Frontiers in Genetics

Original Research

Published on 23 Jun 2025

CYLD as a key regulator of myocardial infarction-to-heart failure transition revealed by multi-omics integration

in Computational Genomics

Jingya Xu
Zhonghua Dong
Zhaodong Li
Xuan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1592985

2,681 views

Original Research

Published on 23 Jun 2025

Insights into the evolution and regulation of miRNAs from the view of their DNA replication temporal domains

in Computational Genomics

Xudong Wu
Tingting Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1544802

1,498 views

Original Research

Published on 23 Jun 2025

Directional genomic hybridization (dGH™) identifies small inverted duplications in situ

in Cytogenomics

Thomas Liehr
Erin Cross
Stefanie Kankel

Frontiers in Genetics

doi 10.3389/fgene.2025.1604822

2,839 views

Original Research

Published on 23 Jun 2025

Uncovering genetic contributors to developmental delay and intellectual disability: a focus on CNVs in pediatric patients

in Cytogenomics

Yilun Tao
Hongzhi Guo
Dong Han
Miao Yang
Ting Lun
Lihong Wang
Wenxia Song
Haiwei Wang
Xiaoze Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1539902

2,465 views

Original Research

Published on 20 Jun 2025

Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma

in Computational Genomics

Di Lian
Chenye Lin
Meiling Xie
JianXing Wei
Xueling Huang
Ke Lian
Qiuyu Tang

Frontiers in Genetics

doi 10.3389/fgene.2025.1557709

2,347 views

Original Research

Published on 20 Jun 2025

Diagnostic yield of 1000 trio analyses with exome and genome sequencing in a clinical setting

in Genetics of Common and Rare Diseases

Helena Malmgren
Malin Kvarnung
Peter Gustafsson
Britt-Marie Anderlid
Cecilia Arthur
Jonas Carlsten
Karl De Geer
Emma Ehn
Giedre Grigelioniené
Anna Hammarsjö

Frontiers in Genetics

doi 10.3389/fgene.2025.1580879

3,215 views

Original Research

Published on 20 Jun 2025

Generalized information criteria for personalized gene network inference

in Computational Genomics

Heewon Park
Seiya Imoto
Sadanori Konishi

Frontiers in Genetics

doi 10.3389/fgene.2025.1583756

1,351 views

Original Research

Published on 20 Jun 2025

Identification of neutrophil extracellular trap-related biomarkers in ulcerative colitis based on bioinformatics and machine learning

in Computational Genomics

Jiao Li
Yupei Liu
Zhiyi Sun
Suqi Zeng
Caisong Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1589999

3,473 views
1 citation

Methods

Published on 19 Jun 2025

GTMALoc: prediction of miRNA subcellular localization based on graph transformer and multi-head attention mechanism

in RNA

Xindi Huang
Jipu Jiang
Lifen Shi
Cheng Yan

Frontiers in Genetics

doi 10.3389/fgene.2025.1623008

1,304 views

Original Research

Published on 19 Jun 2025

Identification of biomarkers associated with mitochondrial dysfunction and programmed cell death in chronic obstructive pulmonary disease via transcriptomics

in Computational Genomics

Xiaojuan Yang
Yutao Duan
Lei Qiu
Xia Huang
Fei Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1567173

2,394 views
1 citation

Original Research

Published on 19 Jun 2025

Two novel variants in CNNM2 disrupts magnesium efflux leading to neurodevelopmental disorders

in Genetics of Common and Rare Diseases

Huijuan Li
Jing Liu
Yingdi Liu
Yaning Liu
Kehui Lu
Juan Wen
Huimin Zhu
Desheng Liang
Zhuo Li
Lingqian Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1600877

2,224 views

Case Report

Published on 18 Jun 2025

Case Report: A case of ALS type 6 associated with a FUS gene variant and right limb muscle weakness and atrophy as the initial symptom

in Genetics of Common and Rare Diseases

Xiuping Zhan
Tingting Xuan
Xiaoyan Chen
Jianhang He
Yazhou Ren
Yue Meng
Guisheng Chen
Haining Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1578249

2,075 views

Brief Research Report

Published on 18 Jun 2025

Novel causative RYR2 indel variant with exon and intron involvement inducing exon 13 skipping in a family exhibiting catecholaminergic polymorphic ventricular tachycardia

in Genetics of Common and Rare Diseases

Ju Hyeon Shin
Taek Kyu Park
Sung-A. Chang
Shin Yi Jang
June Huh
Chang Ahn Seol
Kyoung-Jin Park
Sung Hoon Kim
Duk-Kyung Kim
Hye Bin Gwag

Frontiers in Genetics

doi 10.3389/fgene.2025.1581535

2,061 views

Case Report

Published on 18 Jun 2025

Case Report: A first case of desmin-related myofibrillar myopathy due to inheritance from a confirmed mosaic asymptomatic carrier

in Genetics of Common and Rare Diseases

Jelle Vlaeminck
Sophie Uyttebroeck
Elke De Schutter
Ann Cordenier
Shauni Wellekens
Erwin Ströker
Kelly De Rooms
Christine Helsen
Frederik J. Hes
Philippe Giron

Frontiers in Genetics

doi 10.3389/fgene.2025.1597851

2,010 views

Original Research

Published on 18 Jun 2025

Clinical characteristics and genetic mutation analysis in 18 pediatric patients with Shwachman-Diamond syndrome

in Genetics of Common and Rare Diseases

Ruoying Wei
Kaihui Zhang
Chen Liu
Xuxia Wei
Qin Jiang
Ji-an Li
Meiling Huo
Yinggang Liu
Mohnad Abdalla
Li-an Du

Frontiers in Genetics

doi 10.3389/fgene.2025.1603782

2,088 views

Original Research

Published on 18 Jun 2025

Identification and functional characterization of ABCA4 gene variants in three patients with Stargardt disease or retinitis pigmentosa

in Genetics of Common and Rare Diseases

Qi Luo
Juan Huang
Lu Shi
Guanghong Zhang
Linping Xue
Kehu Wu
Xiaoyu Li
Lei Yang
Dujun Li
Liangwei Mao

Frontiers in Genetics

doi 10.3389/fgene.2025.1516872

3,214 views

Original Research

Published on 18 Jun 2025

A xyloglucan endotransglucosylase/hydrolase gene, IbXTH16, increases cold tolerance in transgenic sweetpotato

in Genomics of Plants and the Phytoecosystem

Tao Yu
Jiaquan Pan
Sitong Liu
Zitong Yang
Zhenlei Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1629260

1,465 views

Original Research

Published on 18 Jun 2025

Epigenetic mechanisms linking atherosclerosis to ischemic stroke: insights from DNA methylation and transcriptome integration

in Neurogenomics

Binrong Ding
Yiqun Wang
Junfeng Li
Xuewei Zhang
Zhengqing Wan
Hao Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1567951

2,113 views

Original Research

Published on 18 Jun 2025

Identification of three T cell-related genes as diagnostic and prognostic biomarkers for triple-negative breast cancer and exploration of potential mechanisms

in Cancer Genetics and Oncogenomics

Zhi-Chuan He
Zheng-Zheng Song
Zhe Wu
Peng-Fei Lin
Xin-Xing Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1584334

2,716 views

Original Research

Published on 18 Jun 2025

Epigenetic study of the long-term effects of gulf War illness

in Epigenomics and Epigenetics

B. C. Jones
J. P. O’Callaghan
D. G. Ashbrook
L. Lu
P. Prins
W. Zhao
K. Mozhui

Frontiers in Genetics

doi 10.3389/fgene.2025.1553410

2,404 views
1 citation

Brief Research Report

Published on 18 Jun 2025

Data simulation to optimize frameworks for genome-wide association studies in diverse populations

in Applied Genetic Epidemiology

Jacquiline W. Mugo
Nicola Mulder
Emile R. Chimusa

Frontiers in Genetics

doi 10.3389/fgene.2025.1559496

2,293 views
1 citation

Original Research

Published on 18 Jun 2025

Role of inflammation-related genes as prognostic biomarkers and mechanistic implications in idiopathic pulmonary fibrosis

in Statistical Genetics and Methodology

Bing Bai
Wenfei Zhao
Fazhan Li
Yang Mi
Pengyuan Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1602588

2,513 views

Original Research

Published on 18 Jun 2025

Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout

in Computational Genomics

Ye Yuan
Zhiqiang Gao
Jianhong Chen
Yuejing Liu
Jingguo Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1598835

2,313 views

Opinion

Published on 18 Jun 2025

Regulation of term and preterm labor: genetics and epigenetics

in Epigenomics and Epigenetics

Kaiyi Sun
Ning Wang
Yuanyuan Liu
Lu Gao

Frontiers in Genetics

doi 10.3389/fgene.2025.1594030

1,743 views

16,444 articles

articles

CYLD as a key regulator of myocardial infarction-to-heart failure transition revealed by multi-omics integration

Insights into the evolution and regulation of miRNAs from the view of their DNA replication temporal domains

Directional genomic hybridization (dGH™) identifies small inverted duplications in situ

Uncovering genetic contributors to developmental delay and intellectual disability: a focus on CNVs in pediatric patients

Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma

Diagnostic yield of 1000 trio analyses with exome and genome sequencing in a clinical setting

Generalized information criteria for personalized gene network inference

Identification of neutrophil extracellular trap-related biomarkers in ulcerative colitis based on bioinformatics and machine learning

GTMALoc: prediction of miRNA subcellular localization based on graph transformer and multi-head attention mechanism

Identification of biomarkers associated with mitochondrial dysfunction and programmed cell death in chronic obstructive pulmonary disease via transcriptomics

Two novel variants in CNNM2 disrupts magnesium efflux leading to neurodevelopmental disorders

Case Report: A case of ALS type 6 associated with a FUS gene variant and right limb muscle weakness and atrophy as the initial symptom

Novel causative RYR2 indel variant with exon and intron involvement inducing exon 13 skipping in a family exhibiting catecholaminergic polymorphic ventricular tachycardia

Case Report: A first case of desmin-related myofibrillar myopathy due to inheritance from a confirmed mosaic asymptomatic carrier

Clinical characteristics and genetic mutation analysis in 18 pediatric patients with Shwachman-Diamond syndrome

Identification and functional characterization of ABCA4 gene variants in three patients with Stargardt disease or retinitis pigmentosa

A xyloglucan endotransglucosylase/hydrolase gene, IbXTH16, increases cold tolerance in transgenic sweetpotato

Epigenetic mechanisms linking atherosclerosis to ischemic stroke: insights from DNA methylation and transcriptome integration

Identification of three T cell-related genes as diagnostic and prognostic biomarkers for triple-negative breast cancer and exploration of potential mechanisms

Epigenetic study of the long-term effects of gulf War illness

Data simulation to optimize frameworks for genome-wide association studies in diverse populations

Role of inflammation-related genes as prognostic biomarkers and mechanistic implications in idiopathic pulmonary fibrosis

Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout

Regulation of term and preterm labor: genetics and epigenetics