Frontiers in Genetics

Original Research

Published on 23 Oct 2025

Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia

in Computational Genomics

Yu Zhou
Shuang Zhang
Yao-Xia Liu
Xin Dai
Ting Zhang
Xiao-Tao Xu
Sheng-Nan Deng
Min-Yan Yang
Zhen Fan

Frontiers in Genetics

doi 10.3389/fgene.2025.1690947

1,723 views

Case Report

Published on 23 Oct 2025

Case Report: a novel missense variant of FGD5 in a family with tetralogy of Fallot

in Genetics of Common and Rare Diseases

Meng-Wei Liu
Yi Dong
Rong Xiang
Liping Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1663959

1,767 views

Original Research

Published on 23 Oct 2025

A newly discovered Lnc-PDZD7-3 increased metastatic and proliferative potential of lung adenocarcinoma cells via modulating FN1/fibronectin signaling

in Cancer Genetics and Oncogenomics

Guodong Zhang
Jianbo Zhang
Fachang Yu
Xiaohe Hao

Frontiers in Genetics

doi 10.3389/fgene.2025.1618449

1,262 views
1 citation

Original Research

Published on 23 Oct 2025

aiGeneR 3.0: an enhanced deep network model for resistant strain identification and multi-drug resistance prediction in Escherichia coli causing urinary tract infection using next-generation sequencing data

in Pharmacogenetics and Pharmacogenomics

Debasish Swapnesh Kumar Nayak
Abhilash Pati
Amrutanshu Panigrahi
Mudassir Khan
Bayan Alabdullah
Santanu Kumar Sahoo
Bibhuprasad Sahu
Abrar Almjally
Saurav Mallik
Tripti Swarnkar

Frontiers in Genetics

doi 10.3389/fgene.2025.1651917

1,743 views

Correction

Published on 23 Oct 2025

Correction: Heat shock protein 27 phosphorylation state is associated with cancer progression

in Systems Biology Archive

Maria Katsogiannou
Claudia Andrieu
Palma Rocchi

Frontiers in Genetics

doi 10.3389/fgene.2025.1703072

882 views

Original Research

Published on 22 Oct 2025

A novel frameshift variant of PAX3 in a Chinese Yugur family with Waardenburg syndrome type 1

in Genetics of Common and Rare Diseases

Lupeng Zhan
Baicheng Xu
Dujuan Lin
Ya Wang
Panpan Bian

Frontiers in Genetics

doi 10.3389/fgene.2025.1679351

1,382 views

Original Research

Published on 22 Oct 2025

S100A10 knockdown exacerbates phenylephrine-induced cardiomyocyte hypertrophy via modulating mitochondrial oxidative phosphorylation

in Cytogenomics

Feixue Xu
Yajie Chen
Man Xu
Dan Li
Yinshan Lu
Meng Zhang
Jiahao Li
Wanyi Li
Yingying Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1610008

1,507 views

Editorial

Published on 22 Oct 2025

Editorial: Decoding complexity: genomic, epigenomic, and environmental dynamics in developmental and neurogenetic disorders

in Epigenomics and Epigenetics

Alessandro Fiorenzano
Luísa Azevedo

Frontiers in Genetics

doi 10.3389/fgene.2025.1724013

1,250 views

Case Report

Published on 21 Oct 2025

Case Report: Clinical and molecular features of a radiosensitive autoimmune polyendocrine syndrome type 1 patient with oral carcinoma

in Genetics of Common and Rare Diseases

Asma Chikhaoui
Houda Hammami-Ghorbel
Dorra Najjar
Semia Zarraa
Safia Yahiaoui
Davor Lessel
Houda Yacoub-Youssef

Frontiers in Genetics

doi 10.3389/fgene.2025.1588108

1,758 views

Original Research

Published on 21 Oct 2025

A novel mechanism by which c-MYC is aberrantly activated by epigenetic silencing of its antisense lncRNA in colon cancer

in Cancer Genetics and Oncogenomics

Xuming Hu
Ye Wei
Meiying Zhang
Chunfeng Dou
Liping Wang
Gul Zaib
Huixian Wu
Wang Guo
Xiaoyuan Wang
Shihao Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1552009

