Frontiers in Genetics | Applied Genetic Epidemiology

Original Research

Published on 17 Jun 2021

Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility

in Applied Genetic Epidemiology

Junke Wang
Alyssa I. Clay-Gilmour
Ezgi Karaesmen
Abbas Rizvi
Qianqian Zhu
Li Yan
Leah Preus
Song Liu
Yiwen Wang
Elizabeth Griffiths

Frontiers in Genetics

doi 10.3389/fgene.2021.554948

6,925 views
16 citations

Original Research

Published on 11 Jun 2021

Whole-Exome Sequencing Analysis of Human Semen Quality in Russian Multiethnic Population

in Applied Genetic Epidemiology

Semyon Kolmykov
Gennady Vasiliev
Ludmila Osadchuk
Maxim Kleschev
Alexander Osadchuk

Frontiers in Genetics

doi 10.3389/fgene.2021.662846

7,266 views
7 citations

Original Research

Published on 11 Jun 2021

The rs12617336 and rs17574 Dipeptidyl Peptidase-4 Polymorphisms Are Associated With Hypoalphalipoproteinemia and Dipeptidyl Peptidase-4 Serum Levels: A Case-Control Study of the Genetics of Atherosclerotic Disease (GEA) Cohort

in Applied Genetic Epidemiology

Gilberto Vargas-Alarcón
María del Carmen González-Salazar
Christian Vázquez-Vázquez
Adrián Hernández-Díaz Couder
Fausto Sánchez-Muñoz
Juan Reyes-Barrera
Sergio A. Criales-Vera
Marco Sánchez-Guerra
Citlalli Osorio-Yáñez
Rosalinda Posadas-Sánchez

Frontiers in Genetics

doi 10.3389/fgene.2021.592646

2,488 views
9 citations

Original Research

Published on 08 Jun 2021

Association of Interleukin-6 Signaling and C-Reactive Protein With Intracranial Aneurysm: A Mendelian Randomization and Genetic Correlation Study

in Applied Genetic Epidemiology

Peng-Peng Niu
Xue Wang
Yu-Ming Xu

Frontiers in Genetics

doi 10.3389/fgene.2021.679363

6,043 views
10 citations

Original Research

Published on 27 May 2021

Liver and Kidney Function Biomarkers, Blood Cell Traits and Risk of Severe COVID-19: A Mendelian Randomization Study

in Applied Genetic Epidemiology

Kai Wang
Minghan Qu
Lin Ding
Xian Shi
Chaolong Wang
Shanshan Cheng
Xingjie Hao

Frontiers in Genetics

doi 10.3389/fgene.2021.647303

7,633 views
11 citations

Original Research

Published on 26 May 2021

Appraising the Causal Association of Plasma Homocysteine Levels With Atrial Fibrillation Risk: A Two-Sample Mendelian Randomization Study

in Applied Genetic Epidemiology

Songzan Chen
Fangkun Yang
Tian Xu
Yao Wang
Kaijie Zhang
Guosheng Fu
Wenbin Zhang

Frontiers in Genetics

doi 10.3389/fgene.2021.619536

3,980 views
5 citations

Brief Research Report

Published on 13 May 2021

Genetic Landscape of Rare Autoinflammatory Disease Variants in Qatar and Middle Eastern Populations Through the Integration of Whole-Genome and Exome Datasets

in Applied Genetic Epidemiology

Parul Sharma
Abhinav Jain
Vinod Scaria

Frontiers in Genetics

doi 10.3389/fgene.2021.631340

5,078 views
3 citations

Brief Research Report

Published on 10 May 2021

Polygenic Risk for Insomnia in Adolescents of Diverse Ancestry

in Applied Genetic Epidemiology

Tengfei Ma
Honglei Chen
Qing Lu
Xiaoran Tong

Frontiers in Genetics

doi 10.3389/fgene.2021.654717

3,392 views
7 citations

Original Research

Published on 10 May 2021

Identifying Susceptibility Loci for Cutaneous Squamous Cell Carcinoma Using a Fast Sequence Kernel Association Test

