Frontiers in Genetics

Original Research

Published on 30 May 2025

Very long-chain acyl-CoA dehydrogenase deficiency revisited: a retrospective genotype–phenotype analysis in a Saudi tertiary center

in Genetics of Common and Rare Diseases

Suzan Suliman Alhumaidi
Fahad Abdulrahman Algaeed
Meshari Fayez Aladhadh
Sara Abdulrahman Alkaff

Frontiers in Genetics

doi 10.3389/fgene.2025.1584817

2,354 views

Original Research

Published on 30 May 2025

Hapten-labeled DNA probes can be stored and used in fluorescence in situ hybridization for decades

in Cytogenomics

Thomas Liehr
Niklas Padutsch
Stefanie Kankel

Frontiers in Genetics

doi 10.3389/fgene.2025.1569308

2,294 views

Original Research

Published on 30 May 2025

Integrative transcriptomics and single-cell transcriptomics analyses reveal potential biomarkers and mechanisms of action in papillary thyroid carcinoma

in Computational Genomics

Wanchen Cao
Kai Gao
Yi Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1536198

2,470 views

Original Research

Published on 30 May 2025

Identification and validation of aging related genes in osteoarthritis

in Genetics of Aging

Jian Du
Tian Zhou
Yanghui Dong
Yunchao Sun
Wei Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1561644

2,968 views

Original Research

Published on 30 May 2025

Reference-free deconvolution of complex samples based on cross-cell-type differential analysis: Systematic evaluations with various feature selection options

in Computational Genomics

Weiwei Zhang
Zhonghe Tian
Ling Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1570781

1,669 views

Original Research

Published on 30 May 2025

Exosomes containing long non-coding RNA AGAP2-AS1 promote the differentiation of CD4+ T cells through the miR-424-5p/SGK1 axis in psoriasis

in RNA

Ziqi Yuan
Xue Zeng
Xiwei Zhang
Chenglai Xia
Xuebiao Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1521470

2,095 views

Original Research

Published on 30 May 2025

Effects of salinity stress on morphological structure, physiology, and mRNA expression in different wheat (Triticum aestivum L.) cultivars

in Genomics of Plants and the Phytoecosystem

Xiaohui Sun
Yuliu Tan
Yumei Zhang
Weiwei Guo
Ximei Li
Nataliia Golub
Lili Zhang
Huifang Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1535610

3,748 views
1 citation

Original Research

Published on 30 May 2025

Identification of biomarkers for the diagnosis of chronic kidney disease (CKD) with dilated cardiomyopathy (DCM) by bioinformatics analysis and machine learning

in Computational Genomics

Yuhang Liu
Yong Wang
Wenyang Nie
Zhen Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1562891

3,504 views
1 citation

Original Research

Published on 30 May 2025

Identification and functional characteristics of a novel splice site variant in L1CAM caused X-linked hydrocephalus

in Genetics of Common and Rare Diseases

Shijie Zhou
Hao Zhang
Xue Li
Quan Chen
Zhihong Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1588709

1,732 views

Original Research

Published on 30 May 2025

A non-invasive method for screening mitochondrial diabetes

in Genetics of Common and Rare Diseases

Hangyu Fang
Xiaoe Li
Shuping Wang
Mei Zhang
Victor Wei Zhang
Chao Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1536331

2,360 views

Review

Published on 30 May 2025

Research progress of colorectal cancer in genomic and transcriptomic at multi-level

in Cancer Genetics and Oncogenomics

Qinglian Wen
Shuangyan Han
Yongxia Cui

Frontiers in Genetics

doi 10.3389/fgene.2025.1533817

3,800 views
1 citation

Editorial

Published on 29 May 2025

Editorial: Computational genomic and precision medicine

in Computational Genomics

Zeeshan Ahmed
Ramkumar Thirunavukarasu
Atlas Khan

Frontiers in Genetics

doi 10.3389/fgene.2025.1631668

2,138 views

Original Research

Published on 29 May 2025

Clinical impact of pharmacogenomics in pediatric care: insights extracted from clinical exome sequencing

in Pharmacogenetics and Pharmacogenomics

Simran Maggo
Yachen Pan
Dejerianne Ostrow
Jenny Q. Nguyen
Jaclyn A. Biegel
Matthew A. Deardorff
Xiaowu Gai

Frontiers in Genetics

doi 10.3389/fgene.2025.1574325

3,453 views

Original Research

Published on 29 May 2025

Elucidating the role of pyrabactin-like receptors of finger millet under drought and salinity stress: an insight into in silico, machine learning and molecular approaches

in Genomics of Plants and the Phytoecosystem

Varsha Rani
Theivanayagam Maharajan
Shefali Singh
D. C. Joshi
Ramwant Gupta
Dinesh Yadav

Frontiers in Genetics

doi 10.3389/fgene.2025.1598523

2,142 views

Editorial

Published on 29 May 2025

Editorial: Statistical approaches, applications, and software for longitudinal microbiome data analysis and microbiome multi-omics data integration

in Statistical Genetics and Methodology

Huilin Li
Jun Chen
Mogens Fenger
Yuan Jiang

Frontiers in Genetics

doi 10.3389/fgene.2025.1624791

1,610 views

Editorial

Published on 29 May 2025

Editorial: High-throughput sequencing-based investigation of chronic disease markers and mechanisms, volume II

in Human and Medical Genomics

Hua Li
Guoshuai Cai
Wen-Lian Chen
Xiaodong Zhao
Yuriy L. Orlov

Frontiers in Genetics

doi 10.3389/fgene.2025.1627976

1,464 views

Original Research

Published on 27 May 2025

MultiV_Nm: a prediction method for 2′-O-methylation sites based on multi-view features

in RNA

Lei Bai
Fei Liu
Yile Wang
Junle Su
Lian Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1608490

1,540 views
3 citations

Original Research

Published on 26 May 2025

Uncovering codon usage patterns during murine embryogenesis and tissue-specific developmental diseases

in Statistical Genetics and Methodology

Sarah E. Fumagalli
Sean Smith
Brian Lin
Rahul Paul
Collin Campbell
Luis Santana-Quintero
Anton Golikov
Juan Ibla
Haim Bar
Anton A. Komar

Frontiers in Genetics

doi 10.3389/fgene.2025.1554773

1,864 views

Original Research

Published on 26 May 2025

Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population

in Applied Genetic Epidemiology

Alexander Owusu Boakye
Christian Obirikorang
Anthony Afum-Adjei Awuah
Evans Asamoah Adu
Doris Winter
Eric Ebenezer Boham
Hakim Alani
Sylvester Kofi Newton
Nana Safi Toure Almoustapha
James Deke

Frontiers in Genetics

doi 10.3389/fgene.2025.1555515

2,692 views

Original Research

Published on 26 May 2025

Prediction of mild cognitive impairment using blood multi-omics data

in Computational Genomics

Daniel Frank Zhang
Cigdem Sevim Bayrak
Qi Zeng
Minghui Wang
Bin Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1552063

2,435 views

Case Report

Published on 26 May 2025

Case Report: A neurodevelopmental disorder with global developmental delay, microcephaly, eye anomalies, sweat dysregulation, and skeletal implications due to an ultra-rare de novo 5q14.3q15 copy number gain

in Human and Medical Genomics

Costela Lacrimioara Serban
Alexandra Mihailescu
Diana Miclea
Cristian G. Zimbru
Florina Stoica
Adela Chirita-Emandi

Frontiers in Genetics

doi 10.3389/fgene.2025.1549685

1,854 views

Case Report

Published on 26 May 2025

Case Report: Multiple cerebral infarctions in a patient with hereditary hemorrhagic telangiectasia following a fall

in Genetics of Common and Rare Diseases

Linting Gu
Sheng Chen
Wenwei Li
Fanlong Ye

Frontiers in Genetics

doi 10.3389/fgene.2025.1581625

2,017 views

Brief Research Report

Published on 23 May 2025

Molecular variants of multiple genes were revealed by whole-exome sequencing in PCOS patients with diabetes

in Genetics of Common and Rare Diseases

Chenglin Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1541946

2,763 views

Original Research

Published on 23 May 2025

The role of E2F1 in promoting EIF4EBP1 transcription in cryptorchid mice: association with autophagy in germ cells

in Applied Genetic Epidemiology

Jianguo Zhang
Yanhui Liu
Hailong Zhang
Lin Yang
Danjing Sun
Lili Xiao
Xiaoyun Wang
Xiangming Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1536672

1,691 views

16,441 articles

articles

Very long-chain acyl-CoA dehydrogenase deficiency revisited: a retrospective genotype–phenotype analysis in a Saudi tertiary center

Hapten-labeled DNA probes can be stored and used in fluorescence in situ hybridization for decades

Integrative transcriptomics and single-cell transcriptomics analyses reveal potential biomarkers and mechanisms of action in papillary thyroid carcinoma

Identification and validation of aging related genes in osteoarthritis

Reference-free deconvolution of complex samples based on cross-cell-type differential analysis: Systematic evaluations with various feature selection options

Exosomes containing long non-coding RNA AGAP2-AS1 promote the differentiation of CD4+ T cells through the miR-424-5p/SGK1 axis in psoriasis

Effects of salinity stress on morphological structure, physiology, and mRNA expression in different wheat (Triticum aestivum L.) cultivars

Identification of biomarkers for the diagnosis of chronic kidney disease (CKD) with dilated cardiomyopathy (DCM) by bioinformatics analysis and machine learning

Identification and functional characteristics of a novel splice site variant in L1CAM caused X-linked hydrocephalus

A non-invasive method for screening mitochondrial diabetes

Research progress of colorectal cancer in genomic and transcriptomic at multi-level

Editorial: Computational genomic and precision medicine

Clinical impact of pharmacogenomics in pediatric care: insights extracted from clinical exome sequencing

Elucidating the role of pyrabactin-like receptors of finger millet under drought and salinity stress: an insight into in silico, machine learning and molecular approaches

Editorial: Statistical approaches, applications, and software for longitudinal microbiome data analysis and microbiome multi-omics data integration

Editorial: High-throughput sequencing-based investigation of chronic disease markers and mechanisms, volume II

MultiV_Nm: a prediction method for 2′-O-methylation sites based on multi-view features

Uncovering codon usage patterns during murine embryogenesis and tissue-specific developmental diseases

Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population

Prediction of mild cognitive impairment using blood multi-omics data

Case Report: A neurodevelopmental disorder with global developmental delay, microcephaly, eye anomalies, sweat dysregulation, and skeletal implications due to an ultra-rare de novo 5q14.3q15 copy number gain

Case Report: Multiple cerebral infarctions in a patient with hereditary hemorrhagic telangiectasia following a fall

Molecular variants of multiple genes were revealed by whole-exome sequencing in PCOS patients with diabetes

The role of E2F1 in promoting EIF4EBP1 transcription in cryptorchid mice: association with autophagy in germ cells