2,063 views

Original Research

Published on 21 Oct 2025

Recognition of HSPB8 as a potential therapeutic target for prostate cancer

in Cancer Genetics and Oncogenomics

Xun Fu
Yutao Wang
Hongjun Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1680674

1,758 views

Original Research

Published on 21 Oct 2025

In vitro cell model to dilucidate the underlying molecular mechanism associated with ophthalmic manifestation of congenital disorders of glycosylation: studying an ALG2-CDG patient

in Genetics of Common and Rare Diseases

Marisa Angelica Cubilla
Ana Clara Sclausero
Mariano Bisbal
Carla Gabriela Asteggiano

Frontiers in Genetics

doi 10.3389/fgene.2025.1678103

1,607 views

Case Report

Accepted on 20 Oct 2025

Retinitis Pigmentosa and Sensorineural Deafness Associated with a De Novo DHX16 Mutation: Case Report

in Genetics of Common and Rare Diseases

Lei Wang
Jiyong Gao
Meng Sun
Li Fan
Shuhua Wang
Xue Li
Shuangyu Gu
Bingjuan Han

Frontiers in Genetics

498 views

Original Research

Published on 20 Oct 2025

DLL1 haploinsufficiency in prenatal brain anomalies: a retrospective analysis of 6q terminal deletions

in Cytogenomics

Tingting Ge
Xiaojuan Lin
Xinyuan Tian
Xiaoyu Song
Bingbo Zhou
Ling Hui
Xiaozhuan Wang
Zhiqiang Zhang
Chuan Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1640775

1,285 views

Original Research

Published on 17 Oct 2025

Genetic and clinical landscape of Duchenne muscular dystrophy in Guatemala: insights from a national study

in Genetics of Common and Rare Diseases

M. Orozco
E. Kestler
G. Ramirez
G. Silva
J. Cabrera
S. De la Vega
A. Al Khleifat

Frontiers in Genetics

doi 10.3389/fgene.2025.1595423

1,868 views
1 citation

Case Report

Published on 17 Oct 2025

Case Report: von Hippel-Lindau (VHL) disease: a young female presenting with multiple organ tumors

in Genetics of Common and Rare Diseases

Jingyuan Li
Yun Ti
Xiao Yang
Keqiang Yan
Tongshuai Chen
Tao Guo
Qin Hu
Cheng Zhang
Peili Bu

Frontiers in Genetics

doi 10.3389/fgene.2025.1676039

1,803 views

Original Research

Published on 17 Oct 2025

Genome-wide identification of selection signals in fat-tailed and thin-tailed sheep populations

in Livestock Genomics

Lei Gao
Yiyuan Zhang
Bin Zhang
Weifeng Peng
Yucheng Liu
Zhenliang Zhang
Jingjing Wang
Pengcheng Wan
Hua Yang
Zongsheng Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1581914

1,576 views

Original Research

Published on 17 Oct 2025

Association of APOA5 rs2075291 and CIDEB rs2144492 polymorphisms with hypertriglyceridemia in individuals with traditional Chinese medicine dampness syndrome: a case-control study

in Applied Genetic Epidemiology

Na Liu
Hongli Zeng
Xiangsheng Cai
Shuo Yang
Xinyan Chen
Guli Jiang
Jiamin Yuan
Jianxiong Cai
Hui Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1654501

1,251 views

Original Research

Published on 16 Oct 2025

A novel deletion upstream of POU3F4 in a Chinese family with X-linked deafness 2 and a literature review

in Genetics of Common and Rare Diseases

Yanting Yang
Shengwen Huang
Yao Liu
Dan Mu
Ting Bai
Xiaosha Jing
Lingling Xing
Hongqian Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1641999

1,694 views

Original Research

Published on 16 Oct 2025

Whole exome sequencing identifies concurrent LDLR and ABCG8 mutations in a Saudi family with familial hypercholesterolemia and Sitosterolaemia

in Genetics of Common and Rare Diseases

Abdulrahman Hummadi
Dhayf Alrahman Mutawwam
Babajan Banaganapalli
Fai Alsubhi
Naji J. Aljohani
Ali J. Alhagawy
Turki Algohani
Ibrahim Fallatah
Mohammed Y. Daghriry
Rawan K. Alharbi