in Applied Genetic Epidemiology

Manyan Huang
Chen Lyu
Xin Li
Abrar A. Qureshi
Jiali Han
Ming Li

Frontiers in Genetics

doi 10.3389/fgene.2021.657499

2,727 views
2 citations

Original Research

Published on 01 Apr 2021

A Mendelian Randomization Study of Plasma Homocysteine Levels and Cerebrovascular and Neurodegenerative Diseases

in Applied Genetic Epidemiology

Weishi Liu
Luyang Zhang
Shen Li
Chen Liu
Ying Tong
Hui Fang
Rui Zhang
Bo Song
Zongping Xia
Yuming Xu

Frontiers in Genetics

doi 10.3389/fgene.2021.653032

8,579 views
16 citations

Original Research

Published on 25 Mar 2021

Genetic Variants in TNFSF4 and TNFSF8 Are Associated With the Risk of HCV Infection Among Chinese High-Risk Population

in Applied Genetic Epidemiology

Zuqiang Fu
Weihua Cai
Jianguo Shao
Hong Xue
Zhijun Ge
Haozhi Fan
Chen Dong
Chunhui Wang
Jinwei Zhang
Chao Shen

Frontiers in Genetics

doi 10.3389/fgene.2021.630310

3,773 views
7 citations

Brief Research Report

Published on 17 Mar 2021

Initial Insights Into the Genetic Epidemiology of SARS-CoV-2 Isolates From Kerala Suggest Local Spread From Limited Introductions

in Applied Genetic Epidemiology

Chandni Radhakrishnan
Mohit Kumar Divakar
Abhinav Jain
Prasanth Viswanathan
Rahul C. Bhoyar
Bani Jolly
Mohamed Imran
Disha Sharma
Mercy Rophina
Gyan Ranjan

Frontiers in Genetics

doi 10.3389/fgene.2021.630542

7,801 views
19 citations

Original Research

Published on 05 Mar 2021

Biologically Enhanced Genome-Wide Association Study Provides Further Evidence for Candidate Loci and Discovers Novel Loci That Influence Risk of Anterior Cruciate Ligament Rupture in a Dog Model

in Applied Genetic Epidemiology

Lauren A. Baker
Mehdi Momen
Rachel McNally
Mark E. Berres
Emily E. Binversie
Susannah J. Sample
Peter Muir

Frontiers in Genetics

doi 10.3389/fgene.2021.593515

5,740 views
14 citations

Original Research

Published on 04 Mar 2021

Iron Status May Not Affect Amyotrophic Lateral Sclerosis: A Mendelian Randomization Study

in Applied Genetic Epidemiology

Jiahao Cai
Xiong Chen
Hongxuan Wang
Zixin Wei
Mei Li
Xiaoming Rong
Xiangpen Li
Ying Peng

Frontiers in Genetics

doi 10.3389/fgene.2021.617245

7,347 views
10 citations

Original Research

Published on 02 Mar 2021

Genome-Wide Identification of Rare and Common Variants Driving Triglyceride Levels in a Nevada Population

in Applied Genetic Epidemiology

Robert W. Read
Karen A. Schlauch
Vincent C. Lombardi
Elizabeth T. Cirulli
Nicole L. Washington
James T. Lu
Joseph J. Grzymski

Frontiers in Genetics

doi 10.3389/fgene.2021.639418

8,601 views
11 citations

Original Research

Published on 22 Feb 2021

The Intersection of the Genetic Architectures of Orofacial Clefts and Normal Facial Variation

in Applied Genetic Epidemiology

Karlijne Indencleef
Hanne Hoskens
Myoung Keun Lee
Julie D. White
Chenxing Liu
Ryan J. Eller
Sahin Naqvi
George L. Wehby
Lina M. Moreno Uribe
Jacqueline T. Hecht

Frontiers in Genetics

doi 10.3389/fgene.2021.626403

5,594 views
21 citations