Frontiers in Genetics

Original Research

Published on 21 Feb 2025

Exploration of cfDNA landscape in NIPT and clinical utilities of cfDNA based gene expression inference in prenatal diagnostics

in Human and Medical Genomics

Ruo Jia
Jianjiang Zhu
Feng Zhang
Yangbo Sun
Bin Zhang
Yang Du
Hong Qi

Frontiers in Genetics

doi 10.3389/fgene.2025.1527884

3,317 views
2 citations

Original Research

Published on 21 Feb 2025

Comprehensive analysis of non-coding RNA-mediated endothelial cell-specific regulatory circuits in coronary artery disease risk

in Computational Genomics

Boshui Huang
Zhijie Lai
Xiaoyu Wang
Qinhao Zhang
Tingting Hu
Fulong Yu
Shuxian Zhou
Yan Zhang
Juan Meng

Frontiers in Genetics

doi 10.3389/fgene.2025.1559798

1,894 views
1 citation

Brief Research Report

Published on 20 Feb 2025

Calculating maternal polygenic risk scores from prenatal screening by cell-free DNA data

in Human and Medical Genomics

Victoria Corey
Mauro Chavez
Layla Qasim
Tevfik U. Dincer
Angela Henry
Salome Bagayan
Sasha Treadup
Mike Mehan
Eileen de Feo
Sung Kim

Frontiers in Genetics

doi 10.3389/fgene.2025.1495604

2,501 views

Original Research

Published on 20 Feb 2025

High-throughput microRNA sequencing in the developing branchial arches suggests miR-92b-3p regulation of a cardiovascular gene network

in RNA

Sian Goldsworthy
Marta Losa
Nicoletta Bobola
Sam Griffiths-Jones

Frontiers in Genetics

doi 10.3389/fgene.2025.1514925

1,567 views
1 citation

Original Research

Published on 20 Feb 2025

Deciphering the role of CNIH4 in pan-cancer landscapes and its significance in breast cancer progression

in Cancer Genetics and Oncogenomics

Yao Xu
Zengzhen Lai
Chaolin Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1536620

2,358 views

Systematic Review

Published on 20 Feb 2025

Comprehensive systematic review and meta-analysis of the TGF-β1 T869C gene polymorphism and autoimmune disease susceptibility

in Genetics of Common and Rare Diseases

Yawen Zhu
Ai Qian
Yuanyuan Cheng
Ming Li
Chuanbing Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1502921

2,773 views
2 citations

Original Research

Published on 20 Feb 2025

EDN1 and NTF3 in keloid pathogenesis: computational and experimental evidence as novel diagnostic biomarkers for fibrosis and inflammation

in Computational Genomics

Hui Gong
Jing Liu
Nanji Chen
Hengguang Zhao
Bailin He
Hongpei Zhang
Wenping Wang
Yi Tian

Frontiers in Genetics

doi 10.3389/fgene.2025.1516451

2,848 views
1 citation

Correction

Published on 20 Feb 2025

Corrigendum: Integrated network analysis to identify key modules and potential hub genes involved in bovine respiratory disease: a systems biology approach

in Livestock Genomics

Aliakbar Hasankhani
Abolfazl Bahrami
Negin Sheybani
Farhang Fatehi
Roxana Abadeh
Hamid Ghaem Maghami Farahani
Mohammad Reza Bahreini Behzadi
Ghazaleh Javanmard
Sadegh Isapour
Hosein Khadem

Frontiers in Genetics

doi 10.3389/fgene.2025.1572285

1,031 views

Systematic Review

Published on 20 Feb 2025

Correlation and clinical significance of GSTP1 hypermethylation in hepatocellular carcinoma: a systematic review and meta-analysis

in Pharmacogenetics and Pharmacogenomics

Pengfei Li
Lei He
Chunxia Zhang
Xinyao Huang
Rong Sun
Yan Zhang
Yan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1543261

2,611 views
1 citation

Editorial

Published on 19 Feb 2025

Editorial: Advancements and prospects of genome-wide association studies

in Applied Genetic Epidemiology

Ayo P. Doumatey
Yafang Li
Juan Carlos Fernandez-Lopez

Frontiers in Genetics

doi 10.3389/fgene.2025.1564006

2,885 views

Editorial

Published on 18 Feb 2025

Editorial: Challenges and prospects for conservation genetics at XXI century

in Evolutionary and Population Genetics

Patricia Amavet
Gabriela P. Fernández
Viviana Solís Neffa

Frontiers in Genetics

doi 10.3389/fgene.2025.1554590

1,435 views

Original Research

Published on 18 Feb 2025

Identification of cancer-associated fibroblast signature genes for prognostic prediction in colorectal cancer

in Cancer Genetics and Oncogenomics

Wei Jin
Yuchang Lu
Jingen Lu
Zhenyi Wang
Yixin Yan
Biao Liang
Shiwei Qian
Jiachun Ni
Yiheng Yang
Shuo Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1476092

5,749 views
3 citations

Editorial

Published on 18 Feb 2025

Editorial: Recent advances in causes, diagnosis, and therapeutics for congenital heart defects

in Genetics of Common and Rare Diseases

Xinxiu Xu
Cecilia W. Lo
Lisa J. Martin
Lu Han
Dongzhu Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1564492

1,993 views

Correction

Published on 18 Feb 2025

Corrigendum: Construction of a circRNA–lincRNA–lncRNA–miRNA–mRNA ceRNA regulatory network identifies genes and pathways linked to goat fertility

in Livestock Genomics

Farzad Ghafouri
Mostafa Sadeghi
Abolfazl Bahrami
Masoumeh Naserkheil
Vahid Dehghanian Reyhan
Arash Javanmard
Seyed Reza Miraei-Ashtiani
Soheila Ghahremani
Herman W. Barkema
Rostam Abdollahi-Arpanahi

Frontiers in Genetics

doi 10.3389/fgene.2025.1422201

1,521 views

Correction

Published on 17 Feb 2025

Corrigendum: Zearalenone exposure enhanced the expression of tumorigenesis genes in donkey granulosa cells via the PTEN/PI3K/AKT signaling pathway

in Predictive Toxicology and Exposomics

Guo-Liang Zhang
Jun-Lin Song
Chuan-Liang Ji
Yu-Long Feng
Jie Yu
Charles M. Nyachoti
Gong-She Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1564143

1,225 views

Case Report

Published on 17 Feb 2025

Case report: A novel intronic JMJD6 likely pathogenic variant (c.941+75G > T) associated with congenital eyelid coloboma in one of the identical twin sisters

in Genetics of Common and Rare Diseases

Xin Li
Yuqi Zhang
Gang Chai
Weijie Su
Yan Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1536000

1,637 views

Original Research

Published on 17 Feb 2025

Exploration and verification of circulating diagnostic biomarkers in osteoarthritis based on machine learning

in Human and Medical Genomics

Xinyu Wang
Tianyi Liu
Yueyang Sheng
Cheng Qiu
Yanzhuo Zhang
Yanqun Liu
Chengai Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1513675

2,953 views

Original Research

Published on 17 Feb 2025

Exploring genetic loci linked to COVID-19 severity and immune response through multi-trait GWAS analyses

in Applied Genetic Epidemiology

Ziang Meng
Chumeng Zhang
Shuai Liu
Wen Li
Yue Wang
Qingyi Zhang
Bichen Peng
Weiyi Ye
Yue Jiang
Yingchao Song

Frontiers in Genetics

doi 10.3389/fgene.2025.1502839

2,733 views
1 citation

Original Research

Published on 17 Feb 2025

Role of PD-L1 in mediating the effect of lipid on ulcerative colitis: a mediation Mendelian randomization study

in Statistical Genetics and Methodology

Peihong Li
Yiwen Wang
Hongyi Hu
Boyun Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1390605

2,275 views
1 citation

Original Research

Published on 17 Feb 2025

Alteration of chromatin states perturb the transcription regulation of gene during hydronephrosis

in RNA

Xiao-Hui Wang
Shu-Feng Zhang
Hai-Ying Wu
Jian Gao
Lin Wang
Yao Yin
Xuhui Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1396073