Frontiers in Genetics

doi 10.3389/fgene.2025.1679594

2,406 views

Original Research

Published on 16 Oct 2025

Transcriptome profiling of hypothalamus-pituitary-ovary axis provides insights into egg-laying interval differences between european meat pigeons and shiqi pigeons

in Livestock Genomics

Xinlei Wang
Liyu Yang
Ruiting Li
Liheng Zhang
Zhanbing Han
Runzhi Wang
Qiang Li
Dingding Zhang
Mingjun Yang
Pengkun Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1676255

1,762 views

Original Research

Published on 16 Oct 2025

A novel dinucleotide variant at 5′ splice sites in the F8 gene causes exon 19 skipping in a Chinese family with hemophilia A

in Statistical Genetics and Methodology

Xunzhao Zhou
Qi Yang
Qiuli Chen
Sheng Yi
Shengkai Wei
Jingsi Luo
Dahua Meng
Zailong Qin
Shujie Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1686184

1,437 views

Original Research

Published on 16 Oct 2025

CGSDA: inferring snoRNA-disease associations via ChebNetII and GatedGCN

in Computational Genomics

Yongfu Zou
Yusong Lu
Shanghui Lu
Zhanliang Wei
Le Li
Shuilin Liao
Ting Zeng
Yi Zhang
Rui Miao

Frontiers in Genetics

doi 10.3389/fgene.2025.1684484

1,233 views

Original Research

Published on 16 Oct 2025

Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis

in Cancer Genetics and Oncogenomics

Yun Chen
Ping Li
Yang Wang
Shuai Shen
Ni Chen
Hao Peng
Zheyuan Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1655262

1,597 views

16,451 articles

articles

Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia

Case Report: a novel missense variant of FGD5 in a family with tetralogy of Fallot

A newly discovered Lnc-PDZD7-3 increased metastatic and proliferative potential of lung adenocarcinoma cells via modulating FN1/fibronectin signaling

aiGeneR 3.0: an enhanced deep network model for resistant strain identification and multi-drug resistance prediction in Escherichia coli causing urinary tract infection using next-generation sequencing data

Correction: Heat shock protein 27 phosphorylation state is associated with cancer progression

A novel frameshift variant of PAX3 in a Chinese Yugur family with Waardenburg syndrome type 1

S100A10 knockdown exacerbates phenylephrine-induced cardiomyocyte hypertrophy via modulating mitochondrial oxidative phosphorylation

Editorial: Decoding complexity: genomic, epigenomic, and environmental dynamics in developmental and neurogenetic disorders

Case Report: Clinical and molecular features of a radiosensitive autoimmune polyendocrine syndrome type 1 patient with oral carcinoma

A novel mechanism by which c-MYC is aberrantly activated by epigenetic silencing of its antisense lncRNA in colon cancer

Recognition of HSPB8 as a potential therapeutic target for prostate cancer

In vitro cell model to dilucidate the underlying molecular mechanism associated with ophthalmic manifestation of congenital disorders of glycosylation: studying an ALG2-CDG patient

Retinitis Pigmentosa and Sensorineural Deafness Associated with a De Novo DHX16 Mutation: Case Report

DLL1 haploinsufficiency in prenatal brain anomalies: a retrospective analysis of 6q terminal deletions

Genetic and clinical landscape of Duchenne muscular dystrophy in Guatemala: insights from a national study

Case Report: von Hippel-Lindau (VHL) disease: a young female presenting with multiple organ tumors

Genome-wide identification of selection signals in fat-tailed and thin-tailed sheep populations

Association of APOA5 rs2075291 and CIDEB rs2144492 polymorphisms with hypertriglyceridemia in individuals with traditional Chinese medicine dampness syndrome: a case-control study

A novel deletion upstream of POU3F4 in a Chinese family with X-linked deafness 2 and a literature review

Whole exome sequencing identifies concurrent LDLR and ABCG8 mutations in a Saudi family with familial hypercholesterolemia and Sitosterolaemia

Transcriptome profiling of hypothalamus-pituitary-ovary axis provides insights into egg-laying interval differences between european meat pigeons and shiqi pigeons

A novel dinucleotide variant at 5′ splice sites in the F8 gene causes exon 19 skipping in a Chinese family with hemophilia A

CGSDA: inferring snoRNA-disease associations via ChebNetII and GatedGCN

Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis