Frontiers in Genetics

Original Research

Published on 08 Jan 2026

Systematic analysis of anoikis-related genes identifies SRPX2-FAK/AKT-IL-6 axis in the progression and peritoneal metastasis of gastric cancer

in Cancer Genetics and Oncogenomics

Dong Hou
Jinhao Yu
Yequan Xie
Shengning Zhou
Jintao Zeng
Mingtao Liang
Fang Zheng
Jianan Tan
Fanghai Han

Frontiers in Genetics

doi 10.3389/fgene.2025.1736097

1,499 views

Case Report

Published on 08 Jan 2026

Case Report: Novel GLA mutation in a Chinese female with renal-predominant Fabry disease and cardiac hypertrophy

in Genetics of Common and Rare Diseases

Lanxin Li
Tianyu Chang
Xichen Li
Yinglu Hao
Min Deng
Yanping Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1664286

940 views

Review

Published on 07 Jan 2026

Exploring the role and therapeutic potential of RNA N6-methyladenosine modification in abortion disease pathology: a comprehensive review

in Epigenomics and Epigenetics

Zhuo Chang
Lu-Hao Li
Liang-Zhen Lv
Zhao-Di Wang
Qing-yi Wang
Hui Zhu
Bei Jiang
Xue-Ming Zhou
Ya-Peng Han
Xue Pan

Frontiers in Genetics

doi 10.3389/fgene.2025.1720842

1,030 views

Methods

Published on 07 Jan 2026

Resilience and evolutionary insights in PPI networks: comparative analysis of node resilience and centrality measures

in Computational Genomics

Jiarui Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1613475

779 views

Original Research

Published on 07 Jan 2026

DDA-bench: a manually curated database for benchmarking datasets and baseline performance values in predicting drug-disease associations

in Computational Genomics

Han Xing
Yongjian Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1755600

785 views

Case Report

Published on 07 Jan 2026

Case Report: Myoclonic and tremulous movements associated with COQ8A-related coenzyme Q10 deficiency type 4

in Genetics of Common and Rare Diseases

Di Wang
Guojian Zhang
Xiaojing Fang
Fang Liu
Li Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1682085

974 views

Original Research

Published on 07 Jan 2026

(Not) “just your nature”. Diagnostic journeys of adults with neurofibromatosis type 1 in Poland

in ELSI in Science and Genetics

Katarzyna Kowal
Jan Domaradzki

Frontiers in Genetics

doi 10.3389/fgene.2025.1713304

1,126 views

Original Research

Published on 07 Jan 2026

Biobanking as a research accelerator: the perspectives of medical students and interns at a saudi university

in ELSI in Science and Genetics

Leena AbuOmar
Mariam M. Al Eissa
Hani Tamim
Sadeq Abu-Dawas
Ahmed Yaqinuddin
Khaled Alkattan

Frontiers in Genetics

doi 10.3389/fgene.2025.1687927

1,054 views

Original Research

Published on 07 Jan 2026

Salmonella enterica serovar Typhimurium-induced alterations in inflammatory chemokine mRNA expressions and hemato-biochemical variations in three different strains of chicken

in Livestock Genomics

Shabir Mir
Nazir A. Ganai
Syed M. Ahmad
Ishraq Hussain
Gowhar G. Sheikh
Nusrat Nabi
Hassan A. Rudayni
Ahmed A. Allam

Frontiers in Genetics

doi 10.3389/fgene.2025.1645142

1,017 views

Original Research

Published on 07 Jan 2026

TPM1-p.E181K mutation suppresses CaMKII/HDAC4 signaling pathway leading to pediatric restrictive cardiomyopathy

in Genetics of Common and Rare Diseases

Jia Fu
Jing Zhang
Youxian Zhang
Dongming Sun
Kun Xia
Ruigeng Wang
Xiaoyuan Feng
Aiguo Zhai
Yufeng Huang
Xiaobin Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1654907

975 views

Review

Published on 07 Jan 2026

Impact of exercise-induced DNA damage repair on age-related muscle weakness and sarcopenia

in Genetics of Aging

Lingyan Zhu
Yiping Su
Zhanguo Su

Frontiers in Genetics

doi 10.3389/fgene.2025.1639224

2,240 views

Original Research

Published on 06 Jan 2026

Genomic and ancestral variations linked to the development of post-acute sequelae of SARS-CoV-2 infection in Indian populations

in Genetics of Common and Rare Diseases

Pooja Umesh Shenoy
Hrushikesh Udupa
A. I. Ananthakrishnan
Punya Sunil
Urvinder Kaur Sardarni
Narendra Kumar
Arpan Acharya
Siddappa N. Byrareddy
Priyanka Upadhyai
Ranajit Das

Frontiers in Genetics

doi 10.3389/fgene.2025.1696764

1,793 views

Original Research

Published on 06 Jan 2026

Integrated network toxicology, machine learning algorithms and TMT proteomics reveal the mechanism of 18β glycyrrhetinic acid against gastric cancer

in Cancer Genetics and Oncogenomics

Doudou Lu
Shumin Jia
Yahong Li
Zhaozhao Wang
Ziying Zhou
Wenjing Liu
Lei Zhang
Ling Yuan
Yi Nan

Frontiers in Genetics

doi 10.3389/fgene.2025.1688077

1,135 views

Original Research

Accepted on 05 Jan 2026

Whole-genome sequencing reveals genomic diversity and selection signatures for adaptation in South African Afrikaner and Bonsmara cattle

in Livestock Genomics

Danielle Alberts
Este van Marle-Köster
Fourie Joubert
Donagh Berry

Frontiers in Genetics

322 views

Case Report

Published on 05 Jan 2026

Case Report: genotype–phenotype correlations in FLNA mutations: insights from a case of multisystem dysfunction

in Genetics of Common and Rare Diseases

Jie Liu
Xin Pan
Lina Qiao
Yi Liao
Zhongqiang Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1693117

1,083 views

Case Report

Published on 05 Jan 2026

Retinitis pigmentosa and sensorineural deafness associated with a de novo DHX16 mutation: case report

in Genetics of Common and Rare Diseases

Lei Wang
Jiyong Gao
Meng Sun
Li Fan
Shuhua Wang
Xue Li
Shuangyu Gu
Bingjuan Han

Frontiers in Genetics

doi 10.3389/fgene.2025.1685906

1,334 views

Perspective

Published on 05 Jan 2026

Monitoring diversity in genome-wide association studies requires measuring and reporting on immigration-related factors

in Applied Genetic Epidemiology

Yao Tu
Lindsay Fernandez-Rhodes

Frontiers in Genetics

doi 10.3389/fgene.2025.1725866

1,006 views

Case Report

Published on 05 Jan 2026

Familial multiple fetal cerebral arteriovenous malformations: a case report of maternal genetic susceptibility and fetal manifestation

in Genetics of Common and Rare Diseases

Hao Wang
Yan Jiang
YanLin Chen
GongLi Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1570754

798 views

Original Research

Published on 05 Jan 2026

Protein kinase Pi65 regulates rice blast resistance through phosphorylation-dependent signaling and metabolic reprogramming

in Genomics of Plants and the Phytoecosystem

Lili Wang
Hongwei Chen
Xiaohang Zhou
Bowen Yan
Zhiqiang Tang
Zuobin Ma
Dianrong Ma
Wenjing Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1715247

998 views

Original Research

Published on 05 Jan 2026

Conditional trust as a driver of public engagement in Korea’s national project of bio-big data

in ELSI in Science and Genetics

Jae Sun Kim
Seohyun Kim
Cheyeon Lee
Wonoh Jeong
Huiwon No
Sungsoo Lim
Yul Jung
Ilhak Lee
Kwangmo Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1713598

1,282 views

Original Research

Published on 05 Jan 2026

Expanding the mutational spectrum of congenital microcephaly in Pakistani families

in Genetics of Common and Rare Diseases

Sundas Farooq
Maria Asif
Ansar A. Abbasi
Zahid Latif
Bonsu Ku
Ehtisham Ul Haq Makhdoom
Madiha Shadab
Muzammil Ahmad Khan
Muhammad Muzammal
Raja Waqar

Frontiers in Genetics

doi 10.3389/fgene.2025.1709083

1,435 views

Original Research

Published on 05 Jan 2026

scVAR: integrating genomics and transcriptomics from single-cell RNA-seq —insights from leukemia case studies

in Computational Genomics

Ludovica Celli
Samuele Manessi
Matteo Barcella
Ivan Merelli

Frontiers in Genetics

doi 10.3389/fgene.2025.1604484

1,244 views

Mini Review

Published on 05 Jan 2026

Metabolic reprogramming in clear cell renal cell carcinoma: core pathways and targeted therapeutic strategies

in Cancer Genetics and Oncogenomics

MingWei Zhan
BinBin Zhao
Haote Chen
Junjie Wu
Run Shi
Feng Gao
Lin Zhao
Jingyu Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1752384

1,589 views

Original Research

Published on 05 Jan 2026

Nanopore sequencing enables combined detection of USP7 variants and a known Hao-Fountain syndrome episignature

in Epigenomics and Epigenetics

Liselot van der Laan
Martin A. Haagmans
Andrea Venema
Jennifer Kerkhof
Michael A. Levy
Silvana Briuglia
Pilar Caro
Sebastian Sailer
Christian P. Schaaf
Bekim Sadikovic

Frontiers in Genetics

doi 10.3389/fgene.2025.1730165

1,696 views

16,574 articles

articles

Systematic analysis of anoikis-related genes identifies SRPX2-FAK/AKT-IL-6 axis in the progression and peritoneal metastasis of gastric cancer

Case Report: Novel GLA mutation in a Chinese female with renal-predominant Fabry disease and cardiac hypertrophy

Exploring the role and therapeutic potential of RNA N6-methyladenosine modification in abortion disease pathology: a comprehensive review

Resilience and evolutionary insights in PPI networks: comparative analysis of node resilience and centrality measures

DDA-bench: a manually curated database for benchmarking datasets and baseline performance values in predicting drug-disease associations

Case Report: Myoclonic and tremulous movements associated with COQ8A-related coenzyme Q10 deficiency type 4

(Not) “just your nature”. Diagnostic journeys of adults with neurofibromatosis type 1 in Poland

Biobanking as a research accelerator: the perspectives of medical students and interns at a saudi university

Salmonella enterica serovar Typhimurium-induced alterations in inflammatory chemokine mRNA expressions and hemato-biochemical variations in three different strains of chicken

TPM1-p.E181K mutation suppresses CaMKII/HDAC4 signaling pathway leading to pediatric restrictive cardiomyopathy

Impact of exercise-induced DNA damage repair on age-related muscle weakness and sarcopenia

Genomic and ancestral variations linked to the development of post-acute sequelae of SARS-CoV-2 infection in Indian populations

Integrated network toxicology, machine learning algorithms and TMT proteomics reveal the mechanism of 18β glycyrrhetinic acid against gastric cancer

Whole-genome sequencing reveals genomic diversity and selection signatures for adaptation in South African Afrikaner and Bonsmara cattle

Case Report: genotype–phenotype correlations in FLNA mutations: insights from a case of multisystem dysfunction

Retinitis pigmentosa and sensorineural deafness associated with a de novo DHX16 mutation: case report

Monitoring diversity in genome-wide association studies requires measuring and reporting on immigration-related factors

Familial multiple fetal cerebral arteriovenous malformations: a case report of maternal genetic susceptibility and fetal manifestation

Protein kinase Pi65 regulates rice blast resistance through phosphorylation-dependent signaling and metabolic reprogramming

Conditional trust as a driver of public engagement in Korea’s national project of bio-big data

Expanding the mutational spectrum of congenital microcephaly in Pakistani families

scVAR: integrating genomics and transcriptomics from single-cell RNA-seq —insights from leukemia case studies

Metabolic reprogramming in clear cell renal cell carcinoma: core pathways and targeted therapeutic strategies

Nanopore sequencing enables combined detection of USP7 variants and a known Hao-Fountain syndrome episignature