1,991 views

Methods

Published on 17 Feb 2025

WCSGNet: a graph neural network approach using weighted cell-specific networks for cell-type annotation in scRNA-seq

in Computational Genomics

Yi-Ran Wang
Pu-Feng Du

Frontiers in Genetics

doi 10.3389/fgene.2025.1553352

2,973 views
2 citations

Original Research

Published on 13 Feb 2025

Distinct gene signatures define the epithelial cell features of mucinous appendiceal neoplasms and pseudomyxoma metastases

in Cancer Genetics and Oncogenomics

Carlos Ayala
Anuja Sathe
Xiangqi Bai
Susan M. Grimes
Jeanne Shen
George A. Poultsides
Byrne Lee
Hanlee P. Ji

Frontiers in Genetics

doi 10.3389/fgene.2025.1536982

3,172 views
3 citations

Editorial

Published on 13 Feb 2025

Editorial: Advances and trends in gene expression, regulation, and phenotypic variation in livestock science: a comprehensive review of methods and technologies

in Livestock Genomics

Priyanka Banerjee
Andressa Oliveira de Lima
Loan T. Nguyen
Wellison J. S. Diniz

Frontiers in Genetics

doi 10.3389/fgene.2025.1565301

1,665 views

Original Research

Published on 13 Feb 2025

A comparison of design algorithms for choosing the training population in genomic models

in Statistical Genetics and Methodology

Alexandra Stadler
Werner G. Müller
Andreas Futschik

Frontiers in Genetics

doi 10.3389/fgene.2024.1462855

1,821 views
1 citation

16,444 articles

articles

Exploration of cfDNA landscape in NIPT and clinical utilities of cfDNA based gene expression inference in prenatal diagnostics

Comprehensive analysis of non-coding RNA-mediated endothelial cell-specific regulatory circuits in coronary artery disease risk

Calculating maternal polygenic risk scores from prenatal screening by cell-free DNA data

High-throughput microRNA sequencing in the developing branchial arches suggests miR-92b-3p regulation of a cardiovascular gene network

Deciphering the role of CNIH4 in pan-cancer landscapes and its significance in breast cancer progression

Comprehensive systematic review and meta-analysis of the TGF-β1 T869C gene polymorphism and autoimmune disease susceptibility

EDN1 and NTF3 in keloid pathogenesis: computational and experimental evidence as novel diagnostic biomarkers for fibrosis and inflammation

Corrigendum: Integrated network analysis to identify key modules and potential hub genes involved in bovine respiratory disease: a systems biology approach

Correlation and clinical significance of GSTP1 hypermethylation in hepatocellular carcinoma: a systematic review and meta-analysis

Editorial: Advancements and prospects of genome-wide association studies

Editorial: Challenges and prospects for conservation genetics at XXI century

Identification of cancer-associated fibroblast signature genes for prognostic prediction in colorectal cancer

Editorial: Recent advances in causes, diagnosis, and therapeutics for congenital heart defects

Corrigendum: Construction of a circRNA–lincRNA–lncRNA–miRNA–mRNA ceRNA regulatory network identifies genes and pathways linked to goat fertility

Corrigendum: Zearalenone exposure enhanced the expression of tumorigenesis genes in donkey granulosa cells via the PTEN/PI3K/AKT signaling pathway

Case report: A novel intronic JMJD6 likely pathogenic variant (c.941+75G > T) associated with congenital eyelid coloboma in one of the identical twin sisters

Exploration and verification of circulating diagnostic biomarkers in osteoarthritis based on machine learning

Exploring genetic loci linked to COVID-19 severity and immune response through multi-trait GWAS analyses

Role of PD-L1 in mediating the effect of lipid on ulcerative colitis: a mediation Mendelian randomization study

Alteration of chromatin states perturb the transcription regulation of gene during hydronephrosis

WCSGNet: a graph neural network approach using weighted cell-specific networks for cell-type annotation in scRNA-seq

Distinct gene signatures define the epithelial cell features of mucinous appendiceal neoplasms and pseudomyxoma metastases

Editorial: Advances and trends in gene expression, regulation, and phenotypic variation in livestock science: a comprehensive review of methods and technologies

A comparison of design algorithms for choosing the training population in genomic models