unmasking the role of rem sleep in modulating non-convulsive status epilepticus in ring chromosome 20 syndrome: a genetic disorder of sleep architecture?

Integrative multi-omics analysis and machine learning reveal the unique role of ASCC3 in combination with various immune-related genes in rectal adenocarcinoma

Genetic analysis of non-syndromic peg lateralis using whole-exome sequencing

The association between diabetes and head and neck squamous cell carcinoma: evidence from clinical cohort and bioinformatics analyses